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KETOSIS EXPLANATION AND MTOR
March 1, 2016

THE ULTIMATE PATH TO LONGEVITY.

A TRUE LIFE OR DEATH SCENARIO.

On extended dry fasts the first few days are the roughest as the body is still optimistically holding out for food or water but once it figures out that water and food are not coming and that death is imminent if it doesn’t adapt and fast to given circumstance it switches gears into survival mode— this highly adapted state IS the magical key of dry fasting. Survival of the fittest. All weakness is eradicated. The option of supporting the diseased and parasitic is no longer viable. All non essentials are eliminated and recycled to sustain the essentials. This IS cellular renewal at the deepest level— unattainable by any other means.

A 5 DAY DRY FAST SCIENTIFIC STUDY

Background: Although there is considerable research in the field of fasting and fluid restriction, little is known about the impact of food and water deprivation (FWD) on body circumferences and vital parameters. Methods: During 5 days of FWD in 10 healthy adults, hemodynamic, metabolic, and renal parameters, such as weight, 5 circumferences at neck, waist, hip, chest at axilla, chest at nipples, and 1 new oblique hip circumference were measured daily. For each circumference, new quotients of daily circumference-to-weight decrease were calculated. The set of employed parameters quantified and monitored dieting persons’ compliance and efficacy of the method. Results: The values of blood pressure, heart rate, hemoglobin oxygen saturation, glucose, K+, Na+, Cl-, urea, creatinine, and serum osmolality proved to be stable. The mean creatinine clearance increased up to 167%. The mean daily weight decrease (1,390 ± 60 g) demonstrated the effectiveness of FWD in weight reduction. The daily decrease of all measured circumferences and the values of the corresponding circumference-to-weight decrease quotients reflected considerable volume decrease in all measured body parts per day and kg of weight loss during FWD. Conclusion: The intervention of 5 FWD days in 10 healthy adults was found to be safe, decreased weight and all measured circumferences, and improved renal function considerably.

While indeed longer duration dry fasts, 3 to 7 days and beyond, are best utilized to bring an ill or obese person back into balance—once homeostasis is restored daily dry fasting is the most effective disease preventive measure one can employ in maintaining optimal health and delaying aging.

THIS IS THE HOW AND WHY BEHIND DRY FASTING.

DAILY DRY FASTING in conjunction with anti-aging herbs and diet— the SCIENCE behind it.

For daily dry fasting which is your wisest protocol for maintaining a precision tuned body built for the long haul a 1-6 hour eating window is recommended with your highest level of activity including workout around this time as well.

In other words:

23:1, 22:2, 21:3, 20:4, 19:5 or 18:6

1st number dry, 2nd number feeding window.

RESTRICTION OF FEEDING TIME —WHY?

**It’s not what you eat so much as WHEN you eat. **

“Feeding schedule has been shown to have a signifiant impact on health and survival. In studies, time-restricted feeding had profound effects on neural, peripheral, and cardiovascular physiology and improved sleep, body weight maintenance, and delayed signs of cardiac aging, under UNCHANGED caloric intake and activity.”

SOURCE: HERE

There are 3 factors we are focusing on that promotes longevity and absence of disease:

  • AMPK ACTIVATION
  • MTOR INHIBITION
  • AUTOPHAGY

More HERE

All 3 are activated by KETOSIS* which is a rapid result of DRY FASTING. (No water or food.)

*KETONE BODIES STIMULATE CHAPERONE-MEDIATED AUTOPHAGY

“Interestingly, the increase in the concentration of circulating ketone bodies parallels the induction of CHAPERONE-MEDIATED AUTOPHAGY (CMA), which is also activated by prolonged starvation.

In these studies we have demonstrated that ketone bodies, more specifically BOH, stimulate CMA by causing the oxidation of substrates. In addition, during prolonged starvation CMA is activated because of increased lamp2a in the lysosomal membrane and increased lyhsc70 in the lysosomal lumen (9, 31). Our data indicate that ketone bodies can also stimulate CMA by affecting substrate proteins during prolonged starvation in vivo. This finding gives us further insight into the physiological importance of CMA stimulation during times of nutrient deprivation.”

SOURCE: HERE

Chaperone-mediated autophagy: roles in disease and aging

LYSOSOMES

To understand autophagy you need to understand lysosomes. Watch this brief VIDEO explaining what they are.

EXCELLENT VIDEO visually explaining the 3 types of AUTOPHAGY:

  • MACROAUTOPHAGY
  • MICRAUTOPHAGY
  • CHAPERONE-MEDIATED AUTOPHAGY

WHY NO WATER?

The ketogenic diet (KD) is traditionally introduced with an initial period of fasting and fluid restriction. *Since the 1930s it has been known that fluid restricted fasting accelerates ketosis which in turn has positive effects on preventing epilepsy.

SEE HERE

Question: If dehydration RAISES blood sugar and fasting LOWERS blood sugar….

what happens when you combine them together as in dry fasting?

ULTRA RAPID ONSET OF KETOSIS! 

(READ MORE IN THE NEXT BLOG TITLED KETOSIS)

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