SUPERNOVA

SUPERNOVA

50:1 CONCENTRATION

SUPERNOVA is 2.5 times stronger than original formula (20:1).
COST COMPARISON: 1/4 kg of original is $90 so it will cost you $225 to match one 1/4 kg of SUPERNOVA!

INGREDIENTS

​Reishi
“THE MUSHROOM OF IMMORTALITY” Liver Regeneration, Neuroprotector, Anti Cancer, AMPK activator, mTOR inhibitor

1. ReishiMax, mushroom based dietary supplement, inhibits adipocyte differentiation, stimulates glucose uptake and activates AMPK
2. How Reishi Combats Aging
3. How Lingzhi Mushrooms (Reishi) Combats Aging, Disease and Cancer
4. Anti-Tumor Effects of Ganoderma lucidum (Reishi) in Inflammatory Breast Cancer in In Vivo and In Vitro Models
5. Ganoderma lucidum (Reishi) suppresses proliferation and migration of breast cancer cells via inhibiting Wnt/β-catenin signaling
6. Abstract 5556: Enhancing response of Ganoderma lucidum (Reishi) and lapatinib in HER2+ inflammatory breast cancer cells
7. Abstract 1992: Ganoderma lucidum (Reishi) induces autophagy in inflammatory breast cancer by regulation of the mTOR signaling pathway
8. Abstract 1987: Ganoderma lucidum (Reishi) suppresses key protein synthesis initiation molecules in inflammatory breast cancer
9. Abstract 4228: Ganoderma lucidum (Reishi) reduces inflammatory breast cancer progression via protein synthesis inhibition
10. Abstract 3212: Ganoderma lucidum (Reishi) chemosensitizes EGFR-overexpressing inflammatory breast cancer cells to erlotinib
11. Anti-Amnesic Effect of Fermented Ganoderma lucidum Water Extracts by Lactic Acid Bacteria on Scopolamine-Induced Memory Impairment in Rats
12. Sporoderm-Broken Spores of Ganoderma lucidum Inhibit the Growth of Lung Cancer: Involvement of the Akt/mTOR Signaling Pathway
13. Evaluation of in vivo antioxidant activities of Ganoderma lucidum polysaccharides in STZ-diabetic rats
14. Antihyperglycemic Effect of Ganoderma Lucidum Polysaccharides on Streptozotocin-Induced Diabetic Mice
15. Anti-diabetic effects of Ganoderma lucidum
16. International Journal of Medicinal Mushrooms
17. Hypoglycemic effects of Ganoderma lucidum polysaccharides in type 2 diabetic mice
18. Antagonizing β-amyloid peptide neurotoxicity of the anti-aging fungus Ganoderma lucidum
19. Neuroprotective effect of preadministration with Ganoderma lucidum spore on rat hippocampus
20. Polysaccharides from Ganoderma lucidum Promote Cognitive Function and Neural Progenitor Proliferation in Mouse Model of Alzheimer’s Disease
21. Ganoderma lucidum reduces obesity in mice by modulating the composition of the gut microbiota
22. Ganoderma lucidum, a new prebiotic agent to treat obesity?
23. Corrigendum: Ganoderma lucidum reduces obesity in mice by modulating the composition of the gut microbiota
24. Hypoglycemic effect and mechanism of a proteoglycan from Ganoderma Lucidumonstreptozotocin-induced type 2 diabetic rats
25. Triterpenes From Ganoderma Lucidum Induce Autophagy in Colon Cancer Through the Inhibition of p38 Mitogen-Activated Kinase (p38 MAPK)
26. Recombinant Lz-8 from Ganoderma lucidum induces endoplasmic reticulum stress-mediated autophagic cell death in SGC-7901 human gastric cancer cells
27. Anti-cancer properties of triterpenoids isolated from Ganoderma lucidum – a review
28. Methanolic Extract of Ganoderma lucidum Induces Autophagy of AGS Human Gastric Tumor Cells
29. Antidepressant-like effects of a water-soluble extract from the culture medium of Ganoderma lucidum mycelia in rats
30. Ganoderma lucidum Protects Dopaminergic Neuron Degeneration through Inhibition of Microglial Activation

​Gynostemma
“THE HERB OF IMMORTALITY” Combats Aging, Strengthens Heart, Lifts Spirits, AMPK activator

1. Gynostemma pentaphyllum Tea Improves Insulin Sensitivity in Type 2 Diabetic Patients
2. New dammarane-type glucosides as potential activators of AMP-activated protein kinase (AMPK) from Gynostemma pentaphyllum
3. Heat-processed Gynostemma pentaphyllum extract improves obesity in ob/ob mice by activating AMP-activated protein kinase
4. Antiobesity effect of Gynostemma pentaphyllum extract (actiponin): A randomized, double‐blind, placebo‐controlled trial
5. Potential Hypoglycemic Effect of an Ethanol Extract of Gynostemma pentaphyllum in C57BL/KsJ-db/db Mice
6. Chemical constituents from a Gynostemma laxum and their antioxidant and neuroprotective activities
7. Inhibitory Effect of Damulin B from Gynostemma pentaphyllum on Human Lung Cancer Cells
8. The Effect of Gynostemma Pentaphyllum Extract on DNA Damage of Aging Rats
9. Anti-Oxidative Effect of Gynostemma and Hawthorn Extracts on the Aging Mouse Model Induced by D-galactose
10. Gynostemma pentaphyllum Exhibit Differential Induction of Cell Cycle Arrest in H460 and A549 Cancer Cells
11. [A preliminary observation of preventive and blocking effect of Gynostemma pentaphyllum (Thunb) Makino on esophageal cancer in rats].
12. Anti-cancer effects of Gynostemma pentaphyllum (Thunb.) Makino (Jiaogulan)
13. EFFECTS OF GYNOSTEMMA PENTAPHYLLUM MAKINO ON THE IMMUNOLOGICAL FUNCTION OF CANCER PATIENTS
14. Antidiabetic Effect of Gynostemma pentaphyllum Tea in Randomly Assigned Type 2 Diabetic Patients[*]
15. Herbal Extract of Gynostemma Pentaphyllum Decreases Hepatic Glucose Output in Type 2 Diabetic Goto-Kakizaki Rats
16. Hypoglycemic Activity of Polysaccharide from Gynostemma pentaphyllum on Type 2 Diabetic Rats and its Mechanism
17. Two Novel Anti-Inflammatory 21-Nordammarane Saponins from Tetraploid Jiaogulan (Gynostemma pentaphyllum)
18. Phytopreventative Anti-Hyperlipidemic Effects Of Gynostemma Pentaphyllum In Rats
19. Gynostemma pentaphyllum exhibits anti-inflammatory properties and modulates antimicrobial peptide expression in the urinary bladder
20. Gypenoside L, Isolated from Gynostemma pentaphyllum, Induces Cytoplasmic Vacuolation Death in Hepatocellular Carcinoma Cells through Reactive-Oxygen-Species-Mediated Unfolded Protein Response
21. Isolation and antitumor activities of acidic polysaccharide from Gynostemma pentaphyllum Makino
22. Chemical Composition of Five Commercial Gynostemma pentaphyllum Samples and Their Radical Scavenging, Antiproliferative, and Anti-inflammatory Properties
23. Two new saponins from tetraploid jiaogulan (Gynostemma pentaphyllum), and their anti-inflammatory and α-glucosidase inhibitory activities
24. Long-term oral administration of Gynostemma pentaphyllum extract attenuates airway inflammation and Th2 cell activities in ovalbumin-sensitized mice
25. Characterization of a Novel Alkali-Soluble Heteropolysaccharide from Tetraploid Gynostemma pentaphyllum Makino and Its Potential Anti-inflammatory and Antioxidant Properties
26. Neuroprotective Effects of Herbal Ethanol Extracts from Gynostemma pentaphyllum in the 6-Hydroxydopamine-Lesioned Rat Model of Parkinson’s Disease
27. Anxiolytic Effects of Herbal Ethanol Extract from Gynostemma pentaphyllum in Mice after Exposure to Chronic Stress
28. Preconditioning of brain slices against hypoxia induced injury by a Gynostemma pentaphyllum extract – Stimulation of anti-oxidative enzyme expression
29. Protective effects of crude polysaccharide from Gynostemma pentaphyllum on swimming exercise-induced oxidative stress in rat.
30. Antidepressant Activities of Extracts from Gynostemma pentaphyllum(Thunb.) Makino

Shilajit
“DESTROYER OF WEAKNESS” Contains All Trace Minerals & the Critical Fulvic Acid – 2nd only to DNA in Importance

1. Anti-Inflammatory and Anti-Arthritic Efficacy and Safety of Purified Shilajit in Moderately Arthritic Dogs
2. Shilajit attenuates streptozotocin induced diabetes mellitus and decrease in pancreatic islet superoxide dismutase activity in rats
3. Can Nutraceuticals Prevent Alzheimer’s Disease? Potential Therapeutic Role of a Formulation Containing Shilajit and Complex B Vitamins
4. EFFECTS OF SHILAJITON MEMORY, ANXIETY AND BRAINMONOAMINES IN RATS
5. Effects of shilajit and its active constituents on learning and memory in rats
6. Shilajit: A Natural Phytocomplex with Potential Procognitive Activity
7. Shilajit: A Humic Matter Panacea for Cancer
8. Shilajit attenuates streptozotocin induced diabetes mellitus and decrease in pancreatic islet superoxide dismutase activity in rats
9. Effect of shilajit on blood glucose and lipid profile in alloxan-induced diabetic rats
10. Shilajit‐induced potentiation of the hypoglycaemic action of insulin and inhibition of streptozotocin induced diabetes in rat
11. Phenolic antioxidant-chromium complexes for treatment or prevention of type 2 diabetes or glucose intolerance
12. Effect of Shilajit on the Levels of Pro-inflammatory and Anti-inflammation Cytokines in Hepatic Injury in Male Rats
13. Oxidative Stress Induced by Lead and Antioxidant Potential of Certain Adaptogens
14. Chemistry of shilajit, an immunomodulatory Ayurvedic rasayan
15. Antiepileptic and antipsychotic activities of standardized Śilājatu (Shilajit) in experimental animals
16. Glycine- and GABA-mimetic Actions of Shilajit on the Substantia Gelatinosa Neurons of the Trigeminal Subnucleus Caudalis in Mice
17. Effect of Shilajit enriched diet on immunity, antioxidants, and disease resistance in Macrobrachium rosenbergii (de Man) against Aeromonas hydrophila
18. Effect of Shilajit on body weight of young rats
19. Method for treating pain and inflammation associated with arthritis using chromium-three cation in combination with phyllanthus emblica and shilajit
20. Standardization and Anti-Inflammatory Activity of Shilajit

​Chaga
​”DIAMOND OF THE FOREST” ” THE GIFT FROM GOD” Super Antioxidant, Supports Overall Health, Anti Stress, Anti Aging

1. Anti-diabetic effects of Inonotus obliquus polysaccharides-chromium (III) complex in type 2 diabetic mice and its sub-acute toxicity evaluation in normal mice
2. Suppression of Adiposity and Improvement of Fat Metabolism in High-fat Diet-induced Obese Mice Treated with an Inonotus obliquus Extract [2016]
3. Improvement of Lipid Metabolism of Inonotus obliquus and roasted Inonotus obliquus extracts in mice a fed high-fat diet
4. Medicinal Mushrooms and Cancer
5. Anti-cancer effect and structural characterization of endo-polysaccharide from cultivated mycelia of Inonotus obliquus
6. Optimization of ultrasonic/microwave assisted extraction (UMAE) of polysaccharides from Inonotus obliquus and evaluation of its anti-tumor activities
7. Structure determination of inonotsuoxides A and B and in vivo anti-tumor promoting activity of inotodiol from the sclerotia of Inonotus obliquus
8. Antitumor activity of water extract of a mushroom, Inonotus obliquus, against HT‐29 human colon cancer cells
9. Lanostane-type triterpenoids from the sclerotia of Inonotus obliquus possessing anti-tumor promoting activity
10. Anticancer activity of subfractions containing pure compounds of Chaga mushroom (Inonotus obliquus) extract in human cancer cells and in Balbc/c mice bearing Sarcoma-180 cells
11. Anti-inflammatory and anticancer activities of extracts and compounds from the mushroom Inonotus obliquus
12. Ergosterol peroxide from Chaga mushroom (Inonotus obliquus) exhibits anti-cancer activity by down-regulation of the β-catenin pathway in colorectal cancer
13. Anti-diabetic effects of Inonotus obliquus polysaccharides-chromium (III) complex in type 2 diabetic mice and its sub-acute toxicity evaluation in normal mice
14. Hypoglycemic and Antioxidative Effects of Fermented Chaga Mushroom (Inonotus obliquus) on Streptozotocin-induced Diabetic Rats
15. Anti-diabetic effects of Inonotus obliquus polysaccharides in streptozotocin-induced type 2 diabetic mice and potential mechanism via PI3K-Akt signal pathway
16. Protective Effect of Polysaccharides from Inonotus obliquus on Streptozotocin-Induced Diabetic Symptoms and Their Potential Mechanisms in Rats
17. Amelioration of scopolamine induced cognitive dysfunction and oxidative stress by Inonotus obliquus – a medicinal mushroom
18. Oxidative stress response of Inonotus obliquus induced by hydrogen peroxide
19. In Vitro investigation on antioxidative effect of Inonotus obliquus extracts against oxidative stress on PC12 cells
20. Antidiabetic activities of polysaccharides separated from Inonotus obliquus via the modulation of oxidative stress in mice with streptozotocin-induced diabetes
21. Continuous intake of the Chaga mushroom (Inonotus obliquus) aqueous extract suppresses cancer progression and maintains body temperature in mice
22. Anti-Obesity Activity, Anti-Cancer Activity and Single Oral Dose Toxicity of Inonotus xeranticus Extracts
23. Insulin‐Sensitizing and Beneficial Lipid‐Metabolic Effects of the Water‐Soluble Melanin Complex Extracted from Inonotus obliquus
24. Identification of Inonotus obliquus and Analysis of Antioxidation and Antitumor Activities of Polysaccharides
25. Inonotus obliquus protects against oxidative stress-induced apoptosis and premature senescence
26. Anti-inflammatory effect of Inonotus obliquus, Polygala senega L., and Viburnum trilobum in a cell screening assay
27. Anti-Oxidant and Anti-Inflammatory Activities of Inonotus obliquus and Germinated Brown Rice Extracts
28. Pleurotus tuber-regium Polysaccharides Attenuate Hyperglycemia and Oxidative Stress in Experimental Diabetic Rats
29. [Triterpenoids from Inonotus obliquus protect mice against oxidative damage induced by CCl4].
30. Chaga mushroom extract inhibits oxidative DNA damage in lymphocytes of patients with inflammatory bowel disease

Eleuthero
“SIBERIAN GINSENG” Memory Booster, Anti Stress & Fatigue

1. Assessing the Anticancer Potential of NaturalHealth Products (Lemongrass, Hibiscus, andEleuthero Ginseng) Against Breast Cancer Models
2. EFFECTS OF SIBERIAN GINSENG (ELEUTHEROCOCCUS SENTICOSUS MAXIM.) ON ELDERLY QUALITY OF LIFE: A RANDOMIZED CLINICAL TRIAL
3. Eleutherococcus senticosus reduces cardiovascular stress response in healthy subjects: a randomized, placebo‐controlled trial
4. The Effect of Siberian Ginseng (Eleutherococcus Senticosus) on Substrate Utilization and Performance during Prolonged Cycling
5. The influence of active components of Eleutherococcus senticosus on cellular defence and physical fitness in man
6. Hypoglycemic Effect of Syringin from Eleutherococcus senticosus in Streptozotocin-Induced Diabetic Rats
7. Eleutheroside E, An Active Component of Eleutherococcus senticosus, Ameliorates Insulin Resistance in Type 2 Diabetic db/db Mice
8. Increase of β-Endorphin Secretion by Syringin, an Active Principle of Eleutherococcus senticosus, to Produce Antihyperglycemic Action in Type 1-like Diabetic Rats
9. Anti-diabetic and Hypoglycemic Effect of Eleutherococcus spp.
10. MICROWAVE‐ASSISTED SEED ESSENTIAL OIL OF ELEUTHEROCOCCUS SENTICOSUS AND ITS ANTIOXIDANT AND FREE RADICAL‐SCAVENGING ACTIVITIES
11. Release of acetylcholine by syringin, an active principle of Eleutherococcus senticosus, to raise insulin secretion in Wistar rats
12. Eleutheroside E, An Active Component of Eleutherococcus senticosus, Ameliorates Insulin Resistance in Type 2 Diabetic db/db Mice
13. Hypoglycemic Effect of Syringin from Eleutherococcus senticosus in Streptozotocin-Induced Diabetic Rats
14. The Effect of Eight Weeks of Supplementationwith Eleutherococcus senticosus on EnduranceCapacity and Metabolism in Human
15. Increase of β-Endorphin Secretion by Syringin, an Active Principle of Eleutherococcus senticosus, to Produce Antihyperglycemic Action in Type 1-like Diabetic Rats
16. A Herbal Composition of Scutellaria baicalensis and Eleutherococcus senticosus Shows Potent Anti-Inflammatory Effects in an Ex Vivo Human Mucosal Tissue Model
17. Effect of light on oxidative stress, secondary metabolites and induction of antioxidant enzymes in Eleutherococcus senticosus somatic embryos in bioreactor
18. Isolation and Hypoglycemic Activity of Eleutherans A, B, C, D, E, F, and G: Glycans of Eleutherococcus senticosus Roots
19. Siberian ginseng (Eleutherococcus senticosus): current status as an adaptogen [1985]
20. Differential antioxidant and quinone reductase inducing activity of American, Asian, and Siberian ginseng

Rhodiola
​”THE GOLDEN ROOT” Mood Enhancer, Combats Anxiety & Depression, mTOR inhibitor

1. Rhodiola crenulata extract suppresses hepatic gluconeogenesis via activation of the AMPK pathway
2. Rhodiola crenulata extract regulates hepatic glycogen and lipid metabolism via activation of the AMPK pathway
3. Rhodiola rosea extracts and salidroside decrease the growth of bladder cancer cell lines via inhibition of the mTOR pathway and induction of autophagy
4. Protective Effects of Rhodiola Crenulata Extract on Hypoxia-Induced Endothelial Damage via Regulation of AMPK and ERK Pathways
5. Rhodiola crenulata Attenuates γ-Ray Induced Cellular Injury via Modulation of Oxidative Stress in Human Skin Cells
6. Antioxidative Effects of Rhodiola Genus: Phytochemistry and Pharmacological Mechanisms against the Diseases
7. Rhodiola rosea L.: an Herb with Anti-Stress, Anti-Aging, and Immunostimulating Properties for Cancer Chemoprevention
8. Rhodiola crenulata inhibits Wnt/β-catenin signaling in glioblastoma
9. Rosenroot (Rhodiola): Potential Applications in Aging-related Diseases
10. Rhodiola: A Promising Anti-Aging Chinese Herb
11. Study of anti-aging and anti-dementia effects of Rhodosin on aging rats and experimental dementia rats
12. Protection of human cultured cells against oxidative stress by Rhodiola rosea without activation of antioxidant defenses
13. Rhodiola algida improves chemotherapy-induced oral mucositis in breast cancer patients
14. The effect of a Rhodiola rosea extract on the incidence of recurrences of a superficial bladder cancer (experimental clinical research)
15. Rhodiola crenulata Induces Death and Inhibits Growth of Breast Cancer Cell Lines
16. Free radical scavenging property and antiproliferative activity of Rhodiola imbricata Edgew extracts in HT-29 human colon cancer cells
17. Rhodiola crenulata induces an early estrogenic response and reduces proliferation and tumorsphere formation over time in MCF7 breast cancer cells
18. Aqueous extract of Rhodiola imbricata rhizome inhibits proliferation of an erythroleukemic cell line K-562 by inducing apoptosis and cell cycle arrest at G2/M phase
19. Effect of Rhodiola on nude mice with human breast cancer xenografts
20. The effect of Rhodiola kirilowiiextracts ontumor-induced angiogenesis in mice
21. Evaluation of Rhodiola crenulata and Rhodiola rosea for management of Type II diabetes and hypertension.
22. Anti-Diabetes Functionality of Kefir Culture-Mediated Fermented Soymilk Supplemented with Rhodiola Extracts
23. Rhodiola crenulata root ameliorates derangements of glucose and lipid metabolism in a rat model of the metabolic syndrome and type 2 diabetes
24. Antioxidative effects of Cinnamomi cassiae and Rhodiola rosea extracts in liver of diabetic mice
25. Citrus aurantium and Rhodiola rosea in combination reduce visceral white adipose tissue and increase hypothalamic norepinephrine in a rat model of diet-induced obesity
26. [Investigation of a compound, compatibility of Rhodiola crenulata, Cordyceps militaris, and Rheum palmatum, on metabolic syndrome treatment II – improving obesity].
27. Evaluation of Rhodiola rosea supplementation on skeletal muscle damage and inflammation in runners following a competitive marathon
28. Early use of Chinese drug rhodiola compound for patients with post-trauma and inflammation in prevention of ALI/ARDS
29. In vitro protective effect of Rhodiola rosea extract against hypochlorous acid-induced oxidative damage in human erythrocytes
30. [Effects of Rhodiola rosea on level of 5-hydroxytryptamine, cell proliferation and differentiation, and number of neuron in cerebral hippocampus of rats with depression induced by chronic mild stress].

Wild Ginseng
​”KING OF HERBS” Anti Stress & Fatigue, Promotes Strength & Endurance, AMPK activator

1. Ginsenoside Rc, an active component of Panax ginseng, stimulates glucose uptake in C2C12 myotubes through an AMPK-dependent mechanism
2. Red ginseng abrogates oxidative stress via mitochondria protection mediated by LKB1-AMPK pathway
3. Korean Red Ginseng attenuates ethanol-induced steatosis and oxidative stress via AMPK/Sirt1 activation
4. Fermented Ginseng Attenuates Hepatic Lipid Accumulation and Hyperglycemia through AMPK Activation
5. Korean red ginseng (Panax ginseng) improves insulin sensitivity and attenuates the development of diabetes in Otsuka Long-Evans Tokushima fatty rats
6. Anti-diabetic effect of black ginseng extract by augmentation of AMPK protein activity and upregulation of GLUT2 and GLUT4 expression in db/db mice
7. An enzymatically fortified ginseng extract inhibits proliferation and induces apoptosis of KATO3 human gastric cancer cells via modulation of Bax, mTOR, PKB and IκBα
8. Red ginseng extracts attenuate skin inflammation in atopic dermatitis through p70 ribosomal protein S6 kinase activation
9. Role of ginsenosides, the main active components of Panax ginseng, in inflammatory responses and diseases
10. Studies on the Anti – aging Action of Korean Ginseng
11. Effects of red ginseng extract on UVB irradiation-induced skin aging in hairless mice
12. Effects of ginseng saponins isolated from red ginseng on ultraviolet B-induced skin aging in hairless mice
13. The Preventive Effect of Ginseng with Du-Zhong Leaf of Protein Metabolism in Aging
14. Nanoemulsion comprising metabolites of ginseng saponin as an active component and a method for preparing the same, and a skin-care composition for anti-aging containing the same
15. Cancer Prevention and Therapeutics: Panax Ginseng.
16. Chemistry and Cancer Preventing Activities of Ginseng Saponinsand Some Related Triterpenoid Compounds
17. Inflammation, Cancer, and Targets of Ginseng
18. In vitro anti-cancer activity and structure–activity relationships of natural products isolated from fruits of Panax ginseng
19. Cancer chemopreventive and therapeutic activities of red ginseng
20. Ginseng and Diabetes
21. American Ginseng (Panax quinquefolius L) Reduces Postprandial Glycemia in Nondiabetic Subjects and Subjects With Type 2 Diabetes Mellitus
22. Herbal remedies in the management of diabetes: Lessons learned from the study of ginseng
23. Korean red ginseng (Panax ginseng) improves glucose and insulin regulation in well-controlled, type 2 diabetes: Results of a randomized, double-blind, placebo-controlled study of efficacy and safety
24. Effect of Crude Saponin of Korean Red Ginseng on High Fat Diet-Induced Obesity in the Rat
25. Korean red ginseng (Panax ginseng) prevents obesity by inhibiting angiogenesis in high fat diet-induced obese C57BL/6J mice
26. A ginseng metabolite, compound K, induces autophagy and apoptosis via generation of reactive oxygen species and activation of JNK in human colon cancer cells
27. Ginseng treatment attenuates autophagic cell death in chronic cyclosporine nephropathy
28. Effects of Panax ginseng extract on exercise-induced oxidative stress
29. Ginseng administration protects skeletal muscle from oxidative stress induced by acute exercise in rats
30. Effect of fermented Panax ginseng extract (GINST) on oxidative stress and antioxidant activities in major organs of aged rats

Astragalus
​”SUPER IMMUNE BOOSTER” Improves Energy, Promotes Longevity, Anti Aging, Builds Qi, Preserves Telomere Length, mTOR inhibitor

1. Astragalus polysaccharides alleviates glucose toxicity and restores glucose homeostasis in diabetic states via activation of AMPK
2. Astragalus polysaccharide induces anti-inflammatory effects dependent on AMPK activity in palmitate-treated RAW264.7 cells
3. Astragalus polysaccharide stimulates glucose uptake in L6 myotubes through AMPK activation and AS160/TBC1D4 phosphorylation
4. Astragalus Polysaccharide Improves Palmitate-Induced Insulin Resistance by Inhibiting PTP1B and NF-κB in C2C12 Myotubes
5. Astragalus polysaccharide attenuates free fatty acid-induced toxicity by activating AMPK in C2C12 myoblasts
6. Astragalus saponins modulate mTOR and ERK signaling to promote apoptosis through the extrinsic pathway in HT-29 colon cancer cells
7. Astragalus polysaccharides decrease muscle wasting through Akt/mTOR, ubiquitin proteasome and autophagy signalling in 5/6 nephrectomised rats
8. Mitochondrial Protection and Anti-aging Activity of Astragalus Polysaccharides and Their Potential Mechanism
9. Anti-Aging Implications of Astragalus Membranaceus (Huangqi): A Well-Known Chinese Tonic
10. Deferring senile effect of polysaccharides from Angelica and Astragalus on aging mice
11. Anti-oxidative effect of total extract of astragalus(TEA) on aging mice
12. Research Astragalus and Cell on Aging
13. Astragalus-Based Chinese Herbs and Platinum-BasedChemotherapy for Advanced Non–Small-Cell Lung Cancer:Meta-Analysis of Randomized Trials
14. Extraction, characterization of Astragalus polysaccharides and its immune modulating activities in rats with gastric cancer
15. Astragalus saponins induce growth inhibition and apoptosis in human colon cancer cells and tumor xenograft
16. Astragalus polysaccharide injection integrated with vinorelbine and cisplatin for patients with advanced non-small cell lung cancer: effects on quality of life and survival
17. Traditional Chinese medicine Astragalus reverses predominance of Th2 cytokines and their up-stream transcript factors in lung cancer patients
18. Safety and pharmacokinetic trial of docetaxel plus an Astragalus-based herbal formula for non-small cell lung cancer patients
19. Astragalus extract inhibits destruction of gastric cancer cells to mesothelial cells by anti-apoptosis
20. Astragalus Polysaccharides: An Effective Treatment for Diabetes Prevention in NOD Mice
21. Astragalus polysaccharides decreased the expression of PTP1B through relieving ER stress induced activation of ATF6 in a rat model of type 2 diabetes
22. Biological Active Ingredients of Traditional Chinese Herb Astragalus membranaceus on Treatment of Diabetes: A Systematic Review
23. Astragalus Polysaccharide Suppresses Skeletal Muscle Myostatin Expression in Diabetes: Involvement of ROS-ERK and NF-κB Pathways
24. Astragalus membranaceus-Polysaccharides Ameliorates Obesity, Hepatic Steatosis, Neuroinflammation and Cognition Impairment without Affecting Amyloid Deposition in Metabolically Stressed APPswe/PS1dE9 Mice
25. Insulin Sensitization and Anti-obesity Effects of Astragalus Polysaccharide on High Fat Diet-fed C57BL/6J Mice
26. Astragalus polysaccharide improves insulin sensitivity in KKAy mice: Regulation of PKB/GLUT4 signaling in skeletal muscle
27. Hypoglycemic effect of polysaccharide enriched extract of Astragalus membranaceus in diet induced insulin resistant C57BL/6J mice and its potential mechanism
28. Drosophila melangogaster longevity test for Astragalus membranaceus
29. Astragalus polysaccharides inhibits PCV2 replication by inhibiting oxidative stress and blocking NF-κB pathway
30. Aqueous extract of Astragalus mongholicusameliorates high cholesterol diet induced oxidativeinjury in experimental rats models

Cordyceps
“HERBAL TONIC SUPERSTAR” Boosts Energy & Improves Oxygen Utilization, Increases Endurance

1. Cordycepin Down-Regulates Multiple Drug Resistant (MDR)/HIF-1α through Regulating AMPK/mTORC1 Signaling in GBC-SD Gallbladder Cancer Cells
2. Cordycepin activates AMP‐activated protein kinase (AMPK) via interaction with the γ1 subunit
3. Cordycepin Inhibits Lipopolysaccharide (LPS)-Induced Tumor Necrosis Factor (TNF)-α Production via Activating AMP-Activated Protein Kinase (AMPK) Signaling
4. Cordyceps cicadae mycelia and its active compound HEA exert beneficial effects on blood glucose in type 2 diabetic db/db mice
5. Antiproliferative and Apoptosis-Inducing Activities of 4-Isopropyl-2,6-bis(1-phenylethyl)phenol Isolated from Butanol Fraction of Cordyceps bassiana
6. Polysaccharides from the Medicinal Mushroom Cordyceps taii Show Antioxidant and Immunoenhancing Activities in a D-Galactose-Induced Aging Mouse Model
7. Protective Effects on Mitochondria and Anti-Aging Activity of Polysaccharides from Cultivated Fruiting Bodies of Cordyceps militaris
8. [An experimental study on anti-aging action of Cordyceps extract].
9. THE PURIFICATION AND ANTIOXIDATIVE ACTIVITIES IN D‐GALACTOSE‐INDUCED AGING MICE OF A WATER‐SOLUBLE POLYSACCHARIDE FROM CORDYCEPS GUNNII (BERK.) BERK. MYCELIUM
10. Ecology‐based screen identifies new metabolites from a Cordyceps‐colonizing fungus as cancer cell proliferation inhibitors and apoptosis inducers
11. Induction of apoptosis by aqueous extract of Cordyceps militaris through activation of caspases and inactivation of Akt in human breast cancer MDA-MB-231 Cells.
12. Polysaccharide of Cordyceps sinensis Enhances Cisplatin Cytotoxicity in Non–Small Cell Lung Cancer H157 Cell Line
13. Antitumor activity of Cordyceps militaris on human cancer cell line
14. [Inhibitory effects of cordyceps extract on growth of colon cancer cells].
15. Anti-cancer Effects of CME-1, a Novel Polysaccharide, Purified from the Mycelia of Cordyceps sinensis against B16-F10 Melanoma Cells
16. A Contemporary Treatment Approach to Both Diabetes and Depression by Cordyceps sinensis, Rich in Vanadium
17. Anti-hyperglycemic Activity of Natural and Fermented Cordyceps sinensis in Rats with Diabetes Induced by Nicotinamide and Streptozotocin
18. Immunoregulatory Cordyceps sinensis increases regulatory T cells to Th17 cell ratio and delays diabetes in NOD mice
19. Effects of Extract from Solid-State Fermented Cordyceps sinensis on Type 2 Diabetes Mellitus
20. Effect of Cordyceps militaris extract and active constituents on metabolic parameters of obesity induced by high-fat diet in C58BL/6J mice
21. Effects of North Cordyceps sinensis’s Extract on the Reproductivity and Longevity of the Drosophila melangogaster
22. Anti-inflammation Effects of Cordyceps sinensis Mycelium in Focal Cerebral Ischemic Injury Rats
23. Effects of the Immunomodulatory Agent Cordyceps militaris on Airway Inflammation in a Mouse Asthma Model
24. Anti-inflammation and antioxidant effect of Cordymin, a peptide purified from the medicinal mushroom Cordyceps sinensis, in middle cerebral artery occlusion-induced focal cerebral ischemia in rats
25. A potent sphingomyelinase inhibitor from Cordyceps mycelia contributes its cytoprotective effect against oxidative stress in macrophages
26. Protective effect of Cordyceps militaris against high glucose-induced oxidative stress in human umbilical vein endothelial cells
27. Cordyceps militaris Extract Protects Human Dermal Fibroblasts against Oxidative Stress-Induced Apoptosis and Premature Senescence
28. Vanadium-Enriched Cordyceps sinensis, a Contemporary Treatment Approach to Both Diabetes and Depression in Rats
29. Increasing oxidative stress tolerance and subculturing stability of Cordyceps militaris by overexpression of a glutathione peroxidase gene
30. Effect of polysaccharide from cultured Cordyceps sinensis on immune function and anti-oxidation activity of mice exposed to 60Co

Schizandra
​”THE HERB THAT DOES IT ALL” Boosts Memory & Alertness, Supports All Organs & Bodily Functions, Relieves Fatigue

1. Huang-Lian-Jie-Du-Tang Supplemented with Schisandra chinensis Baill. and Polygonatum odoratum Druce Improved Glucose Tolerance by Potentiating Insulinotropic Actions in Islets in 90% Pancreatectomized Diabetic Rats
2. Schisandra chinensis berry extract protects against steatosis by inhibiting histone acetylation in oleic acid–treated HepG2 cells and in the livers of diet-induced obese mice
3. Protective effect of acidic polysaccharide from Schisandra chinensis on acute ethanol-induced liver injury through reducing CYP2E1-dependent oxidative stress
4. Anticancer activity of gomisin J from Schisandra chinensis fruit
5. SCP, a polysaccharide from Schisandra chinensis, induces apoptosis in human renal cell carcinoma Caki-1 cells through mitochondrial-dependent pathway via inhibition of ERK activation
6. Schisandra chinensis produces the antidepressant-like effects in repeated corticosterone-induced mice via the BDNF/TrkB/CREB signaling pathway
7. Antidepressant-like effects and cognitive enhancement of Schisandra chinensis in chronic unpredictable mild stress mice and its related mechanism
8. Downregulation of pro-inflammatory mediators by a water extract of Schisandra chinensis (Turcz.) Baill fruit in lipopolysaccharide-stimulated RAW 264.7 macrophage cells
9. Antioxidative and Cardioprotective Effects of Schisandra chinensis Bee Pollen Extract on Isoprenaline-Induced Myocardial Infarction in Rats
10. Lignans from Schisandra chinensis ameliorate cognition deficits and attenuate brain oxidative damage induced by D-galactose in rats
11. In Vivo Antioxidant Action of a Lignan-Enriched Extract of Schisandra Fruit and an Anthraquinone-Containing Extract of Polygonum Root in Comparison with Schisandrin B and Emodin
12. Metabolomics study of the therapeutic mechanism of Schisandra chinensis lignans on aging rats induced by d-galactose
13. Kudsuphilactone B, a nortriterpenoid isolated from Schisandra chinensis fruit, induces caspase-dependent apoptosis in human ovarian cancer A2780 cells
14. Constituents of Schisandra verruculosa. and Their Cytotoxic Effect on Human Cancer Cell Lines
15. Gomisin N isolated from Schisandra chinensis significantly induces anti-proliferative and pro-apoptotic effects in hepatic carcinoma
16. Antioxidant and anti-proliferative activities of five compounds from Schisandra chinensis fruit
17. Isolation of lignans from Schisandra chinensis with anti-proliferative activity in human colorectal carcinoma: Structure–activity relationships
18. Antitumor and immunomodulatory activity of a water-soluble low molecular weight polysaccharide from Schisandra chinensis (Turcz.) Baill
19. Antitumor and antiangiogenic activity of Schisandra chinensis polysaccharide in a renal cell carcinoma model
20. Schisandra chinensis fruit extract attenuates albuminuria and protects podocyte integrity in a mouse model of streptozotocin-induced diabetic nephropathy
21. Anti-diabetic effects of polysaccharides from ethanol-insoluble residue of Schisandra chinensis (Turcz.) Baill on alloxan-induced diabetic mice
22. In Vitro Antioxidant activities and anti-diabetic effect of a polysaccharide from Schisandra sphenanthera in rats with type 2 diabetes
23. Huang-Lian-Jie-Du-Tang Supplemented with Schisandra chinensis Baill. and Polygonatum odoratum Druce Improved Glucose Tolerance by Potentiating Insulinotropic Actions in Islets in 90% Pancreatectomized Diabetic Rats
24. Schisandra Extracts on Blood Glucose of Diabetic Mice
25. Schisandra chinensis fruit modulates the gut microbiota composition in association with metabolic markers in obese women: a randomized, double-blind placebo-controlled study
26. Anti-obesity effect of Schisandra chinensis in 3T3-L1 cells and high fat diet-induced obese rats
27. Schisandra chinensis berry extract protects against steatosis by inhibiting histone acetylation in oleic acid–treated HepG2 cells and in the livers of diet-induced obese mice
28. Schisandra chinensis Prevents Hepatic Lipid Peroxidation and Oxidative Stress in Rats Subjected to Heat Environmental Stress
29. Ameliorative Effects of 5-Hydroxymethyl-2-furfural (5-HMF) from Schisandra chinensis on Alcoholic Liver Oxidative Injury in Mice
30. Schisandra Lignan Extract Protects against Carbon Tetrachloride-Induced Liver Injury in Mice by Inhibiting Oxidative Stress and Regulating the NF-κB and JNK Signaling Pathways

Polyrhachis
“HERB OF KINGS” Dramatic Increase in Strength & Power, Speeds Workout Recovery

1. Analgesic and Anti-inflammatory Activities of Total Extract and Individual Fractions of Chinese Medicinal Ants Polyrhachis lamellidens
2. Nutritional composition of Polyrhachis vicina Roger(Edible Chinese black ant)
3. Constituents from the edible Chinese black ants (Polyrhachis dives) showing protective effect on rat mesangial cells and anti-inflammatory activity
4. Dopamine derivatives from the insect Polyrhachis dives as inhibitors of ROCK1/2 and stimulators of neural stem cell proliferation

Red Asparagus Root
“THE FLYING HERB” Elevates Mood, Promotes Deep Sleep, Lung Tonic – Increases the Lung’s Ability to Extract Qi (life force) from Air

1. Enzyme-treated Asparagus officinalis Extract Shows Neuroprotective Effects and Attenuates Cognitive Impairment in Senescence-accelerated Mice
2. In vitro antioxidant and antitumor activities of polysaccharides extracted from Asparagus officinalis
3. Asparagus officinalis extract controls blood glucose by improving insulin secretion and β-cell function in streptozotocin-induced type 2 diabetic rats
4. T-DNA organization in tumor cultures and transgenic plants of the monocotyledon Asparagus officinalis
5. Evaluation of drying technologies for retention of physical quality and antioxidants in asparagus (Asparagus officinalis, L.)
6. The aqueous extract of Asparagus officinalis L. by‐product exerts hypoglycaemic activity in streptozotocin‐induced diabetic rats
7. Hypolipidaemic and hepatoprotective effects of ethanolic and aqueous extracts from Asparagus officinalis L. by‐products in mice fed a high‐fat diet
8. Asparagus adscendens (Shweta musali) stimulates insulin secretion, insulin action and inhibits starch digestion
9. Insulin secretory actions of extracts of Asparagus racemosus root in perfused pancreas, isolated islets and clonal pancreatic β-cells
10. Antihyperglycaemic activity of Asparagus racemosus roots is partly mediated by inhibition of carbohydrate digestion and absorption, and enhancement of cellular insulin action
11. Enzyme-treated Asparagus Extract (ETAS) Enhances Memory in Normal Rats and Induces Neurite-outgrowth in PC12 Cells
12. Effects of Temperature on Longevity, Reproduction, and Development of the Asparagus Aphid (Homoptera: Aphididae) and the Parasitoid, Diaeretiella rapae (Hymenoptera: Braconidae)
13. Therapeutic effect of ethyl acetate extract from Asparagus cochinchinensis on phthalic anhydride-induced skin inflammation
14. Anti-nociceptive and anti-inflammatory effects of methanolic extract of Asparagus pubescens root in rodents
15. Saponin-enriched extract of Asparagus cochinchinensis alleviates airway inflammation and remodeling in ovalbumin-induced asthma model
16. Effect of Asparagus‐P® on cell metabolism of cultured kidney and inflammation‐mediating cells
17. Neuroprotective Activity of Asparagus racemosus Linn. Against Ethanol-Induced Cognitive Impairment and Oxidative Stress in Rats Brain: Auspicious for Controlling the Risk of Alzheimer’s Disease
18. Protective effects of Asparagusracemosus on oxidative damage in isoniazid-induced hepatotoxic rats: an in vivo study
19. Hypoglycemic, antioxidant and hypolipidemic activity of Asparagus racemosus on streptozotocin-induced diabetic in rats
20. Action of Asparagus racemosus Against Streptozotocin-Induced Oxidative Stress
21. Hypolipidemic and antioxidant activities of Asparagus racemosus in hypercholesteremic rats
22. Effect of methanolic extract of Asparagus racemosus Willd. on lipopolysaccharide induced-oxidative stress in rats
23. LC–ESI–MS/MS analysis of Asparagus racemosus Willd. roots and its protective effects against t-BHP induced oxidative stress in rats
24. Effect of Asparagus racemosus on sexual dysfunction in hyperglycemic male rats
25. Enzyme‐Treated Asparagus Extract Promotes Expression of Heat Shock Protein and Exerts Antistress Effects
26. Cytosolic acidification and γ-aminobutyric acid synthesis during the oxidative burst in isolated Asparagus sprengeri mesophyll cells
27. Ameliorative effect of Asparagus racemosus root extract against pentylenetetrazol-induced kindling and associated depression and memory deficit
28. Evaluation of Anxiolytic-Like Effect of Aqueous Extract of Asparagus Stem in Mice
29. Anti-neuroinflammatory constituents from Asparagus cochinchinensis
30. The New Phytoformula Containing Morus alba, Schizandra sinensis and Asparagus cochinchinensis Inhibits Lung Inflammation in vitro and in vivo

Tribulus
Enhances Mood, Protects Urinary Tract, Increases Sperm Count, Restores Vigor, Vitality & Stamina

1. Antioxidant Activities and Anti-tyrosinase Activity of Tribulus terrestris
2. Pilot Study on the Effect of Botanical Medicine (Tribulus terrestris) on Serum Testosterone Level and Erectile Function in Aging Males With Partial Androgen Deficiency (PADAM)
3. Evaluating the efficacy in improving male sexual function with a new natural compound made of Tribulus Terrestris, Biovis and Alga Ecklonia Cava and its synergic anti-aging action
4. Hypoglycemic Effect of Saponin from Tribulus terrestris
5. [The inhibitory effect of saponins from Tribulus terrestris on Bcap-37 breast cancer cell line in vitro].
6. Aqueous extract of Tribulus terrestris Linn induces cell growth arrest and apoptosis by down-regulating NF-κB signaling in liver cancer cells
7. Saponins from Tribulus terrestris L. Are Less Toxic for Normal Human Fibroblasts than for Many Cancer Lines: Influence on Apoptosis and Proliferation
8. Terrestrosin D, a Steroidal Saponin from Tribulus terrestris L., Inhibits Growth and Angiogenesis of Human Prostate Cancer in vitro and in vivo
9. Chemopreventive potential of Tribulus terrestris against 7,12- dimethylbenz (a) anthracene induced skin papillomagenesis in mice.
10. [Investigation on inhibitory and apoptosis-inducing effects of saponins from Tribulus terrestris on hepatoma cell line BEL-7402].
11. Cytotoxic and antitumor effects of Tribulus terrestrisL fruit methanolic extract
12. Changes in gene expression of CXCR4, CCR7 and BCL2 after treatment of breast cancer cells with saponin extract from Tribulus terrestris
13. In-Silico Molecular Docking Analysis of Cancer Biomarkers with Bioactive Compounds of Tribulus terrestris
14. The Protective Effect of Tribulus terrestris in Diabetes
15. Efficacy of Tribulus Terrestris Extract on the Serum Glucose and Lipids of Women with Diabetes Mellitus
16. Hypoglycemic and hypolipidemic effects of alcoholic extract of Tribulus alatus in streptozotocin-induced diabetic rats: A comparative study with T. terrestris (Caltrop)
17. Efficacy of the Hydroalcoholic Extract of Tribulus terrestris on the Serum Glucose and Lipid Profile of Women With Diabetes Mellitus: A Double-Blind Randomized Placebo-Controlled Clinical Trial
18. ANTIHYPERLIPIDEMIC POTENTIAL OF FRUITS OF TRIBULUS TERRESTRIS LINN
19. Protective effect of an aphrodisiac herb Tribulus terrestris Linn on cadmium-induced testicular damage
20. Anti-hyperglycaemic Activity of Tribulus terrestris L Aerial Part Extract in Glucose-loaded Normal Rabbits
21. Proteomic analysis reveals the renoprotective effect of Tribulus terrestris against obesity-related glomerulopathy in rats
22. ATILIPIDEMIC ACTIVITY OF CISSUSQUADRAGULARIS AD TRIBULUS TERRESTRIS O OBESITY I HIGH FAT FED RATS
23. EFFECTS OF SAPONINS FROM TRIBULUS TERRESTRIS L. ON INSULIN RESISTANCE AND HYPERLIPIDEMIA IN THE DIET-INDUCED OBESE RATS
24. ANTI-INFLAMMATORY AND ANTIMICROBIAL ACTIVITIES OF METHANOLIC EXTRACT OF TRIBULUS TERRESTRIS LINN PLANT
25. Anti-inflammatory activity of Tribulus terrestris in RAW264.7 Cells (54.2)
26. N‑trans‑ρ‑caffeoyl tyramine isolated from Tribulus terrestris exerts anti‑inflammatory effects in lipopolysaccharide‑stimulated RAW 264.7 cells
27. Tribulus terrestris ameliorates metronidazole-induced spermatogenic inhibition and testicular oxidative stress in the laboratory mouse
28. Standardized Aqueous Tribulus terristris (Nerunjil) Extract Attenuates Hyperalgesia in Experimentally Induced Diabetic Neuropathic Pain Model: Role of Oxidative Stress and Inflammatory Mediators
29. [Mechanisms of gross saponins of Tribulus terrestris via activating PKCepsilon against myocardial apoptosis induced by oxidative stress].
30. Protective effect of Tribulus terrestris L. fruit aqueous extracton lipid profile and oxidative stress in isoproterenol induced myocardial necrosis in male albino Wistar rats

Tongkat Ali
​”MALAYSIAN GINSENG” Normalizes Blood Sugar, Reduces Cortisol, Stabilizes Hormones, Builds Deep Strength

1. Eurycoma longifolia Jack (Tongkat Ali) induced c-Fos Expression in Sensory and Motor Neurons of the Rat Brain Nervous System.
2. Effect of Tongkat Ali on stress hormones and psychological mood state in moderately stressed subjects
3. Enhancement Effects of Tongkat Ali (Eurycoma longifolia) Supplementation on Performance Functions Following Strength Training in Middle-Aged Women
4. Effect of Eurycoma longifolia (Tongkat Ali) on the prostate cancer cell line LNCaP
5. Cytotoxic effects of the root extracts of Eurycoma longifolia Jack
6. Cytotoxic and Antimalarial β-Carboline Alkaloids from the Roots of Eurycoma longifolia
7. Anti-Tumor Activity of Eurycoma longifolia Root Extracts against K-562 Cell Line: In Vitro and In Vivo Study
8. Eurycomanone suppresses expression of lung cancer cell tumor markers, prohibitin, annexin 1 and endoplasmic reticulum protein 28
9. The In Vitro and In Vivo Anti-Cancer Activities of a Standardized Quassinoids Composition from Eurycoma longifolia on LNCaP Human Prostate Cancer Cells
10. Eurycomanone and Eurycomanol from Eurycoma longifolia Jack as Regulators of Signaling Pathways Involved in Proliferation, Cell Death and Inflammation
11. Eurycomanone Induces Apoptosis through the Up-Regulation of p53 in Human Cervical Carcinoma Cells
12. 7‐Methoxy‐(9H‐β‐Carbolin‐1‐il)‐(E)‐1‐Propenoic Acid, a β‐Carboline Alkaloid From Eurycoma longifolia, Exhibits Anti‐Inflammatory Effects by Activating the Nrf2/Heme Oxygenase‐1 Pathway
13. A new anti-inflammatory β-carboline alkaloid from the hairy-root cultures of Eurycoma longifolia
14. Antiinflammatory and analgesic effects of Eurycoma longifolia extracts
15. Induction of Apoptosis by Eurycoma longifolia Jack Extracts
16. Eurycoma longifolia: Medicinal Plant in the Prevention and Treatment of Male Osteoporosis due to Androgen Deficiency
17. Eurycoma longifolia as a potential alternative to testosterone for the treatment of osteoporosis: Exploring time-mannered proliferative, differentiative and morphogenic modulation in osteoblasts
18. Antioxidant and tyrosinase inhibition activities of Eurycoma longifolia and Swietenia macrophylla
19. In vitro Anti-Toxoplasma gondii Activity of Root Extract/Fractions of Eurycoma longifolia Jack
20. Chapter 63 – Human Performance and Sports Applications of Tongkat Ali (Eurycoma longifolia)

Cistanche
​DESERT GINSENG “THE STALK ENLARGER” Increases Vitality, Anti Aging, Builds Deep Strength, Promotes Healthy Colon Function

1. Effect of glycosides of Cistanche on the expression of mitochondrial precursor protein and keratin type II cytoskeletal 6A in a rat model of vascular dementia
2. Cistanche tubulosa phenylethanoid glycosides induce apoptosis in H22 hepatocellular carcinoma cells through both extrinsic and intrinsic signaling pathways
3. Cistanche tubulosa phenylethanoid glycosides induce apoptosis in Eca‑109 cells via the mitochondria‑dependent pathway
4. [Research on the effect of phenylethanoid glycosides (PEG) of the Cistanche deserticola on anti-aging in aged mice induced by D-galactose].
5. Effect of Cistanche tubulosa (Scheuk) Whight acteoside on telomerase activity and immunity of aging mice
6. The change of functions and hypermicro-instructure in lung in experimental aging mice and effect of cistanche desertica polysacchrides on the change
7. Desertliving cistanche anti-aging action:A comparative study
8. Studies on the sedative effect of Cistanche deserticola
9. Effect of Polysaccharides of Cistanche deserticola on Immune Cells and Telomerase Activity in Aging Mice
10. Effects of cistanche desertica polysacchrides on the constitution of protein and anti-oxidative capacity of lune in aging mice
11. Extracts of Cistanche deserticola Can Antagonize Immunosenescence and Extend Life Span in Senescence-Accelerated Mouse Prone 8 (SAM-P8) Mice
12. Advances in Research of Chemical Constituents and Medicinal Activity of Cistanche
13. Inhibitory Effect of Acteoside Isolated from Cistanche tubulosa on Chemical Mediator Release and Inflammatory Cytokine Production by RBL-2H3 and KU812 Cells
14. The effects of glycosides of cistanche on learning and memory in β-amyloid peptide induced Alzheimers disease in mice and its possible mechanism
15. Antioxidative Effects of Phenylethanoids from Cistanche deserticola
16. Reduction of Inflammatory Hyperplasia in the Intestine in Colon Cancer‐prone Mice by Water‐extract of Cistanche deserticola
17. Anti-hyperglycemic and hypolipidemic effects of Cistanche tubulosa in type 2 diabetic db/db mice
18. Reversal by aqueous extracts of Cistanche tubulosa from behavioral deficits in Alzheimer’s disease-like rat model: relevance for amyloid deposition and central neurotransmitter function
19. An Open-Label, Nonplacebo-Controlled Study on Cistanche tubulosa Glycoside Capsules (Memoregain®) for Treating Moderate Alzheimer’s Disease
20. Effect of glycosides of cistanche on learning and memory in Alzheimer′s disease mice and its mechanism
21. The Antidepressant and Cognitive Improvement Activities of the Traditional Chinese Herb Cistanche
22. Protective effects of glycosides of cistanche on behaviors and memory impairment mice induced by aluminum trichloride
23. Phenylethanoid glycosides with anti-inflammatory activities from the stems of Cistanche deserticola cultured in Tarim desert
24. Anti-nociceptive and anti-inflammatory activity caused by Cistanche deserticola in rodents
25. Synergistic anti-inflammatory effects of Laminaria japonica fucoidan and Cistanche tubulosa extract
26. Chemical constituents and in vitro anti-inflammatory activity of Cistanche violacea Desf. (Orobanchaceae) extract
27. Anti-inflammatory iridoids from the stems of Cistanche deserticola cultured in Tarim Desert
28. Experiment Study of Desertliving Cistanche Polysaccharides on Regulated Haematogenesis in Bone Marrow Depressed Anemia Mice
29. Antidepressant-Like Effects of Cistanche tubulosa Extract on Chronic Unpredictable Stress Rats Through Restoration of Gut Microbiota Homeostasis
30. An Open-Label, Non placebo-Controlled Study on Cistanche tubulosa Glycoside Capsules (Memoregain1) for Treating Moderate Alzheimer’s Disease

Lion’s Mane Mushroom
Super Brain & Memory Booster, Stimulates Nerve Growth, Boosts Intelligence & Concentration

1. Neuroregenerative Potential of Lion’s Mane Mushroom, Hericium erinaceus (Bull.: Fr.) Pers. (Higher Basidiomycetes), in the Treatment of Peripheral Nerve Injury (Review)
2. Erinacine A-Enriched Hericium erinaceus Mycelium Produces Antidepressant-Like Effects through Modulating BDNF/PI3K/Akt/GSK-3β Signaling in Mice
3. A comprehensive review of the therapeutic effects of Hericium erinaceus in neurodegenerative disease
4. LION’S MANE MUSHROOM, HERICIUM ERINACEUS -NATURAL FOOD FOR THE NEURONS AND MEMORY
5. Hericium erinaceus Improves Mood and Sleep Disorders in Patients Affected by Overweight or Obesity: Could Circulating Pro-BDNF and BDNF Be Potential Biomarkers?
6. Erinacine A-enriched Hericium erinaceus mycelium ameliorates Alzheimer’s disease-related pathologies in APPswe/PS1dE9 transgenic mice
7. Antihyperglycemic and antihyperlipidemic activities of aqueous extract of Hericium erinaceus in experimental diabetic rats
8. The Neuroprotective Properties of Hericium erinaceus in Glutamate-Damaged Differentiated PC12 Cells and an Alzheimer’s Disease Mouse Model
9. Antiageing Effect of Hericium erinaceus Polysaccharides
10. Antioxidant and hepatoprotective potential of endo-polysaccharides from Hericium erinaceus grown on tofu whey
11. Neurotrophic Properties of the Lion’s Mane Medicinal Mushroom, Hericium erinaceus (Higher Basidiomycetes) from Malaysia
12. Anticancer potential of Hericium erinaceus extracts against human gastrointestinal cancers
13. Hericium erinaceus enhances doxorubicin-induced apoptosis in human hepatocellular carcinoma cells
14. Hericium erinaceus (Lion’s Mane) Mushroom Extracts Inhibit Metastasis of Cancer Cells to the Lung in CT-26 Colon Cancer-Tansplanted Mice
15. Antitumor and immunoenhancing activities of polysaccharide from culture broth of Hericium spp.
16. A new cerebroside from the fruiting bodies of Hericium erinaceus and its applicability to cancer treatment
17. Hericium erinaceus suppresses LPS-induced pro-inflammation gene activation in RAW264.7 macrophages
18. Protective Effect of Ethanol Extracts of Hericium erinaceus on Alloxan-Induced Diabetic Neuropathic Pain in Rats
19. Antihyperglycaemic and organic protective effects on pancreas, liver and kidney by polysaccharides from Hericium erinaceus SG-02 in streptozotocin-induced diabetic mice
20. Hypoglycemic Effect of the Transformation Products from the Extract of Ginkgo biloba Leaf by Hericium erinaceus
21. Lactobacillus fermentum HP3–Mediated Fermented Hericium erinaceus Juice as a Health Promoting Food Supplement to Manage Diabetes Mellitus
22. Evaluation of the Antioxidant Activity and Anti-Inflammatory Effect of Hericium erinaceus Water Extracts
23. Extracts from Hericium erinaceus relieve inflammatory bowel disease by regulating immunity and gut microbiota
24. Polysaccharide of Hericium erinaceus attenuates colitis in C57BL/6 mice via regulation of oxidative stress, inflammation-related signaling pathways and modulating the composition of the gut microbiota
25. Evaluation of in vivo antioxidant activity of Hericium erinaceus polysaccharides
26. A unique polysaccharide purified from Hericium erinaceus mycelium prevents oxidative stress induced by H2O2 in human gastric mucosa epithelium cell
27. Hericium erinaceus promote proliferation and expression of neurotrophic factors in global cerebral ischemia
28. The Anti-inflammation Effects of Ergosterol from Hericium erinaceus on LPS-induced in RAW 264.7 cells
29. Structure of polysaccharides from the fruiting body of Hericium erinaceus Pers
30. Effect of Hericium erinaceus Mycelia Supplementation on the Oxidative Stress and Inflammation Processes Stimulated by LPS and Their Mechanisms in BALB/C Mice

Deer Velvet Antler
Increases Energy, Endurance, Stamina, Muscle Growth & Overall Vitality, Tonifies All Three Treasures,

1. First Evidence that Sika Deer (Cervus nippon) Velvet Antler Extract Suppresses Migration of Human Prostate Cancer Cells
2. Purification and partial characterization of anti-inflammatory peptide from pilose antler of Cervus nippon Temminck.
3. Immunomodulatory effects of a 3.2 kDa polypeptide from velvet antler of Cervus nippon Temminck
4. Primary mammary carcinoma in a Sika deer (Cervus Nippon) with a coexisting intestinal adenocarcinoma
5. Purification and identification of anti-inflammatory peptides derived from simulated gastrointestinal digests of velvet antler protein (Cervus elaphus Linnaeus)
6. Anti-hyperglycemic and Anti-aging Effects of Deer Antler Velvet Extract on Diabetic Mice Induced by Alloxan
7. Effect of Sika Deer (Cervus nippon) Velvet Antler on Prostate-specific Antigen Levels and Migration of LNCaP Human Prostate Cancer Cells
8. Composition of Biologically Active Substances and Antioxidant Activity of New Zealand Deer Velvet Antler Extracts
9. The immune-enhancing activity of Cervus nippon mantchuricus extract (NGE) in RAW264.7 macrophage cells and immunosuppressed mice
10. Effect of Sika Deer (Cervus nippon) Velvet Antler Extract on the Reversal of Epithelial-Mesenchymal Transition-related Genes in Prostate Xenograft Tumors
11. cDNA Library Construction from Antler Cartilage of the Red Deer (Cervus elaphus) and Cloning Insulin-like Growth Factor II Gene
12. Detection and quantitation of insulin-like growth factor-1 in velvet antler by an enzyme-linked immunosorbent assay
13. Effcets of Insulin-Like Growth Factor 1 on the Proliferation Organic Center Stem Cells at 30 days Growing Period of Antler in Vitro
14. Effcets of Insulin-Like Growth Factor 1 on the Proliferation at Different Generation of Antler Organic Center Cells
15. The Protective Effect of Sika Deer Antler Protein on Gentamicin-Induced Nephrotoxicity in Vitro and in Vivo
16. Study on the anti-inflammation and analgesic effects of Sika antlerbase extract
17. Neuroprotective Action of Deer Bone Extract Against Glutamate or Aβ1–42-Induced Oxidative Stress in Mouse Hippocampal Cells
18. Protective effects of Cervus nippon Temminck velvet antler polypeptides against MPP+‑induced cytotoxicity in SH‑SY5Y neuroblastoma cells
19. Antioxidant Activity of Aqueous Extract Fractions of Velvet Antler (Cervus elaphus Linnaeus)
20. Effects of deer velvet extract from Formosan sika deer on the embryonic development and anti-oxidative enzymes mRNA expression in mouse embryos

He Shou Wu
Promotes Longevity, Improves Fertility, Historically Revered to Slow Gray Hair, Provides Deep Primordial Energy, mTOR inhibitor

1. Novel compound from Polygonum multiflorum inhibits inflammatory response in LPS-stimulated microglia by upregulating AMPK/Nrf2 pathways
2. Hexane extracts of Polygonum multiflorum improve tissue and functional outcome following focal cerebral ischemia in mice
3. Hypoglycemic effects of stilbene glycoside from Polygonum multiflorum in type 2 diabetes and its mechanism of action
4. Emodin from Polygonum multiflorum ameliorates oxidative toxicity in HT22 cells and deficits in photothrombotic ischemia
5. Protective Effects and Mechanism of Polygonum multiflorum Thunb.Extract on Nigrostriatal Dopaminergic Neuron Lesion Induced by Paraquat
6. Study on the anti-aging effects of radix polygonum multiflorum
7. Purification, antioxidant activity and antiglycation of polysaccharides from Polygonum multiflorum Thunb
8. TSG (2,3,5,4′-Tetrahydroxystilbene-2-O-β-D-glucoside) from the Chinese Herb Polygonum multiflorum Increases Life Span and Stress Resistance of Caenorhabditis elegans
9. Antioxidant activities of Polygonum multiflorum Thunb., in vivo and in vitro
10. [Effect of compound Polygonum multiflorum extract on Alzheimer’s disease].
11. In vitro Antioxidant Activities of Maillard Reaction Products Produced in the Steaming Process of Polygonum multiflorum Root
12. Mechanistic Studies on the Use of Polygonum multiflorum for the Treatment of Hair Graying
13. Topical application of Polygonum multiflorum extract induces hair growth of resting hair follicles through upregulating Shh and β-catenin expression in C57BL/6 mice
14. Anti-proliferative effect of an extract of the root of Polygonum multiflorum Thunb. on MCF-7 human breast cancer cells and the possible mechanisms
15. Hepatoprotection of emodin and Polygonum multiflorum against CCl4-induced liver injury
16. Ultrasonic-assisted extraction, structure and antitumor activity of polysaccharide from Polygonum multiflorum
17. Structural, physicochemical, antioxidant and antitumor property of an acidic polysaccharide from Polygonum multiflorum
18. Evaluation of Anti-Oxidant Capacity of Root of Scutellaria baicalensis Georgi, in Comparison with Roots of Polygonum multiflorum Thunb and Panax ginseng CA Meyer
19. Effect of polygonum multiflorum on the fluidity of the mitochondria membrane and activity of COX in the hippocampus of rats with Abeta 1-40-induced Alzheimer’s disease.
20. Effect of polygonum multiflorum thumb on apoptosis of hippocampal neurons induced by Aβ
21. Anti-inflammatory effect of Polygonum multiflorum extraction in activated RAW 264.7 cells with lipopolysaccharide
22. Anti-inflammatory Effect of MeOH Extracts of the Stem of Polygonum multiflorum in LPS-stimulated Mouse Peritoneal Macrophages
23. Anti-inflammatory effects of novel polygonum multiflorum compound via inhibiting NF-κB/MAPK and upregulating the Nrf2 pathways in LPS-stimulated microglia
24. Antioxidant activity of stilbene glycoside from Polygonum multiflorum Thunb in vivo
25. An extract of Polygonum multiflorum protects against free radical damage induced by ultraviolet B irradiation of the skin
26. Hepatoprotective Activity of Fresh Polygonum Multiflorum Against HEP G2 Hepatocarcinoma Cell Proliferation
27. STILBENE GLYCOSIDES FROM THE ROOTS OF POLYGONUM MULTIFLORUM THUNB AND THEIR IN VITRO ANTIOXIDANT ACTIVITIES
28. Effects of Polygonum Multiflorum Thumb on Patients with Vascular Dementia
29. Preliminary Study on the Anti-inflammatory Effect of Polygonum Multiflorum
30. Acute Hepatitis Due to Shen-Min: A Herbal Product Derived From Polygonum multiflorum

Dendrobium
“THE BEAUTY HERB” Makes Skin Moist, Radiant & Glowing, Aids Digestion, Lowers Blood Sugar, Improves Eyesight

1. Effects of Rich-Polyphenols Extract of Dendrobium loddigesii on Anti-Diabetic, Anti-Inflammatory, Anti-Oxidant, and Gut Microbiota Modulation in db/db Mice
2. Isoviolanthin Extracted from Dendrobium officinale Reverses TGF-β1-Mediated Epithelial–Mesenchymal Transition in Hepatocellular Carcinoma Cells via Deactivating the TGF-β/Smad and PI3K/Akt/mTOR Signaling Pathways
3. A bibenzyl from Dendrobium ellipsophyllum induces apoptosis in human lung cancer cells
4. Inhibitory effect of different Dendrobium species on LPS-induced inflammation in macrophages via suppression of MAPK pathways
5. Effect of Dendrobium officinale on D-galactose-induced aging mice
6. Dendrobium chysotoxum extract and its cosmetic use as an anti-aging agent
7. Protective roles and mechanisms of polysaccharides from Dendrobium officinal on natural aging-induced premature ovarian failure
8. STRUCTURAL CHARACTERIZATION AND ANTI‐GLYCATION ACTIVITY IN VITRO OF A WATER‐SOLUBLE POLYSACCHARIDE FROM DENDROBIUM HUOSHANENSE
9. Anti-osmotic and antioxidant activities of gigantol from Dendrobium aurantiacum var. denneanum against cataractogenesis in galactosemic rats
10. Antioxidant and Anti-hyperglycemic Activity of Polysaccharide Isolated from Dendrobium chrysotoxum Lindl
11. Effect of sound wave stress on antioxidant enzyme activities and lipid peroxidation of Dendrobium candidum
12. Dendrobium alkaloids prevent Aβ25–35-induced neuronal and synaptic loss via promoting neurotrophic factors expression in mice
13. Effect of Water Extracts from Dendrobium huoshanense on Proliferation and Apoptosis of Human Laryngeal Carcinoma Hep-2 Cells and Relevant Mechanism
14. Gigantol, a Bibenzyl from Dendrobium draconis, Inhibits the Migratory Behavior of Non-Small Cell Lung Cancer Cells
15. Denbinobin, a phenanthrene from dendrobium nobile, inhibits invasion and induces apoptosis in SNU-484 human gastric cancer cells
16. A Bibenzyl from Dendrobium ellipsophyllum Inhibits Epithelial-to-Mesenchymal Transition and Sensitizes Lung Cancer Cells to Anoikis
17. Anti-metastatic Activities of Bibenzyls from Dendrobium pulchellum
18. Anti-metastatic Activities of Bibenzyls from Dendrobium pulchellum
19. Denbinobin, a Phenanthrene from Dendrobium nobile, Impairs Prostate Cancer Migration by Inhibiting Rac1 Activity
20. A bibenzyl from Dendrobium ellipsophyllum inhibits migration in lung cancer cells
21. Study on Antioxidant Activity of Polysaccharides from Dendrobium Species
22. Cancer Stem Cell–Suppressing Activity of Chrysotoxine, a Bibenzyl from Dendrobium pulchellum
23. Cypripedin, a phenanthrenequinone from Dendrobium densiflorum, sensitizes non-small cell lung cancer H460 cells to cisplatin-mediated apoptosis
24. Dendrobium candidum inhibits MCF-7 cells proliferation by inducing cell cycle arrest at G2/M phase and regulating key biomarkers
25. Comparison of antitumor activities of different polysaccharide fractions from the stems of Dendrobium nobile Lindl
26. Studies on Antioxidant Activity of Bibenzyls and Phenolic Components from Dendrobium nobile
27. Dendrobium officinale polysaccharide attenuates type 2 diabetes mellitus via the regulation of PI3K/Akt-mediated glycogen synthesis and glucose metabolism
28. Gene Expression and Microarray Investigation of Dendrobium Mixture as Progressive Therapy for the Treatment of Type 2 Diabetes Mellitus
29. [Effect of dendrobium mixture on hypoglycemic and the apoptosis of islet in rats with type 2 diabetic mellitus].
30. Dendrobium Compound in Treating 90 Cases of Type 2 Diabetes Mellitus

Eipemidius
​INCREASES NITRIC OXIDE Phenomenal for Cardiovascular System, Balances Hormones, Releives Sore Joints, Skeletal Health

1. Epimedium koreanum Ameliorates Oxidative Stress-Mediated Liver Injury by Activating Nuclear Factor Erythroid 2-Related Factor 2
2. The antioxidant activities effect of neutral and acidic polysaccharides from Epimedium acuminatum Franch. on Caenorhabditis elegans
3. Supplementation of licorice root and epimedium in a control or high fat diet and their effects on a preclinical metastatic breast cancer model
4. Metabonomic characterization of aging and investigation on the anti-aging effects of total flavones of Epimedium
5. [Effect of Epimedium flavonoids in retarding aging of C. elegans].
6. Characteristics of lymphocyte nuclear factor-κB signal transduction kinase expression in aging process and regulatory effect of epimedium flavonoids
7. [Effect of wolfberry fruit and epimedium on DNA synthesis of the aging-youth 2BS fusion cells].
8. [Effect and mechanism of Epimedium flavanoids for aging retardation from viewpoint of transcriptomics and metabonomics].
9. [Study on changes of protein phosphorylation of p65, IkappaBalpha and IkappaBepsilon in lymphocytes of rats in progress of aging and interventional effect of Epimedium flavonoids].
10. THE ANTI-AGING AND IMMUNOMODULATING EFFECTS OF CHINESE HERBAL DRUGS EPIMEDIUM(YINYANGHUO)AND POLYGONUM(HESHOUWU)
11. Effects of total flavones of Epimedium brevicornu Maxim on testis diseases in D-galactose-induced aging rats.
12. Total flavonoids of Epimedium attenuate aging-related inflammation in rat brain by inhibiting MAPK/NF-κB signaling pathway
13. New Estrogenic Prenylflavone from Epimedium brevicornum Inhibits the Growth of Breast Cancer Cells
14. Selective Estrogen Receptor Modulator Effects of Epimedium Extracts on Breast Cancer and Uterine Growth in Nude Mice
15. The nutritional herb Epimedium grandiflorum inhibits the growth in a model for the Luminal A molecular subtype of breast cancer
16. EFFECT OF EPIMEDIUM FLAVONE TOTAL (EFT) ON CELLULAR AND ERYTHROCYTIC IMMUNOFUNCTION OF EHRLICH ASCITES CANCER(EAC) BEARING MICE
17. [Comparison of antioxidative and antitumor activities of six flavonoids from Epimedium koreanum].
18. Effect of Epimedium koreanum Nakai on Apoptosis in HCT116 Human Colon Cancer Cells
19. Antioxidative Effects of Extracts from Different Parts of Epimedium koreanum Nakai
20. Effects of Total Flavonoids of Epimedium on Vascular Function of Diabetic Mice
21. Effect of epimedium hypoglycemic granules on type 2 diabetes rats and its mechanism
22. Glycometabolism effects of total flavonoids from two species of Epimedium in Guizhou on the type Ⅱ diabetes
23. Effects of TFE from two species of Epimedium in Guizhou on the learning and memory abilities in dementia model rats
24. Study on Chemical Constituents of Total Flavones for Anti Senile Dementia from Epimedium Herb
25. Effect of Epimedium Flavanoids on Neuro-inflammatory Reaction in Alzheimer Disease Model Mice Induced by Lateral Ventricle Injection of β-amyloid
26. Epimedium flavonoids ameliorate experimental autoimmune encephalomyelitis in rats by modulating neuroinflammatory and neurotrophic responses
27. Epimedium Polysaccharide Alleviates Polyglutamine-Induced Neurotoxicity in Caenorhabditis elegans by Reducing Oxidative Stress
28. The anti-inflammatory effects of total flavonoids of Epimedium
29. Inhibitory Effects of Epimedium Herb on the Inflammatory Response In Vitro and In Vivo
30. The effects of epimedium polysaccharides on the immune function of immune-depressed mice

Rehmania
Blood Tonic & Purifier, Restores Adrenals & Improves Kidney Function, Relieves PMS Symptoms, Improves Circulation of Blood in Brain

1. Dried Rehmannia root protects against glutamate-induced cytotoxity to PC12 cells through energy metabolism-related pathways
2. Review of the effects of the traditional Chinese medicine Rehmannia Six Formula on diabetes mellitus and its complications
3. ER、PR are up regulated by rehmannia in aging female mice
4. Antioxidant property of an active component purified from the leaves of paraquat-tolerant Rehmannia glutinosa
5. Effects of Compound Rehmannia on Learning and Memory Abilities in Senile Dementia Mice Induced by D-galactose
6. Effect of Compound Rehmannia Recipe on Apoptosis in Parkinson’s Disease Rats
7. Molecular mechanism of Rehmannia glutinosa oligosaccharides on improvement of insulin resistance of HepG2 cell in vitro
8. Effects of 5-hydroxymethyl furfural extracted from Rehmannia glutinosa Libosch on the expression of signaling molecules relevant to learning and memory among hippocampal neurons exposed to high concentration of corticosterone
9. Antidiabetic and antioxidant effects of catalpol extracted from Rehmannia glutinosa (Di Huang) on rat diabetes induced by streptozotocin and high-fat, high-sugar feed
10. Rehmannia glutinosa polysaccharide induces toll-like receptor 4 dependent spleen dendritic cell maturation and anti-cancer immunity
11. The therapeutic effects of rehmannia oral liquid for the syndrome of heat accumulation with Yin consumption in esophagus cancer patients undergoing radiotherapy–a report of 60 cases.
12. Rehmannia glutinosa polysaccharide induced an anti-cancer effect by activating natural killer cells
13. Effects of low-molecular-weight rehmannia glutinosa polysaccharides on p53 gene expression in lewis lung cancer cells in vitro
14. Hypoglycemic activity of polysaccharide fraction from rhizome of Rehmannia glutinosa Libosch. f. hueichingensis Hsiao and the effect on carbohydrate metabolism in normal mouse liver
15. Effect of Rehmannia glutinosa oligosaccharides on learning and memory abilities in rats with focal cerebral ischemia and reperfusion injury
16. [Effect of Rehmannia glutinosa water extraction on insulin resistance and gene expression of resistin in type 2 diabetes mellitus rats].
17. The Effects of Rehmannia glutinosa on the Protein Expression Related to the Angiogenesis, Cell Survival and Inflammation
18. [Effect of Rehmannia glutinosa Libosch water extraction on gene expression of proinsulin in type 2 diabetes mellitus rats].
19. Plasma Glucose Lowering Mechanisms of Catalpol, an Active Principle from Roots of Rehmannia glutinosa, in Streptozotocin-Induced Diabetic Rats
20. Ethanol extracts of Rehmannia complex (Di Huang) containing no Corni fructus improve early diabetic nephropathy by combining suppression on the ET-ROS axis with modulate hypoglycemic effect in rats
21. Characterization of the Anti-Diabetic and Antioxidant Effects of Rehmannia Glutinosa in Streptozotocin-Induced Diabetic Wistar Rats
22. Rehmannia glutinosa (Gaertn.) DC. polysaccharide ameliorates hyperglycemia, hyperlipemia and vascular inflammation in streptozotocin-induced diabetic mice
23. Stachyose extract from Rehmannia glutinosa Libosch. to lower plasma glucose in normal and diabetic rats by oral administration
24. Rehmannia glutinosa ameliorates scopolamine-induced learning and memory impairment in rats.
25. Isoproterenol Induced Stressful Reactions in the Brain Are Characterized by Inflammation due to Activation of NADPH Oxidase and ER Stress: Attenuated by Apocynin, Rehmannia Complex and Triterpene Acids
26. Effects of compound rehmannia on Ca~(2+)-ATP enzyme in mice with SAM-P/8 Alzheimer’s disease
27. Rehmannia glutinosa reduced waist circumferences of Korean obese women possibly through modulation of gut microbiota
28. A Herbal Formula HT051, a Combination of Pueraria lobata and Rehmannia glutinosa, Prevents Postmenopausal Obesity in Ovariectomized Rats
29. Rehmannia glutinosa Suppresses Inflammatory Responses Elicited by Advanced Glycation End Products
30. Hot Water Extracted Lycium Barbarum and Rehmannia Glutinosa Inhibit Liver Inflammation and Fibrosis in Rats

​Nettle Root
Protects Prostate, Optimizes & Regulates Hormones

1. Antioxidant-Rich Fraction of Urtica dioica Mediated Rescue of Striatal Mito-Oxidative Damage in MPTP-Induced Behavioral, Cellular, and Neurochemical Alterations in Rats
2. The Neuroprotective Effects of Flaxseed Oil Supplementation on Functional Motor Recovery in a Model of Ischemic Brain Stroke: Upregulation of BDNF and GDNF
3. Urtica dioica L. inhibits proliferation and enhances cisplatin cytotoxicity in NSCLC cells via Endoplasmic Reticulum-stress mediated apoptosis
4. Nettle (Urtica dioica L.) as a source of antioxidant and anti-aging phytochemicals for cosmetic applications
5. The effect of hydro alcoholic Nettle (Urtica dioica) extracts on insulin sensitivity and some inflammatory indicators in patients with type 2 diabetes: a randomized double-blind control trial.
6. Enzyme Activities in Urtica dioica: Effects of Daylength and Leaf Age on Glutamate Dehydrogenase, Aspartate Aminotransferase and Alanine Aminotransferase
7. Neuroprotective Effects of Herbal Extract (Rosa canina, Tanacetum vulgare and Urtica dioica) on Rat Model of Sporadic Alzheimer’s Disease
8. Influence of plantation age and date of harvesting of herb on yield and chemical constitute of the nettle (Urtica dioica L.) [1996]
9. Antiproliferative Effect on Human Prostate Cancer Cells by a Stinging Nettle Root (Urtica dioica) Extract
10. Aqueous extract of urtica dioica makes significant inhibition on adenosine deaminase activity in prostate tissue from patients with prostate cancer
11. Antioxidant and Apoptotic Effects of an Aqueous Extract of Urtica dioica on the MCF-7 Human Breast Cancer Cell Line
12. Ameliorative influence of Urtica dioica L against cisplatin-induced toxicity in mice bearing Ehrlich ascites carcinoma
13. The role of Urtica dioica and Nigella sativa in the prevention of carbon tetrachloride‐induced hepatotoxicity in rats
14. Effects of Urtica dioica L. seed on lipid peroxidation, antioxidants and liver pathology in aflatoxin-induced tissue injury in rats
15. Urtica dioica dichloromethane extract induce apoptosis from intrinsic pathway on human prostate cancer cells (PC3)
16. Ameliorative effects of stinging nettle (Urtica dioica) on testosterone‐induced prostatic hyperplasia in rats
17. Effects of Urtica dioica dichloromethane extract on cell apoptosis and related gene expression in human breast cancer cell line (MDA-MB-468)
18. Urtica dioica extract suppresses miR-21 and metastasis-related genes in breast cancer
19. The Urtica dioica extract enhances sensitivity of paclitaxel drug to MDA-MB-468 breast cancer cells
20. Urtica dioica Induces Cytotoxicity in Human Prostate Carcinoma LNCaP Cells: Involvement of Oxidative Stress, Mitochondrial Depolarization and Apoptosis
21. Anti-inflammatory effect of Urtica dioica folia extract in comparison to caffeic malic acid
22. Antihyperglycemic activity of the aqueous extract of Urtica dioica
23. The Protective Activity of Urtica dioica Leaves on Blood Glucose Concentration and β-cells in Streptozotocin-Diabetic Rats
24. Hypoglycemic activity of Urtica pilulifera in streptozotocin-diabetic rats
25. The effect of hydro alcoholic nettle (Urtica dioica) extract on oxidative stress in patients with type 2 diabetes: a randomized double-blind clinical trial.
26. The effect of Urtica dioica extract on the number of astrocytes in the dentate gyrus of diabetic rats
27. Antidiabetic Effect of Hydroalcholic Urtica dioica Leaf Extract in Male Rats with Fructose-Induced Insulin Resistance
28. Antihyperglycemic and antihyperlipidemic activity of Urticadioica on type 2 diabetic model rats
29. Effect of Urtica dioica on memory dysfunction and hypoalgesia in an experimental model of diabetic neuropathy
30. Urtica dioica modulates hippocampal insulin signaling and recognition memory deficit in streptozotocin induced diabetic mice

Pine Pollen
POWERFUL SUPERFOOD, Hormone Balancer, Powder of Youth!

1. Antiaging effect of pine pollen in human diploid fibroblasts and in a mouse model induced by D-galactose
2. Pinus densiflora Sieb. et Zucc. Alleviates Lipogenesis and Oxidative Stress during Oleic Acid-Induced Steatosis in HepG2 Cells
3. Anti-inflammatory Activity and Protective Ability of Water Extract from Pinus densiflora Bark against DNA Damage
4. Seasonal and needle age-dependent changes of the endophytic mycobiota in Pinus thunbergii and Pinus densiflora needles
5. Leaf-age effects on seasonal variability in photosynthetic parameters and its relationships with leaf mass per area and leaf nitrogen concentration within a Pinus densiflora crown
6. Biomass Expansion Factors for Pinus densiflora in Relation to Ecotype and Stand Age [2005]
7. Biomass and carbon storage in an age-sequence of Japanese red pine (Pinus densiflora) forests in central Korea
8. Antioxidant, Antimutagenic, and Antitumor Effects of Pine Needles (Pinus densiflora)
9. Phenolic Phytochemicals Derived from Red Pine (Pinus densiflora) Inhibit the Invasion and Migration of SK‐Hep‐1 Human Hepatocellular Carcinoma Cells
10. Pinus densiflora leaf essential oil induces apoptosis via ROS generation and activation of caspases in YD-8 human oral cancer cells
11. Antioxidant activity and analysis of proanthocyanidins from pine (Pinus densiflora) needles
12. Selectivity of Pinus sylvestris extract and essential oil to estrogen-insensitive breast cancer cells Pinus sylvestris against cancer cells
13. Pinus densiflora needle supercritical fluid extract suppresses the expression of pro-inflammatory mediators iNOS, IL-6 and IL-1β, and activation of inflammatory STAT1 and STAT3 signaling proteins in bacterial lipopolysaccharide-challenged murine macrophages
14. Effect of dietary mugwort (Artemisia vulgaris L.) and pine needle powder (Pinus densiflora) on growth performance, serum cholesterol levels, and meat quality in broilers
15. Protective effect of volatile extract from Pinus densiflora against aflatoxin B1-induced oxidative stress in HepG2 cells
16. Effect of Pinus densiflora Extract on Blood Glucose Level, OGTT and Biochemical Parameters in Streptozotocin Induced Diabetic Rats
17. Effects of fermented pinus densiflora extracts on obesity-related pro-inflammatory cytokine levels in KK-Ay mice
18. Effects of pine pollen on learning and memory impairment and changes of monoamine oxidase and acetylcholinesterase activities of brain tissue in dementia mice model
19. Pine Pollen: Ancient Medicine for a New Millennium
20. Study on the Effect and Functional Mechanism of Pine Pollen on Reducing the Blood-fat Level of the Experimental Mice
21. Preventing effect on diet-induced obesity of water-extract from masson pine pollen on mice
22. ANTI-OBESE EFFECT OF WATER-EXTRACTS FROM MASSON PINE POLLEN IN MICE FED HIGH FAT DIET
23. Effects of Sulfated Polysaccharide from Masson Pine Pollen on Insulin Secretion and [Ca~(2+)]_i in MIN6 Cell
24. Research of Pine Pollen Balsam Pear & Mulberry Leaf Powder in Reducing Rats Blood Glucose
25. PINE POLLEN EXTRACT SUPPRESS TYPE II COLLAGEN-INDUCED ARTHRITIS IN DBA/1J MICE
26. Anti-fibrotic effects of the Masson pine pollen aqueous extract on hepatic fibrosis rat model

Mucana Pruriens
BRAIN TONIC, Promotes Strong Mental Health, Supports Positive Mood, Increases Dopamine, Prevent Parkinsons

1. Mucuna pruriens seed extract reduces oxidative stress in nigrostriatal tissue and improves neurobehavioral activity in paraquat-induced Parkinsonian mouse model
2. SYNERGISTIC NEUROPREVENTIVE EFFECT OF WITHANIASOMNIFERA ROOT POWDER AND MUCUNA PRURIENS SEEDPOWDER IN PARKINSONIC MICE MODEL
3. Phytochemical Analysis and Antioxidant Property of Leaf Extracts of Vitex doniana and Mucuna pruriens
4. Antioxidant property of Mucuna pruriens Linn
5. Mucuna pruriens reduces inducible nitric oxide synthase expression in Parkinsonian mice model
6. Cognitive Enhancing and Antioxidative Potentials of Velvet Beans (Mucuna pruriens) and Horseradish (Moringa oleifera) Seeds Extracts: A Comparative Study
7. Mucuna pruriens and Its Major Constituent L-DOPA Recover Spermatogenic Loss by Combating ROS, Loss of Mitochondrial Membrane Potential and Apoptosis
8. Therapeutic potential of Mucuna pruriens (Linn.) on ageing induced damage in dorsal nerve of the penis and its implication on erectile function: an experimental study using albino rats
9. Mucuna pruriens Protects against MPTP Intoxicated Neuroinflammation in Parkinson’s Disease through NF-κB/pAKT Signaling Pathways
10. Anti-Inflammatory, Diuretic and Antibacterial Activities of Aerial Parts of Mucuna pruriens Linn.
11. Antiproliferative effect of isolated isoquinoline alkaloid from Mucuna pruriens seeds in hepatic carcinoma cells
12. STUDIES ON IN VITRO ANTIOXIDANT ACTIVITIES OF METHANOL EXTRACT OF MUCUNA PRURIENS (FABACEAE) SEEDS
13. Studies on antioxidant activities of mucuna seed (Mucuna pruriens var utilis) extract and various non‐protein amino/imino acids through in vitro models
14. Effect of Mucuna pruriens (Linn.) on Sexual Behavior and Sperm Parameters in Streptozotocin‐Induced Diabetic Male Rat
15. Antiproliferative potential of aqueous leaf extract of Mucuna pruriens on DMBA-induced breast cancer in female albino rats
16. In vitro evaluation of Mucuna pruriens (L.) DC. antioxidant activity
17. Evaluation of Anxiolytic Effect of Chronic Administration of Mucuna Pruriens In Wistar Albino Rats
18. Dopamine mediated antidepressant effect of Mucuna pruriens seeds in various experimental models of depression
19. The effect of Momordica charantia and Mucuna pruriens in experimental diabetes and their effect on key metabolic enzymes involved in carbohydrate metabolism
20. Hypoglycemic effect of Mucuna pruriens seed extract on normal and streptozotocin-diabetic rats
21. Effect of Mucuna pruriens (Linn.) on mitochondrial dysfunction and DNA damage in epididymal sperm of streptozotocin induced diabetic rat
22. ANTIDIABETIC EVALUATION OF MUCUNA PRURIENS, LINN SEEDS
23. Effect of Mucuna pruriens (Linn.) on Oxidative Stress-Induced Structural Alteration of Corpus Cavernosum in Streptozotocin-Induced Diabetic Rat
24. Hypoglycemic and hypolipidemic activity of leaves of Mucuna pruriens in alloxan induced diabetic rats
25. Evaluation of the anti–diabetic properties of Mucuna pruriens seed extract
26. Evaluation of Effect of Ethanolic Leaf Extract of Mucuna pruriens on Blood Glucose Levels in Alloxan-Induced Diabetic Wistar Rats
27. In vitro hypoglycemic effects of Albizzia lebbeck and Mucuna pruriens
28. Hepatoprotective and in vivo antioxidant activities of the hydroethanolic leaf extract of Mucuna pruriens (Fabaceae) in antitubercular drugs and alcohol models
29. Hypoglycemic, Hematologic and Hypolipidemic Activity of Mucuna Pruriens Ethanol Leaf Extract in Alloxan Induced Diabetic Rats
30. An investigation of antioxidant and antidiabetic effect of aqueous leaf extracts of mucuna pruriens

Codonopsis
​Nourishes Vitality, Combats Stress, Super Qi Tonic, Relieves Chronic Fatigue, Promotes Mental Sharpness & Memory, Immune Booster

1. Antilipogenic and Anti-Inflammatory Activities of Codonopsis lanceolata in Mice Hepatic Tissues after Chronic Ethanol Feeding
2. Codonopsis Lanceolata Extract Prevents Hyperlipidemia and Obesity in Isocalorie Induced Obese Rats
3. Codonopsis lanceolata attenuates allergic lung inflammation by inhibiting Th2 cell activation and augmenting mitochondrial ROS dismutase (SOD2) expression
4. Bak is a key molecule in apoptosis induced by methanol extracts of Codonopsis lanceolata and Tricholoma matsutake in HSC-2 human oral cancer cells
5. The inhibitory effect of a polysaccharide from Codonopsis pilosula on tumor growth and metastasis in vitro
6. β-D-Xylopyranosyl-(1→3)-β-D-glucuronopyranosyl Echinocystic Acid Isolated from the Roots of Codonopsis lanceolata Induces Caspase-Dependent Apoptosis in Human Acute Promyelocytic Leukemia HL-60 Cells
7. Codonopsis lanceolata extract induces G0/G1 arrest and apoptosis in human colon tumor HT-29 cells – Involvement of ROS generation and polyamine depletion
8. Inhibitory effect of saponin fraction from Codonopsis lanceolata on immune cell-mediated inflammatory responses
9. Anti-Tumor Effect of Steamed Codonopsis lanceolata in H22 Tumor-Bearing Mice and Its Possible Mechanism
10. Antimutagenic and Antitumor Effects of Codonopsis lanceolata Extracts
11. Codonopsis lanceolata polysaccharide CLPS inhibits melanoma metastasis via regulating integrin signaling
12. Protective effects of an herbal formulation of Radix Astragali, Radix Codonopsis and Cortex Lycii on streptozotocin‐induced apoptosis in pancreatic β‐cells: an implication for its treatment of diabetes mellitus
13. Effect of Polysaccharides from Radix Codonopsis on Insulin Resistance in Diabetic Mice
14. Codonopsis javanica root extracts attenuate hyperinsulinemia and lipid peroxidation in fructose-fed insulin resistant rats
15. Effects of Polysaccharides Extracted from Radix Codonopsis Lanceolatae on Blood Glucose and Immune Function in Rats Diabetes with Mellitus
16. Suppression of low-density lipoprotein oxidation, vascular smooth muscle cell proliferation and migration by a herbal extract of Radix Astragali, Radix Codonopsis and Cortex Lycii
17. Effect of Selenium-Banqiao-Codonopsis-pilosula in experimental diabetic mice
18. Triterpenoid saponins and anti-inflammatory activity of Codonopsis lanceolata
19. Lancemaside A from Codonopsis lanceolata Modulates the Inflammatory Responses Mediated by Monocytes and Macrophages
20. The comparison of antioxidative and hepatoprotective activities of Codonopsis pilosula polysaccharide (CP) and sulfated CP
21. Neuroprotective Effect of Steamed and Fermented Codonopsis lanceolata
22. Improving antioxidant activity in transgenic Codonopsis lanceolata plants via overexpression of the γ-tocopherol methyltransferase (γ-tmt) gene
23. Lancemaside A isolated from Codonopsis lanceolata and its metabolite echinocystic acid ameliorate scopolamine-induced memory and learning deficits in mice
24. Dung-shen (Codonopsis pilosula) attenuated the cardiac-impaired insulin-like growth factor II receptor pathway on myocardial cells
25. Codonopsis lanceolata Extract Prevents Diet-Induced Obesity in C57BL/6 Mice
26. Antiobesity Effect of Codonopsis lanceolata in High-Calorie/High-Fat-Diet-Induced Obese Rats
27. Effects of Astragalus and Codonopsis pilosula polysaccharides on alveolar macrophage phagocytosis and inflammation in chronic obstructive pulmonary disease mice exposed to PM2.5
28. Codonopsis lanceolata Water Extract Increases Hepatic Insulin Sensitivity in Rats with Experimentally-Induced Type 2 Diabetes
29. Codonopsis Lanceolata Inhibits Adipogenesis in 3T3-L1 Cells and in High Fat Diet-Induced Obese Mice
30. Antidiabetic Effect of Codonopsis Lanceolata through the Regulation of Glucose Metabolism in C75BL/ KsJ-db/db Mice

​Eucommia
​Builds Jing, Tonifies Kidneys, Relieves Lower Back & Knee Pain Issues, Reduces High Blood Pressure

1. Neuroprotective effect of lignans extracted from Eucommia ulmoides Oliv. on glaucoma-related neurodegeneration
2. Anti-Inflammatory Activity of Iridoid and Catechol Derivatives from Eucommia ulmoides Oliver
3. Eucommia ulmoides Leaf Extract Ameliorates Steatosis Induced by High-fat Diet in Rats by Increasing Lysosomal Function
4. Eucommicin A, a β-truxinate lignan from Eucommia ulmoides, is a selective inhibitor of cancer stem cells
5. Antioxidant Activity of Extracts from Du-zhong (Eucommia ulmoides) toward Various Lipid Peroxidation Models in Vitro
6. Antioxidant actions of Du-zhong (Eucommia ulmoides oliv.) toward oxidative damage in biomolecules
7. Inhibitory effects of Du-zhong (Eucommia ulmoides Oliv.) against low-density lipoprotein oxidative modification
8. Antioxidant, Antidiabetic and Cytotoxic Effects of Eucommia ulmoides Oliv. Bark in vitro
9. Elucidation of Anti-inflammatory Potencies of Eucommia ulmoides Bark and Plantago asiatica Seeds
10. Microwave-assisted extraction and purification of chlorogenic acid from by-products of Eucommia Ulmoides Oliver and its potential anti-tumor activity
11. Antioxidative activity of water extracts from leaf, male flower, raw cortex and fruit of Eucommia ulmoides Oliv.
12. Protective effects of Eucommia ulmoides Oliv. bark and leaf on amyloid β-induced cytotoxicity
13. Neuroprotective effects of macranthoin G from Eucommia ulmoides against hydrogen peroxide-induced apoptosis in PC12 cells via inhibiting NF-κB activation
14. Soluble Epoxide Hydrolase Inhibitory and Anti-inflammatory Components from the Leaves of Eucommia ulmoides Oliver (Duzhong)
15. Antioxidant Activity Analysis and Identification of an Endophytic Fungal Strain from Eucommia ulmoides Oliv
16. Hypoglycemic effect of Du-zhong (Eucommia ulmoides Oliv.) leaves in streptozotocin-induced diabetic rats
17. Eucommia ulmoides Oliver Leaf Extract Increases Endogenous Antioxidant Activity in Type 2 Diabetic Mice
18. Hypoglycemic and hypolipidemic action of Du-zhong (Eucommia ulmoides Oliver) leaves water extract in C57BL/KsJ-db/db mice
19. [The effects of eucommia ulmoides oliv on catching action of diabetic rats and myelinated nerve fibers in penile tissues].
20. Anti-inflammatory Effects of Water Extract of Eucommia ulmoides OLIVER on the LPS-induced RAW 264.7 Cells
21. Extract from Eucommia ulmoides Oliv. ameliorates arthritis via regulation of inflammation, synoviocyte proliferation and osteoclastogenesis in vitro and in vivo
22. Effects of Aucubin Isolated from Eucommia ulmoides on UVB-induced Oxidative Stress in Human Keratinocytes HaCaT
23. Anti-obesity compounds in green leaves of Eucommia ulmoides
24. Eucommia Leaf Extract (ELE) Prevents OVX-Induced Osteoporosis and Obesity in Rats
25. Anti-obesity Effects of Eucommia ulmoides Leaves
26. Asperuloside stimulates metabolic function in rats across several organs under high-fat diet conditions, acting like the major ingredient of Eucommia leaves with anti-obesity activity
27. Du-zhong (Eucommia ulmoides Oliver) Leaf Extract Mediates Hypolipidemic Action in Hamsters Fed a High-Fat Diet
28. Preparative isolation and purification of seven main antioxidants from Eucommia ulmoides Oliv. (Du-zhong) leaves using HSCCC guided by DPPH-HPLC experiment
29. The Evaluation of Antioxidant and Anti-Inflammatory Effects of Eucommia ulmoides Flavones Using Diquat-Challenged Piglet Models
30. Neuroprotective effects of Eucommia ulmoides Oliv. Bark on amyloid beta25–35-induced learning and memory impairments in mice

Ajuga Turkestanica
Builds Rapid Muscle, Increases Strength, Dramatically Reduces Workout Recovery Time, Contains the Powerful Ecdysterone: Turkesterone

1. Antiproliferative, antimicrobial and antioxidant activities of the chemical constituents of Ajuga turkestanica
2. In vitro production of metabolism-enhancing phytoecdysteroids from Ajuga turkestanica
3. Hypoglycemic Activity of the Total Ecdysteroid Extract from Ajuga turkestanica
4. Hypoglycaemic effects of Ajuga extract in vitro and in vivo

Catuaba Bark
Mood Support, Protects Brain, Enhances Vitality, Powerful tonic or Men & Women, Relieves Depression

1. A validated higher-performance liquid chromatography method for quantification of cinchonain Ib in bark and phytopharmaceuticals of Trichilia catigua used as Catuaba
2. Potent protecting effects of Catuaba (Anemopaegma mirandum) extracts against hydroperoxide-induced cytotoxicity
3. Catuaba (Trichilia catigua) Prevents Against Oxidative Damage Induced by In Vitro Ischemia–Reperfusion in Rat Hippocampal Slices
4. Antioxidant Phenylpropanoid-Substituted Epicatechins from Trichilia catigua
5. Statistical mixture design selective extraction of compounds with antioxidant activity and total polyphenol content from Trichilia catigua
6. In vitro antioxidant activity of stem bark of Trichilia catigua Adr. Juss
7. Subchronic administration of Trichilia catigua ethyl-acetate fraction promotes antidepressant-like effects and increases hippocampal cell proliferation in mice
8. Trichilia catigua ethyl-acetate fraction protects against cognitive impairments and hippocampal cell death induced by bilateral common carotid occlusion in mice
9. Ethyl-acetate fraction of Trichilia catigua restores long-term retrograde memory and reduces oxidative stress and inflammation after global cerebral ischemia in rats
10. The exposure to Trichilia catigua (catuaba) crude extract impairs fertility of adult female rats but does not cause reproductive damage to male offspring
11. Antioxidant, anticholinesterase and antifatigue effects of Trichilia catigua (catuaba)
12. Antidepressant-like effects of Trichilia catigua (Catuaba) extract: evidence for dopaminergic-mediated mechanisms

Warnings

As with any supplement, consult your medical practitioner prior to using this product if you are pregnant, may become pregnant, breastfeeding, taking medication, other dietary supplements or have a medical condition.

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.