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APIGENIN 200:1
February 22, 2022
HYPNOTIC : Ultimate Sleep Formula 200:1 – NEW!
February 22, 2022

VICTORIOUS : Science Based Anti Viral Formula 200:1 —NEW!

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MANDATORY FDA DISCLAIMER
ATTENTION: ZERO CLAIMS ARE MADE HERE OR ANYWHERE ON WEBSITE TO CURE ANYONE OF ANYTHING; INSTEAD WE SIMPLY PRESENT THE SCIENTIFIC STUDIES AND ALLOW THE READER TO READ, CRITICALLY THINK AND REACH THEIR OWN CONCLUSIONS. WE DO NOT ENCOURAGE ANYONE TO NOT LISTEN TO THEIR DOCTOR OR TO STOP TAKING THEIR PRESCRIBED MEDICATIONS.
PLEASE READ AND UNDERSTAND TERMS AND CONDITIONS BEFORE PURCHASING.

175 SCIENCE BASED INGREDIENTS

THE MOST COMPREHENSIVE ALL NATURAL ANTIVIRAL FORMULA EVER CREATED

Featuring: 1-Dehydrogingerdione – Zingiber Officinale (Ginger)• 3,2᾿Dihydroxyflavone (3,2᾿Dhf) & 3,4᾿Dihydroxyflavone (3,4᾿Dhf) – Trifolium Repens L. • 6-Gingerol – Zingiber Officinale (Ginger)• Acidicheteroglucan – Tremella Fuciformis • Aconitum Carmichaelii Debx • Ailanthus Altissima Stem Bark  • Allantoin – Glyoxylic Acid • Alphitonia Philippinensis Stems • Amygdalin – Semen Armeniacae Amarum • Anemarrhena Asphodeloides  • Angelica Sinensis (Oliv.) Diels • Apigenin – Celery • Arctigerin, Arctin – Burdock (Arctium Lappa) • Artemisinin – Artemisia Annua • Aspalathin – Rooibos Tea • Atractylodin ,Β-Eudesmol, Hinesol, Hydroxy-Atractylo – Rhizoma Areactylodis Lanceae • Baicalein – Scutellaria Baicalensis Georgi • Benzaldehyde – Laurus Nobilis Leaves • Berberine – Coptis Chinensis • Beta-Sitosterol – Rice Bran Oil • Betulinic Acid – Betula Platyphylla Suk Bark • Bisdemethoxycurcumin – Turmeric Rhizome • Brachyamide B – Piper Boehmeriaefolium (Miq.) C. Dc • Bulbocapnine – Corydalis Decumbens(Thunb.) • Caffeic Acid – Cimicifuga Simplex (Dc.) Wormsk. Ex Turcz.Root • Calanolide A – Calophyllum Lanigerum • Campesterol – Rapeseed Oil • Carvacrol – Oregano • Chavicine – Black Pepper • Chelidimerine – Chelidonium Majus • Chlorogenic Acid – Green Coffee Bean • Chrysin – Pinus Mon-Ticola Dougl • Cinanserin – Cinnamic Acid • Cinnamomum Cassia Presl Dried Bark • Cirsilineol – Cirsium Lineare (Thunb.) Sch. • Cirsimaritin – Rabdosia Eriocalyx • Cis-Capsaicin (Civamide) – • Colchicine – Colchicum Autumnale L. • Cordifolioside A – Viola Verecunda • Crategolic Acid – Hawthorn • Curcumin – Turmeric Root • Cycloastragenol – Astragalus Membranaceus • Cyclocurcumin – Turmeric Root • Demethoxycurcumin – Turmeric Root • Dianthus Caryophyllus Seed – Carnation • Dioscin, Diosgenin – Wild Yam （Dioscorea Oppositae Thunb）• Douchi (Semen Sojae Praepatum) – Semen Sojae Praepatum • Egcg – Green Tea • Emodin  – Rhubarb • Eriodictyol – Lemon • Eugenitin – Clove • Ferruginol – Podocarpus Ferruginea • Fisetin – Rhus Succedanea L • Flavonol Glucoside – Trichilia Connaroides Leaves • Forskolin – Coleus Forskohlii • Fructus Perillae – Perillafrutescens • Fumarophycine – Laptopyrum Reichb • Galangin – Alpinia Officinarum Hance Root • Gallic Acid – Rheumpalmatum L.Root • Genistein – Genista Tinctoria Linn Root • Glycyrrhizic Acid – Licorice Root • Gossypol – Cotton Seed • Guineensine – Piper Longum L. • Gypsum Fibrosum – Gypsum • Hawthorn Flavone – Crataegus Pinnatifida Bunge • Herba Dendrobii – Dendrobium Nobile Lindl • Herbacetin – Flaxseed • Hesperetin – Citrus Aurantium • –Hesperidin Nobiletin B-Phellandrene – Pericarpium Citri Reticulatae • Himachalol – Cupressus Funebris Endl. • Honokiol – Magnolia Officinalis • Houttuynia Cordata – Houttuynia Cordata Thunb • Hypericin Pseudohypericin Protohypericin – Forsythia Suspensa • Isochavicine – Pepper • Isoliquiritigenin – Glycyrrhiza Uralensisfisch Root • Isopiperine – Pepper • Isothymonin – Kaempferia Galanga L • Jatrorrhizine – Phellodendron Amurense Rupr. • Jujuboside A+B – Jujube • Kaempferol – Kaempferol Galanga L • Kaempferol 3-O-Robinobioside – Robinia Pseudoacacia L. • Leachianone – Morus Alba Root Bark • Lepidium Meyenii (Maca )  • Lily – Lilium Auratum • Luteoforol (A Flavan-4-Ol) – Peanut Shell • Luteolin – Peanut Shell • Lycoris Radiata – Lycoris Radiata (L’her.) Herb. • Macaranga Barteri Leaves • Maclura Cochinchinensis (Loureiro) Corner Root • Magnoflorine – Thalictrum Aquilegifolium Root • Marrubium Peregrinum L (Lamiaceae) • Meliacine – Melia Azedarach L • Mint – Mentha Haplocalyx Briq.• Morroniside,7-0-Methylmorroniside, Sweroside, Loganin, Cornus-Tannin 1,2,3 – Cornus Officinalis (Fructus Corni) • Morroniside,Cornus-Tannin 1,2,3 – Fructus Corni • Myricetin – Black Bayberry Fruit • Naringenin – Amacardi-Um Occidentale L.) • Ndoxyl-Β-Glucoside Uridine, Salicylic Acid,Daucosterol, Β-Sitostero – Radix Isatidis P.E (Satis Tinctoria L. Isatis Indigotica Fort.) • Nothofagin – Aspalathus Linearis • Oleanolic Acid – Olea Europaea L.Leaves • Olomoucine Ii – • Ophiocarpine – Corydalis Ophiocarpa Hook. F. Et Thoms • Ophiopogonin A B C D – Ophiopogon Root • Orientin – Globeflower • Oxypeucedanin Stiamasterol Β-Sitosterol Β-Daucosterin – Angelica Dahurica • Paeoniflorin – Radix Paeoniae Rubra • Patrinia Villosa Juss. – Patrinia Villosa (Thunb. ) Juss. • Peach Kernel – Emen Persicae • Pectolinarin – Linaria Vulgaris Hill Subsp. • Pelargonium Sidoides – Pelargonium Peltatum (L.) Ait. • Pentadienoylpiperidine – Pepper • Phragmitescommunis Trin – Phragmites Australis (Cav.) Trin. Ex Steud • Phyllanthus Orbicularis – Phyllanthus Orbicularis Kunth • Pinusolidic Acid – Vanillin & Malonic Acid • Piperettine – Pepper • Pipericide – Pepper • Piperine – Pepper • Piperolein B – Pepper • Poria Cocos Polysaccharide – Poria Cocos(Schw.)Wolf. • Protocatechuic Acid – Stenoloma Chusanum(L.) Ching Leaves • Protopine – Corydalis Yanhusuo W.T.Wang • Quercetin – Sophora Japonica • Quercetin-3-B-Galactoside – St. John’s Wort • Quercetin-3,7-O-Α-L-Dirhamnoside （Quercitrin） – Sabina Pingii Var. Wilsonii • Quinic Acid – Cinchona Bark • Radix Codonopsis Root • Radix Glehniae – Coasiai Giehnia Root • Radix　Platycodonis Platycodigenin, Polygalacic Acid – Platycodon Grandiflorum Root • Radix Scrophulariae Root • Reserpine – Rauvolfia Verticillata (Lour.) Baill. • Resveratrol – Polygonum Cuspidatum • Retrofractamide A – Black Pepper • Rhamnetin – Syzygium Aromaticum  • Rhizoma Atractylodis Macrocephalae Root • Rhizoma Pinelliae – Pinellia Ternata (Thunb.) Breit • Rhoifolin – Turpinia Arguya Seem Leaves • Rosmarinic Acid – Rosemary • Rupestonic Acid – Artemisia Rupestris L. • Rutin – Ruta Graveolens L. • Saikosapoins A B C D  – Bupleurum (Radix Stellariae) • Salicin – Salix Babylonical Bark • Salidroside, Rosavine, Rosin，Rosarin，Rhodiolin – Rhodiola Rosea • Samarangenin B – Limonium Bicolor (Bag.) Kuntze • Saposhnikovia Divaricata (Trucz.) Schischk Root • Savinin • Schisandrin, Deoxyschisandrin, Neoschisandrin – Schisandra Chinensis • Schizonepeta Tenusfolia Briq Dried Flower • Selaginella Moellendorfii Hieron  • Semen Lepidii Semen Descurainiae – Eruca Sativa Mill • Silibinin – Milk Thistle • Silymarin – Milk Thistle • Solanum Rantonnetii Aerial Parts Extact – Lycianthes Rantonnetii Bitter • Somniferine – Ashwagandha/Ajagandha/Kanaje • Stigmasterol – Soybean • Synephrine – Citrus Aurantium Powde • Taxillus Sutchuenensis – Taxillus Sutchuenensis (Lecomte ) Danser • Tinocordifolin – Tinospora Cordifolia • Tinocordifolioside – Tinospora Cordifolia • Tinosporide – Tinospora Cordifolia • Trichostachine – Piper Hancei Maxim • Triterpenoid Saponins – Trichosanthes Kirilowii (Mongolian Snakegourd Fruit) • Umbelliferone – Ruta Graveolens L. • Ursolic Acid – Loquat Leaf • Valinomycin – Bacterium Streptomyces • Verbascum Thapsus L – Mullein • Vicenin – Desmodium Styracifolium • Vincamine – Catharanthus Roseus （L.）G. Don • Vitex Polygama – Vitex Negundo L. Var. Cannabifolia (Sieb. Et Zucc.) Hand.-Mazz • Withaferin A – Ashwagandha • Withanolide – Ashwagandha • Withanolide B – Ashwagandha • Withanone – Ashwaganda • Wogonin – Scutellaria Baicalensis （Radix Scutellariae） • Wrinkled Gianthyssop Herb – Agastache Rugosa (Fisch. Et Mey.) O. Ktze. • Yohimbine – Yohimbe Bark

200:1 CONCENTRATION

VERY POTENT

300 1/8 tsp servings per 100g bag.

Take 1/8 -1/4 serving 2-4 times a day.

 

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ANTIVIRAL EFFECTS OF FLAVONOIDS AND POLYPHENOLS (THOUSANDS OF STUDIES – CLICK TO READ)

May Polyphenols Have a Role Against Coronavirus Infection? An Overview of the Evidence

Overall, this evidence suggests that polyphenols may exert a marked and well-demonstrated activity against coronaviruses, at least in vitro, in addition to the previously demonstrated antiviral activity in vivo. Studies available in the literature agree in establishing that the reduction of virus titer and the inhibition of nucleocapsid protein expression are their main general mechanisms of action at the base of this promising effect of polyphenols. These elucidated mechanisms are of great interest, since nowadays no effective treatments have been licensed, and the development of novel synthetic drugs against specific coronavirus molecular targets are still far from being achieved.

Antiviral effect of flavonoids on human viruses

The effect of several naturally occurring dietary flavonoids including quercetin, naringin, hesperetin, and catechin on the infectivity and replication of herpes simplex virus type 1 (HSV-1), polio-virus type 1, parainfluenza virus type 3 (Pf-3), and respiratory syncytial virus (RSV) was studied in vitro in cell culture monolayers employing the technique of viral plaque reduction. Quercetin caused a concentration-dependent reduction in the infectivity of each virus. In addition, it reduced intracellular replication of each virus when monolayers were infected and subsequently cultured in medium containing quercetin. Preincubation of tissue culture cell monolayers with quercetin did not affect the ability of the viruses to infect or replicate in the tissue culture monolayers. Hesperetin had no effect on infectivity but it reduced intracellular replication of each of the viruses. Catechin inhibited the infectivity but not the replication of RSV and HSV-1 and had negligible effects on the other viruses. Naringin had no effect on either the infectivity or the replication of any of the viruses studied. Thus, naturally occurring flavonoids possess a variable spectrum of antiviral activity against certain RNA (RSV, Pf-3, polio) and DNA (HSV-1) viruses acting to inhibit infectivity and/or replication.

Discovery of anti-2019-nCoV agents toward respiratory diseases via docking screening

The 2019 novel coronavirus (2019-nCoV) causes novel coronavirus pneumonia (NCP). Given that approved drug repurposing becomes a common strategy to quickly find antiviral treatments, a collection of FDA-approved drugs can be powerful resources for new anti-NCP indication discoveries. In addition to synthetic compounds, Chinese Patent Drugs (CPD), also play a key role in the treatment of virus related infections diseases in China. Here we compiled major components from 38 CPDs that are commonly used in the respiratory diseases and docked them against two drug targets, ACE2 receptor and viral main protease. According to our docking screening, 10 antiviral components, including hesperidin, saikosaponin A, rutin, corosolic acid, verbascoside, baicalin, glycyrrhizin, mulberroside A, cynaroside, and bilirubin, can directly bind to both host cell target ACE2 receptor and viral target main protease. In combination of the docking results, the natural abundance of the substances, and botanical knowledge, we proposed that artemisinin, rutin, glycyrrhizin, cholic acid, hyodeoxycholic acid, puerarin, oleanic acid, andrographolide, matrine, codeine, morphine, chlorogenic acid, and baicalin (or Yinhuang Injection containing chlorogenic acid and baicalin) might be of value for clinical trials during a 2019-nCov outbreak.

Antiviral potential of phytoligands against chymotrypsin-like protease of COVID‐19 virus using molecular docking studies: An optimistic approach

A recent outbreak of the novel coronavirus, COVID‐19, in the city of Wuhan, Hubei province, China and its ensuing worldwide spread have resulted in lakhs of infections and thousands of deaths. As of now, there are no registered therapies for treating the contagious COVID‐19 infections, henceforth drug repositioning may provide a fast way out. In the present study, a total of thirty-five compounds including commonly used anti-viral drugs were screened against chymotrypsin-like protease (3CLpro) using SwissDock. Interaction between amino acid of targeted protein and ligands was visualized by UCSF Chimera. Docking studies revealed that the phytochemicals such as cordifolin, anisofolin A, apigenin 7-glucoside, luteolin, laballenic acid, quercetin, luteolin-4-glucoside exhibited significant binding energy with the enzyme viz. – 8.77, -8.72, -8.36, -8.35, -8.13, -8.04 and -7.87 Kcal/Mol respectively. Therefore, new lead compounds can be used for drug development against SARS‐CoV‐2 infections.

Identification of potent COVID-19 main protease (Mpro) inhibitors from natural polyphenols: An in silico strategy unveils a hope against CORONA

COVID-19, a rapidly spreading new strain of coronavirus, has affected more than 150 countries and received worldwide attention. The lack of efficacious drugs or vaccines against SARS-CoV-2 has further worsened the situation. Thus, there is an urgent need to boost up research for the development of effective therapeutics and affordable diagnostic against COVID-19. The crystallized form of SARS-CoV-2 main protease (Mpro) was demonstrated by a Chinese researcher Liu et al. (2020) which is a novel therapeutic drug target. This study was conducted to evaluate the efficacy of medicinal plant-based bioactive compounds against COVID-19 Mpro by molecular docking study. Molecular docking investigations were performed by using Molegro Virtual Docker 7 to analyze the inhibition probability of these compounds against COVID-19. COVID-19 Mpro was docked with 80 flavonoid compounds and the binding energies were obtained from the docking of (PDB ID: 6LU7: Resolution 2.16 Å) with the native ligand. According to obtained results, hesperidin, rutin, diosmin, apiin, diacetylcurcumin, (E)-1-(2-Hydroxy-4-methoxyphenyl)-3-[3-[(E)-3-(2-hydroxy-4- methoxyphenyl)-3-oxoprop-1-enyl]phenyl]prop-2-en-1-one, and beta,beta’-(4-Methoxy-1,3- phenylene)bis(2′-hydroxy-4′,6′-dimethoxyacrylophenone have been found as more effective on COVID-19 than nelfinavir. So, this study will pave a way for doing advanced experimental research to evaluate the real medicinal potential of these compounds to cure COVID-19.

Potential of Flavonoid-Inspired Phytomedicines against COVID-19

Flavonoids are widely used as phytomedicines. Here, we report on flavonoid phytomedicines with potential for development into prophylactics or therapeutics against coronavirus disease 2019 (COVID-19). These flavonoid-based phytomedicines include: caflanone, Equivir, hesperetin, myricetin, and Linebacker. Our in silico studies show that these flavonoid-based molecules can bind with high affinity to the spike protein, helicase, and protease sites on the ACE2 receptor used by the severe acute respiratory syndrome coronavirus 2 to infect cells and cause COVID-19. Meanwhile, in vitro studies show potential of caflanone to inhibit virus entry factors including, ABL-2, cathepsin L, cytokines (IL-1β, IL-6, IL-8, Mip-1α, TNF-α), and PI4Kiiiβ as well as AXL-2, which facilitates mother-to-fetus transmission of coronavirus.

Since most of the drug candidates presently available for COVID-19 substantially act on viral main protease, by using molecular docking analysis, we have predicted the protease inhibitor activity of several natural products that can emerge as potential drug candidates inhibiting viral protease. A promising binding of natural products with the COVID-19 main protease was revealed by docking analysis. Among the several natural products screened by docking analysis, glycyrrhizin, tryptanthrine, rhein, and berberine were found to exhibit a higher degree of interaction with the viral protease accompanied by lowest binding energy with favorable drug-like properties. Thus these natural products may emerge as potential COVID-19 main protease inhibitor. However, additional exploration is inevitable for the investigation of the inherent use of the herbs containing these natural products and their in-vivo activity.

Targeting SARS-CoV-2 Spike Protein of COVID-19 with Naturally Occurring Phytochemicals

Spike glycoprotein found on the surface of SARS-CoV-2 (SARS-CoV-2S) is a class I fusion protein which helps the virus in its initial attachment with human Angiotensin converting enzyme 2 (ACE2) receptor and its consecutive fusion with the host cells. The attachment is mediated by the S1 subunit of the protein via its receptor binding domain. Upon binding with the receptor the protein changes its conformation from a pre-fusion to a post-fusion form. The membrane fusion and internalization of the virus is brought about by the S2 domain of the spike protein. From ancient times people have relied on naturally occurring substances like phytochemicals to fight against diseases and infection. Among these phytochemicals, flavonoids and non-flavonoids have been found to be the active source of different anti-microbial agents. Recently, studies have shown that these phytochemicals have essential anti-viral activities. We performed a molecular docking study using 10 potential naturally occurring flavonoids/non-flavonoids against the SARS-CoV-2 spike protein and compared their affinity with the FDA approved drug hydroxychloroquine (HCQ). Interestingly, the docking analysis suggested that C-terminal of S1 domain and S2 domain of the spike protein are important for binding with these compounds. Kamferol, curcumin, pterostilbene, and HCQ interact with the C-terminal of S1 domain with binding energies of -7.4, -7.1, -6.7 and -5.6 Kcal/mol, respectively. Fisetin, quercetin, isorhamnetin, genistein, luteolin, resveratrol and apigenin on the other hand, interact with the S2 domain of spike protein with the binding energies of -8.5, -8.5, -8.3, -8.2, -8.2, -7.9, -7.7 Kcal/mol, respectively. Our study suggested that, these flavonoid and non-flavonoid moieties have significantly high binding affinity for the two main important domains of the spike protein which is responsible for the attachment and internalization of the virus in the host cell and their binding affinities are much higher compared to that of HCQ. In addition, ADME (absorption, distribution, metabolism and excretion) analysis also suggested that these compounds consist of drug likeness property which may help for further explore as anti-SARS-CoV-2 agents. Further, in vitro and in vivo study of these compounds will provide a clear path for the development of novel compounds that would most likely prevent the receptor binding or internalization of the SARS-CoV-2 spike protein and therefore could be used as drugs for COVID-19 therapy.

Roles of flavonoids against coronavirus infection

In terms of public health, the 21st century has been characterized by coronavirus pandemics: in 2002-03 the virus SARS-CoV caused SARS; in 2012 MERS-CoV emerged and in 2019 a new human betacoronavirus strain, called SARS-CoV-2, caused the unprecedented COVID-19 outbreak. During the course of the current epidemic, medical challenges to save lives and scientific research aimed to reveal the genetic evolution and the biochemistry of the vital cycle of the new pathogen could lead to new preventive and therapeutic strategies against SARS-CoV-2. Up to now, there is no cure for COVID-19 and waiting for an efficacious vaccine, the development of “savage” protocols, based on “old” anti-inflammatory and anti-viral drugs represents a valid and alternative therapeutic approach. As an alternative or additional therapeutic/preventive option, different in silico and in vitro studies demonstrated that small natural molecules, belonging to polyphenols family, can interfere with various stages of coronavirus entry and replication cycle. Here, we reviewed the capacity of well-known (e.g. quercetin, baicalin, luteolin, hesperetin, gallocatechin gallate, epigallocatechin gallate) and uncommon (e.g. scutellarein, amentoflavone, papyriflavonol A) flavonoids, secondary metabolites widely present in plant tissues with antioxidant and anti-microbial functions, to inhibit key proteins involved in coronavirus infective cycle, such as PLpro, 3CLpro, NTPase/helicase. Due to their pleiotropic activities and lack of systemic toxicity, flavonoids and their derivative may represent target compounds to be tested in future clinical trials to enrich the drug arsenal against coronavirus infections.

In conclusion, the interest of scientists for the antiviral capacity of flavonoids against human coronavirus infections can benefit of the enormous amount of resources that governments, health agencies, and private companies are pouring in the field, searching for a cure against SARS-CoV-2. This situation barely resembles what happened in the eighties-nineties following the AIDS pandemic, when the basic knowledge in the immunological mechanisms controlling the response to HIV infection underwent amazing and unpredictable progresses. Waiting for a valuable vaccine against COVID-19, the pharmacological approach remains a priority and flavonoids may contribute to it. In this scenario, the “pleiotropic” properties of flavonoids that we mentioned at the beginning of this review, risks to become the passepartout to counteract coronaviruses since they can be effective on both sides, viral and host cells, to inhibit infection. In fact, recent works hypothesized that flavonoids can inhibit both TMPRSS2 and Furin, which cleave the SARS-CoV-2 Spike protein facilitating SARS-CoV-2 infectivity. Molecular docking-based screening and in vitro assays using recombinant proteins indicated that (−)-epicatechin 3-O-(3′-O-methyl) gallate for TMPRSS2 [] and baicalein and oroxylin A glycoside for Furin [] can bind and inhibit their respective proteases blocking virus propagation.

INGREDIENTS:

3,2᾿dihydroxyflavone
(3,2᾿DHF) & 3,4᾿dihydroxyflavone (3,4᾿DHF)

(Trifolium repens L.)

Influenza virus infection causes thousands of deaths and millions of hospitalizations worldwide every year and the emergence of resistance to anti-influenza drugs has prompted scientists to seek new natural antiviral materials. In this study, we screened 13 different flavonoids from various flavonoid groups to identify the most potent antiviral flavonoid against human influenza A/PR/8/34 (H1N1). The 3-hydroxyl group flavonoids, including 3,2᾿dihydroxyflavone (3,2᾿DHF) and 3,4᾿dihydroxyflavone (3,4᾿DHF), showed potent anti-influenza activity. They inhibited viral neuraminidase activity and viral adsorption onto cells. To confirm the anti-influenza activity of these flavonoids, we used an in vivo mouse model. In mice infected with human influenza, oral administration of 3,4᾿DHF significantly decreased virus titers and pathological changes in the lung and reduced body weight loss and death. Our data suggest that 3-hydroxyl group flavonoids, particularly 3,4᾿DHF, have potent antiviral activity against human influenza A/PR/8/34 (H1N1) in vitro and in vivo. Further clinical studies are needed to investigate the therapeutic and prophylactic potential of the 3-hydroxyl group flavonoids in treating influenza pandemics.

  1. Antiviral Activity Of 3, 4′-Dihydroxyflavone On Influenza A virus

  2. Plant–microbe interactions and secondary metabolites with antibacterial, antifungal and antiviral properties

  3. Antiviral effect of methylated flavonol isorhamnetin against influenza

6-gingerol
(ginger extract)

    1. A Brief Study On Zingiber Officinale-A Review
    2. A Mini Review On The Phytochemistry, Toxicology And Antiviral Activity Of Some Medically Interesting Zingiberaceae Species
    3. A Review On Medicinal Uses Of Zingiber Officinale (Ginger)
    4. Adsorption Of Polyphenols From Ginger Rhizomes On An Anion Exchange Resin Amberlite Ir-400–Study On Effect Of Ph And Temperature
    5. An Overview: Ginger, A Tremendous Herb
    6. Anticancer Effect Of Gingerol And Crude Ginger Extract On Ethylene Thiourea Induced Thyroid & Liver Cancer In Albino …
    7. Antimicrobial Activity Of Ginger (Zingiber Officinale) And Its Application In Food Products
    8. Antimicrobial Effect And Enzymatic Activity Of Extract Of Zingiber Officinale Roscoe And Stability In Topical Preparations
    9. Assessment Of Antimicrobial Potential Of 10% Ginger Extract Against Streptococcus Mutans, Candida Albicans, And Enterococcus Faecalis: An In Vitro Study
    10. Beneficial Therapeutic Effects Of Nigella Sativa And/Or Zingiber Officinale In Hcv Patients In Egypt
    11. Bioactive Compounds And Bioactivities Of Ginger (Zingiber Officinale Roscoe)
    12. Bioactive Principles And Nutraceuticals In Zingiberaceous Spices
    13. Biological Basis For The Use Of Botanicals In Osteoarthritis And Rheumatoid Arthritis: A Review
    14. Characterisation Of Ginger Extracts Obtained By Subcritical Water
    15. Chromatographic Analysis, Antioxidant, Anti-Inflammatory, And Xanthine Oxidase Inhibitory Activities Of Ginger Extracts And Its Reference Compounds
    16. Cyto-Biochemical And Antimicrobial Investigations On Essential Oil Of Zingiber Officinale Roscoe
    17. Effect Of 6‐Gingerol On Physicochemical Properties Of Grass Carp (Ctenopharyngodon Idellus) Surimi Fortified With Perilla Oil During Refrigerated Storage
    18. Effects Of Ginger Or Ginger And Thyme Extract In Laying Hens Feeding On Productive Results And Eggs Quality
    19. Ethanolic Extract Of Ginger On The Histology Of The Pancrease In Adult Wistar Rats
    20. Experimental Advances In Pharmacology Of Gingerol And Analogues
    21. Extract From Zingiber Officinale Rosc. In Oral Solid From Of A Drug
    22. Functional Coffee Substitute Prepared From Ginger By Subcritical Water
    23. Ginger And Its Bioactive Component Inhibit Enterotoxigenic Escherichia Coli Heat-Labile Enterotoxin-Induced Diarrhea In Mice
    24. Ginger And Its Constituents: Role In Prevention And Treatment Of Gastrointestinal Cancer
    25. Ginger As An Alternative Medicine To Urban Population–A Review
    26. Ginger Extract Inhibits The Replication Of T2 Bacteriophage By Inhibiting The Synthesis Of Nucleosides
    27. Ginger In Oral Care
    28. Ginger Rhizomes (Zingiber Officinale): A Spice With Multiple Health Beneficial Potentials
    29. Ginger: A Functional Herb
    30. Ginger: Panacea Or Consumer’S Hype?
    31. Harnessing The Therapeutic Properties Of Ginger (Zingiber Officinale Roscoe) For The Management Of Plant Diseases
    32. Herbal Antioxidant Agents And Its Pharmacological And Medicinal Properties
    33. Herbal Extracts As Antiviral Agents
    34. Inhibition Of Pro-Inflammatory Molecules By Ginger (Zingiber Officinale Roscoe) And Its Anti-Inflammatory Effects On Arthritis Patients
    35. Nutrient Profiling And Antioxidant Potential Of Three Different Varieties Of Zingiber Officinale.
    36. Pharmacological Activities Of Ginger (Zingiber Officinale): A Reviw
    37. Pharmacological Activity Of Zingiber Officinale
    38. Phytochemistry And Pharmacological Properties Of Ginger (Zingiber Officinale)
    39. Potential Health Benefits And Scientific Review Of Ginger
    40. Potential Pharmacological Benefits Of Ginger (Zingiber Officinale)–A
    41. Preparative Separation Of Gingerols From Zingiber Officinale By High-Speed Counter-Current Chromatography Using Stepwise Elution
    42. Protective And Therapeutic Potential Of Ginger (Zingiber Officinale) Extract And [6]‐Gingerol In Cancer: A Comprehensive Review
    43. Proven Health Benefits Of Ginger
    44. Review On Pharmacological Activities Of Mangifera Indica And Zingiber Officinale
    45. Some Medicinal Plant Extracts Exhibit Potency Against viral Hepatitis C
    46. Study On Microwave-Assisted Extraction Of Gingerol In Ginger
    47. Therapeutic Properties Of Zingiber Officinale Roscoe: A Review
    48. Toxic, Cytogenetic And Antitumor Evaluations Of [6]-Gingerol In Non-Clinical In Vitro Studies
    49. Traditional Health Boosters: Onion, Ginger And Garlic
    50. Zingiber Officinale (Ginger): A Future Outlook On Its Potential In Prevention And Treatment Of Diabetes And Prediabetic States
    51. Zingiber Officinale Roscoe Aqueous Extract Modulates Matrixmetalloproteinases And Tissue Inhibitors Of Metalloproteinases Expressions In Dengue virus -Infected Cells …
    52. Zingiberis Rhizoma: A Comprehensive Review On The Ginger Effect And Efficacy Profiles
    53. [6]-Gingerol Exhibits Potent Anti-Mycobacterial And Immunomodulatory Activity Against Tuberculosis
    54. 6-Gingerol Exerts Anti-Inflammatory Effects And Protective Properties On Lta-Induced Mastitis
    55. 6‐Gingerol Mediates Its Anti Tumor Activities In Human Oral And Cervical Cancer Cell Lines Through Apoptosis And Cell Cycle Arrest
    56. 6-Gingerol: A Therapeutically Potent Lead Candidate In Anti-Inflammatory Drug Discovery
    57. A Comparative Study Of The Anti-Breast Cancer And Immunomodulatory Effects Of [6]-,[8]-, And [10]-Gingerol
    58. A Ginger Component, 6-Gingerol Helps Prevention Of Sepsis By Inducing Anti-Bacterial Immune Responses
    59. A Phase Ii Randomized Double-Blind Placebo-Controlled Study Of 6-Gingerol As An Anti-Emetic In Solid Tumor Patients Receiving Moderately To Highly Emetogenic …
    60. Analgesic And Anti-Inflammatory Activities Of [6]-Gingerol
    61. Anti-Helicobacter Pylori Effect Of 6-Gingerol In Vitro
    62. Anti-Hyperglycaemic, Lipid Lowering And Anti-Oxidant Properties Of [6]-Gingerol In Db/Db Mice
    63. Anti‐Invasion Effects Of 6‐Shogaol And 6‐Gingerol, Two Active Components In Ginger, On Human Hepatocarcinoma Cells
    64. Anti-Oxidant Activity Of 6-Gingerol As A Hydroxyl Radical Scavenger By Hydrogen Atom Transfer, Radical Addition And Electron Transfer Mechanisms
    65. Assessment Of Anti-Cancerous Potential Of 6-Gingerol (Tongling White Ginger) And Its Synergy With Drugs On Human Cervical Adenocarcinoma Cells
    66. Bioinformatics And Experimental Studies Of Anti-Leukemic Activity From 6-Gingerol Demonstrate Its Role In P53 Mediated Apoptosis Pathway
    67. Comparative Antioxidant And Anti-Inflammatory Effects Of [6]-Gingerol,[8]-Gingerol,[10]-Gingerol And [6]-Shogaol
    68. Determination Of 6-Gingerol In Ginger Anti-Dandruff Shampoo By Hplc
    69. Determination Of 6-Gingerol In Taohua Anti-Diarrhea Granula By Hplc [J]
    70. Fabrication Of 6-Gingerol, Doxorubicin And Alginate Hydroxyapatite Into A Bio-Compatible Formulation: Enhanced Anti-Proliferative Effect On Breast And Liver …
    71. In Vitro Anti-Hydatic And Immunomodulatory Effects Of Ginger And [6] Gingerol
    72. In Vitro Anti-Hydatic And Immunomodulatory Effects Of Ginger And [6]-Gingerol
    73. Inhibition Of Adipogenesis In 3T3-L1 Cells By The Anti-Inflammatory Agents 6-Gingerol And Retinoic Acid
    74. Proteasome Inhibition Mediates P53 Reactivation And Anti-Cancer Activity Of 6-Gingerol In Cervical Cancer Cells
    75. Safety Evaluation Of Anti-Glioma Drug 6-Gingerol
    76. Structure–Activity Relationships Of 6-And 8-Gingerol Analogs As Anti-Biofilm Agents
    77. The Anti-Inflammatory Effect Of 6-Gingerol On Focal Ischemia-Reperfusion Injury In Rats

Acidicheteroglucan
(Tremella fuciformis extract)

Structure, bioactivities and applications of the polysaccharides from Tremella fuciformis mushroom: A review

Tremella fuciformis is an important edible mushroom that has been widely cultivated and used as food and medicinal ingredient in traditional Chinese medicine. In the past decades, many researchers have reported that T. fuciformis polysaccharides (TPS) possess various bioactivities, including anti-tumor, immunomodulatory, anti-oxidation, anti-aging, repairing brain memory impairment, anti-inflammatory, hypoglycemic and hypocholesterolemic. The structural characteristic of TPS has also been extensively investigated using advanced modern analytical technologies such as NMR, GC–MS, LC-MS and FT-IR to dissect the structure-activity relationship (SAR) of the TPS biomacromolecule. This article reviews the recent progress in the extraction, purification, structural characterization and applications of TPS.
In recent years, studies on the mechanism of polysaccharides have shown that polysaccharides have an immunosuppressive activity protecting against tumor growth. TPS exerts anti-tumor activity by promoting the host’s natural immune defenses. These polysaccharides can modulate the body’s immune functions by regulating immune organs, immune cells and immune molecules, and their immune activity without significant side effects [34]. TPS also has the effect of regulating body immunity and inhibiting tumor growth. Its inhibitory effect on tumors is achieved through the intermediate host effect, that is, by enhancing the body’s immune function to a tumor. TPS can inhibit the growth of Hep G22 cells and at concentrations of 50 mg/ml, the antitumor activity can reach 92% [12]. TPS can reduce side effects during treatment of tumors and can enable patients to rebuild their own immune system improving their cancer resistance [35]. Polysaccharides mainly play an immune function through macrophages, and macrophages can respond to infections, tumors and inflammation. Macrophages directly kill pathogens through phagocytosis and present antigens to elicit an immune response [36]. Macrophages produce a large number of biologically active molecules, including nitric oxide (NO), reactive oxygen species (ROS), and cytokines including tumor necrosis factor TNF-α, interleukin (IL)-1α, IL-1β, for defense of IL-6, IL-10 [37]. TPS can reverse the effect of proliferation and polarization of CD4+ T cells in Pseudomonas aeruginosa infected scald mice, resulting in a decline in the level of IL-10 [38]. TPS can inhibit modulate cyclophosphamide-induced mouse leukopenia. Leukocytes increase in a dose-dependent fashion [39]. Cyclophosphamide significantly reduces the mRNA expression of IL-1β, IL-4 and IL-12 in liver and spleen, and significantly increases the expression of TGF-β in liver and spleen. CY significantly reduces serum immune organ index and serum cytokine levels (IL-2, IL-12, INF-γ, and Ig G) and increases serum TGF-β levels. These results suggest that low-dose TPS has no obvious effect,
  1. Coccidiosis Immunization: Effects Of Mushroom And Herb Polysaccharides On Immune Responses Of Chickens Infected With Eimeria Tenella
  2. Effects Of Mushroom And Herb Polysaccharides On Cellular And Humoral Immune Responses Of Eimeria Tenella-Infected Chickens
  3. Effects Of Mushroom And Herb Polysaccharides, As Alternatives For An Antibiotic, On The Cecal Microbial Ecosystem In Broiler Chickens
  4. In Vitro Fermentation Characteristics Of Two Mushroom Species, An Herb, And Their Polysaccharide Fractions, Using Chicken Cecal Contents As Inoculum
  5. Interference Of Cranberry Constituents In Cell–Cell Signaling System Of Vibrio Harveyi
  6. Ringless Honey Mushroom (Armillaria Tabescens): Identification And Info
  7. Like the maitake and shiitake mushrooms, Tremella can enhance the immune system. The mushroom has acidic polysaccharides that boost the strength of white blood cells that protect the body from bacteria, virus es, and the like. In two separate studies, Tremella ranked alongside the maitake mushroom in terms of effectiveness in immune system enhancement.

Aconitum carmichaelii Debx extract
(Aconitum carmichaelii Debx)

Four diterpenoid alkaloids, namely, (a) hypaconitine, (b) songorine, (c) mesaconitine and (d) aconitine, were isolated from the ethanol root extract of Aconitum carmichaelii Debx. The antiviral activities of these alkaloids against tobacco mosaic virus (TMV) and cucumber mosaic virus (CMV) were evaluated. Antiviral activity test in vivo showed that compounds a and c, which were C19-diterpenoid alkaloids, showed inactivation efficacy values of 82.4 and 85.6% against TMV at 500 μg/mL, respectively. By contrast, compound c presented inactivation activity of 52.1% against CMV at 500 μg/mL, which was almost equal to that of the commercial Ningnanmycin (87.1% inactivation activity against TMV and 53.8% inactivation activity against CMV). C19-Diterpenoid alkaloids displayed moderate to high antiviral activity against TMV and CMV at 500 μg/mL, dosage plays an important role in antiviral activities. This paper is the first report on the evolution of aconite diterpenoid alkaloids for antiviral activity against CMV.

    1. Antiviral Activity Of Aconite Alkaloids From Aconitum Carmichaelii Debx
    2. Alkaloids isolated from the lateral root of Aconitum carmichaelii
    3. Application of metabolomics in toxicity evaluation of traditional Chinese medicines
    4. Effects of Magnolia officinalis compatibility with Polygala tenuifolia on mitochondrial metabolism in rats’ liver based on bio-thermodynamics
    5. Genus Tinospora: ethnopharmacology, phytochemistry, and pharmacology
    6. Herbs Used in Traditional Chinese Medicine in Treatment of Heart Diseases
    7. Indexed in Science Citation Index Expanded
    8. Market Survey On Traditionalmedicine Of The Third Month Fair In Dali Prefecture In Yunnan Province, Southwest China
    9. Preparative separation of C19-diterpenoid alkaloids from Aconitum carmichaelii Debx by pH‑zone-refining counter-current chromatography
    10. Protective effect of crude polysaccharide from Pao-Tian-Xiong derived from monkshood, against chronic renal failure in mice.
    11. Recent pharmaceutical evidence on the compatibility rationality of traditional Chinese medicine
    12. Safety Evaluation of Awei Capsule: Assessment of Acute and Subchronic Toxicity in rodent
    13. UPLC‐ESI/MS determination of 17 active constituents in two categorized formulas of traditional Chinese medicine, Sanhuang Xiexin Tang and Fuzi Xiexin Tang …

Ailanthus altissima stem bark extract
(Ailanthus altissima (Mill.) Swingle)

Virus-Cell Fusion Inhibitory Compounds from Ailanthus altissima Swingle

In order to search for the anti-HIV agents from natural products, eighty MeOH extracts of medicinal plants were applied to a syncytia formation inhibition assay which is based on the interaction between the HIV-1 envelope glycoprotein gp120/gp41 and the cellular membrane protein CD4 of T lymphocytes. Among them, Ailanthus altissima showed a potent virus-cell fusion inhibitory activity.

    1. Chemistry And Biological Activities Of Ailanthus Altissima Swingle: A Review
    2. Herbicidal Effect Of Ailanthus Altissima Leaves Water Extracts On Medicago Sativa Seeds Germination
    3. Pharmacological Evaluation Of Anti-Fertility Effect Of Stem Bark Of Ailanthus Altissima In Wistar Albino Rats
    4. Research On The In Vitro Bacteriostatic Effect Of Quassiawood Alkaloid On Escherichia Coli
    5. Screening Of Ailanthus Altissima Extract Paste Formula And Biological Determination
    6. Studies On The Control Efficiency Of Extracts From Leaves Of Ailanthus Altissima Swingle On Myzus Persicae Sulzer
    7. Verticillium Wilt Of Ailanthus Altissima
    8. Virus-cell fusion inhibitory compounds from Ailanthus altissima Swingle
    9. Antiviral effect of Ailanthus altissima and Brucea javanica on tobacco mosaic virus
    10. Anti-viral activity ofAilanthus altissima crude extract onRice stripe virus in rice suspension cells
    11. Quassinoids as inhibitors of Epstein-Barr virus early antigen activation
    12. Ailanthone induces G2/M cell cycle arrest and apoptosis of SGC‑7901 human gastric cancer cells
    13. Ailanthus altissima (the Tree of Heaven): In Vitro Culture and the Formation of Alkaloids and Quassinoids
    14. CAROTENOID PROFILE OF AILANTHUS ALTISSIMA STEM BARK, IN-VITRO ANTIOXIDANT AND ANTINEOPLASTIC ACTIVITIES
    15. Flavonoids from the leaves of Ailanthus altissima swingle and their antioxidant activity
    16. Medicinal plants: Prospective drug candidates against the dreaded Coronavirus
    17. Plants as sources of antimalarial and amoebicidal compounds
    18. Preclinical toxicology and toxicokinetic evaluation of ailanthone, a natural product against castration-resistant prostate cancer, in mice
    19. Protein patterns and chemical constituents of Ailanthus altissima (Miller) Swingle and Ailanthus excelsa Roxb.
    20. The Formation and Regulation of 1-Methoxycanthin-6-one Production in Ailanthus altissima Cell Suspension Cultures

    allantoin
    (Glyoxylic acid)

      1. A Review Of The Medicinal Properties And Applications Of Pycnanthus Angolensis (Welw) Warb
      2. Biguanide Related Compounds In Traditional Antidiabetic Functional Foods
      3. Biodiversity Conservation With Special Reference To Medicinal Climbers: Present Scenario, Challenges, Strategies, And Policies
      4. Estimation Influences Of Green Tea As Medical Herb For Treating Diabetes Mellitus
      5. Nitrogen Metabolism In Mosquitoes
      6. Synthesis And Reactivity Of 5-Methylenehydantoins
      7. The Utilization Of Urine Processing For The Advancement Of Life Support Technologies
      8. Compound for the control of herpes simplex virus using glycyrrhizic acid, lipoic acid, allantoin, and slippery elm
      9. Effect of Wen-Pi-Tang extract on lung damage by influenza virus infection
      10. The Two of Uninary Allantoin and Urea-N and Induction of Primary Moloney Sarcoma Virus-induced Tumors in Micice
      11. A quest of Anti-acne Potential of Herbal Medicines for extermination of MDR Staphylococcus aureus
      12. Acridine—a neglected antibacterial chromophore
      13. Alternative sources of fibrinolytic, anticoagulative, antimicrobial and anticancer molecules
      14. An in vitro antimicrobial comparison of miswak extract with commercially available non‐alcohol mouthrinses
      15. An investigation into multifaceted mechanisms of action of allantoin in wound healing
      16. An overview of antimicrobial properties of different classes of phytochemicals
      17. antibacterial Activity of Aristolochia bracteata Root Extracts
      18. antibacterial ACTIVITY OF SOME TERRESTRIAL GASTROPODS FROM EGYPT AGAINST STAPHYLOCOCCUS AUREUS AND ESCHERICHIA COLI
      19. antibacterial and antifungal activities of proteins extracted from seven different snails
      20. antibacterial and Antioxidant Activities of the Essential Oil from the Roots of Angelica tennuifolia
      21. antibacterial potential of secondary metabolites produced by Aspergillus sp., an endophyte of Mitrephora wangii
      22. antibacterial PROPERTIES OF CRUDE AQUEOUS Hylocereus polyrhizus PEEL EXTRACTS IN LIPSTICK FORMULATION AGAINST GRAM-POSITIVE …
      23. antibacterial properties of human amniotic membranes
      24. Anti-Inflammatory and antibacterial Activity of the Chitosan/Chlorhexidine Gel Commercial Preparation for Postexodontia Treatment: An In Vitro Study
      25. antimicrobial activities of extracts and flavonoid glycosides of corn silk (Zea mays L)
      26. antimicrobial activities ofStreptomyces pulcher, S. canescens andS. citreofluorescens against fungal and bacterial pathogens of tomatoin vitro
      27. antimicrobial activity and phytochemical properties of corn (Zea mays L.) silk
      28. antimicrobial activity of copaiba oil: A review and a call for further research
      29. antimicrobial activity of enterocins from Enterococcus faecalis SL-5 against Propionibacterium acnes, the causative agent in acne vulgaris, and its therapeutic effect
      30. antimicrobial activity of various parts of Polyalthia longifolia var. pendula: isolation of active principles from the leaves and the berries
      31. antimicrobial compounds from the excretions of surgical maggots, Lucilia sericata (Meigen) (Diptera, Calliphoridae)
      32. antimicrobial Effect of Cow Urine and Goat Urine against common Dental Caries Pathogens: An in vitro Comparative Study
      33. antimicrobial materials derived from the endophytic fungus Fusarium sp. of Eucommia ulmoides
      34. antimicrobial meroterpenoids from the endophytic fungus Penicillium sp. T2-8 associated with Gastrodia elata
      35. antimicrobial Metabolites from the Endophytic Fungus Aspergillus sp. of Eucommia ulmoides
      36. antimicrobial N-brominated hydantoin and uracil grafted polystyrene beads
      37. antimicrobial treatments of hemp fibers grafted with β-cyclodextrin derivatives
      38. Antimicrobial, antioxidant and cytotoxic activity of silver nanoparticles synthesized by leaf extract of Erythrina suberosa (Roxb.)
      39. Antimycobacterial, antimicrobial, antioxidant activities and in silico PASS investigations of root fractions and extract of Cordia dichotoma Forst
      40. Antioxidant and antibacterial Effects of Some Medicinal Plants of Iran
      41. Antioxidant and antimicrobial activities of Salvia multicaulis
      42. Antioxidant and antimicrobial activity of a new generation phyto-gel
      43. Antioxidative, antimicrobial and anticytotoxic activities of seungmagalgeuntang and fermented seungmagalgeuntang
      44. Biosynthesis and antibacterial activity of silver and gold nanoparticles from the leaf and callus extracts of Amaranthus dubius, Gunnera perpensa, Ceratotheca …
      45. Biosynthesis of mixed nanocrystalline Zn–Mg–Cu oxide nanocomposites and their antimicrobial behavior
      46. Calendula (Calendula officinalis)
      47. Camphor oil extraction from Cinnamomum camphora and its antibacterial activity [J]
      48. Catalyst-Free Three-Component Synthesis, Antibacterial, Antifungal, and Docking Studies of Spiroindoline Derivatives
      49. Characterization, antimicrobial, antioxidant, and anticoagulant activities of silver nanoparticles synthesized from Petiveria alliacea L. leaf extract
      50. Chemical Composition and antibacterial Effect of Plantago Major Extract on Periodontal Pathogens
      51. Chemical Constituents and antimicrobial Activity of Branches and Leaves of Cordia insignis (Boraginaceae)
      52. Comparison of some secondary metabolite content in the seventeen species of the Boraginaceae family
      53. Copper-releasing, borate-based glasses with antibacterial properties: synthesis and in vitro characterization
      54. Cytotoxicity, antiviral and antimicrobial activities of alkaloids, flavonoids, and phenolic acids
      55. Development and evaluation of antimicrobial herbal cosmetic preparation
      56. Dopa-based facile procedure to synthesize AgNP/cellulose nanofiber composite for antibacterial applications
      57. Ecofriendly Biosynthesis of Zinc Oxide and Magnesium Oxide Particles from Medicinal Plant Pisonia grandis R.Br. Leaf Extract and Their antimicrobial Activity
      58. Empirical formula: C4 H9 O7 Al2 Cl N4
      59. Evaluation for the Antimicrobial, Antioxidant and Antithrombosis Activity of Natural Spices for Fresh-cut yam.
      60. Evaluation of antibacterial Activity and Phenolic Contents of Four Nigerian Medicinal Plants
      61. Evaluation of antibacterial and antitumor activities of some Turkish endemic plants
      62. Evaluation of antimicrobial, antithrombin, and antioxidant activity of Aerial Bulbils of Dioscorea batatas Decne
      63. Evaluation of antimicrobial, antithrombin, and antioxidant activity of Dioscorea batatas Decne
      64. Evidence on antimicrobial Efficacy of Commercial Toothpaste
      65. Experiment-based quantitative modeling for the antibacterial activity of silver nanoparticles
      66. extracts obtained from stigmata of Zea mays L. against uropathogenic E. coli and Benzethonium chloride as frequent contaminant faking potential antibacterial …
      67. Fabrication of bioinspired chitosan/gelatin/allantoin biocomposite film for wound dressing application
      68. Formulation and evaluation of antibacterial creams and gels containing metal ions for topical application
      69. Genomic analysis unveils important aspects of population structure, virulence, and antimicrobial resistance in Klebsiella aerogenes
      70. Globularia alypum methanolic extract improves burn wound healing process and inflammation in rats and possesses antibacterial and antioxidant activities
      71. In vitro antibacterial activity of selected medicinal plants traditionally used in Iran against plant and human pathogenic bacteria
      72. In vivo antioxidative property, antimicrobial and wound healing activity of flower extracts of Pyrostegia venusta (Ker Gawl) Miers
      73. Isolation and Structural Elucidation of Allantoin a Bioactive Compound from Cleome viscosa L.: A Combined Experimental and Computational Investigation
      74. Lucifensin, the long-sought antimicrobial factor of medicinal maggots of the blowfly Lucilia sericata
      75. New antimicrobial alkaloids from the roots of Polyalthia longifolia var. pendula
      76. Nigritanine as a New Potential antimicrobial Alkaloid for the Treatment of Staphylococcus aureus-Induced Infections
      77. Novel streptopyrroles from Streptomyces rimosus with bacterial protein histidine kinase inhibitory and antimicrobial activities
      78. Preclinical study of the efficacy and safety of wound healing gel containing chitosan, taurine and allantoin
      79. Preparation and characteristics of antibacterial chitosan films modified with N-halamine for biomedical application
      80. Qualitative Determination of the Secondary Metabolites and Evaluation of the antimicrobial Activity of Leaf Extracts from Different Plant Families (Boraginaceae …
      81. Screening the UV-blocking and antimicrobial properties of herbal nanoparticles prepared from Aloe vera leaves for textile applications
      82. Secondary metabolites from the Actinomycete Acrocarpospora punica
      83. Selective antimicrobial activity of maggots against pathogenic bacteria
      84. Solid lipid nanoparticles containing copaiba oil and allantoin: development and role of nanoencapsulation on the antifungal activity
      85. Stability, antibacterial ability, and inhibition of “zinc burning” of amitrole as thermal stabilizer for transparent poly (vinyl chloride)
      86. STUDY OF antimicrobial AND HAIR REGROWTH ACTIVITY OF TRIDAX PROCUMBENS FOR SCALP DISORDER
      87. Study on Synthesis of Diazolidinyl Urea as Preservative [J]
      88. Supramolecular Hydrogels Based on Cellulose for Sustained Release of Therapeutic Substances with antimicrobial and Wound Healing Properties
      89. Survey of the antimicrobial Activity of Commercially Available Australian Tea Tree (Melaleuca alternifolia) Essential Oil Products In Vitro
      90. The effects of a topical gel containing chitosan, 0, 2% chlorhexidine, allantoin and despanthenol on the wound healing process subsequent to impacted lower …
      91. The identification and quantification of bioactive compounds from the aqueous extract of comfrey root by UHPLC-DAD-HESI-MS method and its microbial activity
      92. The identification and quantification of bioactive compounds from the aqueous extract of comfrey root by…
      93. The pharmacology of Anchusa italica and Anchusa strigosa–A review
      94. The physical properties, antioxidant and antimicrobial activity of chitosan–gelatin edible films incorporated with the extract from hop plant
      95. Urate Oxidase produced by Lucilia sericata medical maggots is localized in Malpighian tubes and facilitates allantoin production

    Alphitonia philippinensis stems
    (Alphitonia philippinensis Braid)

    Flavonol glycosides derived from the stems of Alphitonia philippinensis have been reported to inhibit the replication of HSV-1.

    Three new flavonol glycosides, namely, isorhamnetin 3-O-(6″-O-(Z)-p-coumaroyl)-β-d-glucopyranoside, quercetin 3-O-α-l-rhamnopyranosyl(1-2)-α-l-arabinopyranosyl(1-2)-α-l-rhamnopyranoside, and quercetin 3-O-α-l-arabinopyranosyl(1-2)-α-l-rhamnopyranoside, were isolated from the stems of Alphitonia philippinensis collected from Hainan Island, China. Some of the isolated triterpenoids and flavonoid glycosides showed cytotoxicity against human PC-3 cells and hepatoma HA22T cells, and the inhibition of replication on HSV-1 (). Viral diseases, especially of skin, can be treated with a virucide encapsulated in multilamellar phospholipid liposomes. Rosmarinic acid (70), incorporated in phospholipid mixture demonstrated effectiveness in humans afflicted with HSV (). Flavonol glycosides (from quercetin and isorhamnetin) derived from the stems of Alphitonia philippinensis have been reported to inhibit the replication of HSV-1.

      1. Evaluation Of Antioxidant Activity And Phytochemical Screening Of Leaves, Barks, Stems And Fruits Of Alphitonia Philippinensis (Rhamnaceae) From Brunei …
      2. Triterpenoids With A Five-Membered A-Ring: Distribution In Nature, Transformations, Synthesis, And Biological Activity
      3. Antiviral activity of phytochemicals: a current perspective
      4. Gastroprotective activity of the hydroethanolic extract and ethyl acetate fraction from Kalanchoe pinnata (Lam.) Pers.
      5. Medicinal uses of selected fruit trees and woody perennials

    Amygdalin
    (Semen Armeniacae Amarum Extract)

    Contribution of traditional Chinese medicine to the treatment of COVID-19

    Amygdalin could Inhibit IFN-γ, NF-κB and NLRP3 signaling pathways so as to reduce the inflammatory response (Paoletti et al., 2013; Zhang et al., 2017). These reports provided the scientific ground of integrating TCM therapy from the aspects of their compositions’ potential targeting proteins and signaling pathways in the treatment of COVID-19.

    1. A Network Analysis Of The Chinese Medicine Lianhua-Qingwen Formula To Identify Its Main Effective Components
    2. Antitussive, Anti-Pyretic And Toxicological Evaluation Of Ma-Xing-Gan-Shi-Tang In Rodents
    3. Anti-virus Effect Of Traditional Chinese Medicine Yi-Fu-Qing Granule On Acute Respiratory Tract Infections.
    4. Chinese Herbal Medicine For Coronavirus Disease 2019: A Systematic Review And Meta-Analysis
    5. Determination Of Amygdalin In Maxing Shigan Decoction By Hpce
    6. Determination The Active Compounds Of Herbal Preparation By Uhplc–Ms/Ms And Its Application On The Preclinical Pharmacokinetics Of Pure Ephedrine, Single Herbal …
    7. Effect Of Compatibility On Content Of Amygdalin In Sanao Decoction
    8. Effects Of Different Principles Of Traditional Chinese Medicine Treatment On Tlr7/Nf-Κb Signaling Pathway In Influenza virus Infected Mice
    9. Ma Xing Shi Gan Decoction Attenuates Pm2. 5 Induced Lung Injury Via Inhibiting Hmgb1/Tlr4/Nfκb Signal Pathway In Rat
    10. Yidu-Toxicity Blocking Lung Decoction Ameliorates Inflammation In Severe Pneumonia Of Sars-Cov-2 Patients With Yidu-Toxicity Blocking Lung Syndrome By …

    Anemarrhena asphodeloides extract
    (Anemarrhena asphodeloides Bunge)

    Anti-respiratory syncytial virus (RSV) activity of timosaponin A-III from the rhizomes of Anemarrhena asphodeloides

    Two known steroidal saponins, timosaponin A-III (1) and anemarsaponin B (2) were isolated from the BuOH fraction of the rhizomes of Anemarrhena asphodeloides Bunge (Liliaceae) together with the xanthone derivatives, mangiferin (3) and neomangiferin (4). Structures of the isolates were identified using 1D and 2D NMR techniques and by comparison with the published values. Timosaponin A-III (1) exhibited potent inhibitory effects on the respiratory syncytial virus (RSV), with an IC50 value of 1.00 µM.

    1. (-)-Nyasol (Cis-Hinokiresinol), A Norneolignan From The Rhizomes Of Anemarrhena Asphodeloides, Is A Broad Spectrum Inhibitor Of Eicosanoid And Nitric Oxide …
    2. A Fructan From Anemarrhena Asphodeloides Bunge Showing Neuroprotective And Immunoregulatory Effects
    3. A Metabolomic Approach To Determine The Geographical Origins Of Anemarrhena Asphodeloides By Using Uplc–Qtof Ms
    4. Anemarrhenae Asphodeloides Rhizoma Extract Enriched In Mangiferin Protects Pc12 Cells Against A Neurotoxic Agent-3-Nitropropionic Acid
    5. Anti-Inflammatory Effect Of Anemarsaponin B Isolated From The Rhizomes Of Anemarrhena Asphodeloides In Lps-Induced Raw 264.7 Macrophages Is Mediated By …
    6. Anti-Inflammatory Effect Of Win-34B, A New Herbal Formula For Osteoarthritis Composed Of Lonicera Japonica Thunb And Anemarrhena Asphodeloides Bunge In …
    7. Anti-Respiratory Syncytial virus (Rsv) Activity Of Timosaponin A-Iii From The Rhizomes Of Anemarrhena Asphodeloides
    8. Identification Of Nyasol And Structurally Related Compounds As The Active Principles From Anemarrhena Asphodeloides Against Respiratory Syncytial virus (Rsv)
    9. The Genus Anemarrhena Bunge: A Review On Ethnopharmacology, Phytochemistry And Pharmacology


    Angelica sinensis
    (Angelica sinensis (Oliv.) Diels)

    Increased oxidative stress and disturbed glutathione redox system play an important role in the pathogenesis of human immunodeficiency virus (HIV) infection. Depletion in intracellular levels of reduced glutathione (GSH) contributes to an increment in tumor necrosis factor α (TNF-α)-stimulated-HIV-1-transcription, activation of HIV-1-replication, sensitivity to TNF-α-induced cell death, and impairment of CD4+ cell function and survival. Therefore, several studies have investigated the effect of GSH-enhancer agents such as N-acetyl cystein in the treatment of patients with HIV infection. With regard to the beneficial effects of Angelica sinensis, a Chinese medicinal herb, on GSH redox system and the pathogenic role of GSH depletion in HIV infection and the immunomodulator effects of active ingredients of this herb, we postulated that Angelica sinensis may be of value in the treatment of HIV-infected patients.

    1. Angelica Sinensis Polysaccharide Attenuates Concanavalin A-Induced Liver Injury In Mice
    2. Antiviral Activity Of Guiqi Polysaccharides Against Enterovirus 71 In Vitro
    3. Biotransformation Of Neuro-Inflammation Inhibitor Kellerin Using Angelica Sinensis (Oliv.) Diels Callus
    4. Dong Quai (Angelica Sinensis [Oliv.] Diels), Chinese Angelica
    5. Lowering Sugar Effect And Mechanism Of Angelica Polysaccharide To Wister Diabetic Rats Induced By Stz [J]
    6. Macrophage Activation By An Acidic Polysaccharide Isolated From Angelica Sinensis (Oliv.) Diels
    7. Pharmacological Action And Toxicity Of Angelica Sinensis
    8. Radix Angelica Sinensis Soup Production By Decocting Process Using High Pressure
    9. Therapeutic Effect Of Qigui Tangtong Ning Granules On Diabetic Peripheral Neuropathy In Rats
    10. Use Of A Magnetic Ultrafiltration Membrane For The Separation Of Angelica Sinensis Root Polysaccharides [J]


    Apigenin
    (celery extract)

    Targeting SARS-CoV-2 Spike Protein of COVID-19 with Naturally Occurring Phytochemicals

    Apigenin has shown potent antiviral activity against hepatitis B virus, adenoviruses, african swine fever virus and some RNA viruses in vitro.

    1. Anti‐Obesity Effects Of Enzyme‐Treated Celery Extract In Mice Fed With High‐Fat Diet
    2. Apigenin Inhibits African Swine Fever virus Infection In Vitro
    3. Botanical Therapeutics: Phytochemical Screening And Biological Assessment Of Chamomile, Parsley And Celery Extracts Against A375 Human Melanoma …
    4. Inhibition Of Epstein-Barr virus Reactivation By The Flavonoid Apigenin
    5. Potency Of Herbal Plants Formulation As Anticholesterole Agent: In Vitro Studies
    6. Role Of Phenolic Compounds In Peptic Ulcer: An Overview
    7. The Expected Protective Role Of Celery Oil On Induced Toxic Effects Of Acrylamide On The Testis Of Adult Albino Rat: A Morphological, Morphometric And …
    8. The Flavonoid Apigenin Inhibits Hepatitis C virus Replication By Decreasing Mature Microrna122 Levels

    arctigeNin, arctin
    (Burdock extract (Arctium Lappa))

    Arctiin and its aglucone, arctigenin from the fruits of Arctium lappa L. showed potent in vitro antiviral activities against influenza A virus (A/NWS/33, H1N1) (IFV). Based on the data from time-of-addition experiments and on release tests of progeny viruses, arctigenin was assumed to interfere with early event(s) of viral replication after viral penetration into cells, and to suppress the release of progeny viruses from the host cells. Arctiin was orally effective against either IFV-inoculated normal or 5-fluorouracil (5-FU)-treated mice, being less effective as compared with oseltamivir. Noticeably, arctiin produced a larger amount of virus-specific antibody than those of control and oseltamivir in sera collected from 5-FU-treated mice. Furthermore, oral treatment of 5-FU-treated mice with arctiin did not induce any resistant viruses, although the same treatment with oseltamivir induced resistant viruses at a 50% frequency. When the combination of arctiin and oseltamivir was administered to normal mice infected with IFV, the virus yields in both bronchoalveolar lavage fluids and lungs were significantly reduced relative to those in the mice treated with arctiin or oseltamivir alone. Thus, monotherapy of arctiin or combined therapy of arctiin with oseltamivir would be another treatment option for influenza.

    1. Therapeutic effect of arctiin and arctigenin in immunocompetent and immunocompromised mice infected with influenza A virus
    2. Evaluation on the antiviral activity of arctigenin against spring viraemia of carp virus
    3. Synthesis and in vitro activities evaluation of arctigenin derivatives against spring viraemia of carp virus
    4. Arctigenin as a lead structure for inhibitors of human immunodeficiency virus type-1 integrase
    5. Synthesis and antiviral activity of a new arctigenin derivative against IHNV (infectious hematopoietic necrosis virus) in vitro and in vivo
    6. Antioxidants: potential antiviral agents for Japanese encephalitis virus infection
    7. Antiviral activity of Arctigenin against Newcastle Disease virus in vitro
    8. Evaluation on antiviral activity of a novel arctigenin derivative against multiple rhabdoviruses in aquaculture
    9. Plant-derived leading compounds for chemotherapy of human immunodeficiency virus (HIV) infection

    artemisinin
    (Artemisia annua extract)

    Discuss about the application of Artemisia annua prescriptions in the treatment of COVID-19

    The applications of traditional Chinese medicine (TCM) have been playing an important role in treating the epidemics of Coronavirus Disease 2019 (COVID-19), which is now prevalent all over the world. Exploring the mechanisms of TCM compound prescriptions might be difficult though, pharmacological studies on elucidating the effective components of TCM could serve as the experimental basis in the application of TCM compound prescription in treating COVID-19. As the critical active ingredients of Qinghao (Artemisia annua), artemisinin was initially used as antimalaria drug. Artemisia annua prescriptions take significant effect against pneumonia. Sharing similarities in pharmacology with artemisinin, chloroquine has been confirmed effective in inhibiting Severe Acute Respiratory Syndrome coronavirus 2 (SARS-Cov-2) both in vitro and practically. In this context, we discussed the application of Artemisia annua prescriptions against COVID-19 along with the antiviral effect of chloroquine.

    Conclusion

    With similar pharmacological effects between chloroquine and artemisinin in treating infectious diseases, this paper discusses the modern scientific basis for the application of Artemisia annua prescriptions in COVID-19. Except for antimalarial, most of the other pharmacological studies on artemisinin and its derivatives are still on the bench or at animal level, with only a few in clinical trials. Artemisinin treatment on COVID-19 has not been reported yet. As a treasure of TCM, compound prescription has played an important role in plagues in history. The main cause of COVID-19 in Wuhan is damp-heat according to TCM theory. The prescription for clearing heat and eliminating dampness based on Artemisia annua is widely used in this epidemic. Based on the antiviral and anti-inflammatory effects of artemisinin and its derivatives, Artemisia annua prescriptions have great value to dig into and are promising to be used in more infectious diseases. But more in vitro experiments need to be carried out to provide more evidence, such as the influence of Artemisia or Artemisia annua prescriptions on inflammatory factors express

    1. Access To New Highly Potent Antileukemia, Antiviral And Antimalarial Agents Via Hybridization Of Natural Products (Homo) Egonol, Thymoquinone And Artemisinin
    2. Antiviral Effect Of Artemisinin From Artemisia Annua Against A Model Member Of The Flaviviridae Family, The Bovine viral Diarrhoea virus (Bvdv)
    3. Artemisia Annua (Sweet Annie), Other Artemisia Species, Artemisinin, Artemisinin Derivatives, And Malaria
    4. Artemisia Annua: Trials Are Needed For Covid‐19
    5. Artemisinin Analogues As Potent Inhibitors Of In Vitro Hepatitis C virus Replication
    6. Crystallization Of Artemisinin From Chromatography Fractions Of Artemisia Annua Extract
    7. Delayed Clearance Of Plasmodium Falciparum In Patients With Human Immunodeficiency virus Co-Infection Treated With Artemisinin
    8. Effect Of Artemisinin/Artesunate As Inhibitors Of Hepatitis B virus Production In An “In Vitro” Replicative System
    9. Frontispiece: Synthesis Of Artemisinin‐Derived Dimers, Trimers And Dendrimers: Investigation Of Their Antimalarial And Antiviral Activities Including Putative …
    10. Hemin Potentiates The Anti-Hepatitis C virus Activity Of The Antimalarial Drug Artemisinin
    11. Highly Potent Artemisinin-Derived Dimers And Trimers: Synthesis And Evaluation Of Their Antimalarial, Antileukemia And Antiviral Activities
    12. Stability And Antiviral Activity Against Human Cytomegalovirus Of Artemisinin Derivatives
    13. Synthesis And In Vitro Anti-Human Immunodeficiency virus Activity Of Artemisinin (Qinghaosu)-Related Trioxanes
    14. Synthesis Of Artemisinin‐Derived Dimers, Trimers And Dendrimers: Investigation Of Their Antimalarial And Antiviral Activities Including Putative Mechanisms Of Action
    15. Synthesis Of Thymoquinone–Artemisinin Hybrids: New Potent Antileukemia, Antiviral, And Antimalarial Agents
    16. The Antiviral Activities Of Artemisinin And Artesunate

    aspalathin
    (ROOIBOS tea)

    Aspalathus Linearis (Burm.f.) R. Dahlrgen (Rooibos)

    Aspalathin and nothofagin extracted from Rooibos have been shown to effectively inhibit LPS-induced release of HMGB1, and suppressed HMGB1-mediated septic responses, such as hyperpermeability, adhesion and migration of leukocytes, and expression of cell adhesion molecules [124]. These molecules, as part of ethanol and alkaline extracts of the Rooibos plant, have also been shown to reduce Influenza A viral load at a late stage of the infection in vitro [125].
    1. A Kinetic And Equilibrium Study Of Rooibos Tea Infusions.
    2. A Review Of The Bioactivity Of South African Herbal Teas: Rooibos (Aspalathus Linearis) And Honeybush (Cyclopia Intermedia)
    3. Antioxidant Properties Of Rooibos (Aspalathus Linearis)–In Vitro And In Vivo Evidence
    4. Antioxidants Of Rooibos Tea-A Possible Explanation For Its Health Promoting Properties?
    5. Antiviral Activity Of Aspalathus Linearis Against Human Influenza virus
    6. Aspalathin A Unique Phytochemical From The South African Rooibos Plant (Aspalathus Linearis): A Mini Review
    7. Commercially Important Medicinal Plants Of South Africa: A Review
    8. Concise Total Syntheses Of Aspalathin And Nothofagin
    9. Development Of A Sensory Lexicon And Sensory Wheel For Rooibos (Aspalathus Linearis) And The Role Of Its Phenolic Composition On Taste And Mouthfeel.
    10. Effect Of Rooibos (Aspalathus Linearis) On Growth Control Of Clostridium Perfringens And Lipid Oxidation Of Ready‐To‐Eat Jokbal (Pig’S Trotters)
    11. Hepatotoxicity Due To Red Bush Tea Consumption: A Case Report
    12. Identification Of Phenolic Compounds In Aqueous And Ethanolic Rooibos Extracts (Aspalathus Linearis) By Hplc-Esi-Ms (Tof/It)
    13. Rooibos Tea As A Likely Health Food Supplement
    14. Rooibos Tea Extracts Inhibit Osteoclast Formation And Activity Through The Attenuation Of Nf-Κb Activity In Raw264. 7 Murine Macrophages
    15. Rooibos Tea: New Research Documents Antioxidant And Anticancer Properties
    16. Rooibos Tea: Research Into Antioxidant And Antimutagenic Properties
    17. Rooibos-The New” White Tea” For Hair And Skin Care
    18. Selective Bronchodilatory Effect Of Rooibos Tea (Aspalathus Linearis) And Its Flavonoid, Chrysoeriol
    19. Tea And Bone Health: Findings From Human Studies, Potential Mechanisms, And Identification Of Knowledge Gaps
    20. The Transport Of The Rooibos Tea Flavonoid Aspalathin Across The Skin And The Intestinal Epithelium
    21. Traditional Medicines In Africa: An Appraisal Of Ten Potent African Medicinal Plants

    atractylodin ,β-eudesmol,hinesol,hydroxy-atractylo
    (Rhizoma Areactylodis Lanceae extract)

    Antiviral activities of atractylon from Atractylodis Rhizoma

    Atractylodis Rhizoma is a traditional medicinal herb, which has antibacterial, antiviral, anti-inflammatory and anti-allergic, anticancer, gastroprotective and neuroprotective activities. It is widely used for treating fever, cold, phlegm, edema and arthralgia syndrome in South-East Asian nations. In this study, 6 chemical compositions of Atractylodis Rhizoma were characterized by spectral analysis and their antiviral activities were evaluated in vitro and in vivo. Among them, atractylon showed most significant antiviral activities. Atractylon treatment at doses of 10–40 mg/kg for 5 days attenuated influenza A virus (IAV)-induced pulmonary injury and decreased the serum levels of interleukin (IL)-6, tumor necrosis factor-α and IL-1β, but increased interferon-β (IFN-β) levels. Atractylon treatment upregulated the expression of Toll-like receptor 7 (TLR7), MyD88, tumor necrosis factor receptor-associated factor 6 and IFN-β mRNA but downregulated nuclear factor-κB p65 protein expression in the lung tissues of IAV-infected mice. These results demonstrated that atractylon significantly alleviated IAV-induced lung injury via regulating the TLR7 signaling pathway, and may warrant further evaluation as a possible agent for IAV treatment.
    1. Alisol a 24-acetate isolated from the Alismatis Rhizoma improves hepatic lipid deposition in hyperlipidemic mice by ABCA1/ABCG1 pathway
    2. Antiviral herbs-present and future
    3. Berberine and its derivatives: a patent review (2009–2012)
    4. Clinical studies of immunomodulatory activities of Yunzhi-Danshen in breast cancer and nasopharyngeal carcinoma patients, and Lingzhi-San Miao San in …
    5. Determination of Hinesol in Rhizoma Atraxtylodis from Different Areas [J]
    6. Erzhu Qinggan Jiedu Recipe improves the clinical outcome of hepatocellular Cancer after surgical resection: a case–control retrospective study
    7. Immunostimulants in traditional Chinese medicine
    8. Pharmacological effects of medicinal components of Atractylodes lancea (Thunb.) DC.
    9. Radix Bupleuri: a review of traditional uses, botany, phytochemistry, pharmacology, and toxicology
    10. Research Development on Prepared Method and Theoretical Research of Rhizome Atractylodis [J]
    11. The Transcript Profile of a Traditional Chinese Medicine, Atractylodes lancea, Revealing Its Sesquiterpenoid Biosynthesis of the Major Active Components


    Baicalein
    (Scutellaria baicalensis Georgi)

    1. Antigastritic And Anti Helicobacter Pylori Effects Of Baicalein From Scutellaria Baicalensis
    2. Antioxidative And Anti-Inflammatory Activities Of Polyhydroxyflavonoids Of Scutellaria Baicalensis Georgi
    3. Antiviral Activity Of Baicalein And Quercetin Against The Japanese Encephalitis virus
    4. Antiviral Activity Of Silymarin In Comparison With Baicalein Against Ev-A71
    5. Antiviral Effects Of Baicalein On Human Cytomegalovirus In Vitro
    6. Arsenic Accumulation In Scutellaria Baicalensis Georgi And Its Effects On Plant Growth And Pharmaceutical Components
    7. Baicalein Attenuates Inflammatory Responses By Suppressing Tlr4 Mediated Nf-Κb And Mapk Signaling Pathways In Lps-Induced Mastitis In Mice
    8. Baicalein Induces Apoptosis In Scc-4 Human Tongue Cancer Cells Via A Ca2+-Dependent Mitochondrial Pathway
    9. Baicalein Induces Apoptosis Through Ros-Mediated Mitochondrial Dysfunction Pathway In Hl-60 Cells.
    10. Baicalein Inhibits Il-1Β-And Tnf-Α-Induced Inflammatory Cytokine Production From Human Mast Cells Via Regulation Of The Nf-Κb Pathway
    11. Baicalein Protects Against Cardiac Hypertrophy Through Blocking Mek‐Erk1/2 Signaling
    12. Baicalein, An Active Component Of Scutellaria Baicalensis Georgi, Prevents Lysophosphatidylcholine-Induced Cardiac Injury By Reducing Reactive Oxygen …
    13. Baicalein, Ethyl Acetate, And Chloroform Extracts Of Scutellaria Baicalensis Inhibit The Neuraminidase Activity Of Pandemic 2009 H1N1 And Seasonal Influenza …
    14. Baicalin From Scutellaria Baicalensis Blocks Respiratory Syncytial virus (Rsv) Infection And Reduces Inflammatory Cell Infiltration And Lung Injury In Mice
    15. Baicalin, A Metabolite Of Baicalein With Antiviral Activity Against Dengue virus
    16. Biological Properties Of Baicalein In Cardiovascular System
    17. Combination Effects Of Baicalein With Antibiotics Against Oral Pathogens
    18. Deep Sequencing Of The Scutellaria Baicalensis Georgi Transcriptome Reveals Flavonoid Biosynthetic Profiling And Organ-Specific Gene Expression
    19. Different Effects Of Baicalein, Baicalin And Wogonin On Mitochondrial Function, Glutathione Content And Cell Cycle Progression In Human Hepatoma Cell Lines
    20. Differential Antiviral And Anti-Inflammatory Mechanisms Of The Flavonoids Biochanin A And Baicalein In H5N1 Influenza A virus -Infected Cells
    21. Endothelium-Dependent Contraction And Direct Relaxation Induced By Baicalein In Rat Mesenteric Artery
    22. Free Radical Scavenging And Antioxidant Activities Of Flavonoids Extracted From The Radix Of Scutellaria Baicalensis Georgi
    23. Isolation And Purification Of Baicalein, Wogonin And Oroxylin A From The Medicinal Plant Scutellaria Baicalensis By High-Speed Counter-Current Chromatography
    24. Neuroprotective Effect Of Baicalein Against Mptp Neurotoxicity: Behavioral, Biochemical And Immunohistochemical Profile
    25. New Therapeutic Aspects Of Flavones: The Anticancer Properties Of Scutellaria And Its Main Active Constituents Wogonin, Baicalein And Baicalin
    26. Novel Antiviral Activity Of Baicalein Against Dengue virus
    27. Pharmacokinetics Of Baicalein, Baicalin And Wogonin After Oral Administration Of A Standardized Extract Ofscutellaria Baicalensis, Pf-2405 In Rats
    28. Protective Effects Of Flavonoids In The Roots Of Scutellaria Baicalensis Georgi Against Hydrogen Peroxide-Induced Oxidative Stress In Hs-Sy5Y Cells
    29. Scutellaria Baicalensis And A Constituent Flavonoid, Baicalein, Attenuate Ritonavir‐Induced Gastrointestinal Side‐Effects
    30. Scutellaria Baicalensis Extract And Baicalein Inhibit Replication Of Sars-Cov-2 And Its 3C-Like Protease In Vitro
    31. Scutellaria Baicalensis, The Golden Herb From The Garden Of Chinese Medicinal Plants
    32. Separation Methods Used For Scutellaria Baicalensis Active Components
    33. Study Of The Chemical Composition And Antimicrobial Activities Of Ethanolic Extracts From Roots Of Scutellaria Baicalensis Georgi
    34. Synthesis And Biological Evaluation Of Baicalein Derivatives As Potent Antitumor Agents
    35. The Anti-Inflammatory Activity Of Scutellaria Rivularis Extracts And Its Active Components, Baicalin, Baicalein And Wogonin
    36. The Baikal Scullcap (Scutellaria Baicalensis Georgi)–A Potential Source Of New Drugs
    37. The Fascinating Effects Of Baicalein On Cancer: A Review
    38. The Stimulatory Activities Of Baicalein And Baicalin Compounds Derived From Scutellaria Baicalensis On Insulin Secretion In Vitro
    39. Therapeutic Potentials Of Baicalin And Its Aglycone, Baicalein Against Inflammatory Disorders

    benzaldehyde
    (Laurus nobilis leaves)

    1. Cytotoxicity And Antiviral Activity Of Palladium (Ii) And Platinum (Ii) Complexes With 2-(Diphenylphosphino) Benzaldehyde 1-Adamantoylhydrazone
    2. Hydrogen Bonds And Antiviral Activity Of Benzaldehyde Derivatives
    3. Substituted Benzaldehyde Thiosemicarbazone With Antiviral Activity Against Poliovirus .

    Berberine
    (Coptis chinensis extract)

    1. Antiviral Activity Of Berberine
    2. Antiviral Activity Of Berberine And Related Compounds Against Human Cytomegalovirus
    3. Assessment Of The Embryotoxicity Of Four Chinese Herbal Extracts Using The Embryonic Stem Cell Test
    4. Coptis Chinensis
    5. Electrospinning Fabrication Of Poly (Vinyl Alcohol)/Coptis Chinensis Extract Nanofibers For Antimicrobial Exploits
    6. In Vitro Antiviral Activity Of A Berberine Derivant Hb-13 Against Herpes Simplex virus
    7. In Vivo And In Vitro Antiviral Effects Of Berberine On Influenza virus
    8. Research Of Antiviral Mechanisms Of Action Of Berberine Derivate Hb-13 Against Herpes Simplex virus Type 2 [J]
    9. Synthesis And Biological Evaluation Of Berberine Derivatives As A New Class Of Broad-Spectrum Antiviral Agents Against Coxsackievirus B
    10. Synthesis And Evolution Of Berberine Derivatives As A New Class Of Antiviral Agents Against Enterovirus 71 Through The Mek/Erk Pathway And Autophagy
    11. The Antiviral Alkaloid Berberine Ameliorates Neuropathic Pain In Rats With Peripheral Nerve Injury
    12. The Antiviral Alkaloid Berberine Reduces Chikungunya virus -Induced Mitogen-Activated Protein Kinase Signaling

    Beta-sitosterol
    (Rice bran oil)

    1. 4 Other Important
    2. Are Logicol And Proactive Are Rip-Off?
    3. Food Industry Waste: Mine Of Nutraceuticals
    4. Hibiscus Sabdariffa
    5. Lesson No. 26 Heena (Mehndi)
    6. Phytochemicals As Bioactive Agents
    7. Plant Estrogens
    8. Safety Evaluation Of Supercritical Carbon Dioxide Extract Of Aloe Vera Gel
    9. The Importance Of Sitosterol And Sitosterolin In Human And Animal Nutrition
    10. β-sitosterol ameliorates influenza A virus -induced proinflammatory response and acute lung injury in mice by disrupting the cross-talk between RIG-I and IFN/STAT signaling
    11. Suppression of hepatitis B virus-derived human hepatocellular carcinoma by NF-κB-inducing kinase-specific siRNA using liver-targeting liposome
    12. Immune Modulation and Anti-HIV Effect

    BS has been shown to act as a powerful immune modulator []. BS exhibits immune-modulating activities in HIV-infected patients []. It has also been reported that BS targets specific T-helper (Th) lymphocytes, increasing Th1 activity and improving T-lymphocyte and natural killer (NK) cell activity [,]. In another study it was observed that BS maintains stable CD 4 cell counts in AIDS, declines apoptosis of CD 4 lymphocytes slightly, thereby slowing HIV. A significant decrease in IL-6 levels in the same study leads to a further claim that there is slowing down of viral replication rates in infected cells thereby decreasing viral load []. Neurath et al. (2005) proposes BS as an envelope virus neutralizing compound (EVNC) and thus acting as an HIV-1 entry inhibitor []. This claim has been substantiated by the fact that the EVNCs in the body fluid neutralize viruses in the blood stream and elicit an immune response to the neutralized authentically folded virus particle [,]. Even though the effect of BS on entry and exit out of the cell is not available, it is evident that BS facilitates the development of a potentially protective immunity against HIV. However, further study for considering BS as potential therapeutic agent has not progressed. Therefore, extensive study is suggested.

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    Betulinic acid
    (Betula platyphylla Suk bark)

    1. Analysis Of Three Types Of Triterpenoids In Tetraploid White Birches (Betula Platyphylla Suk.) And Selection Of Plus Trees
    2. Anti-Aids Agents. 78. Design, Synthesis, Metabolic Stability Assessment, And Antiviral Evaluation Of Novel Betulinic Acid Derivatives As Potent Anti-Human …
    3. Extraction Of Phytochemicals Betulin And Betulinic Acid From The Chaga Mushroom And Their Effect On Mcf-7 Cells
    4. Ionic Derivatives Of Betulinic Acid Exhibit Antiviral Activity Against Herpes Simplex virus Type-2 (Hsv-2), But Not Hiv-1 Reverse Transcriptase
    5. Parameter Optimization And Potential Bioactivity Evaluation Of A Betulin Extract From White Birch Bark
    6. Synthesis And Antiviral Activity Of Hydrazides And Substituted Benzalhydrazides Of Betulinic Acid And Its Derivatives
    7. Synthesis And Antiviral Activity Of Ureides And Carbamates Of Betulinic Acid And Its Derivatives
    8. Synthesis Of New Betulinic Acid/Betulin-Derived Dimers And Hybrids With Potent Antimalarial And Antiviral Activities

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    Bisdemethoxycurcumin
    (Turmeric rhizome extract)

    1. Bioefficacy Of Turmeric Rhizome Extracts With Alum On Microbes: An In Vitro Approach
    2. Effects Of Dietary Supplementation With Turmeric Rhizome Extract On Growth Performance, Carcass Characteristics, Antioxidant Capability, And Meat Quality Of Wenchang …
    3. Effects Of Neem, Turmeric And Papaya Leaf Extract Mixture On Growth Performance Of Broilers
    4. Pros And Cons Of Curcumin As Bioactive Phyto-Compound For Effective Management Of Insect Pests
    5. Werayut Pothițirat’*, Sundari Desi Nuryanti “, Phatsawee Jansook”, Kingkan Sanpanya’And Wandee Gritsanapan

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    Brachyamide B
    (Piper boehmeriaefolium (Miq.) C. DC)

    1. A Review Of The Literature And Latest Advances In Research Of Piper Sarmentosum
    2. A Review On Diversified Use Of The King Of Spices: Piper Nigrum (Black Pepper)
    3. Lc-Ms Analysis Of Phytocomponents In The Methanol Extract Of Piper Sarmentosum Leaves
    4. Review On Kukkiladhi Choornam Used In Traditional Medicine And Research Activities

     

     

     

    Broussonetia papyrifera

    1. Identification of polyphenols from Broussonetia papyrifera as SARS CoV-2 main protease inhibitors using in silico docking and molecular dynamics simulation approaches

     

     

     

    bulbocapnine
    (Corydalis decumbens(Thunb.) )

    1. Anticataleptic Actions Of Amantadine Hydroehloride
    2. Anti-Hepatitis B Activity Of Isoquinoline Alkaloids Of Plant Origin
    3. Antiviral And Antimicrobial Evaluation Of Some Heterocyclic Compounds From Turkish Plants
    4. Antiviral And Antimicrobial Profiles Of Selected Isoquinoline Alkaloids From Fumaria And Corydalis Species
    5. Biologically Active Isoquinoline Alkaloids With Drug-Like Properties From The Genus Corydalis
    6. Cytotoxic And Antitumor Potentialities Of Aporphinoid Alkaloids
    7. Cytotoxicity, Antiviral And Antimicrobial Activities Of Alkaloids, Flavonoids, And Phenolic Acids
    8. Natural Antiviral Compounds
    9. New Skeletons And New Concepts In Amaryllidaceae Alkaloids

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    caffeic acid
    (Cimicifuga simplex (DC.) Wormsk. ex Turcz.root)

    1. Anti-Hiv Activities Of Natural Antioxidant Caffeic Acid Derivatives: Toward An Antiviral Supplementation Diet
    2. Antioxidant, Antibacterial, And Antiviral Effects Of Two Essential Oils, Their Components, And Caffeic Acid For Use As Feed Additives In Poultry
    3. Antiviral Activity Of Enzymatically Oxidized Caffeic Acid Against Herpesvirus Hominis Type 1 And Type 2.
    4. Antiviral Activity Of Metal Chelates Of Caffeic Acid And Similar Compounds Towards Herpes Simplex, Vsv-Ebola Pseudotyped And Vaccinia virus es
    5. Antiviral Properties Of Caffeic Acid Phenethyl Ester And Its Potential Application
    6. Caffeic Acid Inhibits Hcv Replication Via Induction Of Ifnα Antiviral Response Through P62-Mediated Keap1/Nrf2 Signaling Pathway
    7. Caffeic Acid Oligomers From Mesona Chinensis And Their In Vitro Antiviral Activities
    8. In Vitro Antiviral Efficacy Of Caffeic Acid Against Canine Distemper virus

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    Calanolide A
    (Calophyllum lanigerum)

    1. An Efficient And Scalable Method For The Isolation Of Costatolide, A Naturally-Occurring Anti-Hiv Agent, From The Latex Of Calophyllum Teysmannii Var. Inophylloide
    2. Anti-Hiv-1 Activity Of Calanolides Used In Combination With Other Mechanistically Diverse Inhibitors Of Hiv-1 Replication
    3. Antiviral Activity And Mechanism Of Action Of Calanolide A Against The Human Immunodeficiency virus Type-1.
    4. Calanolide A New Non-Nucleoside Reverse Transcriptase Inhibitor (Nnrti): A Review
    5. Chemical Library And Structure–Activity Relationships Of 11-Demethyl-12-Oxo Calanolide A Analogues As Anti-Hiv-1 Agents
    6. Concise Synthesis Of Anti-Hiv-1 Active (+)-Inophyllum B And (+)-Calanolide A By Application Of (−)-Quinine-Catalyzed Intramolecular Oxo-Michael Addition
    7. Current Lead Natural Products For The Chemotherapy Of Human Immunodeficiency virus (Hiv) Infection
    8. Highly Suppressing Wild-Type Hiv-1 And Y181C Mutant Hiv-1 Strains By 10-Chloromethyl-11-Demethyl-12-Oxo-Calanolide A With Druggable Profile
    9. Hiv Inhibitory Natural Products. Part 7. The Calanolides, A Novel Hiv-Inhibitory Class Of Coumarin Derivatives From The Tropical Rainforest Tree, Calophyllum Lanigerum
    10. Hiv Reverse Transcriptase Inhibitors Of Natural Origin
    11. Hiv-1 Inhibitory Compounds From Calophyllum Brasiliense Leaves
    12. Hiv-Inhibitory Coumarins From Latex Of The Tropical Rainforest Tree Calophyllum Teysmannii Var. Inophylloide
    13. Kinetic Analysis Of Inhibition Of Human Immunodeficiency virus Type-1 Reverse Transcriptase By Calanolide A.
    14. Pharmaceutical Properties Of Related Calanolide Compounds With Activity Against Human Immunodeficiency virus
    15. Plant Derived Antivirals: A Potential Source Of Drug Development
    16. Preclinical Investigation Of The Anti-Hiv Activity Of Calanolide A. Characterization Of The Nature Of Calanolide A As A Novel Reverse Transcriptase Inhibitor.
    17. Pyranocoumarins From Tropical Species Of The Genus Calophyllum:  A Chemotaxonomic Study Of Extracts In The National Cancer Institute Collection
    18. Review On Natural Coumarin Lead Compounds For Their Pharmacological Activity
    19. Safety And Pharmacokinetic Profile Of Multiple Escalating Doses Of (+)-Calanolide A, A Naturally Occurring Nonnucleoside Reverse Transcriptase Inhibitor, In Healthy Hiv …
    20. Sensitivity And Resistance To (+)-Calanolide A Of Wild-Type And Mutated Forms Of Hiv-1 Reverse Transcriptase
    21. Specific Inhibition Of The Reverse Transcriptase Of Human Immunodeficiency virus Type 1 And The Chimeric Enzymes Of Human Immunodeficiency virus Type 1 And Type 2 …
    22. Structural Analogues Of The Calanolide Anti-Hiv Agents. Modification Of The Trans-10,11-Dimethyldihydropyran-12-Ol Ring (Ring C)
    23. Structure−Activity Modifications Of The Hiv-1 Inhibitors (+)-Calanolide A And (−)-Calanolide B
    24. Synthesis, Chromatographic Resolution, And Anti-Human Immunodeficiency virus Activity Of (±)-Calanolide A And Its Enantiomers

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    Campesterol
    (Rapeseed oil)

    1. Anti-Aging
    2. Anti-Aging Serum
    3. Aromaticstudies. Com
    4. Balanced, Progressive & Inspiring Education For A New Generation Of Aromatherapists.
    5. Date Seeds: A Promising Source Of Oil With Functional Properties
    6. Evaluation Of Balanitesaegyptiaca Oil As Untraditional Source Of Oil And Its Anti-Inflammatory Activity
    7. Inhibitory Effects Of Grape Seeds Powder, Extract And Oil On Gentamicin Induced Nephrotoxicity In Rats
    8. Natural Skin Care Serum
    9. Potential Benefits Of Jujube (Zizyphus Lotus L.) Bioactive Compounds For Nutrition And Health
    10. Prickly Pear Seed Oil Benefits On The Skin
    11. Prickly Pear Serum
    12. Pumpkin (Cucurbita Pepo L.) Seed Oil
    13. Valorization Of Fruits By-Products To Unconventional Sources Of Additives, Oil, Biomolecules And Innovative Functional Foods
    14. Plant sterols: functional lipids in immune functionand inflammation?

    Carvacrol
    (Oregano)

    Antiviral activity of the Lippia graveolens (Mexican oregano) essential oil and its main compound carvacrol against human and animal viruses

    Mexican oregano (Lippia graveolens) is a plant found in Mexico and Central America that is traditionally used as a medicinal herb. In the present study, we investigated the antiviral activity of the essential oil of Mexican oregano and its major component, carvacrol, against different human and animal viruses. The MTT test (3–4,5-dimethythiazol-2yl)-2,5-diphenyl tetrazolium bromide) was conducted to determine the selectivity index (SI) of the essential oil, which was equal to 13.1, 7.4, 10.8, 9.7, and 7.2 for acyclovir-resistant herpes simplex virus type 1 (ACVR-HHV-1), acyclovir-sensitive HHV-1, human respiratory syncytial virus (HRSV), bovine herpesvirus type 2 (BoHV-2), and bovine viral diarrhoea virus (BVDV), respectively. The human rotavirus (RV) and BoHV-1 and 5 were not inhibited by the essential oil. Carvacrol alone exhibited high antiviral activity against RV with a SI of 33, but it was less efficient than the oil for the other viruses. Thus, Mexican oregano oil and its main component, carvacrol, are able to inhibit different human and animal viruses in vitro. Specifically, the antiviral effects of Mexican oregano oil on ACVR-HHV-1 and HRSV and of carvacrol on RV justify more detailed studies.

     


    Chavicine
    (black pepper)

    1. A Review On Different Sources Of Piper Nigrum L. Adulterants
    2. A Review On Diversified Use Of The King Of Spices: Piper Nigrum (Black Pepper)
    3. An Exploration Of Significant Curative Spices: A
    4. Antiradical Properties Of Essential Oils And Extracts From Coriander, Cardamom, White, Red, And Black Peppers
    5. Isolation Of Piperdine From Piper Nigrum And Its Antiproliferative Activity
    6. Phytochemicals From The Bark Of Rhamnus Caroliniana
    7. Piperine: A Comprehensive Review Of Methods Of Isolation, Purification And Biological Properties
    8. Postharvest Processing And Benefits Of Black Pepper, Coriander, Cinnamon, Fenugreek, And Turmeric Spices
    9. Quantitative Structure–Cytotoxicity Relationship Of Newly Synthesized Piperic Acid Esters
    10. Quantitative Structure–Cytotoxicity Relationship Of Piperic Acid Amides
    11. Review On Kukkiladhi Choornam Used In Traditional Medicine And Research Activities
    12. Role Of Spices In Preventing Chronic Problems: A Review
    13. Therapeutic Actions & Potentials Of Black Pepper
    14. Traditional Chinese Functional Foods
    15. Trikatu-A Combination Of Three Bioavailability Enhancers
    16. Why Spices Are Unique?
    17. World Journal Of Pharmaceutical And Life Sciences Wjpls

    chelidimerine
    (Chelidonium majus)

    1. Chelidonium Majus L.(Greater Celandine)–A Review On Its Phytochemical And Therapeutic Perspectives
    2. Suppressive Effects Of Chelidonium Majus Methanol Extract In Knee Joint, Regional Lymph Nodes, And Spleen On Collagen-Induced Arthritis In Mice

    chlorogenic acid
    (Green coffee bean extract)

    1. And Vasodilator Effects Of Methanolic Extract Of Inula Viscosa: Biological Evaluation And Pom Analysis Of Cynarin, Chlorogenic Acid As Potential Hypertensive
    2. Anti-Hepatitis B virus Activity Of Chlorogenic Acid And Its Related Compounds
    3. Antiviral Activity Of Chlorogenic Acid Against Influenza A (H1N1/H3N2) virus And Its Inhibition Of Neuraminidase
    4. Bioactivity Of Fermented Green Coffee Bean Extract Containing High Chlorogenic Acid And Surfactin
    5. Chlorogenic Acid (Cga): A Pharmacological Review And Call For Further Research
    6. Coffee Consumption And Coronary Heart Diseases: A Mini-Review
    7. Consumption Of Green Coffee And The Risk Of Chronic Diseases
    8. Determination Of Antibacterial Activity Of Green Coffee Bean Extract On Periodontogenic Bacteria Like Porphyromonas Gingivalis, Prevotella Intermedia …
    9. Effect Of Green Coffee Bean Extract On Streptococcus Mutans Count: A Randomised Control Trial
    10. Effect Of Green Coffee Beans Extract Ointments For Wound Healing
    11. Effect Of Kombucha Culture On Caffeine And Chlorogenic Acid Content In Fermentation Of Robusta Green Coffee Beans …
    12. Effect Of Silymarin Versus Silymarin And Green Coffee Extract On Thioacetamide Induced Liver Injury In Adult Male Albino Rats (Histological And Immunohistochemical …
    13. Emergency Antiviral Drug Discovery During A Pandemic-A Case Study On The Application Of Natural Compounds To Treat Covid-19
    14. Enter Stage Right Chlorogenic Acid
    15. Extraction Of Chlorogenic Acid From Chinese Herbal Medicine And Its Antiviral Effect On Porcine Parvovirus In Vitro [J]
    16. Fermentation Of Green Coffee Bean (Coffee Arabica) With Lactic Acid Bacteria And Characterization Of Its Biochemical Properties
    17. Identifying Anti-Hsv Compounds From Unrelated Plants Using Nmr And Lc–Ms Metabolomic Analysis
    18. Safety And Efficacy Of Banaba–Moringa Oleifera–Green Coffee Bean Extracts And Vitamin D3 In A Sustained Release Weight Management Supplement
    19. Salting-Out Gradients In Centrifugal Partition Chromatography For The Isolation Of Chlorogenic Acids From Green Coffee Beans
    20. Studies On Antiviral Effect Of Chlorogenic Acid On Prrsv In Vitro
    21. To Evaluate The Antimicrobial Efficacy Of Green Coffee Bean Extract On Periopathogens-A Clinico-Microbiological Study.

    Chrysin
    (Pinus mon-ticola Dougl)

    1. Alleviation Of Doxorubicin-Induced Nephrotoxicity And Hepatotoxicity By Chrysin In Wistar Rats
    2. An Efficient Synthesis Of Chrysin
    3. An Overview On Immunoregulatory And Anti-Inflammatory Properties Of Chrysin And Flavonoids Substances
    4. Anti-Enterovirus 71 Effects Of Chrysin And Its Phosphate Ester
    5. Antiherpetic Activities Of Flavonoids Against Herpes Simplex virus Type 1 (Hsv-1) And Type 2 (Hsv-2)In Vitro
    6. Antinociceptive Effect Of Chrysin In Diabetic Neuropathy And Formalin-Induced Pain Models
    7. Antitumor Properties Of A Vanadyl (Iv) Complex With The Flavonoid Chrysin [Vo (Chrysin) 2 Etoh] 2 In A Human Osteosarcoma Model: The Role Of Oxidative Stress And …
    8. Antiviral Activity And Mode Of Action Of Propolis Extracts And Selected Compounds
    9. Antiviral Activity Of Chrysin Derivatives Against Coxsackievirus B3 In Vitro And In Vivo
    10. Antiviral Activity Of Silymarin Against Chikungunya virus
    11. Apigenin, Chrysin, And Luteolin Selectively Inhibit Chymotrypsin-Like And Trypsin-Like Proteasome Catalytic Activities In Tumor Cells
    12. Application Of Visible And Near Infrared Spectroscopy For Rapid Analysis Of Chrysin And Galangin In Chinese Propolis
    13. Behavioral Characterisation Of The Flavonoids Apigenin And Chrysin
    14. Beneficial Effects Of Chrysin On The Reproductive System Of Adult Male Rats
    15. Chemopreventive And Therapeutic Potential Of Chrysin In Cancer: Mechanistic Perspectives
    16. Chrysin Cocrystals: Characterization And Evaluation
    17. Chrysin Enhances Sensitivity Of Bel-7402/Adm Cells To Doxorubicin By Suppressing Pi3K/Akt/Nrf2 And Erk/Nrf2 Pathway
    18. Chrysin Functionalized Nhc–Au (I) Complexes: Synthesis, Characterization And Effects On The Nematode Caenorhabditis Elegans
    19. Chrysin Increases The Therapeutic Efficacy Of Docetaxel And Mitigates Docetaxel-Induced Edema
    20. Chrysin Rich Scutellaria Discolor Colebr. Induces Cervical Cancer Cell Death Via The Induction Of Cell Cycle Arrest And Caspase-Dependent Apoptosis
    21. Chrysin, A Flavonoid Attenuates Histological Changes Of Hyperammonemic Rats: A Dose Dependent Study
    22. Chrysin, A Natural And Biologically Active Flavonoid, Influences A Murine Leukemia Model In Vivo Through Enhancing Populations Of T-And B-Cells, And Promoting …
    23. Chrysin, Abundant In Morinda Citrifolia Fruit Water–Etoac Extracts, Combined With Apigenin Synergistically Induced Apoptosis And Inhibited Migration In Human …
    24. Chrysin: A Histone Deacetylase 8 Inhibitor With Anticancer Activity And A Suitable Candidate For The Standardization Of Chinese Propolis
    25. Chrysin: Is It An Effective Aromatase Inhibitor
    26. Chrysin: Sources, Beneficial Pharmacological Activities, And Molecular Mechanism Of Action
    27. Chrysin-Piperazine Conjugates As Antioxidant And Anticancer Agents
    28. Computational Studies Of The Binding Mechanism Of Calmodulin With Chrysin
    29. Constituents Of Propolis: Chrysin, Caffeic Acid, P-Coumaric Acid, And Ferulic Acid Induce Prodh/Pox-Dependent Apoptosis In Human Tongue Squamous Cell …
    30. Convergent Synthesis Of Moslosooflavone, Isowogonin And Norwogonin From Chrysin
    31. Design, Synthesis And Biological Evaluation Of Chrysin Benzimidazole Derivatives As Potential Anticancer Agents
    32. Development Of Novel N-Isopropylacrylamide (Nipaam) Based Hydrogels With Varying Content Of Chrysin Multiacrylate
    33. Effects Of Chrysin On Urinary Testosterone Levels In Human Males
    34. Effects Of Chrysin, Apigenin, Genistein And Their Homoleptic Copper (Ii) Complexes On The Growth And Metastatic Potential Of Cancer Cells
    35. Effects Of The Flavonoid Chrysin On Nitrofurantoin Pharmacokinetics In Rats: Potential Involvement Of Abcg2
    36. Egyptian Propolis: 2. Chemical Composition, Antiviral And Antimicrobial Activities Of East Nile Delta Propolis
    37. Ethanolic Extract Of Propolis, Chrysin, Cape Inhibit Human Astroglia Cells
    38. Evaluation Of The Mutagenic Activity Of Chrysin, A Flavonoid Inhibitor Of The Aromatization Process
    39. First And Second Derivative Spectrophotometric Determination Of Flavonoids Chrysin And Quercetin
    40. Flavonoids Chrysin And Benzoflavone, Potent Breast Cancer Resistance Protein Inhibitors, Have No Significant Effect On Topotecan Pharmacokinetics In Rats Or Mdr1A/1B …
    41. Fluorine-Containing Chrysin Derivatives: Synthesis And Biological Activity
    42. Identifying Novel Antiviral Targets Against Enterovirus 71: Where Are We?
    43. Improved Chemotherapeutic Efficacy Of Injectable Chrysin Encapsulated By Copolymer Nanoparticles
    44. In Vitro Antiviral Activity Of Propolis
    45. Influence Of Chrysin On Hepatic Marker Enzymes And Lipid Profile Against D-Galactosamine-Induced Hepatotoxicity Rats
    46. Inhibition Of Dengue virus Replication By Diisopropyl Chrysin-7-Yl Phosphate
    47. Nephroprotective Efficacy Of Chrysin Against Cisplatin‐Induced Toxicity Via Attenuation Of Oxidative Stress
    48. Optimization Of Ultrasound-Assisted Extraction Of Quercetin, Luteolin, Apigenin, Pinocembrin And Chrysin From Flos Populi By Plackett-Burman Design Combined …
    49. Phytochemistry Chrysin: Sources, Bene Fi Cial Pharmacological Activities, And Molecular Mechanism Of Action
    50. Probing The Origins Of Anticancer Activity Of Chrysin Derivatives
    51. Protective Effects Of Chinese Propolis And Its Component, Chrysin, Against Neuronal Cell Death Via Inhibition Of Mitochondrial Apoptosis Pathway In Sh-Sy5Y Cells
    52. Quantification Of Baicalein, Chrysin, Biochanin-A And Ellagic Acid In Root Bark Of Oroxylum Indicum By Rp-Hplc With Uv Detection
    53. Research Progress Of Chrysin Derivatives With Potential Biological Activities
    54. Role Of Oxidative Stress In The Antitumoral Action Of A New Vanadyl (Iv) Complex With The Flavonoid Chrysin In Two Osteoblast Cell Lines: Relationship With The …
    55. Simultaneous Determination Of Baicalin, Wogonoside, Baicalein, Wogonin, Oroxylin A And Chrysin Of Radix Scutellariae Extract In Rat Plasma By Liquid Chromatography …
    56. Spectroscopic And Thermodynamic Study Of Chrysin And Quercetin Complexes With Cu (Ii)
    57. Synergistic Effect Of Free And Nano-Encapsulated Chrysin-Curcumin On Inhibition Of Htert Gene Expression In Sw480 Colorectal Cancer Cell Line
    58. Synthesis And Evaluation Of Antitumour Activity In Vitro And In Vivo Of Chrysin Salicylate Derivatives
    59. Synthesis And Molecular Docking Studies Of Chrysin Derivatives As Antibacterial Agents
    60. Synthesis Of New Types Of N‐Arylpiperazine Phosphoramide Analogues Of Chrysin
    61. Synthesis Of The Novel Phosphoramidate Derivatives Of Chrysin
    62. Synthesis, Structural Study And Biological Activity Of New Derivatives Of Chrysin Containing A 2-Mercaptopyridyl Or 5-(Trifluoromethyl)-2-Mercaptopyridyl Fragments
    63. Synthetic Derivatives Of Chrysin And Their Biological Activities
    64. The Caffeoylics As A New Family Of Natural Antiviral Compounds
    65. The Dependence On Ionic Strength Of The Protonation Of Water-Insoluble Flavonoids Chrysin And Daidzein In Naclo4 Non-Aqueous Solutions
    66. The Nature Of Phosphorylated Chrysin− Protein Interactions Involved In Noncovalent Complex Formation By Electrospray Ionization Mass Spectroscopy
    67. The O-Methylation Of Chrysin Markedly Improves Its Intestinal Anti-Inflammatory Properties: Structure–Activity Relationships Of Flavones
    68. The Relationship Between Pharmacological Properties And Structure-Activity Of Chrysin Derivatives

    cinanserin
    (cinnamic acid)

    1. Cinnamate Hybrids: A Unique Family Of Compounds With Multiple Biological Activities
    2. Evaluation Of Antiviral Activities Of Houttuynia Cordata Thunb. Extract, Quercetin, Quercetrin And Cinanserin On Murine Coronavirus And Dengue virus Infection
    3. Host Modulation Of Resistance To Infection And Neoplasia
    4. Insights Into The Mechanism Of Antiproliferative Effects Of Primaquine-Cinnamic Acid Conjugates On Mcf-7 Cells
    5. Phytochemical Profile And In Vitro Evaluation Of Extracts From Leaves Of Drimys Brasiliensis (Winteraceae) Against Bovine And Equine Herpesvirus es
    6. Synthesis And Structure-Activity Relationship Studies Of Parthenolide Derivatives As Potential Anti-Triple Negative Breast Cancer Agents

    Cinnamomum cassia Presl
    extract
    (Cinnamomum cassia Presl Dried bark)

    1. Activities Of Korean Medicinal Herbs And Traditional Prescriptions Against Herpes Simplex virus Type-1
    2. Analysis Of The Volatile Organic Compounds In Cinnamomum Cassia Bark By Direct Sample Introduction Thermal Desorption Gas Chromatography–Mass Spectrometry
    3. Anti-Tmv Mechanism Of Volatile Oil Extracted From Allium Satuvum L.[J]
    4. Aroma Profile Of Folium Isatidis Leaf As A Raw Material Of Making Bingqu For Chixiang Aroma- And Flavor-Type Baijiu
    5. Chinese Liver Balance Tcm Conc.(30 Caps)
    6. Cinnamomum Cassia Presl: A Review Of Its Traditional Uses, Phytochemistry, Pharmacology And Toxicology
    7. Content Determination Of The Major Constituents Of Yinchenzhufu Decoction Via Ultra High-Performance Liquid Chromatography Coupled With Electrospray Ionisation …
    8. Development Of An Ionic Liquid-Based Microwave-Assisted Method For Simultaneous Extraction And Distillation For Determination Of Proanthocyanidins And Essential Oil …
    9. Endophytic Actinomycetes Associated With Cinnamomum Cassia Presl In Hoa Binh Province, Vietnam: Distribution, Antimicrobial Activity And, Genetic Features
    10. Magnolol And Honokiol From Magnolia Officinalis Enhanced Antiviral Immune Responses Against Grass Carp Reovirus In Ctenopharyngodon Idella Kidney Cells
    11. Serum Pharmacological Study Of Oleum Cinnamomi On Coxsackievirus B_3 [J]
    12. The Antiadenovirus Activities Of Cinnamaldehyde In Vitro
    13. The Combined Therapy Of A Traditional Chinese Medicine Formula And Western Medicine For A Critically Ill Case Infected With Covid-19
    14. Therapeutic And Pharmaceutical Potential Of Cinnamomum Tamala

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    Cirsilineol
    (Cirsium lineare (Thunb.) Sch.)

    1. Antiviral Agents Of Plant Origin. Antiherpetic Activity Of Acacetin
    2. Small Molecule Inhibitors Of Epithelial‐Mesenchymal Transition For The Treatment Of Cancer And Fibrosis
    3. The Protection Of Thymus Vulgaris Leaves Alcoholic Extract Against Hepatotoxicity Of Alcohol In Rats

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    Cirsimaritin
    (Rabdosia eriocalyx extract)

    1. Antiviral Activity Of Natural Occurring Flavonoids In Vitro
    2. Cirsimaritin Inhibits Influenza A virus Replication By Downregulating The Nf-Κb Signal Transduction Pathway
    3. Cirsimaritin, A Lung Squamous Carcinoma Cells (Ncih-520) Proliferation Inhibitor
    4. Effects Of Cirsimaritin, A Flavone Isolated From Artemisia Judaica, On Isolated Guinea-Pig Ileum
    5. Effects Of Selected Flavonoids On Deformability, Osmotic Fragility And Aggregation Of Human Erythrocytes
    6. Seasonal Variation Of Free Flavone Aglycones From Sideritis Leucantha (Lamiaceae)

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    cis-capsaicin
    (civamide)

    1. Civamide (Cis-Capsaicin) For Treatment Of Primary Or Recurrent Experimental Genital Herpes
    2. Cytotoxicity, Antiviral And Antimicrobial Activities Of Alkaloids, Flavonoids, And Phenolic Acids
    3. Herpes Simplex virus : Drug Resistance And New Treatment Options Using Natural Products
    4. Pharmacological Importance Of An Ethnobotanical Plant: Capsicum Annuum L.

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    colchicine
    (Colchicum autumnale L.)

    1. An Overview Of Tubulin Inhibitors That Interact With The Colchicine Binding Site
    2. Colchicine–An Overview For Plant Biotechnologists
    3. Cytotoxicity, Antiviral And Antimicrobial Activities Of Alkaloids, Flavonoids, And Phenolic Acids
    4. Effects Of Mineral Nutrients On Physiological And Biochemical Processes Related To Secondary Metabolites Production In Medicinal Herbs
    5. Investigation Of Morphological And Anatomical Changes In Catharanthus Roseus (L.) G. Don Due To Colchicine Induced Polyploidy
    6. Morphological, Physiological, Cytological And Phytochemical Studies In Diploid And Colchicine-Induced Tetraploid Plants Of Echinacea Purpurea (L.)
    7. Plant-Derived Natural Product Research Aimed At New Drug Discovery
    8. Sensitive Detection Of Colchicine At A Glassy Carbon Electrode Modified With Magnetic Ionic Liquid/Cuo Nanoparticles/Carbon Nanofibers In Pharmaceutical And Plasma …
    9. Study Of The Mechanism Of Liver Injury Induced By Colchicin [J]
    10. Synthesis, Biological Evaluation, And Molecular Docking Of Combretastatin And Colchicine Derivatives And Their Hce1‐Activated Prodrugs As Antiviral Agents
    11. Tcm-Based New Drug Discovery And Development In China
    12. The Value Of Plants Used In Traditional Medicine For Drug Discovery.
    13. Topical Herbal Remedies For Treatment Of Joint Pain According To Iranian Traditional Medicine
    14. Tubulin Inhibitors Targeting The Colchicine Binding Site: A Perspective Of Privileged Structures

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    Cordifolioside A
    (Viola verecunda extract)

    1. A Review On Rasayana
    2. Antiviral Compound Screening, Peptide Designing, And Protein Network Construction Of Influenza A virus (Strain A/Puerto Rico/8/1934 H1N1)
    3. Herbal Immunomodulators-A Remedial Panacea For Designing And Developing Effective Drugs And Medicines: Current Scenario And Future Prospects
    4. Herbal Immunomodulors: A Review
    5. Identification Of Bio-Active Components In Leaf Extracts Of Aloe Vera, Ocimum Tenuiflorum (Tulasi) And Tinospora Cordifolia (Amrutballi)
    6. Indian Traditional Ayurvedic Treatment Regime For Novel Coronavirus , Covid-19
    7. Pharmacological Potential Of Tinospora Cordifolia (Willd.) Miers Ex Hook. & Thoms.(Giloy): A Review
    8. Prevention Of Hepatotoxicity Due To Anti Tuberculosis Treatment: A Novel Integrative Approach
    9. Review On Pharmacological Profile Of Medicinal Vine: Tinospora Cordifolia
    10. Tinospora Cordifolia: Ethnobotany, Phytopharmacology And Phytochemistry Aspects

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    Crategolic acid
    (Loquat leaf extract)

    1. Anti-Inflammatory Actions Of Pentacyclic Triterpenes
    2. Eugenia Caryophyllata Thunberg (Family Myrtaceae): A Review
    3. In Silico Analysis Of Phytochemicals From Clove Against Bronchitis
    4. In Vitro Antiviral Activity Of Plant Extracts On Goatpox virus Replication
    5. Maslinic Acid, A Natural Phytoalexin-Type Triterpene From Olives—A Promising Nutraceutical?
    6. Profile Of Bioactive Compounds In Syzygium Cumini–A Review
    7. Purification And Characterization Of Antiviral Substance From The Bud Of Syzygium Aromatica
    8. Shortlisting Phytochemicals Exhibiting Inhibitory Activity Against Major Proteins Of Sars-Cov-2 Through Virtual Screening

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    Curcumin
    (Turmeric Root Extract)

    1. 3D-Quantitative Structure–Activity Relationship And Antiviral Effects Of Curcumin Derivatives As Potent Inhibitors Of Influenza H1N1 Neuraminidase
    2. A Review On Antibacterial, Antiviral, And Antifungal Activity Of Curcumin
    3. Antiviral Action Of Curcumin Encapsulated In Nanoemulsion Against Four Serotypes Of Dengue virus
    4. Antiviral Activity Of Chitosan Nanoparticles Encapsulating Curcumin Against Hepatitis C virus Genotype 4A In Human Hepatoma Cell Lines
    5. Antiviral Activity Of Curcumin Loaded Milk Proteins Nanoparticles On Potato virus Y.
    6. Antiviral Activity Of Curcumin-Nanoemulsion Associated With Photodynamic Therapy In Vulvar Cell Lines Transducing Different Variants Of Hpv-16
    7. Antiviral And Quantitative Structure Activity Relationship Study For Dihydropyridones Derived From Curcumin.
    8. Antiviral Carbon Dots: High Amplification Of The Antiviral Activity Of Curcumin Through Transformation Into Carbon Quantum Dots (Small 41/2019)
    9. Antiviral Potential Of Curcumin
    10. Co-Encapsulation Of Acyclovir And Curcumin Into Microparticles Improves The Physicochemical Characteristics And Potentiates In Vitro Antiviral Action: Influence Of The …
    11. Correction To Multisite Inhibitors For Enteric Coronavirus : Antiviral Cationic Carbon Dots Based On Curcumin
    12. Curcuma Longa Linn. A Phytochemical And Phytopharmacological Review
    13. Curcumin Against Hepatitis C virus Infection: Spicing Up Antiviral Therapies With ‘Nutraceuticals’?
    14. Curcumin Is An Ape1 Redox Inhibitor And Exhibits An Antiviral Activity Against Kshv Replication And Pathogenesis
    15. Curcumin Shows Antiviral Properties Against Norovirus
    16. Curcumin: Clinical Trial Finds No Antiviral Effect.
    17. Design And Development Of Curcumin Bioconjugates As Antiviral Agents
    18. virus -antiviral-ca”>Erratum: Multisite Inhibitors For Enteric Coronavirus : Antiviral Cationic Carbon Dots Based On Curcumin (Acs Applied Nano Materials (2018) 1: 10 (5451− 5459
    19. Evaluation Of Antiviral Activities Of Curcumin Derivatives Against Hsv-1 In Vero Cell Line
    20. High Amplification Of The Antiviral Activity Of Curcumin Through Transformation Into Carbon Quantum Dots
    21. Inhibitory Effect Of Curcumin On Imp Dehydrogenase, The Target For Anticancer And Antiviral Chemotherapy Agents
    22. Inhibitory Effect Of Herbal Remedies On 12-O-Tetradecanoylphorbol-13-Acetate-Promoted Epstein–Barr virus Early Antigen Activation
    23. Multisite Inhibitors For Enteric Coronavirus : Antiviral Cationic Carbon Dots Based On Curcumin
    24. Nutraceuticals In Gastrointestinal Disorders
    25. Phcog Mag: Plant Review Recent Trends In Curcuma Longa Linn
    26. Synergistic Antiviral Effect Of Curcumin Functionalized Graphene Oxide Against Respiratory Syncytial virus Infection
    27. Synthesis, Antibacterial And Antiviral Properties Of Curcumin Bioconjugates Bearing Dipeptide, Fatty Acids And Folic Acid
    28. The Antiviral Effects Of Curcumin Nanomicelles On The Attachment And Entry Of Hepatitis C virus
    29. The Investigation Of Antiviral Mechanisms Of Chitosan Nanoparticles Encapsulating Curcumin Against Hepatitis C virus Genotype–4A On Human Hepatoma Cell Lines
    30. Turmeric/Curcumin Benefits

    Cycloastragenol
    (Astragalus membranaceus （Fisch.)

    1. A Rapid Method For Sensitive Profiling Of Bioactive Triterpene And Flavonoid From Astragalus Mongholicus And Astragalus Membranaceus By Ultra-Pressure Liquid …
    2. Astragaloside Iv And Cycloastragenol Stimulate The Phosphorylation Of Extracellular Signal-Regulated Protein Kinase In Multiple Cell Types
    3. Astragaloside Iv Derived From Astragalus Membranaceus
    4. Astragalus Membranaceus: A Review Study Of Its Anti-Carcinoma Activities
    5. Biological Active Ingredients Of Traditional Chinese Herb Astragalus Membranaceus On Treatment Of Diabetes: A Systematic Review
    6. Cycloastragenol Is A Potent Telomerase Activator In Neuronal Cells: Implications For Depression Management
    7. Cycloastragenol, A Triterpene Aglycone Derived From Radix Astragali, Suppresses The Accumulation Of Cytoplasmic Lipid Droplet In 3T3-L1 Adipocytes
    8. Cycloastragenol: An Exciting Novel Candidate For Age‑Associated Diseases
    9. Enhanced Astragaloside Production And Transcriptional Responses Of Biosynthetic Genes In Astragalus Membranaceus Hairy Root Cultures By Elicitation With Methyl …
    10. Enzymatic Bioconversion Of Cycloastragenol-6-O-Β-D-Glucoside Into Cycloastragenol By A Novel Recombinant Β-Glucosidase From Phycicoccus Sp. Soil748
    11. Further Saponins And Flavonoids From Astragalus Verrucosus Moris
    12. Microbial Transformation Of The Anti-Aging Agent Cycloastragenol By Mucor Racemosus
    13. Optimization Of Astragalus Membranaceus Hairy Roots Induction And Culture Conditions For Augmentation Production Of Astragalosides
    14. Preventive Effects Of Astragaloside Iv And Its Active Sapogenin Cycloastragenol On Cardiac Fibrosis Of Mice By Inhibiting The Nlrp3 Inflammasome
    15. Smith Degradation, An Efficient Method For The Preparation Of Cycloastragenol From Astragaloside Iv
    16. Terpenoid And Flavonoid Biosynthesis In Astragalus Membranaceus
    17. The Role Of Astragalus Membranaceus As Immunomodulator In Poultry
    18. Triterpene Glycosides From Astragalus Icmadophilus
    19. Uv Elicitation For Promoting Astragaloside Production In Astragalus Membranaceus Hairy Root Cultures With Transcriptional Expression Of Biosynthetic Genes


    Cyclocurcumin
    (Turmeric Root Extract)

    1. A Comparative Assessment Of Quality Of Different Marketed Turmeric Powders
    2. A Docking Simulation Study Of Some Herbal Molecules Against Influenza A virus By Targeting Neuraminidase
    3. A Novel Approach For Overcoming Drug Resistance In Breast Cancer Chemotherapy By Targeting New Synthetic Curcumin Analogues Against Aldehyde …
    4. Antiviral Potential Of Curcumin
    5. Curcuma Longa: A Treasure Of Medicinal Properties
    6. Curcuma Longa: Boon For Health Care System With Its Biomedical Application
    7. Extraction Of Essential Oil From Curcuma Longa
    8. Functional Foods As Source Of Bioactive Principles: Some Marked Examples
    9. Human Papilloma virus 16 E6 Protein As A Target For Curcuminoids, Curcumin Conjugates And Congeners For Chemoprevention Of Oral And Cervical Cancers
    10. Investigating The Neuroprotective Effects Of Turmeric Extract: Structural Interactions Of Β-Amyloid Peptide With Single Curcuminoids
    11. Nutritional Value, Phytochemical Composition, And Biological Activities Of Edible Curcuma Species: A
    12. Nutritional Value, Phytochemical Composition, And Biological Activities Of Edible Curcuma Species: A Review
    13. Role Of Curcumin In Idiopathic Pulmonary Arterial Hypertension Treatment: A New Therapeutic Possibility
    14. Trans-To-Cis Photoisomerization Of Cyclocurcumin In Different Environments Rationalized By Computational Photochemistry

    dehydrogingerdione
    (ginger extract)

    1. Ginger And Its Constituents: Role In Prevention And Treatment Of Gastrointestinal Cancer
    2. Review On Kukkiladhi Choornam Used In Traditional Medicine And Research Activities
      Zingiber Officinale
    3. Zingiber Officinale Rosc. (Zingiberaceae)

     

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    Demethoxycurcumin
    (Turmeric Root Extract)

    1. A Transcriptomic Analysis Of Turmeric: Curcumin Represses The Expression Of Cholesterol Biosynthetic Genes And Synergizes With Simvastatin
    2. Curcuma Longa Linn. A Phytochemical And Phytopharmacological Review
    3. Extraction Of Curcumin From Turmeric Roots
    4. Role Of Curcumin In Idiopathic Pulmonary Arterial Hypertension Treatment: A New Therapeutic Possibility
    5. Turmeric, The Golden Spice: From Traditional Medicine To Modern Medicine

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    Dianthus caryophyllus seed extract
    (Carnation Extract)

    1. Chemical Contents And Medical Importance Of Dianthus Caryophyllus-A Review
    2. Dianthus Species (Carnation): In Vitro Culture And The Biosynthesis Of Dianthalexin And Other Secondary Metabolites
    3. Expression Of Flavonoid 3′, 5′-Hydroxylase And Acetolactate Synthase Genes In Transgenic Carnation: Assessing The Safety Of A Nonfood Plant
    4. Induction Of Plant virus Resistance: 2. Leaf Extract From Carnation Plants (Dianthus Caryophyllus L.) As Inducer Of Resistance
    5. Potency Of Plant Products In Control Ofvirus Diseases Of Plants

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    Dioscin,Diosgenin,d-Abscisin Ⅱ,Phytic acid,dopamine,cholesterol,ergosterol）

    (Wild Yam Extract （Dioscorea oppositae thunb)

    1. A Boost To The Antiviral Activity: Cholesterol Tagged Peptides Derived From Glycoprotein B Of Herpes Simplex virus Type I
    2. A Cholesterol Tag At The N Terminus Of The Relatively Broad-Spectrum Fusion Inhibitory Peptide Targets An Earlier Stage Of Fusion Glycoprotein Activation And Increases The …
    3. Addition Of A Cholesterol Group To An Hiv-1 Peptide Fusion Inhibitor Dramatically Increases Its Antiviral Potency
    4. Assembled Dopamine Nanolayers Wrapped Carbon Nanotubes As Carbon-Carbon Bi-Functional Nanocatalyst For Highly Efficient Oxygen Reduction Reaction And Antiviral …
    5. Baseline Cholesterol Is Associated With The Response To Antiviral Therapy In Chronic Hepatitis C
    6. Capturing A Fusion Intermediate Of Influenza Hemagglutinin With A Cholesterol-Conjugated Peptide, A New Antiviral Strategy For Influenza virus
    7. Characterization Of Cholesterol Targeting Antimicrobial Peptides And Assessment Of Their Antiviral Activity In Vitro
    8. Cholesterol Conjugation Potentiates The Antiviral Activity Of An Hiv Immunoadhesin
    9. Cholesterol Metabolism–Impact For Sars-Cov-2 Infection Prognosis, Entry, And Antiviral Therapies
    10. Dietary Cholesterol Intake Is Associated With Progression Of Liver Disease In Patients With Chronic Hepatitis C: Analysis Of The Hepatitis C Antiviral Long-Term Treatment …
    11. Dioscin Attenuates High‑Fat Diet‑Induced Insulin Resistance Of Adipose Tissue Through The Irs‑1/Pi3K/Akt Signaling Pathway
    12. Dioscin, A Steroidal Saponin Isolated From Dioscorea Nipponica, Attenuates Collagen-Induced Arthritis By Inhibiting Th17 Cell Response
    13. Dioscin: A Diverse Acting Natural Compound With Therapeutic Potential In Metabolic Diseases, Cancer, Inflammation And Infections
    14. Diosgenin, A Plant-Derived Sapogenin, Exhibits Antiviral Activity In Vitro Against Hepatitis C virus
    15. Diosgenin, A Steroid Saponin Constituent Of Yams And Fenugreek: Emerging Evidence For Applications In Medicine
    16. Dramatic Potentiation Of The Antiviral Activity Of Hiv Antibodies By Cholesterol Conjugation
    17. Effect Of An Antiviral And Vitamins A, C, D On Dopamine And Some Oxidative Stress Markers In Rat Brain Exposed To Ozone
    18. Effects Of Dioscin On Dna Methyltransferase 1 Protein Expression In Human Breast Cancer Cell Lines
    19. Engagement Of Cellular Cholesterol In The Life Cycle Of Classical Swine Fever virus : Its Potential As An Antiviral Target
    20. Ethnopharmacological Potential And Medicinal Uses Of Miracle Herb Dioscorea Spp.
    21. How Are Stat1 And Cholesterol Metabolism Associated In Antiviral Responses?
    22. Il28B Gene Polymorphism Is Correlated With Changes In Low‐Density Lipoprotein Cholesterol Levels After Clearance Of Hepatitis C virus Using Direct‐Acting Antiviral …
    23. Immunometabolic Effect Of Cholesterol In Hepatitis C Infection: Implications In Clinical Management And Antiviral Therapy
    24. Influence Of Basal Level Of The General Cholesterol On Efficacy Of Antiviral Therapy Of The Chronic Hepatitis With Peg-Interferon-Α 2B And Ribavirin
    25. Levels Of Some Antiviral Antibodies In Patients With Different Serum Content Of Total Cholesterol
    26. Lymphocyte Proliferation On Hypersensitivity Of Balb/C Mice After Given Ethanol Extract Tuber Of Dioscorea Alata L.
    27. Medicinal Aspect Of Saponins Shows Their Wide Range Of Pharmacological/Biological Activities
    28. Modulation Of Cell Proteome By 25-Hydroxycholesterol And 27-Hydroxycholesterol: A Link Between Cholesterol Metabolism And Antiviral Defense
    29. Modulation Of Macrophage Antiviral Responses By Lipin-2: Type I Interferon, Inflammasome And Cholesterol Homeostasis
    30. Original Contribution: Top 10 Botanical Ingredients In 2010 Anti‐Aging Creams
    31. P-040. Direct-Acting Antiviral Drugs Used In The Treatment Of Hcv Increase Cholesterol Levels
    32. Polyunsaturated Liposomes Are Antiviral Against Hepatitis B And C virus es And Hiv By Decreasing Cholesterol Levels In Infected Cells
    33. Porcine Reproductive And Respiratory Syndrome virus Nsp1Β And Nsp11 Antagonize The Antiviral Activity Of Cholesterol-25-Hydroxylase Via Lysosomal Degradation
    34. Potency Of Purple Yam (Dioscorea Alata L) As An Immunomodulatory Agent
    35. Skin Ageing: Natural Weapons And Strategies
    36. Synthesis And Biological Evaluation Of Novel 3-O-Tethered Triazoles Of Diosgenin As Potent Antiproliferative Agents
    37. Targeting Cellular Squalene Synthase, An Enzyme Essential For Cholesterol Biosynthesis, Is A Potential Antiviral Strategy Against Hepatitis C virus
    38. The Antiviral Effector Ifitm3 Disrupts Intracellular Cholesterol Homeostasis To Block viral Entry
    39. The Effect Of Antiviral Therapy On Serum Cholesterol Levels In Chronic Hepatitis C
    40. The Effect Of Wild Yam (Dioscorea Villosa) Tincture On Memory And Learning In Mice

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    Douchi extract
    (Semen Sojae Praepatum)

    1. A Retrospective Study On Clinical Features Of And Treatment Methods For 77 Severe Cases Of Sars
    2. Bacillus Strains As Human Probiotics: Characterization, Safety, Microbiome, And Probiotic Carrier
    3. Comparative Evaluation Of Phenolic Profile, Antioxidative And Cytotoxic Activities Of Different Geranium Species
    4. Complementary And Alternative Medicine Is Expected To Make Greater Contribution In Controlling The Prevalence Of Influenza
    5. Effects Of Sodium Nitrite On Proliferation And Apoptosis On Human Hepatocarcinoma Cells
    6. Medical Applications Of Fermentation Technology
    7. Protective Effects Of Xiaoerchiqiaoqingre Granule On Children With Acute Upper Respiratory Tract Infection
    8. The Application Of Fermentation Technology In Traditional Chinese Medicine: A Review
    9. The Optimal Decoction Time Of Yinqiao Powder On Inhibit Influenza A virus Fm1 In Mice

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    Egcg
    (green tea extract)

    1. A Subacute Toxicity Evaluation Of Green Tea (Camellia Sinensis) Extract In Mice
    2. Amino-Functionalized Ordered Mesoporous Silica Sba-15, A Rapid And Efficient Adsorbent For The Adsorption Of (−)-Epigallocatechin Gallate From Green Tea Extract
    3. Anti‐Infective Properties Of Epigallocatechin‐3‐Gallate (Egcg), A Component Of Green Tea
    4. Anti-Invasive Effects Of Green Tea Polyphenol Epigallocatechin-3-Gallate (Egcg), A Natural Inhibitor Of Metallo And Serine Proteases
    5. Antimicrobial Potential Of Epigallocatechin-3-Gallate (Egcg): A Green Tea Polyphenol
    6. Antioxidant And Antiviral Activities Of Lipophilic Epigallocatechin Gallate (Egcg) Derivatives
    7. Antiviral Activity Of Alginate-Oleic Acid Based Coatings Incorporating Green Tea Extract On Strawberries And Raspberries
    8. Antiviral Activity Of Green Tea Catechins Against Feline Calicivirus As A Surrogate For Norovirus
    9. Antiviral Effect Of Catechins In Green Tea On Influenza virus
    10. Antiviral Effect Of Epigallocatechin Gallate (Egcg) On Influenza A virus
    11. Antiviral Effect Of Tea Catechin Egcg On Influenza virus Fm1 Strain In Vitro
    12. Antiviral Mechanism Of Action Of Epigallocatechin-3-O-Gallate And Its Fatty Acid Esters
    13. Comparison Of In Vitro Antiviral Activity Of Tea Polyphenols Against Influenza A And B virus es And Structure–Activity Relationship Analysis
    14. Delineation Of Antimutagenic Activity Of Catechin, Epicatechin And Green Tea Extract
    15. Development Of New Antioxidant Active Packaging Films Based On Ethylene Vinyl Alcohol Copolymer (Evoh) And Green Tea Extract
    16. Epigallocatechin Gallate, A Constituent Of Green Tea, Represses Hepatic Glucose Production
    17. Epigallocatechin Gallate, A Constituent Of Green Tea, Suppresses Cytokine-Induced Pancreatic Β-Cell Damage
    18. Evaluation Of Antiviral Effect Of Epigallocatechin Gallate, Epigallocatechin, Epicatechin Gallate And Green Tea Extract Against Fowl Adenovirus -4
    19. Evaluation Of Green Tea Extract As A Safe Personal Hygiene Against viral Infections
    20. Evaluation Of The Antiviral Activity Of A Green Tea Solution As A Hand-Wash Disinfectant
    21. Fostering The Antiviral Activity Of Green Tea Extract For Sanitizing Purposes Through Controlled Storage Conditions
    22. Green Tea Extract And Its Major Component Epigallocatechin Gallate Inhibits Hepatitis B virus In Vitro
    23. Green Tea Extract And Its Major Polyphenol (−)-Epigallocatechin Gallate Improve Muscle Function In A Mouse Model For Duchenne Muscular Dystrophy
    24. Green Tea Extract For Periodontal Health
    25. Green Tea Polyphenol, Epigallocatechin-3-Gallate, Possesses The Antiviral Activity Necessary To Fight Against The Hepatitis B virus Replication In Vitro
    26. Green Tea: A Promising Natural Product In Oral Health
    27. In Vitro Evaluation Of The Antiviral Activity Of The Synthetic Epigallocatechin Gallate Analog-Epigallocatechin Gallate (Egcg) Palmitate Against Porcine Reproductive And …
    28. Multiple Antiviral Approaches Of (–)-Epigallocatechin-3-Gallate (Egcg) Against Porcine Reproductive And Respiratory Syndrome virus Infection In Vitro
    29. Of Influenza A virus Nuclear Antigen Production And Neuraminidase Activity By A Nutrient Mixture Containing Ascorbic Acid, Green Tea Extract And Amino Acids
    30. virus /sinecatechins-external-genital-warts/?add-to-cart=11221″>Sinecatechins 10% Ointment: A Green Tea Extract For The Treatment Of External Genital Warts
    31. Tea Catechins As A Potential Alternative Anti-Infectious Agent
    32. The Green Tea Catechin, Epigallocatechin Gallate Inhibits Chikungunya virus Infection
    33. The Green Tea Polyphenol, Epigallocatechin-3-Gallate (Egcg)—One Step Forward In Antiviral Therapy Against Hepatitis C virus
    34. The Role Of Green Tea Extract And Powder In Mitigating Metabolic Syndromes With Special Reference To Hyperglycemia And Hypercholesterolemia


    Emodin
    (Rhubarb extract)

    1. A Fruitful Decade From 2005 To 2014 For Anthraquinone Patents
    2. Advances In Bio-Active Constituents, Pharmacology And Clinical Applications Of Rhubarb
    3. Advantages Of Economic Cultivation Of The Genus Rheum Plants In The Republic Of Moldova
    4. Allelopathic Effect Of Rhubarb Extracts On The Growth Of Microcystis Aeruginosa
    5. Aloe-Emodin Is An Interferon-Inducing Agent With Antiviral Activity Against Japanese Encephalitis virus And Enterovirus 71
    6. Aloe-Emodin, Rhein And Emodin Determined By Liquid Chromatography–Mass Spectrometry After Oral Administration Of A Rhubarb Peony Decoction And Rhubarb Extract …
    7. Aloe‐Emodin: A Review Of Its Pharmacology, Toxicity, And Pharmacokinetics
    8. Antiviral Activity Of Aloe-Emodin Against Influenza A virus Via Galectin-3 Up-Regulation
    9. Antiviral Effect Of Emodin From Rheum Palmatum Against Coxsakievirus B_5 And Human Respiratory Syncytial virus In Vitro
    10. Antiviral Effect Of Emodin From Rheum Palmatum Against Coxsakievirus B5 And Human Respiratory Syncytial virus In Vitro
    11. Bidirectional Solid Fermentation Using Trametes Robiniophila Murr. For Enhancing Efficacy And Reducing Toxicity Of Rhubarb (Rheum Palmatum L.)
    12. Chemistry And Pharmacology Of Rhubarb (Rheum Species)— A Review
    13. Emodin Ameliorates Bleomycin-Induced Pulmonary Fibrosis In Rats By Suppressing Epithelial-Mesenchymal Transition And Fibroblast Activation
    14. Experimental Study On The Antiviral Action Of Emodin In Combination With Other Chinese Active Medicine Components On Coxsackie virus B_3 Replication
    15. Interaction Of Five Anthraquinones From Rhubarb With Human Organic Anion Transporter 1 (Slc22A6) And 3 (Slc22A8) And Drug–Drug Interaction In Rats
    16. Pharmacokinetics Of Anthraquinones In Rat Plasma After Oral Administration Of A Rhubarb Extract
    17. Purgative Herbs,”
    18. Simultaneous Determination Of Seven Anthraquinones In Rat Plasma By Ultra High Performance Liquid Chromatography–Tandem Mass Spectrometry And …
    19. Synthesis And Antiviral Activities Of Novel 1, 4-Pentadien-3-One Derivatives Bearing An Emodin Moiety
    20. Synthesis And Antiviral Activity Of Novel Thioether Derivatives Containing 1, 3, 4-Oxadiazole/Thiadiazole And Emodin Moieties
    21. The Experimental Study On Inhibition Effects Of Rhubarb Ethanol Extract On Measles virus Infection In Vitro
    22. The Inhibitory Effect Of Rheum Palmatum Against Coxsackievirus B3In Vitro And In Vivo


    Eriodictyol
    (lemon extract)

    1. A Phytotherapic Formulation For Allergic Rhinitis In Autistic Children
    2. Antibacterial Activity Of Plant Extracts Against Foodborne Pathogenic Bacteria And Food Spoilage Bacteria
    3. Anti-Carcinogenic Effect Of Lemon & Lemon Products In Cancer Therapy: A Summary Of The Evidence
    4. Medical And Nutritional Aspects Of Citrus Bioflavonoids
    5. Use Of Natural Preservatives For Shelf Life Extension Of Fruit Juices


    Eugenitin
    (clove extract)

    1. Clove Extract Inhibits Tumor Growth And Promotes Cell Cycle Arrest And Apoptosis
    2. Green Synthesis And Antibacterial Effects Of Aqueous Colloidal Solutions Of Silver Nanoparticles Using Clove Eugenol
    3. Green Synthesis Of Silver Nanoparticles By Using Eugenol And Evaluation Of Antimicrobial Potential
    4. Hepatoprotective Effect Of Methanolic Extract Of Syzygium Aromaticum Against Hydralazine Induced Toxicity: An In Vitro Study
    5. In Silico Analysis Of Phytochemicals From Clove Against Bronchitis

    ferruginol
    (PodocarpuS ferruginea)

    1. Antibiofilm And Antiviral Potential Of Leaf Extracts From Moringa Oleifera And Rosemary (Rosmarinus Officinalis Lam.)
    2. Anti-Herpetic And Anti-Dengue Activity Of Abietane Ferruginol Analogues Synthesized From (+)-Dehydroabietylamine
    3. Antiviral Activity Of Phytochemicals: A Comprehensive Review
    4. Antiviral Effect Of Compounds Derived From Angelica Archangelica L. On Herpes Simplex virus -1 And Coxsackievirus B3 Infections
    5. Cucurbitacin B Interacts Synergistically With Antibiotics Against Staphylococcus Aureus Clinical Isolates And Exhibits Antiviral Activity Against Hsv-1
    6. Cytotoxic, Immunomodulatory, Antimycotic, And Antiviral Activities Of Semisynthetic 14-Hydroxyabietane Derivatives And Triptoquinone C-4 Epimers
    7. Diterpenes And Their Derivatives As Promising Agents Against Dengue virus And Dengue Vectors: A Literature‐Based Review
    8. Epicubenol And Ferruginol Induce Dc From Human Monocytes And Differentiate Il-10-Producing Regulatory T Cells In Vitro
    9. Foliage Oil Terpenes Of Prumnopitys Ferruginea (D. Don) Laubenf. Variation In Acorenone Levels
    10. Specific Plant Terpenoids And Lignoids Possess Potent Antiviral Activities Against Severe Acute Respiratory Syndrome Coronavirus
    11. Synthesis, Antiviral And Cytotoxic Activity Of Novel Terpenyl Hybrid Molecules Prepared By Click Chemistry

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    Fisetin
    (Rhus succedanea L)

    1. Antifungal And Cytotoxicity Activities Of The Fresh Xylem Sap Of Hymenaea Courbaril L. And Its Major Constituent Fisetin
    2. Anti-Septic Effects Of Fisetin In Vitro And In Vivo
    3. Antiviral Activity Of Some Flavonoids On Herpes Simplex virus es
    4. Emerging Novel Drug Delivery Strategies For Bioactive Flavonol Fisetin In Biomedicine
    5. Ethnomedicines For The Development Of Anti-Herpesvirus Agent
    6. Fisetin As A Promising Antifungal Agent Against Cryptocococcus Neoformans Species Complex
    7. Fisetin Yeast-Based Bio-Capsules Via Osmoporation: Effects Of Process Variables On The Encapsulation Efficiency And Internalized Fisetin Content
    8. Flavone: An Important Scaffold For Medicinal Chemistry
    9. Flavonol-Rich Rvhxr From Rhus Verniciflua Stokes And Its Major Compound Fisetin Inhibits Inflammation-Related Cytokines And Angiogenic Factor In Rheumatoid Arthritic …
    10. In Vitro Antifungal Activity And Cytotoxicity Effects Of Fresh Xylem Sap Of Hymenaea Courbaril L. And Its Major Constituent Fisetin
    11. In Vitro Antiviral Activity Of Fisetin, Rutin And Naringenin Against Dengue virus Type-2
    12. Interference Of Fisetin With Targets Of The Nuclear Factor-Κb Signal Transduction Pathway Activated By Epstein-Barr virus Encoded Latent Membrane Protein 1.
    13. Study Of The Interaction Between Fisetin And Human Serum Albumin: A Biophysical Approach

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    Flavonol glucoside
    (Trichilia connaroides leaves extract)

    1. A Survey Of Plants With Anti-Hiv Active Compounds And Their Modes Of Action
    2. Absorption And Metabolism Of [2-14C] Quercetin-4′-Glucoside In Rats Ex Vivo And In Vitro
    3. Antioxidant And Cytotoxic Flavonoids From The Flowers Of Melastoma Malabathricum L.
    4. Extreme Effects Of Seabuckthorn Extracts On Influenza virus es And Human Cancer Cells And Correlation Between Flavonol Glycosides And Biological Activities Of …
    5. Flavonol Catabolism In Arabidopsis Thaliana: Subcellular Localization Of A Flavonol 3-O-Glucoside Beta-Glucosidase And Biochemical Evidence For A Flavonol …
    6. In Vitro Antiviral Activity Of Twenty-Seven Medicinal Plant Extracts From Southwest Nigeria Against Three Serotypes Of Echovirus es
    7. Lipase-Catalyzed Direct And Regioselective Acylation Of Flavonoid Glucoside For Mechanistic Investigation Of Stable Plant Pigments
    8. Localization Of Partially Methylated Flavonol Glucosides In Chrysosplenium Americanum: Immunogold Labeling
    9. The Flavonoid Isoquercitrin Precludes Initiation Of Zika virus Infection In Human Cells

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    forskolin
    (Coleus Forskohlii Extract)

    1. A Novel Method To Augment Extraction Of Mangiferin By Application Of Microwave On Three Phase Partitioning
    2. A Place Of Natural Safety
    3. Anticonvulsant Activity Of Extracts Of Plectranthus Barbatus Leaves In Mice
    4. Anti-Hiv Activity Of Indian Medicinal Plants
    5. Anti-Hiv Potential Of Medicinally Important Plants Rajandeep Kaur And Rajeev Kharb
    6. Arbuscular Mycorrhizal Symbiosis And Active Ingredients Of Medicinal Plants: Current Research Status And Prospectives
    7. B Radiation In Altering The Metabolite Profile, Essential Oil Content And Composition, And Free Radical Scavenging Activities Of Coleus Forskohlii, An Indigenous …
    8. Bk virus Early Rna Transcripts In Stably Transformed Cells: Enhanced Levels Induced By Dibutyryl Cyclic Amp, Forskolin And 12-O-Tetradecanoylphorbol-13-Acetate …
    9. Cent Percent Safe Centum Plants For Antiobesity
    10. Cloning And Expression Analysis Of Chalcone Synthase Gene From Coleus Forskohlii
    11. Coleus Spp.: In Vitro Culture And The Production Of Forskolin And Rosmarinic Acid
    12. Complementary And Alternative Medicine In Asthma And Copd
    13. Cough Control The Natural Way
    14. C-Terminal Trans-Activation Sub-Region Of Vp16 Is Uniquely Required For Forskolin-Induced Herpes Simplex virus Type 1 Reactivation From Quiescently Infected …
    15. Distinct Effect Of Forskolin And Interferon-Γ On Cell Proliferation And Regulation Of Histocompatibility Antigen Expression In Hematopoietic Cells
    16. Enhanced Accumulation Of Scopoletin In Cell Suspension Culture Of Spilanthes Acmella Murr. Using Precursor Feeding
    17. Forskolin Ameliorates Scopolamine Induced Memory Impairment In Rats
    18. Forskolin Increases Propagation Of Influenza virus In Madin-Darby Canine Kidney Cells (Vac5P. 1118)
    19. Herpesvirus Quiescence In Neuronal Cells. V: Forskolin-Responsiveness Of The Herpes Simplex virus Type 1 Α0 Promoter And Contribution Of The Putative Camp Response …
    20. Immune-Regulatory Transcriptional Responses In Multiple Organs Of Atlantic Salmon After Tributyltin Exposure, Alone Or In Combination With Forskolin
    21. In Vitro Inhibition Of Esbl Positive Multidrug Resisting Uropathogenic Bacteria Using Coleus Forskohlii
    22. Increased Cyclic Amp Response To Forskolin In Epstein-Barr virus -Transformed Human B-Lymphocytes Derived From Schizophrenics
    23. Inhibition Of Tumor Cell Proliferation By Coleon C
    24. Inhibitory Effect Of Some Triterpenoid Saponins On Glucose Transport In Tumor Cells And Its Application To In Vitro Cytotoxic And Antiviral Activities
    25. Isolation, Identification And Bioactive Potential Of Bacterial Endophytes From Coleus
    26. Microwave-Assisted Extraction Of Forskolin From Coleus Roots And Its Purification By Adsorptive Separation Using Functionalized Polymer Designed By Molecular …
    27. Phytochemical And Molecular Analyses Of Some Coleus Cultivars Cultivated In Egypt
    28. Plant-Derived Natural Products In Drug Discovery And Development: An Overview
    29. Positive Inotropic Effect Of The Leaf Extracts Of Parent And Tissue Culture Plants Of Coleus Amboinicus On An Isolated Perfused Frog Heart Preparation
    30. Rosmarinic Acid Production By Coleus Forskohliihairy Root Cultures
    31. Studies On Phytochemical Analysis, Antioxidant And Lipid Peroxidation Inhibitory Effects Of A Medicinal Plant, Coleus Forskohlii
    32. Supplementary Figure S1. Neuronal Conversion In Response To Different Dosage Of Forskolin (Fsk). Tuj1+ Cells Were Examined 5 Days Post Treatment Of Imr-90 …
    33. V Coleus Spp.: In Vitro Culture And The Production


    Fructus Perillae extract
    (Perillafrutescens extract)

    1. Chinese Medicinal Herbs For Childhood Pneumonia: A Systematic Review Of Effectiveness And Safety
    2. Ethnomedicinal, Phytochemical And Pharmacological Investigations Of Perilla Frutescens (L.) Britt.
    3. Improved Pulmonary Inflammation And Fibrosis Progression After Influenza A (H1N1) Infection By Chinese Herbal Medicine: A Case Report
    4. Utilization Of Chinese Medicine For Respiratory Discomforts By Patients With A Medical History Of Tuberculosis In Taiwan


    fumarophycine
    (Laptopyrum Reichb)

    1. A Perspective On The Anti-Infective Activity Of Goldenseal (Hydrastis Canadensis) And Its Contribution To The Development Of Multidrug Pump Inhibitors
    2. Anti-Hepatitis B Activity Of Isoquinoline Alkaloids Of Plant Origin
    3. Antiviral And Antimicrobial Evaluation Of Some Heterocyclic Compounds From Turkish Plants
    4. Antiviral And Antimicrobial Profiles Of Selected Isoquinoline Alkaloids From Fumaria And Corydalis Species
    5. Cytotoxicity, Antiviral And Antimicrobial Activities Of Alkaloids, Flavonoids, And Phenolic AcidsDegree Of Patient Satisfaction With Health Care Performance Assesed By Marketing
    6. SurveysEvaluation Of Antimicrobial Activity Of Some Medicinal Plant Extracts Grown On Gaza Strip (Palestine) Against Some Bacterial PathogensLead Compounds And Drug Candidates
    7. From Some Turkish Plants For Human HealthNatural Antiviral Compounds


    galangin
    (Alpinia officinarum Hance root extract)

    1. Analysis Of Potential Amino Acid Biomarkers In Brain Tissue And The Effect Of Galangin On Cerebral Ischemia
    2. Antifungal Activity Of Alpinia Officinarum Hance Against Candida Albicans
    3. Anti-Obesity Effects Of Galangin, A Pancreatic Lipase Inhibitor In Cafeteria Diet Fed Female Rats
    4. Antiviral Activity Of Galangin Isolated From The Aerial Parts Of Helichrysum Aureonitens
    5. Chemopreventive Mechanisms Of Galangin Against Hepatocellular Carcinoma: A Review
    6. Chromatographic Fingerprint Analysis And Quantitative Evaluate The Rhizomes Of Alpinia Officinarum Hance (Lesser Galangal)
    7. Comparative Pharmacokinetic Study Of Five Flavonoids In Normal Rats And Rats With Gastric Ulcer Following Oral Administration Of Mongolian Medicine, Shudage-4 By …
    8. Comparison Of Antioxidant Activity And Main Active Compounds Among Different Parts Of Alpinia Officinarum Hance Using High-Performance Thin Layer …
    9. Discrimination Of Two Cultivars Of Alpinia Officinarum Hance Using An Electronic Nose And Gas Chromatography-Mass Spectrometry Coupled With Chemometrics
    10. Galangin As A Plant Phenolic And Usage In Health And Disease
    11. Galangin Suppresses Renal Inflammation Via The Inhibition Of Nf-Κb, Pi3K/Akt And Nlrp3 In Uric Acid Treated Nrk-52E Tubular Epithelial Cells
    12. Galangin, A Dietary Flavonoid, Ameliorates Hyperglycaemia And Lipid Abnormalities In Rats With Streptozotocin-Induced Hyperglycaemia
    13. Galangin, A Dietary Flavonoid, Improves Antioxidant Status And Reduces Hyperglycemia-Mediated Oxidative Stress In Streptozotocin-Induced Diabetic Rats
    14. Galangin, A Natural Flavonoid Reduces Mitochondrial Oxidative Damage In Streptozotocin-Induced Diabetic Rats
    15. Growth Of A Human Mammary Tumor Cell Line Is Blocked By Galangin, A Naturally Occurring Bioflavonoid, And Is Accompanied By Down-Regulation Of Cyclins D3 …
    16. Protective Effect Of Galangin In Concanavalin A-Induced Hepatitis In Mice
    17. Qualitative Analysis Of Various Plant Extracts Of Alpinia Officinarum.
    18. Simultaneous Quantification Of Seventeen Bioactive Components In Rhizome And Aerial Parts Of Alpinia Officinarum Hance Using Lc-Ms/Ms
    19. Study On Extraction Technology Of Total Flavonoids From Alpinia Officinarum Hance
    20. Synergistic Effects Of The Combination Of Galangin With Gentamicin Against Methicillin-Resistant Staphylococcus Aureus

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    gallic acid
    (Rheumpalmatum L.root)

    1. Antioxidant Activity And Total Phenolic Content Of Rheum Palmatum Roots
    2. Antioxidant Phenolic Constituents In Roots Of Rheum Officinale And Rubia Cordifolia:  Structure−Radical Scavenging Activity Relationships
    3. Anti-Pandemic Influenza A (H1N1) virus Potential Of Catechin And Gallic Acid
    4. Antiviral Activity Of Gallic Acid Against Coxsackievirus B3 And Coxsackievirus B4
    5. Antiviral Effects Of Black Raspberry (Rubus Coreanus) Seed And Its Gallic Acid Against Influenza virus Infection
    6. Antiviral Effects Of Black Raspberry (Rubus Coreanus) Seed Extract And Its Polyphenolic Compounds On Norovirus Surrogates
    7. Application Of High‐Speed Counter‐Current Chromatography For The Isolation Of Antiviral Eremophilenolides From Ligularia Atroviolacea
    8. Bidirectional Solid Fermentation Using Trametes Robiniophila Murr. For Enhancing Efficacy And Reducing Toxicity Of Rhubarb (Rheum Palmatum L.)
    9. Ethnopharmacologic Study Of Chinese Rhubarb
    10. Frangulosid As A Novel Hepatitis B virus Dna Polymerase Inhibitor: A Virtual Screening Study
    11. Gallic Acid Decreases Hepatitis C virus Expression Through Its Antioxidant Capacity
    12. In Silico Study Of Gallic Acid Derivatives As Novel Antiviral Agents Of Hepatitis C
    13. In Vitro Antioxidant Activity Of Sanguisorbae Radix Ethanol Extracts
    14. Ionic Liquid-Immobilized Nay Zeolite-Based Matrix Solid Phase Dispersion For The Extraction Of Active Constituents In Rheum Palmatum L.
    15. Limonium Sinense And Gallic Acid Suppress Hepatitis C virus Infection By Blocking Early viral Entry
    16. Limonium Sinense And Gallic Acid Suppress Hepatitis C virus Infection By Blocking Early viral Entry.
    17. Radix Et Rhizoma Rhei — Dahuang
    18. Reduction In Antiviral Activity Of Human Beta Interferon By Gallic Acid.
    19. Rumex Dentatus, Commelina Benghalensis, Ajuga Bracteosa, Ziziphus Mauritiana As Well As Their Compounds Of Gallic Acid And Emodin Against Dengue virus
    20. Screening And Analyzing The Potential Bioactive Components From Rhubarb, Using A Multivariate Data Processing Approach And Ultra-High Performance Liquid …
    21. Screening Of Traditional Medicines For Their Inhibitory Activity Against Hiv‐1 Protease
    22. Significant Elevation Of Antiviral Activity Of Strictinin From Pu’Er Tea After Thermal Degradation To Ellagic Acid And Gallic Acid
    23. Two New Compounds From The Roots Of Rheum Palmatum

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    Genistein

    (Genista tinctoria Linn root)

    1. Anticarcinogenic Effects Of Isoflavones May Be Mediated By Genistein In Mouse Mammary Tumor virus -Induced Breast Cancer
    2. Genistein As Antiviral Drug Against Hiv Ion Channel
    3. Genistein Has Antiviral Activity Against Herpes B virus And Acts Synergistically With Antiviral Treatments To Reduce Effective Dose
    4. Genistein Inhibits African Swine Fever virus Replication In Vitro By Disrupting viral Dna Synthesis
    5. Genistein Inhibits The Replication Of Avian Leucosis virus Subgroup J In Df-1 Cells
    6. Genistein, A General Kinase Inhibitor, As A Potential Antiviral For Arenaviral Hemorrhagic Fever As Described In The Pirital virus -Syrian Golden Hamster Model
    7. Genistein, A Protein Tyrosine Kinase Inhibitor, Suppresses The Fusogenicity Of Moloney Murine Leukemia virus Envelope Protein In Xc Cells
    8. Human Immunodeficiency virus Type 1 Induction Mediated By Genistein Is Linked To Cell Cycle Arrest In G2
    9. Inhibition Of Herpes Simplex virus Replication By Genistein, An Inhibitor Of Protein-Tyrosine Kinase
    10. Inhibition Of Lassa virus And Ebola virus Infection In Host Cells Treated With The Kinase Inhibitors Genistein And Tyrphostin
    11. Inhibitory Effects Of Flavonoids On P-Glycoprotein In Vitro And In Vivo: Food/Herb-Drug Interactions And Structure–Activity Relationships
    12. Inhibitory Effects Of Genistein On Abnormal Changes Of Proliferation And Apoptosis Caused By Herpes Simplex virus -1 Infectiom In Human Glioma Cell
    13. The Reduction Of Nfkappab By Genistein In T Lymphoma Cell Lines Generated By Mink Cell Focus-Forming virus .

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    Glycyrrhizic acid
    (licorice root extract)

    1. Allicin And Glycyrrhizic Acid Display Antiviral Activity Against Latent And Lytic Kaposi Sarcoma-Associated Herpesvirus
    2. Antiviral Activity Of Glycyrrhizic Acid Derivatives Against Sars− Coronavirus
    3. Antiviral Carbon Dots: Glycyrrhizic‐Acid‐Based Carbon Dots With High Antiviral Activity By Multisite Inhibition Mechanisms (Small 13/2020)
    4. Antiviral Properties Of Glycyrrhizic Acid And Its Semisynthetic Derivatives.
    5. Effect Of A Combination Of Glutamyl-Tryptophan And Glycyrrhizic Acid On The Course Of Acute Infection Caused By Influenza (H3H2) virus In Mice
    6. Effects Of Glycyrrhiza Polysaccharide And Glycyrrhizic Acid On Cellular Infectivity Of Newcastle Disease virus To Chick Embryo Fibroblast
    7. Effects Of Glycyrrhizic Acid (Viusid-Vet® Powder) On The Reduction Of Influenza virus Spread And On Production Parameters In Pigs
    8. Glycyrrhizic Acid As The Antiviral Component Of Glycyrrhiza Uralensis Fisch. Against Coxsackievirus A16 And Enterovirus 71 Of Hand Foot And Mouth Disease
    9. Glycyrrhizic Acid Derivatives As Dengue virus Inhibitors
    10. Glycyrrhizic Acid Derivatives As Influenza A/H1N1 virus Inhibitors
    11. Glycyrrhizic Acid Inhibits Influenza virus Growth In Embryonated Eggs.
    12. Glycyrrhizic Acid Inhibits virus Growth And Inactivates virus Particles
    13. Glycyrrhizic Acid-Alpha-Glutamyltryptophan Against The Experimental Lethal Influenza Infection In White Mice Caused By The Oseltamivir-Resistant Strain Of The virus
    14. Glycyrrhizic‐Acid‐Based Carbon Dots With High Antiviral Activity By Multisite Inhibition Mechanisms
    15. In Vitro Antiviral Activity Of Indigenous Glycyrrhizin, Licorice And Glycyrrhizic Acid (Sigma) On Japanese Encephalitis virus .
    16. Inhibitory Effects Of Some Derivatives Of Glycyrrhizic Acid Against Epstein-Barr virus Infection: Structure–Activity Relationships
    17. Mechanism Of Action Of Glycyrrhizic Acid In Inhibition Of Epstein-Barr virus Replication In Vitro
    18. Prospects For The Creation Of New Antiviral Drugs Based On Glycyrrhizic Acid And Its Derivatives (A Review)
    19. Research Progress Of Glycyrrhizic Acid On Antiviral Activity
    20. Synthesis And Antiviral Activity Of 18Α-Glycyrrhizic Acid And Its Esters
    21. Synthesis And Antiviral Activity Of Glycyrrhizic-Acid Conjugates With Aromatic Amino Acids
    22. Synthesis And Antiviral Activity Of Novel Glycyrrhizic Acid Conjugates With D-Amino Acid Esters
    23. The Complex Glycyrrhizic Acid-Alpha-Glutamyl-Tryptophan Against Experimental Lethal Influenza Infection In White Mice Caused By Oseltamivir-Resistant Strain Of The virus
    24. The Synthesis And Antiviral Activity Of Glycyrrhizic Acid Conjugates With Α-D-Glucosamine And Some Glycosylamines
    25. Using Glycyrrhizic Acid To Target Sumoylation Processes During Epstein-Barr virus Latency

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    gossypol
    (cotton seed extract)

    1. Amino Acid Derivatives Of The (−) Enantiomer Of Gossypol Are Effective Fusion Inhibitors Of Human Immunodeficiency virus Type 1
    2. Antiviral Activities Of Gossypol And Its Derivatives Against Herpes Simplex virus Type Ii
    3. Antiviral Activity Of Gossypol And Apogossypol
    4. Antiviral Mechanism Study Of Gossypol And Its Schiff Base Derivatives Based On Reactive Oxygen Species (Ros)
    5. Gss (Gossypol-Beta-Aminoethylsodium Sulfate), In Combination With A Specific Vaccine In Experimental Infection With The Human Acute Encephalomyelitis virus
    6. Inactivation Of Human Immunodeficiency virus In Vitro By Gossypol
    7. Inhibiting Herpes Simplex virus Type 2 Infection In Human Epithelial Cells By Gossypol, A Potent Spermicidal And Contraceptive Agent.
    8. Inhibition Of Human Immunodeficiency virus Type I Replication By Derivatives Of Gossypol
    9. Lecithin Organogels With A Carcinolytic Drug K-2, Antiviral Drugs Of Megosin, Ragosin And Gossypol For Transdermal Delivery
    10. Polymer Complexes Of Gossypol And Their Antiviral Activity
    11. Proteomic And virus -Induced Gene Silencing (Vigs) Analyses Reveal That Gossypol, Brassinosteroids, And Jasmonic Acid Contribute To The Resistance Of Cotton To …
    12. Selective Inhibition Of Human Immunodeficiency virus Type 1 Replication By The (-) But Not The (+) Enantiomer Of Gossypol.
    13. Synthesis And Antiviral Activities Of Amino Acid Derivatives Of Gossypol
    14. Synthesis And Antiviral Activities Of Novel Gossypol Derivatives
    15. Synthesis And Antiviral Activity Of Gossypol Derivatives
    16. Synthesis And Antiviral, Insecticidal, And Fungicidal Activities Of Gossypol Derivatives Containing Alkylimine, Oxime Or Hydrazine Moiety

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    Guineensine
    (Piper longum L.)

    1. A Review On Study Of Medicinal Uses Of Some Aromatic Plants
    2. Hplc Assisted Chemobiological Standardization Of Α-Glucosidase-I Enzyme Inhibitory Constituents From Piper Longum Linn-An Indian Medicinal Plant
    3. Overview Of Chemical Constituents And Pharmacological Activities Of Piper Longum Linn.
    4. Prevention And Treatment Of Different Health Problems By Common Peoples Diet (Haleem)
    5. Review On Kukkiladhi Choornam Used In Traditional Medicine And Research Activities

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    GYPSUM FIBROSUM
    extract
    (Gypsum extract)

    1. Antiviral Herbs-Present And Future
    2. Effects Of Chinese Herbal Formula Maxing Shigan Powder On Iga Secreting Cells In Chicken Bronchus
    3. Mechanism By Which Ma-Xing-Shi-Gan-Tang Inhibits The Entry Of Influenza virus
    4. On The Clinical Application Of Decoction Of Herba Ephedrae, Semen Armeniacae Amarum, Radix Glycyrrhizae And Gypsum Fibrosum Based On An Understanding Of” …
    5. Study On The Rationality For Antiviral Activity Of Flos Lonicerae Japonicae-Fructus Forsythiae Herb Couple Preparations Improved By Chito-Oligosaccharide Via Integral …

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    Hawthorn Extract flavone
    (Crataegus pinnatifida Bunge)

    1. Anti-Inflammatory Potential Of Flavonoid Contents From Dried Fruit Of Crataegus Pinnatifida In Vitro And In Vivo
    2. Corosolic Acid Isolated From The Fruit Of Crataegus Pinnatifida Var. Psilosa Is A Protein Kinase C Inhibitor As Well As A Cytotoxic Agent
    3. Crataegus Pinnatifida: Chemical Constituents, Pharmacology, And Potential Applications
    4. Determination Of Activity Of Polysaccharide Extracted From Crataegus Pinnatifida Leaves [J]
    5. Effects Of Hawthorn Seed And Pulp Extracts On The Central Nervous System
    6. Hawthorn: Crataegus Oxyacantha, Crataegus Monogyna And Related Species
    7. Hplc Quantification Of Vitexine-2″-O-Rhamnoside And Hyperoside In Three Crataegus Species And Their Antimicrobial And Antiviral Activities
    8. Hypolipidemic Components From Medicine Food Homology Species Used In China: Pharmacological And Health Effects
    9. Interactions Between Nutraceuticals/Nutrients And Therapeutic Drugs
    10. Major Triterpenoids In Chinese Hawthorn “Crataegus Pinnatifida” And Their Effects On Cell Proliferation And Apoptosis Induction In Mda-Mb-231 Cancer Cells
    11. Optimization Of High-Speed Counter-Current Chromatography For Separation Of Polyphenols From The Extract Of Hawthorn (Crataegus Laevigata) With Response Surface …
    12. Protective Effect Of Hawthorn Extract Against Genotoxicity Induced By Cyclophosphamide In Mouse Bone Marrow Cells
    13. Radioprotective Effects Of Hawthorn Fruit Extract Against Gamma Irradiation In Mouse Bone Marrow Cells
    14. Synthetic Study On Secoderivatives Of 6-Azauridine As Potential Antiviral Agents
    15. Toxicity Of Crataegus (Hawthorn) Extract (Ws 1442)

    Herba Dendrobii extract

    (Dendrobium nobile Lindl)

    1. A Polysaccharide Found In Dendrobium Nobile Lindl Stimulates Calcium Signaling Pathway And Enhances Tobacco Defense Against Tmv
      A Review And Comment On The Current Situation Of 2019 Novel Coronavirus Prevention By Traditional Chinese Medicine
    2. Anti-Aging Properties Of Dendrobium Nobile Lindl.: From Molecular Mechanisms To Potential Treatments
    3. Genetic Stability And Phytochemical Analysis Of The In Vitro Regenerated Plants Of Dendrobium Nobile Lindl., An Endangered Medicinal Orchid
    4. Naturally Potential Antiviral Agent Polysaccharide From Dendrobium Nobile Lindl
    5. The Natural Product Berberine Is A Human Prolyl Oligopeptidase Inhibitor
    6. The Structure-Activity Relationship And Molecular Mechanism Of Anti-Tumor Polysaccharide Isolated From Dendrobium Nobile Lindl.


    herbacetin
    (flaxseed)

    1. 12 Flaxseed Constituents And Human Health
    2. Antioxidant, Antimicrobial And Anti-Hcv Activities Of Lignan Extracted From Flaxseed
    3. Bioactive Phytochemicals In Flaxseed
    4. Chemical Studies On The Constituents Of Linum Spp
    5. Covid-19 And Flavonoids: In Silico Molecular Dynamics Docking To The Active Catalytic Site Of Sars-Cov And Sars-Cov-2 Main Protease
    6. Facile Synthesis Of Norwogonin, Isoscutellarein, And Herbacetin
    7. Herbal Products In Hypertension: Paradox Or, Paragon
    8. I Vitro A Tioxida T Activity Of Etha Olic Extract Of Li Um Usitatissimum
      Meta-Analysis Of Flavonoids With Antiviral Potential Against Coronavirus
    9. Physicochemical, Sensorial And Microbiological Properties Of Mishti Dahi Supplemented With Flax Lignan During Storage And Its Antidiabetic Activity
    10. Pleiotropic Effects Of Bioactive Phytochemicals (Polyphenols And Terpenes)
    11. Potential Of Plant Bioactive Compounds As Sars-Cov-2 Main Protease (Mpro) And Spike (S) Glycoprotein Inhibitors: A Molecular Docking Study
      Separation Of Four Flavonoids From Rhodiola Rosea By On-Line Combination Of Sample Preparation And Counter-Current Chromatography
    12. Urinary Lignan And Isoflavonoid Excretion In Premenopausal Women Consuming Flaxseed Powder

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    Hesperetin
    (Citrus Aurantium Extract)

    1. Chiral Separation Of Hesperetin And Hesperetin-O-Glycoside In Capillary Electrophoresis Using Microbial Β-1, 2-Glucans
    2. Citrus Flavonoids As Functional Ingredients And Their Role In Traditional Chinese Medicine
    3. Comparative Effects Of Peel Extract From Nigerian Grown Citrus On Body Weight, Liver Weight And Serum Lipids In Rats Fed A High-Fat Diet
    4. Determination Of Polymethoxylated Flavones In Peels Of Selected Jamaican And Mexican Citrus (Citrus Spp.) Cultivars By High‐Performance Liquid Chromatography
    5. Effect Of Naringenin, Hesperetin And Their Glycosides Forms On The Replication Of The 17D Strain Of Yellow Fever virus
    6. Evolution Of Polymethoxy Flavones During Development Of Tangelo Nova Fruits
    7. Flavonoids Of Korean Citrus Aurantium L. Induce Apoptosis Via Intrinsic Pathway In Human Hepatoblastoma Hepg2 Cells
    8. Flavonoids: Promising Natural Compounds Against viral Infections
    9. Gary Williamson Nestlé Research Center Lausanne, Switzerland Yongping Bao Institute Of Food Research
    10. Hesperetin Protects Crayfish Procambarus Clarkii Against White Spot Syndrome virus Infection
    11. Identification Of Flavanones From Peel Of Citrus Changshan-Huyou Yb Chang, By Hplc–Ms And Nmr
    12. In Silico Study On Anti-Chikungunya virus Activity Of Hesperetin
    13. Induction Of The Cell Cycle Arrest And Apoptosis By Flavonoids Isolated From Korean Citrus Aurantium L. In Non-Small-Cell Lung Cancer Cells
    14. Inhibition Of Chikungunya virus Replication By Hesperetin And Naringenin
    15. Nobiletin: Efficient And Large Quantity Isolation From Orange Peel Extract

    ” alt=”” width=”500″ height=”334″ data-src=”https://theinterstellarplan.com/wp-content/uploads/2020/07/Hesperidin.jpg” data-srcset=”https://theinterstellarplan.com/wp-content/uploads/2020/07/Hesperidin.jpg 500w, https://theinterstellarplan.com/wp-content/uploads/2020/07/Hesperidin-300×200.jpg 300w, https://theinterstellarplan.com/wp-content/uploads/2020/07/Hesperidin-219×146.jpg 219w, https://theinterstellarplan.com/wp-content/uploads/2020/07/Hesperidin-50×33.jpg 50w, https://theinterstellarplan.com/wp-content/uploads/2020/07/Hesperidin-112×75.jpg 112w” data-sizes=”(max-width: 500px) 100vw, 500px” />
    hesperidin
    (Pericarpium Citri Reticulatae Extract)

    Is hesperidin essential for prophylaxis and treatment of COVID-19 Infection?

    SARS-CoV-2 or COVID-19 is representing the major global burden that implicated more than 4.7 million infected cases and 310 thousand deaths worldwide in less than 6 months. The prevalence of this pandemic disease is expected to rise every day. The challenge is to control its rapid spread meanwhile looking for a specific treatment to improve patient outcomes. Hesperidin is a classical herbal medicine used worldwide for a long time with an excellent safety profile. Hesperidin is a well-known herbal medication used as an antioxidant and anti-inflammatory agent. Available shreds of evidence support the promising use of hesperidin in prophylaxis and treatment of COVID 19. Herein, we discuss the possible prophylactic and treatment mechanisms of hesperidin based on previous and recent findings. Hesperidin can block coronavirus from entering host cells through ACE2 receptors which can prevent the infection. Anti-viral activity of hesperidin might constitute a treatment option for COVID-19 through improving host cellular immunity against infection and its good anti-inflammatory activity may help in controlling cytokine storm. Hesperidin mixture with diosmin co-administrated with heparin protect against venous thromboembolism which may prevent disease progression. Based on that, hesperidin might be used as a meaningful prophylactic agent and a promising adjuvant treatment option against SARS-CoV-2 infection.

    Hesperidin and SARS-CoV-2: New Light on the Healthy Functions of Citrus Fruit

    Among the many approaches to COVID-19 prevention, the possible role of diet has so far been somewhat marginal. Nutrition is very rich in substances with a potential beneficial effect on health and some of these could have an antiviral action or in any case be important in modulating the immune system and in defending cells from the oxidative stress associated with infection. This short review draws the attention on some components of Citrus fruits and especially of the orange (Citrus sinensis), well known for its vitamin content, but less for the function of its flavonoids. Among the latter, hesperidin has recently attracted the attention of researchers, because it binds to the key proteins of the SARS-CoV-2 virus. Several computational methods, independently applied by different researchers, showed that hesperidin has a low binding energy both with the coronavirus “spike” protein, and with the main protease that transforms the early proteins of the virus (pp1a and ppa1b) into the complex responsible for viral replication. The affinity of hesperidin for these proteins is comparable if not superior to that of common chemical antivirals. The preventive efficacy of vitamin C, at dosage attainable by diet, against viral infections is controversial, but recent reviews suggest that this substance may be useful in case of increased stress on the immune system. Finally, the reasons that suggest undertaking appropriate research on the Citrus fruits addition in the diet, as a complementary prevention and treatment of COVID-19, are discussed.
    1. Anti-Asthmatic Activity Of Alkaloid Compounds From Pericarpium Citri Reticulatae (Citrus Reticulata ‘Chachi’)
    2. Anti-Lipid Peroxidation And Oxygen Free Radical Scavenging Activity Of Pericarpium Citri Reticulatae Extract
    3. Anti-Lipid Peroxidation And Oxygen Free Radical Scavenging Activity Of Pericarpium Citri Reticulatae Extract [J]
    4. Effects Of Aging On The Phytochemical Profile And Antioxidative Activity Of Pericarpium Citri Reticulatae ‘Chachiensis’
    5. Evaluation Of Anti-Lipase Activity And Bioactive Flavonoids In The Citri Reticulatae Pericarpium From Different Harvest Time
    6. Evaluation Of Bioactive Flavonoids And Antioxidant Activity In Pericarpium Citri Reticulatae (Citrus Reticulata ‘Chachi’) During Storage
    7. Experimental Study On The Effect Of The Combined Use Of Radix Ginseng And Pericarpium Citri Reticulatae On The Function Of Anti-Fatigue In Mice
    8. Identification Of Anti-Asthmatic Compounds In Pericarpium Citri Reticulatae And Evaluation Of Their Synergistic Effects
    9. Protective Effect Of Flavonoids From Pericarpium Citri Reticulatae (Chenpi) Against Oxidative Stress Induced By Exhaustive Exercise

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    himachalol
    (Cupressus funebris Endl.)

    1. Antibacterial Activity Of Magnolol And Honokiol In Combination With Antibiotics.
    2. Design, Synthesis And Antibacterial Evaluation Of Honokiol Derivatives
    3. Flavonoid–Induced Nephropathy; Increasing Awareness
    4. Hplc Quantification Of Flavonoids And Biflavonoids Incupressaceae Leaves
    5. In Vitro Antibacterial And Anti-Inflammatory Effects Of Honokiol And Magnolol Against Propionibacterium Sp.
    6. In Vitro Synergism Of Magnolol And Honokiol In Combination With Antibacterial Agents Against Clinical Isolates Of Methicillin-Resistant Staphylococcus Aureus …
    7. Studies On Dental Caries Prevention By Traditional Chinese Medicine-5-A Comparison Of Antibacterial Action Of Magnolol, Honokiol And Related Compounds Against …
    8. The In Vitro Anticancer Effects Of Himachalol From Cedrus Libani.(C2017)

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    honokiol
    (Magnolia officinalis extract)

    1. Biological Activity And Toxicity Of The Chinese Herb Magnolia Officinalis Rehder & E. Wilson (Houpo) And Its Constituents
    2. Facile Purification Of Honokiol And Its Antiviral And Cytotoxic Properties
    3. Honokiol, A Lignan Biphenol Derived From The Magnolia Tree, Inhibits Dengue virus Type 2 Infection
    4. In Vitro Synergism Of Magnolol And Honokiol In Combination With Antibacterial Agents Against Clinical Isolates Of Methicillin-Resistant Staphylococcus Aureus …
    5. Inhibition Of Herpes Simplex virus -1 Replication By Natural Compound Honokiol
    6. Magnolol And Honokiol From Magnolia Officinalis Enhanced Antiviral Immune Responses Against Grass Carp Reovirus In Ctenopharyngodon Idella Kidney Cells
    7. Multiple Effects Of Honokiol On The Life Cycle Of Hepatitis C virus
    8. Neuroprotective Effect Of Natural Products Against Alzheimer’S Disease
    9. Phytochemicals And Pi3K Inhibitors In Cancer—An Insight
    10. Synthesis, Cytotoxicity, And Antiviral Activities Of New Neolignans Related To Honokiol And Magnolol


    houttuynia cordata extract
    (Houttuynia cordata Thunb)

    1. A Current Update On The Phytopharmacological Aspects Of Houttuynia Cordata Thunb
    2. Anti-Enterovirus 71 Activity Screening Of Chinese Herbs With Anti-Infection And Inflammation Activities
    3. Antimicrobial Dyeing Of Cotton And Silk Fabrics Using Houttuynia Cordata Extract
    4. Basic Veterinary Science Bvs-207 Virucidal Efficacy Of Clinacanthus Nutans And Houttuynia Cordata Extract Against Virulent Newcastle Disease virus
    5. Down-Regulation Of Fcϵri Expression By Houttuynia Cordata Thunb Extract In Human Basophilic Ku812F Cells
    6. Hepatoprotective Effect Of Houttuynia Cordata Thunb Extract Against Carbon Tetrachloride-Induced Hepatic Damage In Mice
    7. Houttuynia Cordata Thunb Inhibits The Production Of Pro‑Inflammatory Cytokines Through Inhibition Of The Nfκb Signaling Pathway In Hmc‑1 Human Mast Cells
    8. Houttuynia Cordata Thunb. And Its Bioactive Compound 2-Undecanone Significantly Suppress Benzo(A)Pyrene-Induced Lung Tumorigenesis By Activating The …
    9. Houttuynia Cordata Thunb: A Review Of Phytochemistry And Pharmacology And Quality Control
    10. Increased Flavonoid Compounds From Fermented Houttuynia Cordata Using Isolated Six Of Bacillus From Traditionally Fermented Houttuynia Cordata
    11. Preventive Effects Of Houttuynia Cordata Extract For Oral Infectious Diseases
    12. The Effect Of Houttuynia Cordata Injection On Pseudorabies Herpesvirus (Prv) Infection In Vitro


    Hypericin
    (Forsythia suspensaExtract)

    1. Antiviral Activity Of A Derivative Of The Photosensitive Compound Hypericin
    2. Antiviral Activity Of The Photoactive Plant Pigment Hypericin
    3. Antiviral Effect On H5N1 Avian Influenza virus Of Compound Of Curcuma Zedoaria Volatile Oil And Hypericin Perforatum Extract Liquid.
    4. Chemiluminescent Activation Of The Antiviral Activity Of Hypericin: A Molecular Flashlight
    5. Effect Of Hypericin On Influenza virus H9N2 In Vitro [J]
    6. Excited-State Processes In Polycyclic Quinones: The Light-Induced Antiviral Agent, Hypocrellin, And A Comparison With Hypericin
    7. Experimental Study On The Treatment Of Duck virus Hepatitis With Hypericin Oral Liquid
    8. Hypericin Inhibits Hepatitis C virus Replication Via Deacetylation And Down-Regulation Of Heme Oxygenase-1
    9. Hypericin, Hypocrellin, And Model Compounds: Primary Photoprocesses Of Light-Induced Antiviral Agents
    10. Hypericin-A New Antiviral And Antitumor Photosensitizer: Mechanism Of Action And Interaction With Biological Macromolecules
    11. Inactivation Of The Human Immunodeficiency virus By Hypericin: Evidence For Photochemical Alterations Of P24 And A Block In Uncoating
    12. Inhibition Of Duck Hepatitis B virus Replication By Hypericin
    13. Interaction Of A New Antiviral And Antitumor Photosensitizer Hypericin With Human Serum Albumin: Molecular Modeling Study
    14. Light-Induced Acidification By The Antiviral Agent Hypericin
    15. Observation Of Excited-State Tautomerization In The Antiviral Agent Hypericin And Identification Of Its Fluorescent Species
    16. Pharmacokinetics, Safety, And Antiviral Effects Of Hypericin, A Derivative Of St. John’S Wort Plant, In Patients With Chronic Hepatitis C virus Infection
    17. Photodynamic Inactivation Of Infectivity Of Human Immunodeficiency virus And Other Enveloped virus es Using Hypericin And Rose Bengal: Inhibition Of Fusion And …
    18. Photodynamic Inactivation Of Radiation Leukemia virus Produced From Hypericin-Treated Cells
    19. Photophysics And Light Induced Photobiology Of Antiviral And Antitumor Agents, Hypericin And Hypocrellin
    20. Photosensitization Is Required For Inactivation Of Equine Infectious Anemia virus By Hypericin
    21. Protective Effects Of Hypericin Against Infectious Bronchitis virus Induced Apoptosis And Reactive Oxygen Species In Chicken Embryo Kidney Cells
    22. Raman Spectroscopic Study On Structure Of Human Immunodeficiency virus (Hiv) And Hypericin-Induced Photosensitive Damage Of Hiv
    23. Strategies For Evaluation Of Enveloped virus Inactivation In Red Cell Concentrates Using Hypericin
    24. Studies On The Inhibitory Effects Of Hypericin On The Adsorption Ability Of Foot-And-Mouth virus To Host Cells In Vitro
    25. Study On Hypericin Soluble Powder Against Canine Distemper virus In Vitro.
    26. Study On The Antiviral Activity Of Hypericin Proteinbound Complex On H5N1 Subtype Of Aiv In Vitro
    27. Study On The Effect Of Hypericin Protein-Bound Complex Against H9N2 Subtype Of Avian Influenza virus In Chicken [J]
    28. The Antiviral Agent Hypericin Has In Vitro Activity Against Hsv-1 Through Non-Specific Association With viral And Cellular Membranes
    29. The Effects Of Hypericin On Inhibition Of Hepatitis B virus Replication In Vitro
    30. The Role Of Oxygen In The Antiviral Activity Of Hypericin And Hypocrellin
    31. The Role Of Oxygen In The Photoinduced Antiviral Activity Of Hypericin
    32. Therapeutic Efficacy Of Hypericin Powder For Chicken Infected With Infectious Bursal Disease virus .
    33. Ultrafast Excited-State Processes In The Antiviral Agent Hypericin

    ” alt=”” width=”379″ height=”261″ data-src=”https://theinterstellarplan.com/wp-content/uploads/2020/07/Isochavicine.jpg” />

    Isochavicine
    (pepper extract)

    1. Antiradical Properties Of Essential Oils And Extracts From Coriander, Cardamom, White, Red, And Black Peppers
    2. Piperine: A Comprehensive Review Of Methods Of Isolation, Purification And Biological Properties
    3. Evaluation of Traditional Ayurvedic Preparation for Prevention and Management of the Novel Coronavirus (SARS-CoV-2) Using Molecular Docking Approach

    ” alt=”” width=”515″ height=”379″ data-src=”https://theinterstellarplan.com/wp-content/uploads/2020/07/isoliquiritigenin.jpg” />
    isoliquiritigenin
    (glycyrrhiza uralensisfisch root)

    1. Anti-Caries Effect Of The Glycyrrhiza Uralensis Extract
    2. Assessment Report On Glycyrrhiza Glabra L. And/Or Glycyrrhiza Inflata Bat. And/Or Glycyrrhiza Uralensis Fisch., Radix
    3. Bioactive Constituents Of Glycyrrhiza Uralensis (Licorice): Discovery Of The Effective Components Of A Traditional Herbal Medicine
    4. Effects Of Post-Harvest Storage And Drying Temperatures On Four Medicinal Compounds In The Root Of Chinese Licorice (Glycyrrhiza Uralensis)
    5. Hmgr, Sqs, Β-As, And Cytochrome P450 Monooxygenase Genes In Glycyrrhiza Uralensis
    6. Integrated Morphology Analysis, Metabolomic Analysis And Gene Expression To Assess The Quality Of Four Adventitious Roots Lines Of Glycyrrhiza Uralensis Fisch
    7. Microcolumn Hplc-Uv Analysis Of Glycyrrhiza Uralensis And Licorice Preparations
    8. Overexpressing Chalcone Synthase (Chs) Gene Enhanced Flavonoids Accumulation In Glycyrrhiza Uralensis Hairy Roots
    9. Phenolic Compounds From Cultivated Glycyrrhiza Uralensis And Their Pd-1/Pd-L1 Inhibitory Activities
    10. Preparative Separation Of Liquiritigenin And Glycyrrhetic Acid From Glycyrrhiza Uralensis Fisch Using Hydrolytic Extraction Combined With High‐Speed Countercurrent …
    11. Quality Analysis Of Raw And Honey-Processed Licorice Of Glycyrrhiza Uralensis Fisch, And G. Glabra L. By Simultaneous Determination Of Five Bioactive Components …
    12. The Antiviral And Antimicrobial Activities Of Licorice, A Widely-Used Chinese Herb
    13. The Flavonoid Isoliquiritigenin Reduces Lung Inflammation And Mouse Morbidity During Influenza virus Infection
    14. The Protective Effects Of Isoliquiritigenin And Glycyrrhetinic Acid Against Triptolide-Induced Oxidative Stress In Hepg2 Cells Involve Nrf2 Activation

    ” alt=”” width=”427″ height=”449″ data-src=”https://theinterstellarplan.com/wp-content/uploads/2020/07/Isopiperine.jpg” />
    Isopiperine
    (pepper extract)

    1. Antiradical Properties Of Essential Oils And Extracts From Coriander, Cardamom, White, Red, And Black Peppers
    2. Antiviral Activity Of The Crude N-Hexane Extract From Leaves Of Piper Lepturum Var. Angustifolium (C. Dc.) Yunck.(Piperaceae)
    3. Piperine: A Comprehensive Review Of Methods Of Isolation, Purification And Biological Properties

    ” alt=”” width=”440″ height=”416″ data-src=”https://theinterstellarplan.com/wp-content/uploads/2020/07/Isothymonin.jpg” />
    Isothymonin
    (Kaempferia galanga L)

    1. Callus Induction And Cell Line Establishment From Various Explants Of Kaempferia Galanga
    2. Chemical Composition And Biological Activity Of Essential Oil Of Kaempferia Galanga: A Review
    3. Comparative Chemical Study Of Two Varieties Of Attractive Medicinal Plant Kaempferia Galanga Linn.
    4. Holy Basil: Holy Herb To Multimodal Medicine For Human Health
    5. Hypopigmentary Effects Of Ethyl P‐Methoxycinnamate Isolated From Kaempferia Galanga
    6. In Vivo Cytotoxic And In Vitro Antibacterial Activities Of Kaempferia Galanga
    7. Ocimum Sanctum And Its Effect On Oral Health–A Comprehensive Review.
    8. Traditional Indian Medicines Used For The Management Of Diabetes Mellitus

    ” alt=”” width=”353″ height=”235″ data-src=”https://theinterstellarplan.com/wp-content/uploads/2020/07/Jatrorrhizine.jpg” data-srcset=”https://theinterstellarplan.com/wp-content/uploads/2020/07/Jatrorrhizine.jpg 1024w, https://theinterstellarplan.com/wp-content/uploads/2020/07/Jatrorrhizine-500×333.jpg 500w, https://theinterstellarplan.com/wp-content/uploads/2020/07/Jatrorrhizine-300×200.jpg 300w, https://theinterstellarplan.com/wp-content/uploads/2020/07/Jatrorrhizine-768×512.jpg 768w, https://theinterstellarplan.com/wp-content/uploads/2020/07/Jatrorrhizine-219×146.jpg 219w, https://theinterstellarplan.com/wp-content/uploads/2020/07/Jatrorrhizine-50×33.jpg 50w, https://theinterstellarplan.com/wp-content/uploads/2020/07/Jatrorrhizine-113×75.jpg 113w” data-sizes=”(max-width: 353px) 100vw, 353px” />
    Jatrorrhizine
    (Phellodendron amurense Rupr.)

    1. 18 Biological Fingerprinting Analysis: Strategy For Screening Bioactive Compounds In Traditional Chinese Medicines
    2. 7.2 Heat-Clearing And Damp-Drying Herbs
    3. Antifungal Efficacy Of Phellodendron Amurense Ethanol Extract Against Trichophyton Mentagrophytes In Rabbits.
    4. Antiviral Activity Of Berberine
    5. Arbuscular Mycorrhizal Symbiosis And Active Ingredients Of Medicinal Plants: Current Research Status And Prospectives
    6. Berberine And Its Derivatives: A Patent Review (2009–2012)
    7. Biological Fingerprinting Analysis Of Traditional Chinese Medicines With Targeting Adme/Tox Property For Screening Of Bioactive Compounds By Chromatographic And …
    8. Capillary‐Hplc With Tandem Mass Spectrometry In Analysis Of Alkaloid Dyestuffs–A New Approach
    9. Chemical Composition And Antibacterial Activity Of The Essential Oil Of Phellodendron Lavallei
    10. Identification And Analysis Of Alkaloids In Cortex Phellodendron Amurense By High‐Performance Liquid Chromatography With Electrospray Ionization Mass Spectrometry …
    11. Palmatine: A Review Of Its Pharmacology, Toxicity And Pharmacokinetics
    12. Phellodendri Cortex: A Phytochemical, Pharmacological, And Pharmacokinetic Review
    13. Potential Of Dna Intercalating Alkaloids And Other Plant Secondary Metabolites Against Sars-Cov-2 Causing Covid-19
    14. Quantitative And Chemical Fingerprint Analysis For Quality Evaluation Of The Dried Bark Of Wild Phellodendron Amurense Rupr. Based On Hplc-Dad-Ms Combined With …
    15. Screening And Analysis Of Bioactive Compounds With Biofingerprinting Chromatogram Analysis Of Traditional Chinese Medicines Targeting Dna By Microdialysis/Hplc
    16. The Protective Effect On Ulcerative Colitis Of San Huang Shu’Ai Decoction By Inhibited The Il-1Β And Telomerase

    ” alt=”” width=”373″ height=”412″ data-src=”https://theinterstellarplan.com/wp-content/uploads/2020/07/Jujuboside-A.jpg” />
    Jujuboside A+B
    (Jujube extract)

    1. Bioactive Compounds From Ziziphus Jujuba And Allied Species
    2. Hypnotic Effect Of Coriandrum Sativum, Ziziphus Jujuba, Lavandula Angustifolia And Melissa Officinalis Extracts In Mice

    ” alt=”” width=”271″ height=”283″ data-src=”https://theinterstellarplan.com/wp-content/uploads/2020/07/Kaempferol.jpg” />
    Kaempferol
    (kaempferol galanga L)

    1. Antibacterial Action Of Tryptanthrin And Kaempferol, Isolated From The Indigo Plant (Polygonum Tinctorium Lour.), Against Helicobacter Pylori-Infected Mongolian …
    2. Antibacterial And Antioxidant Activities Of Four Kaempferol Methyl Ethers Isolated From Dodonaea Viscosa Jacq. Var. Angustifolia Leaf Extracts
    3. Anti-Japanese-Encephalitis-viral Effects Of Kaempferol And Daidzin And Their Rna-Binding Characteristics
    4. Antinociceptive And Anti-Inflammatory Kaempferol Glycosides From Sedum Dendroideum
    5. Content Of The Flavonols Myricetin, Quercetin, And Kaempferol In Finnish Berry Wines
    6. Cytotoxic Activity Of Kaempferol Glycosides Against Human Leukaemic Cell Lines In Vitro
    7. Determination Of Quercetin And Kaempferol In Human Urine After Orally Administrated Tablet Of Ginkgo Biloba Extract By Hplc
    8. Discordant Activity Of Kaempferol Towards Dengue virus And Japanese Encephalitis virus
    9. Dna Interaction With Naturally Occurring Antioxidant Flavonoids Quercetin, Kaempferol, And Delphinidin
    10. Evaluation Of The Antiviral Activity Of Kaempferol And Its Glycosides Against Human Cytomegalovirus
    11. Hepatoprotective Effects Of Kaempferol 3-O-Rutinoside And Kaempferol 3-O-Glucoside From Carthamus Tinctorius L. On Ccl4-Induced Oxidative Liver Injury In …
    12. In Vitro Anti-Hiv-1 Activities Of Kaempferol And Kaempferol-7-O-Glucoside Isolated From Securigera Securidaca
    13. In Vitro Glucuronidation Of Kaempferol And Quercetin By Human Ugt-1A9 Microsomes
    14. Involvement Of Kaempferol In The Defence Response Of virus Infected Arabidopsis Thaliana
    15. Kaempferol Acetylrhamnosides From The Rhizome Of Dryopteris Crassirhizoma And Their Inhibitory Effects On Three Different Activities Of Human Immunodeficiency virus -1 …
    16. Kaempferol Ameliorates H9N2 Swine Influenza virus -Induced Acute Lung Injury By Inactivation Of Tlr4/Myd88-Mediated Nf-Κb And Mapk Signaling Pathways
    17. Kaempferol Attenuates Acute Lung Injury In Mice Induced By Swine-Origin Influenza A H9 N2 virus Via Down-Regulation Of Nf-Κb Signaling Pathway
    18. Kaempferol Derivatives As Antiviral Drugs Against The 3A Channel Protein Of Coronavirus
    19. Kaempferol Induced Apoptosis Via Endoplasmic Reticulum Stress And Mitochondria‐Dependent Pathway In Human Osteosarcoma U‐2 Os Cells
    20. Kaempferol Induces Apoptosis In Glioblastoma Cells Through Oxidative Stress
    21. Kaempferol Induces Cell Death Through Erk And Akt-Dependent Down-Regulation Of Xiap And Survivin In Human Glioma Cells
    22. Kaempferol Inhibited Bovine Herpesvirus 1 Replication And Lps-Induced Inflammatory Response.
    23. Kaempferol Inhibits Enterovirus 71 Replication And Internal Ribosome Entry Site (Ires) Activity Through Fubp And Hnrp Proteins
    24. Kaempferol Inhibits Il‑1Β‑Induced Proliferation Of Rheumatoid Arthritis Synovial Fibroblasts And The Production Of Cox‑2, Pge2 And Mmps
    25. Kaempferol Inhibits Il-1Β-Stimulated, Rankl-Mediated Osteoclastogenesis Via Downregulation Of Mapks, C-Fos, And Nfatc1
    26. Kaempferol Inhibits Pseudorabies virus Replication In Vitro Through Regulation Of Mapks And Nf-Κb Signaling Pathways
    27. Metabolism Of Quercetin And Kaempferol By Rat Hepatocytes And The Identification Of Flavonoid Glycosides In Human Plasma
    28. Promoting Effect Of Kaempferol On The Differentiation And Mineralization Of Murine Pre-Osteoblastic Cell Line Mc3T3-E1
    29. Protective Effects Of Kaempferol On Isoniazid-And Rifampicin-Induced Hepatotoxicity
    30. The Roles Of Cdr1, Cdr2, And Mdr1 In Kaempferol-Induced Suppression With Fluconazole-Resistant Candida Albicans

    ” alt=”” width=”316″ height=”231″ data-src=”https://theinterstellarplan.com/wp-content/uploads/2020/07/Kaempferol-3-O-robinobioside..jpg” />
    Kaempferol 3-O-robinobioside
    (Robinia pseudoacacia L.)

    1. Antiviral Activities Of Indonesian Medicinal Plants In The East Java Region Against Hepatitis C virus
    2. Antiviral Effect Of Phytochemicals From Medicinal Plants: Applications And Drug Delivery Strategies
    3. Development Of Quality Control Parameters For The Standardization Of Gymnema Sylvestre
    4. Further Saponins And Flavonoids From Astragalus Verrucosus Moris
    5. Potent Antiviral Flavone Glycosides From Ficus Benjamina Leaves
    6. Quercetin And Quercetin 3-O-Glycosides From Bauhinia Longifolia (Bong.) Steud. Show Anti-Mayaro virus Activity
    7. The Journal Of Phytopharmacology

     

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Kolaviron

The outbreak of COVID-19 caused by SARS-CoV-2 is increasing with an alarming rate of associated frightening mortality without no known approved therapy. The emergence of new infectious diseases and increase in frequency of drug resistant viruses demand effective and novel therapeutic agents. This study investigated the putative inhibitory potentials of apigenin, fisetin, kolaflavanone, and remdesivir towards SARS-COV2 major protease (6LU7) using in silico methods. Pharmacodynamics, pharmacokinetics and toxicological profiles of the compounds were also examined using the pkCSM server. All the compounds showed good affinity to the binding pocket of 6LU7. It was observed that kolaflavanone exhibited the highest binding affinity when compared to apigenin, fisetin, and remdesivir. The amino acids ASN238, TYR237, LEU286, and LEU287 were showed as the key residues for kolaflavanone binding to human SARS-COV2 major protease. The Pharmacodynamics and pharmacokinetics results suggested that all the tested compounds have significant drug likeness properties and they could be absorbed through the human intestine. Additionally, all the tested compounds except remdesivir are not hepatoxic and also displayed non or relatively low toxic effects in human. Summarily, the results of this study indicated that all the tested compounds are potential putative inhibitors of SARS-COV2 major protease with no or low toxicity effects. However, further experimental and clinical studies are needed to further explore their activities and validate their efficacies against COVID-19.

  1. Kolaviron (Kolaflavanone), apigenin, fisetin as potential Coronavirus inhibitors: In silico investigation

 

 

    1. ” alt=”” width=”386″ height=”193″ data-src=”https://theinterstellarplan.com/wp-content/uploads/2020/07/leachianone.jpg” />
      leachianone
      (Morus alba root bark)

      1. A Review Of Ethnobotany, Phytochemistry, Antiviral And Cytotoxic/Anticancer Potential Of Morus Alba Linn
      2. Global Trends In Mulberry And Silkworm Use For Non–Textile Purposes
      3. Isolation And Characterization Of The Bioactive Phenolic Compounds From Morus Alba Leaves Growing In Egypt
      4. Multiple In Vitro Biological Effects Of Phenolic Compounds From Morus Alba Root Bark
      5. Phenolic Constituents From The Root Bark Of Morus Alba With Emphasis On Morusin And Its Anti-Cancer Properties
      6. Sanggenol L Promotes Apoptotic Cell Death In Melanoma Skin Cancer Cells Through Activation Of Caspase Cascades And Apoptosis-Inducing Factor
      7. Traditional Uses, Phytochemistry And Pharmacology Of Morus Alba Linn.: A Review

      ” alt=”” width=”341″ height=”348″ data-src=”https://theinterstellarplan.com/wp-content/uploads/2020/07/Lepidium-meyenii-.jpg” />
      Lepidium meyenii
      (maca extract)

      1. Antiviral Activity Of Maca (Lepidium Meyenii) Against Human Influenza virus
      2. Lepidium Meyenii (Maca)–Multidirectional Health Effects–Review
      3. Structure Analysis And Anti-Fatigue Activity Of A Polysaccharide From Lepidium Meyenii Walp
      4. Toxicological Aspects Of The South American Herbs Cat’S Claw (Uncaria Tomentosa) And Maca (Lepidium Meyenii)

      ” alt=”” width=”309″ height=”284″ data-src=”https://theinterstellarplan.com/wp-content/uploads/2020/07/Lilium-auratum.jpg” />
      Lily Extract
      (Lilium auratum)

      1. Antibacterial Properties Of White Lily (Lilium Candidum) Extract
      2. Antimicrobial Activity And Synergism Of Sami-Hyanglyun-Hwan With Ciprofloxacin Against Methicillin-Resistant Staphylococcus Aureus
      3. Biotechnological Advances In Lilium
      4. Chemistry And Biological Activity Of Steroidal Glycosides From The Lilium Genus
      5. Efficient One-Step Tissue Culture Protocol For Propagation Of Endemic Plant, Lilium Martagon Var. Cattaniae Vis.
      6. Evaluation Of Taste, Total Phenols And Antioxidant For Fresh, Roasted, Shade Dried And Boiled Leaves Of Edible Arum Palaestinum Bioss
      7. Guide To The Medicinal Plant Garden
      8. Isolation And Structural Determination Of Steroidal Glycosides From The Bulbs Of Easter Lily (Lilium Longiflorum Thunb.)
      9. The Effect Of Echinacea Purpurea, Astragalus Membranaceus And Glycyrrhiza Glabra On Cd69 Expression And Immune Cell Activation In Humans

      ” alt=”” width=”350″ height=”231″ data-src=”https://theinterstellarplan.com/wp-content/uploads/2020/07/luteoforol.jpg” data-srcset=”https://theinterstellarplan.com/wp-content/uploads/2020/07/luteoforol-219×146.jpg 219w, https://theinterstellarplan.com/wp-content/uploads/2020/07/luteoforol-50×33.jpg 50w, https://theinterstellarplan.com/wp-content/uploads/2020/07/luteoforol-112×75.jpg 112w, https://theinterstellarplan.com/wp-content/uploads/2020/07/luteoforol-1024×675.jpg 1024w” data-sizes=”(max-width: 350px) 100vw, 350px” />
      luteoforol (a flavan-4-ol)
      (Peanut shell extract)

      1. Antiherpetic Activity Of Some Endemic Hypericum Species In Turkey
      2. Anti-Infective Flavonoids: An Overview
      3. Antiviral Properties Of Phytochemicals
      4. Current Status Of Natural Products From Plants As Anti-Herpes Simplex virus 1 Agents
      5. Cytotoxicity, Antiviral And Antimicrobial Activities Of Alkaloids, Flavonoids, And Phenolic Acids
      6. Herpes virus Inhibitory Substances From Hypericum Connatum Lam., A Plant Used In Southern Brazil To Treat Oral Lesions
      7. Hypericum Caprifoliatum And Hypericum Connatum Affect Human Trophoblast-Like Cells Differentiation And Ca2+ Influx
      8. Inhibitory Effect Of Rhinacanthus Nasutus (Linn.) Kurz. And Stemona Tuberosa (Lour.) Extracts On Herpes Simplex virus Infection
      9. Phytochemical And Antimicrobial Studies Of Bridelia Crenulata
      10. Potentiality Of Red Sorghum For Producing Stilbenoid-Enriched Beers With High Antioxidant Activity
      11. The Genus Bridelia: A Phytochemical And Ethnopharmacological Review
      12. Unravelling Lead Antiviral Phytochemicals For The Inhibition Of Sars-Cov-2 Mpro Enzyme Through In Silico Approach

      Luteolin
      (Peanut shell extract)

      LUTeolin specifically binds to the surface spike protein of SARS‐Cov‐2 and inhibits entry of the virus into host cells.

      The new coronavirus (severe acute pulmonary syndrome [SARS]‐CoV‐2) originated in China, where it spread rapidly,1 and has reached pandemic proportions because of its high rate of infectivity as well as high morbidity and mortality, associated with COVID‐19.2 This coronavirus infects by first binding to the ectoenzyme angiotensin‐converting enzyme 2 (ACE2),3, 4 a serine protease acting as the receptor, while another serine protease is necessary for priming the viral “S” protein required for entering the cells.5 Defense against the virus apparently does not involve inflammatory cytokines,6 but pulmonary infection and its serious sequelae result from the release of multiple chemokines and cytokines that damage the lungs.

      A recent report correlated coronaviruses infection with activation of mast cells and subsequent cytokine storms in the lungs.7Mast cells are known to be triggered by viruses.8 Mast cells are unique immune cells that are ubiquitous in the body, especially the lungs,9 and are critical for allergic and pulmonary diseases,10 including mastocytosis11 by secreting histamine, leukotrienes, and proteases. Mast cells are also involved in the development of inflammation12 via release of multiple pro‐inflammatory cytokines and chemokines.13, 14

      Mast cells contain the serine protease ACE2, which can convert angiotensin I into angiotensin II.15 In addition to the bronchoconstrictive action of mast cell‐derived leukotrienes, mast cells cause further bronchoconstriction via an active renin‐angiotensin generating system in the lungs.16Moreover, mast cells express a number of serine proteases,17 especially the mast cell‐serine protease tryptase,18 which are necessary for infection by SARS‐CoV‐2. A serine protease inhibitor, camostat mesylate, was recently shown to prevent entry of the virus into the lung cells of SARS‐CoV‐2‐infected patients.19 It would be important to not only inhibit entry of SARS‐CoV‐2 but also prevent SARS associated with COVID‐19.

      The possible use of nonsteroidal anti‐inflammatory agents has come into question for possibly aggravating pulmonary symptoms,20 while broad‐spectrum immune suppressors, such as corticosteroids,21 would not be advisable given that an intact immune system is necessary to fight the infection and it may even lead to increased plasma viral load.22

      Inhibition of mast cell‐associated inflammation could be accomplished with natural molecules, especially the polyphenolic flavonoids.23 The flavone luteolin (not lutein, which is a carotenoid) has been shown to have broad antiviral properties.24–26 Luteolin specifically binds to the surface spike protein of SARS‐Cov‐2 and inhibits entry of the virus into host cells.27 Furthermore, luteolin inhibits serine proteases,28 including the SARS‐CoV 3CL protease29 required for viral infectivity.

      Moreover, luteolin inhibits mast cells30, 31and has anti‐inflammatory properties.32 A novel luteolin analogue, tetramethoxyluteolin, is even more potent32 and can also inhibit secretion of the pro‐inflammatory cytokines TNF and IL‐1β,33, 34 as well as the chemokines CCL2 and CCL535 from human mast cells.

      1. Antiviral Activity Of Luteolin Against Japanese Encephalitis virus
      2. Comparative Study Of Antiviral Activity Of Luteolin And 7, 3′-Disulfate Luteolin
      3. Effects Of Baicalin And Luteolin-7-O-Glucoside On Nf-Κb Signaling Pathway In A549 Cells Infected With Influenza virus H1N1 In Vitro
      4. Effects Of Orlistat And Herbal Mixture Extract On Brain, Testes Functions And Oxidative Stress Biomarkers In A Rat Model Of High Fat Diet
      5. Hplc Determination Of Luteoloside In Shuanghuanglian Injection
      6. In Vitro Anti Coxsackie B_3 virus Effect Of Luteolin
      7. Luteolin Decreases The Yield Of Influenza A virus In Vitro By Interfering With The Coat Protein I Complex Expression
      8. Luteolin Escape Mutants Of Dengue virus Map To Prm And Ns2B And Reveal viral Plasticity During Maturation
      9. Luteolin Inhibits Epstein-Barr virus Lytic Reactivation By Repressing The Promoter Activities Of Immediate-Early Genes
      10. Luteolin Inhibits Hepatitis B virus Replication Through Extracellular Signal-Regulated Kinase-Mediated Down-Regulation Of Hepatocyte Nuclear Factor 4Α Expression
      11. Luteolin Inhibits Respiratory Syncytial virus Replication By Regulating The Mir-155/Socs1/Stat1 Signaling Pathway
      12. Luteolin Restricts Dengue virus Replication Through Inhibition Of The Proprotein Convertase Furin

      Lycoris radiata
      (Lycoris radiata (L’Her.) Herb.)

      1. Amaryllidaceae And Sceletium Alkaloids
      2. Antibacterial Constituents Of The Plant Family Amaryllidaceae
      3. Aphicidal Activities Of Amaryllidaceae Alkaloids From Bulbs Of Lycoris Radiata Against Aphis Citricola
      4. Ficus Septica Plant Extracts For Treating Dengue virus In Vitro
      5. Therapeutic Potentials Of Herbal Drugs For Alzheimer’S Disease—An Overview
      6. Two New Amaryllidaceae Alkaloids From The Bulbs Of Lycoris Radiata


      Macaranga barteri extract
      (Macaranga barteri Leaves)

      1. In Vitro Antiviral Activity Of Twenty-Seven Medicinal Plant Extracts From Southwest Nigeria Against Three Serotypes Of Echovirus es

       

      Maclura cochinchinensis extract
      (Maclura cochinchinensis (Loureiro) Corner root)

      1. 13. Bio-Prospecting Of Plant Resources For Validation Of Indigenous Knowledge And The Search For Novel Herbal Drugs In Nepal
      2. A Validated Hptlc Method For Quantitative Analysis Of Morin In Maclura Cochinchinensis Heartwood
      3. Anti-Herpes Simplex virus Component Isolated From Maclura Cochinchinensis
      4. Antiviral Flavonoids From The Root Bark Of Morus Alba L.
      5. Asia Is The Mine Of Natural Antiviral Products For Public Health

      ” alt=”” width=”327″ height=”275″ data-src=”https://theinterstellarplan.com/wp-content/uploads/2020/07/Magnoflorine.jpg” />
      Magnoflorine
      (Thalictrum aquilegifolium root extract)

      1. A Novel Systems Pharmacology Platform To Dissect Action Mechanisms Of Traditional Chinese Medicines For Bovine viral Diarrhea Disease
      2. A Review Of The Most Important Native Medicinal Plants Of Iran Effective On Cutaneous Leishmaniasis In Mouse Model
      3. A Review On Ayurvedic Medicinal Herbs As Remedial Perspective For Covid-19
      4. Analysis Of Essential Oil From The Stem Of Chasmathera Dependens.
      5. Anti-Hiv Alkaloids From Toddalia Asiatica
      6. Antitumor And Antiviral Activities Of Magnolia Grandiflora L. Leaves Growing In Egypt
      7. Atural And Synthetic Hiv-1 Non-Nucleoside Reverse Transcriptase Inhibitors: A Theoretical Approach
      8. Chemical Constituents And Biological Activities Of The Genus Zanthoxylum: A Review
      9. Coptidis Rhizoma Extract Inhibits Replication Of Respiratory Syncytial virus In Vitro And In Vivo By Inducing Antiviral State
      10. Cytotoxic And Antiviral Activities Of Aporphine Alkaloids Of Magnolia Grandiflora L.
      11. Design And Development Of Anti-Hepatitis B virus Agents
      12. Drug Design For Hemagglutinin: Screening And Molecular Dynamics From Traditional Chinese Medicine Database
      13. Efficacy And Safety Of Yinqisanhuang-Antiviral Decoction In Chronic Hepatitis B: Study Protocol For A Randomized, Placebo-Controlled, Double-Blinded Trial
      14. Efficacy Of Natural Compounds From Tinospora Cordifolia Against Sars-Cov-2 Protease, Surface Glycoprotein And Rna Polymerase.
      15. Ethnomedicines Of Indian Origin For Combating Covid-19 Infection By Hampering The viral Replication: Using Structure-Based Drug Discovery Approach
      16. Evaluation Of Natural Products As Inhibitors Of Human Immunodeficiency virus Type
      17. In Silico Computational Screening Of Kabasura Kudineer-Official Siddha Formulation And Jacom Against Sars-Cov-2 Spike Protein
      18. Isoquinoline Alkaloids And Their Antiviral, Antibacterial, And Antifungal Activities And Structure-Activity Relationship
      19. Plant Antiviral Agents; Vi. 1 3-Methoxyflavones As Potent Inhibitors Of Viral-Induced Block Of Cell Synthesis
      20. Sulfated Modification Of Epimedium Polysaccharide And Effects Of The Modifiers On Cellular Infectivity Of Ibdv
      21. Toxicoderma Due To Rhizoma Coptidis
      22. Treatment Of Human Influenza A (H5N1) Infection With Ching-Wen-Bai-Du-Yin
      23. Two New Alkaloids And Active Anti-Hepatitis B virus Constituents From Hypserpa Nitida

      ” alt=”” width=”449″ height=”399″ data-src=”https://theinterstellarplan.com/wp-content/uploads/2020/07/Marrubium-peregrinum.jpeg” />
      Marrubium peregrinum L (Lamiaceae)
      (Marrubium peregrinum L)

      1. A Plant-Derived Flavonoid Inhibits Entry Of All Hcv Genotypes Into Human Hepatocytes
      2. Antioxidant Properties Of Marrubium Peregrinum L.(Lamiaceae) Essential Oil
      3. Hepatitis C virus And Natural Compounds: A New Antiviral Approach?
      4. Medicinal Plants Against Hepatitis C virus
      5. Validation Of Antiviral Potential Of Herbal Ethnomedicine

      Meliacine
      (Melia azedarach L)

      1. An Antiviral Principle Present In A Purified Fraction From Melia Azedarach L. Leaf Aqueous Extract Restrains Herpes Simplex virus Type 1 Propagation
      2. Antiviral Activity Of Meliacine On The Replication Of A Thymidine Kinase-Deficient Mutant Of Herpes Simplex virus Type 1 Alone And In Combination With Acyclovir
      3. Effect Of Meliacine, A Plant Derived Antiviral, On Tumor Necrosis Factor Alpha
      4. Inhibition Of Herpes Simplex virus Type-1 Multiplication By Meliacine, A Peptide Of Plant Origin
      5. Meliacine, An Antiviral Compound From Melia Azedarach L., Inhibits Interferon Production
      6. Purification And Partial Characterization Of An Antiviral Active Peptide From Melia Azedarach L.
      7. Therapeutic Action Of Meliacine, A Plant-Derived Antiviral, On Hsv-Induced Ocular Disease In Mice
      8. Therapeutic Effect Of Meliacine, An Antiviral Derived From Melia Azedarach L., In Mice Genital Herpetic Infection
      9. Treatment With Meliacine, A Plant Derived Antiviral, Prevents The Development Of Herpetic Stromal Keratitis In Mice


      Mint extract

      1. … Liquid Phase Microextraction Combined With High-Performance Liquid Chromatography For The Analysis Of Flavonoids In Echinophora Platyloba Dc. And Mentha Piperita
      2. A Review Of The Bioactivity And Potential Health Benefits Of Peppermint Tea (Mentha Piperita L.)
      3. Antibacterial And Antioxidant Activities Of Mentha Piperita L.
      4. Antifungal Activity Of Volatiles From Lemongrass (Cymbopogon Citratus) And Peppermint (Mentha Piperita) Oils Against Some Respiratory Pathogenic Species Of …
      5. Antimicrobial Activity Of Mentha Piperita And Saturenja Hortensis In A Murine Model Of Cutaneous Protothecosis
      6. Antimicrobial And Antiviral Effects Of Essential Oils From Selected Umbelliferae And Labiatae Plants And Individual Essential Oil Components
      7. Antinociception Effects Of Ethanolic Extract Of Mentha Piperita Leaves In Adult Male Mice
      8. Antiviral Effect Of The Lamiaceae Family Against Herpes Simplex
      9. Antiviral Effect Of Three Vegetal Infusions (Mentha Piperita, Cinnamomum Zeylanicum Blume And Ocimum Basilicum Lineo) On A Murine Herpetic Infection
      10. Antiviral Substances In Plants Of The Mint Family (Labiatae). Iii. Peppermint (Mentha Piperita) And Other Mint Plants.
      11. Chemical Composition And Anti-Inflammatory, Cytotoxic And Antioxidant Activities Of Essential Oil From Leaves Of Mentha Piperita Grown In China
      12. Chemical Composition, Antifungal And Antibiofilm Activities Of The Essential Oil Of Mentha Piperita L.
      13. Comparative In Vitro Anthelmintic Activity Of Chloroform And Acetone Extracts Of Mentha Piperita
      14. Composition, Antifungal Activity And Main Fungitoxic Components Of The Essential Oil Of Mentha Piperita L.
      15. Effects Of Dietary Peppermint (Mentha Piperita) On Growth Performance, Chemical Body Composition And Hematological And Immune Parameters Of Fry Caspian White …
      16. Elucidation Of The Synergistic Action Of Mentha Piperita Essential Oil With Common Antimicrobials
      17. Encapsulation Of Mentha Piperita Essential Oils In Chitosan–Cinnamic Acid Nanogel With Enhanced Antimicrobial Activity Against Aspergillus Flavus
      18. Extraction, Preliminary Characterization And Evaluation Of In Vitro Antitumor And Antioxidant Activities Of Polysaccharides From Mentha Piperita
      19. In Vitro And In Vivo Anti-Tobacco Mosaic Virus Activities Of Essential Oils And Individual Compounds
      20. In Vitro Antiviral, Anti-Inflammatory, And Antioxidant Activities Of The Ethanol Extract Of Mentha Piperita L.
      21. Inhibitory Effect Of Mentha Piperita Extracts Against Herpes Simplex Virus Isolated From Eye Infection
      22. Pharmacological Activities Of Mentha Piperita-Mini Review
      23. Preparative Separation Of Menthol And Pulegone From Peppermint Oil (Mentha Piperita L.) By High-Performance Counter-Current Chromatography
      24. Properties Of Mentha Piperita: A Brief Review
      25. Retention Of Aroma Compounds From Mentha Piperita Essential Oil By Cyclodextrins And Crosslinked Cyclodextrin Polymers
      26. The Inhibitory Effect Of Essential Oils On Herpes Simplex Virus Type‐1 Replication In Vitro
      27. The Role Of Peppermint (Mentha Piperita) On Performance In Broiler Diets
      28. Virucidal Effect Of Peppermint Oil On The Enveloped Viruses Herpes Simplex Virus Type 1 And Type 2 In Vitro

       

       

      ” alt=”” width=”275″ height=”183″ data-src=”https://theinterstellarplan.com/wp-content/uploads/2020/07/morroniside.jpg” data-srcset=”https://theinterstellarplan.com/wp-content/uploads/2020/07/morroniside.jpg 275w, https://theinterstellarplan.com/wp-content/uploads/2020/07/morroniside-219×146.jpg 219w, https://theinterstellarplan.com/wp-content/uploads/2020/07/morroniside-50×33.jpg 50w, https://theinterstellarplan.com/wp-content/uploads/2020/07/morroniside-113×75.jpg 113w” data-sizes=”(max-width: 275px) 100vw, 275px” />

      morroniside
      (Cornus officinalis extract (Fructus Corni))

      1. Cornus Officinalis Extract (Fru
      2. In Silico Screening Of Hepatitis C virus Ns3/4A Protease Inhibitor (S) From Cornus Officinalis And Syzygium Aromaticum.
      3. Determination Of Loganin In The Cornus Officinalis From Different Sources By Hplc [J]
      4. Effects Of Extract From Cornus Officinalis On Nitrc Oxide And Nf-Κβ In Cortex Of Cerebral Infarction Rat Model [J]
      5. Evaluation Of The Potential Hypoglycemic And Beta-Cell Protective Constituents Isolated From Corni Fructus To Tackle Insulin-Dependent Diabetes Mellitus
      6. Folium Sennae
      7. Immmunopharmacological Study Of The Total Glucoside Fraction From Cornus Officinalis: Ⅱ. In Vitro Suppressive Effect Of The …
      8. Iridoids Are Natural Glycation Inhibitors
      9. Longevity Depends On A Balance Between Proinflammatory And Anti-Inflammatory Factors: Use Of Tcms And Natural Products
      10. Recent Applications Of Capillary Electrophoresis In The Analysis Of Traditional Chinese Medicines
      11. Study On The Chemical Constituents From The Fruit Of Corni Fructus
      12. The Journal Of Phytopharmacology

      ” alt=”” width=”420″ height=”768″ data-src=”https://theinterstellarplan.com/wp-content/uploads/2020/07/myricetin.jpg” />
      myricetin
      (black Bayberry fruit)

      1. Bioassay-Guided Isolation Of Anti-Hepatitis B virus Flavonoid Myricetin-3-O-Rhamnoside Along With Quercetin From Guiera Senegalensis Leaves
      2. Identification Of Myricetin As An Ebola virus Vp35–Double-Stranded Rna Interaction Inhibitor Through A Novel Fluorescence-Based Assay
      3. Inhibition Of African Swine Fever virus Protease By Myricetin And Myricitrin
      4. Inhibition Of Herpes Simplex virus By Myricetin Through Targeting viral Gd Protein And Cellular Egfr/Pi3K/Akt Pathway
      5. Synthesis And Antibacterial And Antiviral Activities Of Myricetin Derivatives Containing A 1, 2, 4-Triazole Schiff Base
      6. Synthesis And Antiviral Activity Of Novel Myricetin Derivatives Containing Ferulic Acid Amide Scaffolds

       

      ” alt=”” width=”351″ height=”235″ data-src=”https://theinterstellarplan.com/wp-content/uploads/2020/07/naringenin-.jpg” data-srcset=”https://theinterstellarplan.com/wp-content/uploads/2020/07/naringenin-.jpg 1300w, https://theinterstellarplan.com/wp-content/uploads/2020/07/naringenin–500×333.jpg 500w, https://theinterstellarplan.com/wp-content/uploads/2020/07/naringenin–300×200.jpg 300w, https://theinterstellarplan.com/wp-content/uploads/2020/07/naringenin–768×512.jpg 768w, https://theinterstellarplan.com/wp-content/uploads/2020/07/naringenin–1024×682.jpg 1024w, https://theinterstellarplan.com/wp-content/uploads/2020/07/naringenin–219×146.jpg 219w, https://theinterstellarplan.com/wp-content/uploads/2020/07/naringenin–50×33.jpg 50w, https://theinterstellarplan.com/wp-content/uploads/2020/07/naringenin–113×75.jpg 113w” data-sizes=”(max-width: 351px) 100vw, 351px” />

      naringenin
      (Amacardi-um occidentale L.))

      1. Apolipoprotein B–Dependent Hepatitis C virus Secretion Is Inhibited By The Grapefruit Flavonoid Naringenin
      2. Corrigendum: The Citrus Flavanone Naringenin Impairs Dengue virus Replication In Human Cells
      3. Effect Of Naringenin On The Replication Of Herpes Simplex virus
      4. Effect Of Naringenin, Hesperetin And Their Glycosides Forms On The Replication Of The 17D Strain Of Yellow Fever virus
        In Vitro Antiviral Activity Of Fisetin, Rutin And Naringenin Against Dengue virus Type-2
      5. Inhibition Of Chikungunya virus Replication By Hesperetin And Naringenin
      6. Naringenin Ameliorates Insulin Resistance By Modulating Endoplasmic Reticulum Stress In Hepatitis C virus -Infected Liver
      7. Naringenin Attenuates Hepatitis B virus X Protein-Induced Hepatic Steatosis
      8. Naringenin Improve Hepatitis C virus Infection Induced Insulin Resistance By Increase Pten Expression Via P53-Dependent Manner
      9. Naringenin Inhibits The Assembly And Long-Term Production Of Infectious Hepatitis C virus Particles Through A Ppar-Mediated Mechanism
      10. Naringenin, A Flavanone With Antiviral And Anti‐Inflammatory Effects: A Promising Treatment Strategy Against Covid‐19
      11. The Citrus Flavanone Naringenin Impairs Dengue virus Replication In Human Cells
      12. The Citrus Flavonoid Naringenin Impairs The In Vitro Infection Of Human Cells By Zika virus
      13. The Grapefruit Flavonoid Naringenin As A Hepatitis C virus Therapy: Efficacy, Mechanism And Delivery

      ” alt=”” width=”286″ height=”256″ data-src=”https://theinterstellarplan.com/wp-content/uploads/2020/07/ndoxyl-β-glucoside.jpg” />

      ndoxyl-β-glucoside
      (Radix isatidis P.E (satis tinctoria L. Isatis indigotica Fort.))

      1. Antiviral glycosidic bisindole alkaloids from the roots of Isatis indigotica

      2. Antiviral enantiomers of a bisindole alkaloid with a new carbon skeleton from the roots of Isatis indigotica

      3. Indole alkaloid sulfonic acids from an aqueous extract of Isatis indigotica roots and their antiviral activity

      4. Evaluation on antiendotoxic action and antiviral action in vitro of tetraploid Isatis indigotica

      5. Antiviral stereoisomers of 3, 5-bis (2-hydroxybut-3-en-1-yl)-1, 2, 4-thiadiazole from the roots of Isatis indigotica

      6.  Aromatic compounds from an aqueous extract of “ban lan gen” and their antiviral activities

      ” alt=”” width=”459″ height=”427″ data-src=”https://theinterstellarplan.com/wp-content/uploads/2020/07/nothofagin.jpg” />
      nothofagin
      (Aspalathus Linearis)

      1. A Kinetic And Equilibrium Study Of Rooibos Tea Infusions.
      2. A Review Of The Bioactivity Of South African Herbal Teas: Rooibos (Aspalathus Linearis) And Honeybush (Cyclopia Intermedia)
      3. Antioxidant Properties Of Rooibos (Aspalathus Linearis)–In Vitro And In Vivo Evidence
      4. Antioxidants Of Rooibos Tea-A Possible Explanation For Its Health Promoting Properties?
      5. Antiviral Activity Of Aspalathus Linearis Against Human Influenza virus
      6. Aspalathin A Unique Phytochemical From The South African Rooibos Plant (Aspalathus Linearis): A Mini Review
      7. Development Of A Sensory Lexicon And Sensory Wheel For Rooibos (Aspalathus Linearis) And The Role Of Its Phenolic Composition On Taste And Mouthfeel.
      8. Hepatotoxicity Due To Red Bush Tea Consumption: A Case Report
      9. Identification Of Phenolic Compounds In Aqueous And Ethanolic Rooibos Extracts (Aspalathus Linearis) By Hplc-Esi-Ms (Tof/It)
      10. Rooibos Tea As A Likely Health Food Supplement
      11. Rooibos Tea Extracts Inhibit Osteoclast Formation And Activity Through The Attenuation Of Nf-Κb Activity In Raw264. 7 Murine Macrophages
      12. Rooibos Tea: New Research Documents Antioxidant And Anticancer Properties
      13. Rooibos Tea: Research Into Antioxidant And Antimutagenic Properties
      14. The Effects Of Rooibos (Aspalathus Linearis), Green Tea (Camellia Sinensis) And Commercial Rooibos And Green Tea Supplements On Epididymal Sperm In …
      15. Traditional Medicines In Africa: An Appraisal Of Ten Potent African Medicinal Plants

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      Oleanolic acid
      (olea europaea l.leaves extract)

      1. Antiviral Activities Of Oleanolic Acid And Its Analogues
      2. Antiviral Effects Of Oleanolic Acid On Guniea Cytomegalovirus In Vitro

      ” alt=”” width=”300″ height=”260″ data-src=”https://theinterstellarplan.com/wp-content/uploads/2020/07/Olomoucine-II.jpg” data-srcset=”https://theinterstellarplan.com/wp-content/uploads/2020/07/Olomoucine-II.jpg 300w, https://theinterstellarplan.com/wp-content/uploads/2020/07/Olomoucine-II-168×146.jpg 168w, https://theinterstellarplan.com/wp-content/uploads/2020/07/Olomoucine-II-50×43.jpg 50w, https://theinterstellarplan.com/wp-content/uploads/2020/07/Olomoucine-II-87×75.jpg 87w” data-sizes=”(max-width: 300px) 100vw, 300px” />
      Olomoucine II

      1. Olomoucine II, specific inhibitor of cyclin dependent kinases, as antiviral drug.
      2. The inhibitor of cyclin-dependent kinases, olomoucine II, exhibits potent antiviral properties

      ” alt=”” width=”355″ height=”186″ data-src=”https://theinterstellarplan.com/wp-content/uploads/2020/07/ophiocarpine-.jpg” />

      ophiocarpine
      (Corydalis ophiocarpa Hook. f. et Thoms)

      1. A Perspective On The Anti-Infective Activity Of Goldenseal (Hydrastis Canadensis) And Its Contribution To The Development Of Multidrug Pump Inhibitors
      2. Anti-Hepatitis B Activity Of Isoquinoline Alkaloids Of Plant Origin
      3. Antiviral And Antimicrobial Profiles Of Selected Isoquinoline Alkaloids From Fumaria And Corydalis Species
      4. Cytotoxicity, Antiviral And Antimicrobial Activities Of Alkaloids, Flavonoids, And Phenolic Acids
      5. Plant Alkaloids: Classification, Isolation, And Drug Development

      ” alt=”” width=”286″ height=”300″ data-src=”https://theinterstellarplan.com/wp-content/uploads/2020/07/ophiopogonin-A.jpg” data-srcset=”https://theinterstellarplan.com/wp-content/uploads/2020/07/ophiopogonin-A.jpg 286w, https://theinterstellarplan.com/wp-content/uploads/2020/07/ophiopogonin-A-139×146.jpg 139w, https://theinterstellarplan.com/wp-content/uploads/2020/07/ophiopogonin-A-48×50.jpg 48w, https://theinterstellarplan.com/wp-content/uploads/2020/07/ophiopogonin-A-72×75.jpg 72w” data-sizes=”(max-width: 286px) 100vw, 286px” />
      ophiopogonin A
      (Ophiopogon Root Extract)

      1. Traditional Chinese Herbal Medicine As A Source Of Molecules With Antiviral Activity
      2. The Role Of Standardized Herbal Formulas In Contemporary Healthcare Delivery
      3. The Optimization Of Sulfation Modification Conditions For Ophiopogonpolysaccharide Based On Antiviral Activity
      4. Study On Biodiversity And Feature Of Enzyme Excreting About Endophytic Actinomycetes Isolated From Ophiopogon Japonicus Ker-Gawl. And Gynura Japonica Juel.[J]
      5. Studies On Antiviral Activities Of Polysaccharides And Their Derivatives [J]
      6. Structure And Bioactivities Of Saponin And Its Application In Aquaculture
      7. Purification, Characterization And Molecular Cloning Of A Novel Mannose-Binding Lectin From Rhizomes Of Ophiopogon Japonicus With Antiviral And Antifungal Activities
      8. Preparation And Biological Activity Of Saponin From Ophiopogon Japonicus
      9. Potent Antiviral Activity Of Carbohydrate-Specific Algal And Leguminous Lectins From The Brazilian Biodiversity
      10. Polygonatum Cyrtonema Lectin Induces Murine Fibrosarcoma L929 Cell Apoptosis Via A Caspase-Dependent Pathway As Compared To Ophiopogon Japonicus Lectin
      11. Ophiopogon Polysaccharide Liposome Can Enhance The Non-Specific And Specific Immune Response In Chickens
      12. Bioinformatics Analyses Of The Mannose-Binding Lectins From Polygonatum Cyrtonema, Ophiopogon Japonicus And Liparis Noversa With Antiproliferative And Apoptosis …
      13. Antitumor Activity Of Bacterial Exopolysaccharides From The Endophyte Bacillus Amyloliquefaciens Sp. Isolated From Ophiopogon Japonicus
      14. Antioxidative And Immunological Activities Of Ophiopogon Polysaccharide Liposome From The Root Of Ophiopogon Japonicus
      15. A New Steroidal Saponin From The Tubers Of Ophiopogon Japonicus And Its Protective Effect Against Cisplatin-Induced Renal Cell Toxicity


      Orientin
      (Globeflower Extract)

      1. Elucidating The Effects Of Orientin And Madecassoside On Saffold virus Infection In Bv2 Microglial And Ne-4C Neural Stem Cells


      oxypeucedanin
      (Angelica dahurica Extract)

      1. Analgesic And Anti-Inflammatory Effect Of The Aqueous Extract Of Angelica Dahurica
      2. Anti-Inflammatory Coumarins With Short-And Long-Chain Hydrophobic Groups From Roots Of Angelica Dahurica Cv. Hangbaizhi
      3. Antiviral Activity Of Furanocoumarins Isolated From Angelica Dahurica Against Influenza A virus es H1N1 And H9N2
      4. Chemical Constituents In Roots Of Angelica Dahurica Var. Formosana [J]
      5. First Report Of Cucumber Mosaic virus Infecting Bahizi (Angelica Dahurica) In China

      ” alt=”” width=”441″ height=”396″ data-src=”https://theinterstellarplan.com/wp-content/uploads/2020/07/paeoniflorin.jpg” />
      paeoniflorin
      (Radix Paeoniae Rubra extract)

      1. Blockade Of Paeoniflorin On L-Type Calcium Channel In Isolated Rat Ventricular Myocytes
      2. Content Determination Of The Paeoniflorin In Baobaole Granule By Hplc
      3. Determination Of Paeoniflorin In Huayuquban Tablets With Hplc Method
      4. Determination Of Paeoniflorin In Weishukang Tablets By Hplc Method [J]
      5. Determination The Content Of Paeoniflorin In Libiling Tablets By Hplc
      6. Effects Of Glycyrrhizin On The Pharmacokinetics Of Paeoniflorin In Rats And Its Potential Mechanism
      7. Paeonia Lactiflora
      8. Paeoniflorin Ameliorates Interferon-Alpha-Induced Neuroinflammation And Depressive-Like Behaviors In Mice
      9. Paeoniflorin Promotes Angiogenesis And Tissue Regeneration In A Full‐Thickness Cutaneous Wound Model Through The Pi3K/Akt Pathway
      10. Paeoniflorin Protects Against Liver Ischemia/Reperfusion Injury In Mice Via Inhibiting Hmgb1‐Tlr4 Signaling Pathway
      11. Paeoniflorin, A Novel Heat Shock Protein–Inducing Compound
      12. Study On The Dynamic Change Of Paeoniflorin Content From Three Herbaceous Peony Cultivars [J]
      13. Study The Serum Pharmacological Effects Of Paeoniflorin On Proliferation Of Bel-7420 Cells In Human Hepctocellular Carcinoma
      14. Synthesis, Characterization And In Vitro Dna Binding Studies Of A New Copper(Ii) Complex Containing An Antiviral Drug, Valganciclovir
      15. Uplc–Ms/Ms Determination Of Paeoniflorin, Naringin, Naringenin And Glycyrrhetinic Acid In Rat Plasma And Its Application To A Pharmacokinetic Study After Oral …

      ” alt=”” width=”300″ height=”188″ data-src=”https://theinterstellarplan.com/wp-content/uploads/2020/07/Patrinia-villosa-Juss.jpg” data-srcset=”https://theinterstellarplan.com/wp-content/uploads/2020/07/Patrinia-villosa-Juss.jpg 300w, https://theinterstellarplan.com/wp-content/uploads/2020/07/Patrinia-villosa-Juss-233×146.jpg 233w, https://theinterstellarplan.com/wp-content/uploads/2020/07/Patrinia-villosa-Juss-50×31.jpg 50w, https://theinterstellarplan.com/wp-content/uploads/2020/07/Patrinia-villosa-Juss-120×75.jpg 120w” data-sizes=”(max-width: 300px) 100vw, 300px” />
      Patrinia villosa Juss. extract
      (Patrinia villosa (Thunb. ) Juss.)

      1. Antiviral Chinese Medicinal Herbs Against Respiratory Syncytial virus
      2. Evaluation To The Antifungal Activity Of Total Flavonoids Extract From Patrinia Villosa Juss And Optimization By Response Surface Methodology
      3. In Vitro Antiviral Activities Of Chinese Medicinal Herbs Against Duck Hepatitis B virus
      4. Screening Of Antiviral Medicinal Plants Against Avian Influenza virus H1N1 For Food Safety
      5. Studies On Anti-Tumor Activity In Vitro Of Laricircsinol From Patrinia Villosa Juss [J]
      6. The Anti-Tumor Effect Of The Extracts Of Patrinia Villosa Juss


      Peach kernel extract
      (emen Persicae)

      1. Analgesic Treatment With Kampo Prescription
      2. Emerging Role Of Chinese Herbal Medicines In The Treatment Of Pancreatic Fibrosis
      3. Polyphenols Contents And Antioxidant Capacity Of 68 Chinese Herbals Suitable For Medical Or Food Uses
      4. Traditional Chinese Functional Foods


      pectolinarin
      (Linaria vulgaris Hill subsp.)

      1. Chemical Constituents Of Distictella Elongata (Vahl) Urb.(Bignoniaceae)
      2. Meta-Analysis Of Flavonoids With Antiviral Potential Against Coronavirus
      3. Potential Of Plant Bioactive Compounds As Sars-Cov-2 Main Protease (Mpro) And Spike (S) Glycoprotein Inhibitors: A Molecular Docking Study
      4. Sars-Cov-2: An Update On Potential Antivirals In Light Of Sars-Cov Antiviral Drug Discoveries

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      Pelargonium sidoides
      (Pelargonium peltatum (L.) Ait.)

      1. Biological Studies Concerning The Antioxidant And Antimicrobial Activities Of Pelargonium Species Cultivated In Egypt (Family-Geraniaceae)
      2. The Phytochemical Composition, Biological Effects And Biotechnological Approaches To The Production Of High-Value Essential Oil From Geranium

      ” alt=”” width=”396″ height=”307″ data-src=”https://theinterstellarplan.com/wp-content/uploads/2020/07/Pentadienoylpiperidine.jpg” />
      Pentadienoylpiperidine
      (pepper extract)

      1. (Alkylamino) Piperidine Bis (Heteroaryl) Piperizine Analogs Are Potent, Broad-Spectrum Nonnucleoside Reverse Transcriptase Inhibitors Of Drug-Resistant Isolates Of …
      2. Design, Synthesis And Trypanocidal Evaluation Of Novel 1, 2, 4-Triazoles-3-Thiones Derived From Natural Piperine
      3. Discovery And Sar Study Of Piperidine-Based Derivatives As Novel Influenza virus Inhibitors
      4. Discovery Of Spiro-Piperidine Inhibitors And Their Modulation Of The Dynamics Of The M2 Proton Channel From Influenza A virus
      5. Novel 4, 4-Disubstituted Piperidine-Based C–C Chemokine Receptor-5 Inhibitors With High Potency Against Human Immunodeficiency virus -1 And An Improved Human …
      6. Optical Dna Biosensor Based On Square-Planar Ethyl Piperidine Substituted Nickel (Ii) Salphen Complex For Dengue virus Detection
      7. Synthesis And Preliminary Antiviral Activities Of Piperidine‐Substituted Purines Against Hiv And Influenza A/H1N1 Infections

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      Phragmitescommunis Trin extract
      (Phragmites australis (Cav.) Trin. ex Steud)

      1. Antibacterial Activity Of Traditional Australian Medicinal Plants
      2. Anti-Inflammatory And Antiviral Effects Of Water-Soluble Crude Extract From Phragmites Australis In Vitro.
      3. Antiviral Chinese Medicinal Herbs Against Respiratory Syncytial virus
      4. Bacteriophages In Engineered Wetland For Domestic Wastewater Treatment
      5. Bioactive Secondary Metabolites Produced By An Endophytic Fungus Gaeumannomyces Sp. Js0464 From A Maritime Halophyte Phragmites Communis
      6. Botanical Identification Of Medicinal Roots Collected And Traded In Morocco And Comparison To The Existing Literature
      7. Functional Role Of Bacteria From Invasive Phragmites Australis In Promotion Of Host Growth

      Phyllanthus orbicularis
      (Phyllanthus orbicularis Kunth)

      1. 14 Antiviral Activities Of Phyllanthus Orbicularis, An Endemic Cuban Species
      2. Bioactivity‐Guided Fractionation Of Phyllanthus Orbicularis And Identification Of The Principal Anti Hsv‐2 Compounds
      3. Evaluation Of The Antiviral Activity Of An Aqueous Extract From Phyllanthus Orbicularis
      4. In Vitro Antiviral Activity Of Phyllanthus Orbicularis Extracts Against Herpes Simplex virus Type 1
      5. Insights Into The Phytochemistry Of The Cuban Endemic Medicinal Plant Phyllanthus Orbicularis: Fideloside, A Novel Bioactive 8-C-Glycosyl 2, 3-Dihydroflavonol
      6. Preliminary Evaluation Of The Antiviral Activity Of The Aqueous Extract Of Phyllanthus Orbicularis Vs Hiv-1 Infection
      7. Protective Effect Of A Phyllanthus Orbicularis Aqueous Extract Against Uvb Light In Human Cells


      Pinusolidic acid
      (Vanillin and Malonic acid)

      1. Essential Oil And Important Activities Of Thuja Orientalis And Thuja Occidentalis
      2. Facile Synthesis Of Novel Vanillin Derivatives Incorporating A Bis (2-Hydroxyethyl) Dithhioacetal Moiety As Antiviral Agents
      3. Specific Plant Terpenoids And Lignoids Possess Potent Antiviral Activities Against Severe Acute Respiratory Syndrome Coronavirus

      ” alt=”” width=”248″ height=”401″ data-src=”https://theinterstellarplan.com/wp-content/uploads/2020/07/Piperettine.jpg” />
      Piperettine
      (pepper extract)

      1. A Review On Diversified Use Of The King Of Spices: Piper Nigrum (Black Pepper)
      2. Piperine: A Comprehensive Review Of Methods Of Isolation, Purification And Biological Properties
      3. Postharvest Processing And Benefits Of Black Pepper, Coriander, Cinnamon, Fenugreek, And Turmeric Spices

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      Pipericide
      (pepper extract)

      1. A Review On Diversified Use Of The King Of Spices: Piper Nigrum (Black Pepper)
      2. Indian Traditional Ayurvedic Treatment Regime For Novel Coronavirus , Covid-19
      3. Plant Biodiversity As A Resource For Natural Products For Insect Pest Management
      4. Prevention And Treatment Of Different Health Problems By Common Peoples Diet (Haleem)
      5. Review On Kukkiladhi Choornam Used In Traditional Medicine And Research Activities
      6. World Journal Of Pharmaceutical And Life Sciences Wjpls

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      Piperine
      (pepper extract)

      1. Antibacterial Activity Of Black Pepper (Piper Nigrum Linn.) With Special Reference To Its Mode Of Action On Bacteria
      2. Antiradical Properties Of Essential Oils And Extracts From Coriander, Cardamom, White, Red, And Black Peppers
      3. Application Of Plant Extracts As Feed Additives In Poultry Nutrition
      4. Bioassay-Guided Fractionation Of Wound Healing Active Compounds From Piper Nigrum L. Berries Extract In Malaysia
      5. Effectiveness Of Herbal Extract (Piper Retrofractum, Curcuma Aeruginosa, And Curcuma Zanthorrhiza) As Immunomodulator In Non-Specific Immunity System Of Tiger …
      6. Opuntiol: An Active Principle Of Opuntia Elatior As An Eco-Friendly Inhibitor Of Corrosion Of Mild Steel In Acid Medium
      7. Piperine: A Comprehensive Review Of Methods Of Isolation, Purification And Biological Properties
      8. Recent Trends In The Utilization Of Medicinal Plants As Growth Promoters In Poultry Nutrition–A Review
      9. Spices-An Imperative Melange-Back To The Roots
      10. The Antimicrobial Effects Of Local Spices: Onions (Allium Cepa, Garlic (Allium Sativum), Ginger (Zingiber Officinale), And Pepper (Piper Guineense) On Selected …
      11. molecular docking study of the structural disruption of the viral 3CL-protease of COVID19 induced by binding of capsaicin, piperine and curcumin
      12. Immunomodulatory and antitumor activity of Piper longum Linn. and piperine
      13. Piperine inhibits cytokine production by human peripheral blood mononuclear cells

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      Piperolein b
      (pepper extract)

      1. A Review On Diversified Use Of The King Of Spices: Piper Nigrum (Black Pepper)
      2. Piperine: A Comprehensive Review Of Methods Of Isolation, Purification And Biological Properties


      Poria Cocos Extract
      ((Poria cocos(Schw.)Wolf.))

      1. A Standardized Composition From Extracts Of Myristica Fragrans, Astragalus Membranaceus, And Poria Cocos Protects Liver From Acute Ethanol Insult
      2. Diversity Of Wild Mushrooms And Its Medicinal Uses
      3. Mushrooms As A Functional Food Mediator In Preventing And Ameliorating Diabetes
      4. Pharmacokinetic Behaviour Of Clinically Important Tcm Prescriptions
      5. The Effect Of Poria Cocos Extract To Inhibit Enterovirus Replication


      protocatechuic acid
      (Stenoloma chusanum(L.)Ching leaves)

      1. A Review On Protocatechuic Acid And Its Pharmacological Potential
      2. Biomarkers Of Foods And Nutraceuticals: Applications In Efficacy, Safety, And Toxicity
      3. In Vitro Anti-Influenza virus Activity Of Synthetic Humate Analogues Derived From Protocatechuic Acid
      4. Inhibitory Effect Of Lamivudine Combined With Protocatechuic Acid On Duck Hepatitis B virus In Vitro.
      5. Pharmacodynamic Study Of Lamivudine Combined With Protocatechuic Acid Against Hepatitis B virus In Vitro [J]
      6. Pro-Apoptosis Effects Of Protocatechuic Acid In The Early Stage Of Infectious Bursal Disease virus Infection
      7. Protocatechuic Acid (Pca) Induced A Better Antiviral Effect By Immune Enhancement In Spf Chickens
      8. Protocatechuic Acid Inhibits Hepatitis B virus Replication By Activating Erk1/2 Pathway And Down-Regulating Hnf4Α And Hnf1Α In Vitro
      9. Protocatechuic Acid, A New Active Substance Against The Challenge Of Avian Infectious Bursal Disease virus
      10. Protocatechuic Acid, A Novel Active Substance Against Avian Influenza virus H9N2 Infection
      11. Prototype Foamy virus Intasome Aggregation Is Mediated By Outer Protein Domains And Prevented By Protocatechuic Acid

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      protopine
      (Corydalis yanhusuo W.T.Wang)

      1. Active Phytochemicals From Chinese Herbs As Therapeutic Agents For The Heart
      2. Advances In Phytochemical And Modern Pharmacological Research Of Rhizoma Corydalis
      3. Analysis Of Chemical Constituents In An Herbal Formula Jitong Ning Tablet
      4. Application Of Ultrafiltration Membrane Techology In The Preparation Of Traditional Chinese Medicine [J]
      5. Comparative Analysis Of The Chemical Profile Of Wild And Cultivated Populations Of Corydalis Saxicola By High‐Performance Liquid Chromatography
      6. Determination Of Selected Isoquinoline Alkaloids From Mahonia Aquifolia; Meconopsis Cambrica; Corydalis Lutea; Dicentra Spectabilis; Fumaria Officinalis; …
      7. Holistic Psychopharmacology Of Fumaria Indica (Fumitory)
      8. Identification Of Isoquinoline Alkaloids From Berberis Microphylla By Hplc Esi-Ms/Ms
      9. In Vivo Disease Control Efficacy Of Isoquinoline Alkaloids Isolated From Corydalis Ternata Against Wheat Leaf Rust And Pepper Anthracnose
      10. Protopine Inhibits Heterotypic Celladhesion In Mda-Mb-231 Cells Through Down-Regulation Of Multi-Adhesive Factors
      11. Quality Evaluation Of Corydalis Yanhusuo By High-Performance Liquid Chromatography Fingerprinting Coupled With Multicomponent Quantitative Analysis
      12. Screening Of Bioactive Components From Traditional Chinese Medicine By Immobilized Β2 Adrenergic Receptor Coupled With High Performance Liquid Chromatography …


      Quercetin
      (sophora japonica extract)

      1. Anti-Inflammatory, Antiviral And Quantitative Study Of Quercetin-3-O-Β-D-Glucuronide In Polygonum Perfoliatum L.
      2. Antiviral Activities Of Quercetin And Isoquercitrin Against Human Herpesvirus es
      3. Antiviral Activity Of Baicalein And Quercetin Against The Japanese Encephalitis virus
      4. Antiviral Activity Of Quercetin 7-Rhamnoside Against Porcine Epidemic Diarrhea virus
      5. Antiviral Activity Of Quercetin-3-Β-Od-Glucoside Against Zika virus Infection
      6. Antiviral Effects Of Quercetin And Related Compounds
      7. Effectivity Of Quercetin As Antiviral To Dengue virus -2 Strain New Guinea C In Huh 7-It 1 Cell Line
      8. Ethanolic Extract Of Sophora Japonica Flower Buds Alleviates Cognitive Deficits Induced By Scopolamine In Mice
      9. Evaluation Of Antiviral Activities Of Houttuynia Cordata Thunb. Extract, Quercetin, Quercetrin And Cinanserin On Murine Coronavirus And Dengue virus Infection
      10. Evaluation Of The Antiviral Activities Of Bacharis Dracunculifolia And Quercetin On Equid Herpesvirus 1 In A Murine Model
      11. In Silico Prediction Of Phosphorylation Of Ns3 As An Essential Mechanism For Dengue virus Replication And The Antiviral Activity Of Quercetin
      12. In Vitro Antiviral Mechanisms Of Eugeniin And Quercetin Against Varicella-Zoster virus
      13. In Vitro Assessment Of The Antiviral Potential Of Trans-Cinnamic Acid, Quercetin And Morin Against Equid Herpesvirus 1
      14. Male Reprotoxicity Associated With Sophora Japonica Treatment: Evaluation Of Cellular And Molecular Events In Vitro
      15. Mechanism Of Antiviral Action Of Quercetin Against Cardiovirus Infection In Mice
      16. Quercetin As An Antiviral Agent Inhibits Influenza A virus (Iav) Entry
      17. Quercetin Potentiates Tnf-Induced Antiviral Activity
      18. Synthesis And Antiviral Activity Of Quercetin Brominated Derivatives
      19. Synthesizing Microcarriers As A Platform For The Pharmaceutical Delivery Of Quercetin For Antiviral Applications

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      Quercetin-3-b-galactoside
      (St. John’s wort)

      1. A Comprehensive Review On The Effect Of Plant Metabolites On Coronavirus es: Focusing On Their Molecular Docking Score And Ic50 Values
      2. Anti-Inflammatory Constituents In Hypericum Species And Unveiling The Underlying Mechanism In Lps-Stimulated Mouse Macrophages And H1N1 Influenza virus …
      3. Anti-Influenza A virus Effect Of Hypericum Perforatum L. Extract
      4. Antiviral Activity Against Infectious Bronchitis virus And Bioactive Components Of Hypericum Perforatum L.
      5. Antiviral Activity Of The Infusion (Shs‐174) From Flowers Of Sambucus Nigra L., Aerial Parts Of Hypericum Perforatum L., And Roots Of Saponaria Officinalis L. Against …
      6. Antiviral Effect Of Two Tintures Obtained Of Hypericum Cultivated In Cuba.
      7. Antiviral In Vitro Activity Of Hypericum Perforatum L. Extract On The Human Cytomegalovirus (Hcmv)
      8. Effect Of Anti-Influenza virus H3N2 Of Hypericum Japonicum In Vivo
      9. Effect Study Of Cthanol Extract Of Hypericum Perforatum On Influenza virus
      10. Effect Study Of Ethanol Extract Of Hypericum Perforatum On Influenza virus [J]
      11. Evaluation Of The Cytotoxic Effect And Antibacterial, Antifungal, And Antiviral Activities Of Hypericum Triquetrifolium Turra Essential Oils From Tunisia
      12. Evidence And Characterization Of A virus Of St John’S Wort (Hypericum Perfora Tum L.)
      13. Extracts And Constituents Of Hypericum Perforatum Inhibit The Binding Of Various Ligands To Recombinant Receptors Expressed With The Semliki Forest virus System
      14. Filicinic Acid Based Meroterpenoids With Anti-Epstein–Barr virus Activities From Hypericum Japonicum
      15. Herpes virus Inhibitory Substances From Hypericum Connatum Lam., A Plant Used In Southern Brazil To Treat Oral Lesions
      16. Hypericum Perforatum Extract Therapy For Chickens Experimentally Infected With Infectious Bursal Disease virus And Its Influence On Immunity
      17. Hypericum Perforatum Inhibits The Binding Of Μ-And Κ-Opioid Receptor Expressed With The Semliki Forest virus System
      18. Identification Of Light-Independent Inhibition Of Human Immunodeficiency virus -1 Infection Through Bioguided Fractionation Of Hypericum Perforatum
      19. In Vitro And In Vivo viral Inhibitory Activity Of Hypericum Species Against Newcastle Disease virus
      20. In Vitro Anti-Hepatitis B virus Effect Of Hypericum Perforatum L.
      21. Influence Of Hypericum Perforatum Extract On Ifn-Γ, Tnf-Α Of Lung Tissue Of Mice Infected With Influenza A virus [J]
      22. Influence Of Hypericum Perforatum Extract On Piglet Infected With Porcine Respiratory And Reproductive Syndrome virus
      23. Inhibition Of Hypericum Perforatum Extract On Influenza A virus .
      24. Investigation Of Some Hypericum Species Native To Southern Of Brazil For Antiviral Activity
      25. Isolation And Anticancer, Anthelminthic, And Antiviral (Hiv) Activity Of Acylphloroglucinols, And Regioselective Synthesis Of Empetrifranzinans From Hypericum …
      26. Study On Effect Of Hypericum Perforatum On Pharmacokinetics Of Zedoary Turmeric Oil In Compound Antiviral Preparation
      27. The Evaluation Of The Cytotoxic Effect And The Antibacterial, Antifungal, And Antiviral Activities Of Hypericum Triquetrifolium Turra Essential Oils From Tunisia 2
      28. The Immuno-Regulatory Impact Of Orally-Administered Hypericum Perforatum Extract On Balb/C Mice Inoculated With H1N1 Influenza A virus
      29. Therapeutic Efficacy Of Hypericum Perforatum L. Extract For Mice Infected With An Influenza A virus
      30. Two New Flavones From Hypericum Chinense And Their Anti-Tobacco Mosaic virus Activity

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      quercetin-3,7-O-α-l-dirhamnoside （Quercitrin）
      (Sabina pingii var. wilsonii)

      1. In Vitro And In Silico Study To Evaluate The Effectiveness Of Quercitrin As Antiviral Drug To Dengue virus
      2. Human adenovirus (HAdV)-36 is one of the viruses that are known to cause infectobesity in humans. Unlike extensive research on preventing obesity and developing anti-obesity drugs, little research has been conducted specifically on the prevention and treatment of infectobesity. Therefore, this study aimed to evaluate the effects of phytochemicals from D. racemosum on the replication of HAdV-36. A549 cells infected with HAdV-36 were treated with an ethyl acetate fraction of a D. racemosum leaf extract (DRE), and the virus titer was calculated based on the hemagglutination (HA) titer. The results showed a concentration-dependent inhibitory effect of DRE treatment on HA titers. DRE treatment was also found to inhibit the cytopathic effects of the virus and the expression of viral genes. Quercitrin was identified as the constituent of DRE exerting an inhibitory effect on HAdV-36 replication. This study shows that DRE can be used as a candidate substance for the development of treatment for HAdV-36 infections. In addition, this study provides a basis to further investigate DRE for the development of anti-infectobesity medication.


      quinic acid
      (Cinchona bark)

      1. A New Caffeoly Quinic Acid From Aster Scaber And Its Inhibitory Activity Against Human Immunodeficiency virus -1 (Hiv-1) Integrase
      2. Anti-Hepatitis B virus Activity Of Chlorogenic Acid, Quinic Acid And Caffeic Acid In Vivo And In Vitro
      3. Biological And Anticancer Activity Of Selected Natural Products
      4. Blossoming Treasures Of Biodiversity: 19. Chinese Star Anise-Defence Against A Potentially Catastrophic Global Killer Flu virus
      5. Case Study: Oseltamivir: An Orally Bioavailable Ester Prodrug Of Oseltamivir Carboxylate
      6. Dissociation Constant Of Quinic Acid And Association Constants Of Some Quinates In Aqueous And In Alcoholic− Aqueous Mixed Solvents
      7. Formulation And Evaluation Of Oral Suspension Of Oseltamivir Phosphate Using Different Vehicle
      8. Pharmacology Of Natural Radioprotectors
      9. Quinic Acid Derivatives Inhibit Dengue virus Replication In Vitro
      10. Reactive Extraction Of Cyclic Polyhydroxy Carboxylic Acid Using Trioctylamine (Toa) In Different Diluents
      11. Shikimic Acid: A Highly Prospective Molecule In Pharmaceutical Industry
      12. Star Role For Bacteria In Controlling Flu Pandemic?
      13. Uhplc-Esi-Ms/Ms Analyses For Quantification Of Phenolic Compounds Of Nepeta Nuda Subsp. Lydiae


      Radix Codonopsis extract
      (Radix Codonopsis root)

      1. Antiviral Herbs-Present And Future
      2. Immuno-Enhancement Effects Of Shenqi Fuzheng Injection On Cyclophosphamide-Induced Immunosuppression In Balb/C Mice
      3. Prospects Of Codonopsis Pilosula Polysaccharides: Structural Features And Bioactivities Diversity
      4. Radix Bupleuri: A Review Of Traditional Uses, Botany, Phytochemistry, Pharmacology, And Toxicology
      5. Ultrastructural Observation On Pulmonary Fibrosis In E9 Rats Treated With Compound Carapax Trionycis Formula

      Radix Glehniae extract
      (CoasiaI GIehnia Root Extract)

      1. A Case Of Intoxication Caused By Aciclovir Overinfusion And Cured By Chinese Medicine
      2. A Retrospective Study On Clinical Features Of And Treatment Methods For 77 Severe Cases Of Sars
      3. Combating Covid-19 With Integrated Traditional Chinese And Western Medicine In China
      4. Decursinol Angelate Isolated From Angelica Gigantis Radix Potentiates Pentobarbital-Induced Sleeping Behaviors Via Gabaa-Ergic Systems.
      5. Differentiation Of Furanocoumarin Isomers With Ratio Of Relative Abundance Of Characteristic Fragment Ions And Application In Angelicae Dahuricae Radix
      6. Effects Of Isoimperatorin On Proliferation And Apoptosis Of Human Gastric Carcinoma Cells
      7. Ethanol Extract Of A Korean Medicinal Prescription (Ssy) Including Rehmanniae Radix Preparata Promote Hair Growth In An Alopecia Animal Model
      8. Identification Of Urinary Metabolites Of Imperatorin With A Single Run On An Lc/Triple Tof System Based On Multiple Mass Defect Filter Data Acquisition And Multiple Data …
      9. Isolation Of Lithospermi Radix And Development Of Simultaneous Analytical Method
      10. Isolation, Purification, Structural Analysis And Biological Activities Of Water-Soluble Polysaccharide From Glehniae Radix
      11. Lipid Raft Biomaterial As A Mass Screening Affinity Tool For Rapid Identification Of Potential Antitumor Chinese Herbal Medicine
      12. Optimizing Study For The Technics Of Extracting Polysaccharide From The Gratelou Piat Uruturu Yamada [J]
      13. Progress In Study Of Oxidative Stress And Kidney-Tonifying Chinese Herbs In Parkinson’S Disease
      14. Psoralen, A Mechanism-Based Inactivator Of Cyp2B6
      15. Stereoselective Synthesis And Biological Evaluation Of 2′-Β-Substituted-Fluoroneplanocina Analogues As Potential Antiviral And Anticancer Agents
      16. Synthesis And Antiviral Activity Of 2′, 5′, 5′-Trifluoro-3′-Hydroxy-Apiosyl Nucleoside Phosphonic Acid Analogues
      17. The Pharmacokinetics Of Psoralen In Compound Recipe And Hispid Fig Root In Rats [J]
      18. The Screening Toolbox Of Bioactive Substances From Natural Products: A Review
      19. Therapeutic Effect Of Liyan Baidu Decoction Combined With Oxygen Spray On Radioactive Stomatitis In Patients With Nasopharyngeal Carcinoma
      20. Two Traditional Chinese Medicines Curcumae Radix And Curcumae Rhizoma: An Ethnopharmacology, Phytochemistry, And Pharmacology Review
      21. Whether Herbal Medicines Play An Important Role In The Covid-19 Therapeutics And Boosting Immune As One Of The Preventive Solutions: A Science Opinion


      Radix　Platycodonis extract

      (Platycodon grandiflorum（Jacq ） A DC root)

      1. Chemical Composition And Pharmacology Research Progress Of Shenlingbaizhu Powder
      2. Correlation Study Between Antioxidant Activity And Lowering Blood Glucose Of Momordica Polysaccharide [J]
      3. Determination Of Polysaccharide Content And Molar Mass Distribution Of Isatis Indigotica Fortune Roots Planted In Daqing [J]
      4. Health Promotion In Relation To Respiratory viral Infections
      5. Study Of The Distribution Patterns Of The Constituent Herbs In Classical Chinese Medicine Prescriptions Treating Respiratory Disease By Data Mining Methods
      6. The Pharmacological Effects And Health Benefits Of Platycodon Grandiflorus—A Medicine Food Homology Species
      7. Utilization Of Chinese Medicine For Respiratory Discomforts By Patients With A Medical History Of Tuberculosis In Taiwan

      Radix Scrophulariae Extract
      (Radix Scrophulariae root)

      1. Effects Of Twenty-Five Traditional Antipyretic And Antidote Medicine Extracts Against Helicobacter Pylori From Swine In Vitro
      2. Fragmentation Study Of Iridoid Glycosides And Phenylpropanoid Glycosides In Radix Scrophulariae By Rapid Resolution Liquid Chromatography With Diode‐Array …
      3. Research On The Anti-Inflammation And Anti-Atherosclerosis Of Extracts From Radix Scrophulariae [J]
      4. Synergistic Nourishing ‘Yin’Effect Of Iridoid And Phenylpropanoid Glycosides From Radix Scrophulariae In Vivo And In Vitro
      5. Treatment Of Human Influenza A (H5N1) Infection With Ching-Wen-Bai-Du-Yin

      Reserpine
      (Rauvolfia verticillata (Lour.) Baill.)

      1. Biotechnological Interventions For Production Of Therapeutic Secondary Metabolites Using Hairy Root Cultures Of Medicinal Plants
      2. Investication On The Pharmacoprinciples Of A Pergularia Daemia (Forssk) Chiov
      3. Isolation, Chemical Profile And Antimalarial Activities Of Bioactive Compounds From Rauvolfia Caffra Sond
      4. Kandungan Reserpin\Ud Kultur Kalus Pule Pandak (Rauvolfia Verticillata (Lour.) Baillon)\Ud Setelah Dielisitasi Dengan Cendawan Pythium …
      5. New Perspectives On How To Discover Drugs From Herbal Medicines: Cam’S Outstanding Contribution To Modern Therapeutics
      6. Tcm-Based New Drug Discovery And Development In China

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      Resveratrol
      (Polygonum cuspidatum extract)

      1. 3, 4′, 5-Trihydroxy-Trans-Stilbene (Resveratrol) Inhibits Human Cytomegalovirus Replication And virus -Induced Cellular Signaling
      2. An Antioxidant Resveratrol Significantly Enhanced Replication Of Hepatitis C virus
      3. Antiviral Activities Of Resveratrol Against Rotavirus In Vitro And In Vivo
      4. Antiviral Activity Of Resveratrol
      5. Antiviral Activity Of Resveratrol Against Human And Animal virus es
      6. Antiviral Effect Of Resveratrol In Ducklings Infected With Virulent Duck Enteritis virus
      7. Antiviral Effect Of Resveratrol In Piglets Infected With Virulent Pseudorabies virus
      8. Antiviral Properties Of Resveratrol Against Pseudorabies virus Are Associated With The Inhibition Of Iκb Kinase Activation
      9. Chemopreventive Effect Of Resveratrol, Sesamol, Sesame Oil And Sunflower Oil In The Epstein–Barr virus Early Antigen Activation Assay And The Mouse Skin Two-Stage …
      10. Comparative Inhibitory Activity Of The Stilbenes Resveratrol And Oxyresveratrol On African Swine Fever virus Replication
      11. Development And Application Of Real-Time Fluorescence Quantitative Pcr For Detecting The Antiviral Activity Of Resveratrol Against Duck Plague virus In Vitro.
      12. Does Resveratrol Exhibit Antiviral Properties Against Cytomegalovirus Replication?
      13. Effect Of Resveratrol On Herpes Simplex virus Vaginal Infection In The Mouse
      14. Effect Of Topically Applied Resveratrol On Cutaneous Herpes Simplex virus Infections In Hairless Mice
      15. Identification Of A Resveratrol Tetramer As A Potent Inhibitor Of Hepatitis C virus Helicase
      16. In Vitro Antiviral Effects And 3D Qsar Study Of Resveratrol Derivatives As Potent Inhibitors Of Influenza H1N1 Neuraminidase
      17. Inhibition Of Influenza A virus Replication By Resveratrol
      18. Inhibitory Effect Of Resveratrol Against Duck Enteritis virus In Vitro
      19. Inhibitory Effects Of Resveratrol On The Epstein-Barr virus Lytic Cycle
      20. Resveratrol Exhibits A Strong Cytotoxic Activity In Cultured Cells And Has An Antiviral Action Against Polyomavirus : Potential Clinical Use
      21. Resveratrol Helps Recovery From Fatty Liver And Protects Against Hepatocellular Carcinoma Induced By Hepatitis B virus X Protein In A Mouse Model
      22. Resveratrol Inhibition Of Herpes Simplex virus Replication
      23. Resveratrol Inhibition Of Varicella-Zoster virus Replication In Vitro
      24. Resveratrol Inhibits Epstein Barr virus Lytic Cycle In Burkitt’S Lymphoma Cells By Affecting Multiple Molecular Targets
      25. Resveratrol Inhibits Proliferation And Survival Of Epstein Barr virus –Infected Burkitt’S Lymphoma Cells Depending On viral Latency Program
      26. Resveratrol Inhibits Respiratory Syncytial virus -Induced Il-6 Production, Decreases viral Replication, And Downregulates Trif Expression In Airway Epithelial …
      27. Resveratrol Inhibits The Trif-Dependent Pathway By Upregulating Sterile Alpha And Armadillo Motif Protein, Contributing To Anti-Inflammatory Effects After Respiratory …
      28. Resveratrol Prevents Hepatic Steatosis Induced By Hepatitis C virus Core Protein
      29. Resveratrol Suppresses Nuclear Factor-Κb In Herpes Simplex virus Infected Cells
      30. Resveratrol Trimer Enhances Gene Delivery To Hematopoietic Stem Cells By Reducing Antiviral Restriction At Endosomes
      31. Resveratrol-Mediated Gamma Interferon Reduction Prevents Airway Inflammation And Airway Hyperresponsiveness In Respiratory Syncytial virus -Infected …
      32. Study On Mechanism Of Antiviral Effect Of Resveratrol Against Coxsackie virus In Vitro
      33. The Effects Of Resveratrol On Antibacterial And Antiviral Properties

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      Retrofractamide A
      (black pepper)

      1. Overview Of Chemical Constituents And Pharmacological Activities Of Piper Longum Linn.
      2. Plant Biodiversity As A Resource For Natural Products For Insect Pest Management
      3. The Phosphine-Catalyzed Alkyne To 1, 3-Diene Isomerization Reaction

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      Rhamnetin
      (Syzygium aromaticum (L.)Merr.et Perry)

      1. Antimicrobial Efficacy Of Five Essential Oils Against Oral Pathogens: An In Vitro Study
      2. Effects Of The Syzygium Aromaticum L. Extract On Antioxidation And Inhibition Of Matrix Metalloproteinase In Human Dermal Fibroblast
      3. Enhancing The Flavour Of Oil By Infusion Of Different Herbs-Review
      4. Eugenia Caryophyllata Thunberg (Family Myrtaceae): A Review
      5. Hepatoprotective Effect Of Methanolic Extract Of Syzygium Aromaticum Against Hydralazine Induced Toxicity: An In Vitro Study
      6. In Silico Analysis Of Phytochemicals From Clove Against Bronchitis
        Inhibitory Spectra Of Isolated Tannin-Rich Fraction And Assessment Of Compounds Using Chromatographic Techniques.
      7. New Flavonol Glucuronides From The Flower Buds Of Syzygium Aromaticum (Clove)
      8. Other Health Benefits Of African Medicinal Spices And Vegetables
      9. Quality Assessment Of Syzygium Aromaticum: A Pharmacognostic And Phytochemical Approach
      10. Recent Trends In Indian Traditional Herbs Syzygium Aromaticum And Its Health Benefits
      11. Syzygium Aromaticum
      12. Syzygium Aromaticum L.(Myrtaceae): Traditional Uses, Bioactive Chemical Constituents, Pharmacological And Toxicological Activities
      13. Therapeutic And Medicinal Uses Of Lavanga-A Review
      14. It was found that flavonol-type compounds with 3′,4′-dihydroxy substitution, such as quercetin, physetin, and rhamnetin have the highest viral DNA binding inhibitory effect
      15. Rhamnetin, by increasing the expression of its target gene, it may increase the expression of RIPK3 (Figure 1). Thereby, it may: (1) augment chemokine levels; (2) trigger neuroinflammation; (3) stall neuroinvasive West Nile virus replication; (4) promote clearance of neuroinvasive West Nile virus (WNV); and (5) strengthen antiviral immunity against RNA viruses.

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      Rhizoma Atractylodis Macrocephalae extract
      (Rhizoma Atractylodis Macrocephalae root)

      1. A Review And Comment On The Current Situation Of 2019 Novel Coronavirus Prevention By Traditional Chinese Medicine
      2. Can Chinese Medicine Be Used For Prevention Of Corona virus Disease 2019 (Covid-19)? A Review Of Historical Classics, Research Evidence And Current …
      3. Chemical Composition And Pharmacology Research Progress Of Shenlingbaizhu Powder
      4. Chinese Herbal Medicine For Sars And Sars-Cov-2 Treatment And Prevention, Encouraging Using Herbal Medicine For Covid-19 Outbreak
      5. Diagnosis, Treatment, And Prevention Of 2019 Novel Coronavirus Infection In Children: Experts’ Consensus Statement
      6. Effect Of Fuzheng Huayu Formula And Its Actions Against Liver Fibrosis
      7. Efficacy Of Traditional Chinese Herbal Medicine In The Treatment Of Gastrointestinal Polyps And Chronic Gastritis: A Case Report
      8. Enhancement Action Of Yupingfeng Powder (Jiawei)(Radix Astragali Seu Hedysari, Rhizoma Atractylodis Macrocephalae, Etc.) On Immune Function Of Mice
      9. Medicinal Herbs For Hepatitis C virus Infection
      10. Protective Effect Of A Polysaccharide From Rhizoma Atractylodis Macrocephalae On Acute Liver Injury In Mice
      11. Traditional Chinese Medicine For Human Papillomavirus (Hpv) Infections: A Systematic Review
      12. Antiviral activities of atractylon from Atractylodis Rhizoma

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      Rhizoma Pinelliae extract
      (Pinellia ternata (Thunb.) Breit )

      1. Comparative Research Of The Curative Effects Of Pinelliae Rhizoma And Pinelliae Rhizoma Praeparatum Cum Alumine On Ovalbumin-Induced Allergic Asthma In …
      2. Comprehensive Quality Evaluation Of Rhizoma Pinelliae From Different Origin By Clustering Analysis Method
      3. Determination For Free Total Organic Acids In Pinellia Ternate By Direct Potential Titration [J]
      4. Experimental Study On Acute Toxicity And Irritation Of Extracts From Raw Kansui And Vinegared Kansui [J]
      5. Herbal Therapies For Epilepsy: Chemistry, Biology And Potential Applications Of Selected Plants And Compounds.
      6. Plant Species Forbidden In Health Food And Their Toxic Constituents, Toxicology And Detoxification
      7. Purification And Characterization Of A Novel Plant Lectin From Pinellia Ternata With Antineoplastic Activity
      8. Radix Bupleuri: A Review Of Traditional Uses, Botany, Phytochemistry, Pharmacology, And Toxicology
      9. Rapid Method For Simultaneous Determination Of 11 Chemical Constituents In The Traditional Chinese Medicinal Prescription Wu-Ji-San By Reverse Phase High …
      10. Simultaneous Determination Of Nine Nucleosides In The Rhizome Of Pinellia Ternata From Different Origins And Its Counterfeit By Hplc∗
      11. Study On Anti-Tumor Mechanism Of Minor Bupleurum Decoction
      12. The Cyclodipeptides Compounds From Pinellia Ternate (Thunb.) Breit
      13. The Ethnobotanical, Phytochemical And Pharmacological Profile Of The Genus Pinellia
      14. Chinese herbal medicine for coronavirus disease 2019: A systematic review and meta-analysis
      15. Traditional Chinese medicine compound preparation for treating viral hepatitis
      16. Antiviral herbs-present and future

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      rhoifolin
      (Turpinia arguya Seem leaves)

      1. A Fluorescence Resonance Energy Transfer-Based Fluorometer Assay For Screening Anti-Coxsackievirus B3 Compounds
      2. Ameliorative Effects Of Rhoifolin In Scopolamine-Induced Amnesic Zebrafish (Danio Rerio) Model
      3. An Efficient Method For The Preparative Isolation And Purification Of Flavonoid Glycosides And Caffeoylquinic Acid Derivatives From Leaves Of Lonicera Japonica Thunb …
      4. An Overview Of Citrus Aurantium Used In Treatment Of Various Diseases
      5. Antioxidant Activity Of Flavonoids From Leaves Of Jatropha Curcas
      6. Antiviral Activity Of Natural Occurring Flavonoids In Vitro
      7. Comparative Antiarrhythmic And Anti‐Ischaemic Activity Of Some Flavones In The Guinea‐Pig And Rat
      8. Covid-19 And Flavonoids: In Silico Molecular Dynamics Docking To The Active Catalytic Site Of Sars-Cov And Sars-Cov-2 Main Protease
      9. Distribution Of Flavonoids And Furocoumarins In Juices From Cultivars Of Citrus Bergamia Risso
      10. Flavonoids In Grapefruit And Commercial Grapefruit Juices: Concentration, Distribution, And Potential Health Benefi Ts
      11. Inhibition Of African Swine Fever virus Infection By Genkwanin
      12. Inhibition Of Sars-Cov 3Cl Protease By Flavonoids
      13. Inhibitory Activity Of Flavonoids And Tannins Against Hiv-1 Protease
      14. Meta-Analysis Of Flavonoids With Antiviral Potential Against Coronavirus
      15. Natural Compounds As Potential Inhibitors Of Novel Coronavirus (Covid-19) Main Protease: An In Silico Study
      16. Optimization Of A Liquid Chromatography Method Based On Simultaneous Electrospray Ionization Mass Spectrometric And Ultraviolet Photodiode Array Detection For …
      17. Phenolic Constituents From The Flower Buds Of Lonicera Japonica And Their 5-Lipoxygenase Inhibitory Activities
      18. Potential Of Plant Bioactive Compounds As Sars-Cov-2 Main Protease (Mpro) And Spike (S) Glycoprotein Inhibitors: A Molecular Docking Study
      19. Production Of Rhoifolin And Tiliroside From Callus Cultures Of Chorisia Chodatii And Chorisia Speciosa
      20. Rhoifolin: A Review Of Sources And Biological Activities
      21. Rhoifolin; A Potent Antiproliferative Effect On Cancer Cell Lines
      22. Sars-Cov-2: An Update On Potential Antivirals In Light Of Sars-Cov Antiviral Drug Discoveries
      23. Separation Of Flavanone-7-O-Glycoside Diastereomers And Analysis In Citrus Juices By Multidimensional Liquid Chromatography Coupled With Mass Spectrometry
      24. Skrining Turunan Flavonoid Sebagai Kandidat Inhibitor Protease Nsp2 Dari virus Chikungunya Menggunakan Molecular Docking
      25. Structure Characterization Of Flavonoid O‐Diglycosides By Positive And Negative Nano‐Electrospray Ionization Ion Trap Mass Spectrometry


      Rosmarinic acid
      (rosemary extract)

      1. A Model For Involvement Of Proline During Pseudomonas‐Meaiated Stimulation Of Rosmarinic Acid Levels In Oregano Shoot Clones
      2. Anti-Atherosclerosis Activity Of Rosmarinic Acid In Human Aortic Smooth Muscle Cells
      3. Antioxidant Activity Of A Rosemary Extract And Its Constituents, Carnosic Acid, Carnosol, And Rosmarinic Acid, In Bulk Oil And Oil-In-Water Emulsion
      4. Antioxidant And Antimicrobial Activities Of Rosemary Extracts Linked To Their Polyphenol Composition
      5. Antiviral Effect Of Aqueous Extracts From Species Of The Lamiaceae Family Against Herpes Simplex virus Type 1 And Type 2 In Vitro
      6. Application Of Organic Solvent Nanofiltration For Concentration Of Antioxidant Extracts Of Rosemary (Rosmarinus Officiallis L.)
      7. Bioactivity And Potential Health Benefits Of Rosmarinic Acid
      8. Biosynthesis And Accumulation Of Rosmarinic Acid In Plant Cell Cultures
      9. Biotechnological Applications For Rosmarinic Acid Production In Plant
      10. Degradation Study Of Carnosic Acid, Carnosol, Rosmarinic Acid, And Rosemary Extract (Rosmarinus Officinalis L.) Assessed Using Hplc
      11. Effect Of Phenological Stages On Essential Oil Content, Composition And Rosmarinic Acid In Rosmarinus Officinalis L.
      12. Extractability Of Rosmarinic Acid By Using Three Different Aqueous Based Extraction Procedures
      13. Impact Of Ethanolic Lamiaceae Extracts On Herpesvirus Infectivity In Cell Culture
      14. In Vivo Analgesic And Anti-Inflammatory Activities Of Rosmarinus Officinalis Aqueous Extracts, Rosmarinic Acid And Its Acetyl Ester Derivative
      15. Investigation Of Lepechinia Graveolens For Its Antioxidant Activity And Phenolic Composition
      16. Optimization Of Rosmarinic Acid Extraction From Lemon Balm (Melissa Officinalis)
      17. Phenolic Antioxidant Compounds Produced By In Vitro. Cultures Of Rosemary (Rosmarinus Officinalis.) And Their Anti-Inflammatory Effect On Lipopolysaccharide …
      18. Prooxidant Action Of Rosmarinic Acid: Transition Metal-Dependent Generation Of Reactive Oxygen Species
      19. Prophylactic Effects Of Ellagic Acid And Rosmarinic Acid On Doxorubicin‐Induced Neurotoxicity In Rats
      20. Recovery And Purification Of Rosmarinic Acid From Rosemary Using Electrodialysis
      21. Review On Rosmarinic Acid Extraction, Fractionation And Its Anti-Diabetic Potential
      22. Rosemary (Rosmarinic Acid)
      23. Rosmarinic Acid Alleviates Neurological Symptoms In The G93A-Sod1 Transgenic Mouse Model Of Amyotrophic Lateral Sclerosis
      24. Rosmarinic Acid As Potential Anti-Inflammatory Agent
      25. Rosmarinic Acid From Beach Waste: Isolation And Hplc Quantification In Zostera Detritus From Arcachon Lagoon
      26. Rosmarinic Acid, A Photo-Protective Agent Against Uv And Other Ionizing Radiations
      27. Rosmarinus Officinalis L.: An Update Review Of Its Phytochemistry And Biological Activity
      28. Solvent Extraction And Purification Of Rosmarinic Acid From Supercritical Fluid Extraction Fractionation Waste: Economic Evaluation And Scale-Up
      29. Stability Of Rosmarinic Acid In Aqueous Extracts From Different Lamiaceae Species After In Vitro Digestion With Human Gastrointestinal Enzymes
      30. Storage Method, Drying Processes And Extraction Procedures Strongly Affect The Phenolic Fraction Of Rosemary Leaves: An Hplc/Dad/Ms Study
      31. The Effect Of Methyl Jasmonate On Production Of Antioxidant Compounds In Shoot Cultures Of Salvia Officinalis L
      32. The Effect Of Rosmarinic Acid On Immunological And Neurological Systems
      33. The Effect Of Triacontanol On Shoot Multiplication And Production Of Antioxidant Compounds In Shoot Cultures Of Salvia Officinalis L.
      34. Therapeutic And Nutraceutical Potential Of Rosmarinic Acid—Cytoprotective Properties And Pharmacokinetic Profile
      35. Therapeutic Potential Of Rosmarinic Acid: A Comprehensive Review
      36. Voltammetric Determination Of Rosmarinic Acid On Chitosan/Carbon Nanotube Composite-Modified Carbon Paste Electrode Covered With Dna


      rupestonic acid
      (Artemisia rupestris L.)

      1. 1, 2, 3-Triazole-Containing Derivatives Of Rupestonic Acid: Click-Chemical Synthesis And Antiviral Activities Against Influenza virus es
      2. Achievements In The Research Of Artemisia Rupestris L.
      3. Advances In Studies On The Rupestonic Acid Derivatives As Anti-Influenza Agents.
      4. Anti-Flu Effect Of Compound Yizhihao Granule And Its Effective Components
      5. Anti-Microbial Effects Of Different Extracts Obtained From Artemisia Rupestris Cytotoxické, Protirakovinné A Antimikrobiální Účinky Extraktů Z Artemisia Rupestris
      6. Chemical Modification Of Rupestonic Acid And Preliminarily In Vitro Antiviral Activity Against Influenza A3 And B virus es
      7. Chinese Herbal Medicine Compound Yi-Zhi-Hao Pellet Inhibits Replication Of Influenza virus Infection Through Activation Of Heme Oxygenase-1
      8. Discovery Of Multitarget-Directed Ligands Against Influenza A virus From Compound Yizhihao Through A Predictive System For Compound-Protein …
      9. Dmo-Cap Inhibits Influenza virus Replication By Activating Heme Oxygenase-1-Mediated Ifn Response
      10. Effects Of Artemisiae Rupestris Granules On Anti-Inflammatory And Immune Function In Mice [J]
      11. Pl-02 Study On The Active Compounds Of Ethnic Medicine And Rupestonic Acid Derivatives
      12. Pp-201 Synthesis And Anti-Influenza Activity Of Rupestonic Acid Derivatives
      13. Quantitative Determination Of Rupestonic Acid In Rat Plasma By High‐Performance Liquid Chromatography–Tandem Mass Spectrometry And Its Application In A …
      14. Rupestonic Acid Derivative Yzh-106 Suppresses Influenza virus Replication By Activation Of Heme Oxygenase-1-Mediated Interferon Response
      15. Structural Modification On Rupestonic Acid Leads To Highly Potent Inhibitors Against Influenza virus
      16. Structure–Activity Relationship Studies Of 1-(1′-Hydroxyalkyl) Rupestonic Acid Methyl Esters Against Influenza virus es
      17. Synthesis And Anti-Influenza Activity Of Aminoalkyl Rupestonates
      18. Synthesis Of Rupestonic Acid Amide Derivatives And Their In Vitro Activity Against Type A3 And B Flu virus And Herpes Simplex I And Ii
      19. Synthesis Of Rupestonic Acid Derivatives With Antiviral Activity
      20. Unusual Guaiane Sesquiterpenoids From Artemisia Rupestris


      Rutin
      (Ruta graveolens L.)

      1. 4Th National Congress On Medicinal Plants 12, 13 May 2015 Tehran-Iran
      2. A High-Performance Thin Layer Chromatography Determination And Quantification Of Rutin In Caralluma Nilagiriana, An Endemic Medicinal Plant
      3. A Sustainable One‐Pot, Two‐Enzyme Synthesis Of Naturally Occurring Arylalkyl Glucosides
      4. Antiartherosclerotic Effects Of Plant Flavonoids
      5. Antibacterial And Cytotoxic Activities Of Some Libyan Medicinal Plants
      6. Antilymphoma Potential Of The Ethanol Extract And Rutin Obtained Of The Leaves From Schinus Molle Linn.
      7. Application Of Eco-Friendly Bismuth Film Electrode For The Sensitive Determination Of Rutin
      8. Barrier Protective Effects Of Rutin In Lps-Induced Inflammation In Vitro And In Vivo
      9. Cardioprotective Effects Of Rutin In Rats Exposed To Pirarubicin Toxicity
      10. Comparative Analysis Of Rutin Content In Some Egyptian Plants: A Validated Rp-Hplc-Dad Approach
      11. Effect Of Rutin On virus Inactivation By Amt In Combination With Ultraviolet-A Irradiation In Platelet Concentrates
      12. Effects Of Rutin And Quercetin On Monooxygenase Activities In Experimental Influenza virus Infection
      13. Effects Of The Chronic Ingestion Of An Infusion Of Ruta Chalepensis On The Vasomotor Responses Of Rat Aortic Rings
      14. Evaluation Of Five Nematode-Antagonistic Plants Used As Green Manure To Control Xiphinema Index Thorne Et Allen On Vitis Vinifera L.
      15. High-Performance Thin-Layer Chromatographic Method For Estimation Of Rutin In Medicinal Plants
      16. In Vitro Antimicrobial Activity Of Crude Extracts Of Some Medicinal Plants From Al-Baha Region In Saudi Arabia
      17. In Vitro Antiviral Activity Of Fisetin, Rutin And Naringenin Against Dengue virus Type-2
      18. Journal Of Natural Products And Resources
      19. Melt Stabilization Of Pe With Natural Antioxidants: Comparison Of Rutin And Quercetin
      20. Methyltransferases From Ruta Graveolens L.: Molecular Biology And Biochemistry
      21. Occurrence Of Rosmarinic Acid, Chlorogenic Acid And Rutin In Marantaceae Species
      22. Penentuan Serotipe virus Dengue Dan Gambaran Manifestasi Klinis Serta Hematologi Rutin Pada Infeksi virus Dengue
      23. Preparation Of Rutin-Liposome Drug Delivery Systems And Evaluation On Their In Vitro Antioxidant Activity
      24. Prevalensi virus Hepatitis Pada Pasien Penyakit Ginjal Kronik Yang Menjalani Hemodialisis Rutin Bagian Ilmu Penyakit Dalam Rsup Prof. Dr. Rd Kandou Manado
      25. Ruta Graveolens And Its Active Constituent Rutin Protect Against Diethylnitrosamine-Induced Nephrotoxicity Through Modulation Of Oxidative Stress
      26. Ruta Graveolens And Rutin, As Its Major Compound: Investigating Their Effect On Spatial Memory And Passive Avoidance Memory In Rats
      27. Ruta Graveolens: From Traditional System Of Medicine To Modern Pharmacology: An Overview
      28. Rutin And Its Cyclodextrin Inclusion Complexes: Physico-Chemical Evaluation And In Vitro Activity On B164A5 Murine Melanoma Cell Line
      29. Sterols Bioactivity Of Ruta Graveolens L. And Murraya Paniculata L.
      30. Structure‐Activity Relationships Analysis Of Monomeric And Polymeric Polyphenols (Quercetin, Rutin And Catechin) Obtained By Various Polymerization Methods
      31. The Beneficial Role Of Rutin, A Naturally Occurring Flavonoid In Health Promotion And Disease Prevention: A Systematic Review And Update
      32. The Effect Of An Aqueous Propolis Extract, Of Rutin And Of A Rutin-Quercetin Mixture On Experimental Influenza virus Infection In Mice.
      33. The Effect Of Rutin On Antioxidant And Anti-Inflammation In Streptozotocin-Induced Diabetic Rats
      34. The Pharmacological Potential Of Rutin
      35. Virtual Screening Of Natural Inhibitors To The Predicted Hbx Protein Structure Of Hepatitis B virus Using Molecular Docking For Identification Of Potential Lead …


      saikosapoins a、 b、 c、 d
      (Bupleurum extract (Radix Stellariae))

      1. 11 Pharmacological Activity Of Saikosaponins
      2. A Systematic Review Of The Active Saikosaponins And Extracts Isolated From Radix Bupleuri And Their Applications
      3. An In-Silico Evaluation Of Different Saikosaponins For Their Potency Against Sars-Cov-2 Using Nsp15 And Fusion Spike Glycoprotein As Targets
      4. Antiviral Activity Of Seven Iridoids, Three Saikosaponins And One Phenylpropanoid Glycoside Extracted From Bupleurum Rigidum And Scrophularia Scorodonia
      5. Antiviral Effects Of Saikosaponins On Human Coronavirus 229E In Vitro
      6. Antiviral Natural Products And Herbal Medicines
      7. Chinese Medicinal Herb: A Clinical Monogragh Of Radix Bupleuri (Chai Hu)
      8. Comparison Between Evaporative Light Scattering Detection And Charged Aerosol Detection For The Analysis Of Saikosaponins
      9. Cytotoxic Triterpenoid Glycosides (Saikosaponins) From The Roots Of Bupleurum Chinense
      10. Determination Of Saikosaponins A, C, And D In Bupleurum Chinese Dc From Different Areas By Capillary Zone Electrophoresis
      11. Determination Of Saikosaponins In Radix Bupleuri By Hplc
      12. In Vitro Antiviral Activity Of A Saponin From Anagallis Arvensis, Primulaceae, Against Herpes Simplex virus And Poliovirus
      13. In Vivo And In Vitro Antiinflammatory Activity Of Saikosaponins
      14. Modulatory Effects Of Extracts Of Vinegar-Baked Radix Bupleuri And Saikosaponins On The Activity Of Cytochrome P450 Enzymes In Vitro
      15. Pharmacological Effects And Chemical Constituents Of Bupleurum
      16. Purposing Saikosaponins For The Treatment Of Covid-19
      17. Saikosaponin B2 Is A Naturally Occurring Terpenoid That Efficiently Inhibits Hepatitis C virus Entry
      18. Saikosaponins With Similar Structures But Different Mechanisms Lead To Combined Hepatotoxicity
      19. Saikosaponins: A Review Of Pharmacological Effects
      20. Species Discrimination Of Radix Bupleuri Through The Simultaneous Determination Of Ten Saikosaponins By High Performance Liquid Chromatography With Evaporative …
      21. The Characteristics Of A Microwave Extraction Process Used For Saikosaponins From Bupleurum Falcatum Root
      22. The Effects Of Saikosaponins On Biological Membranes
      23. Ultrasonic-Assisted Micellar Extraction And Cloud-Point Pre-Concentration Of Major Saikosaponins In Radix Bupleuri Using High Performance Liquid …

      Salicin
      (Salix babylonicaL.bark)

      1. Isolation of Salicin Derivatives from Homalium cochinchinensis and Their Antiviral Activities


      Salidroside
      (Rhodiola Rosea Extract)

      1. A Preliminary Study: The Anti-Proliferation Effect Of Salidroside On Different Human Cancer Cell Lines
      2. Approaches Of Rhodiola Kirilowii And Rhodiola Rosea Field Cultivation In Poland And Their Potential Health Benefits
      3. Assessing The Quality And Potential Efficacy Of Commercial Extracts Of Rhodiola Rosea L. By Analyzing The Salidroside And Rosavin Content And The …
      4. Biotechnological Approaches To Enhance Salidroside, Rosin And Its Derivatives Production In Selected Rhodiola Spp. In Vitro Cultures
      5. Comparison Of Phenylethanoids Content In Rhodiola Kirilowii And Rhodiola Rosea Roots Applying A Newly Developed Uplc-Ms/Ms Method
      6. Effects Of Rhodiola Rosea And Panax Ginseng On The Metabolic Parameters Of Rats Submitted To Swimming
      7. Effects Of Salidroside On Exhaustive Exercise‑Induced Oxidative Stress In Rats
      8. In Vivo Th1 And Th2 Cytokine Modulation Effects Of Rhodiola Rosea Standardised Solution And Its Major Constituent, Salidroside
      9. Novel Method Of Detection Of Phenylpropanoids Of Rhodiola Roots Species
      10. Performance Improvement In Human And Animal Athletes
      11. Phytochemistry Of Rhodiola Rosea
      12. Qualitative And Quantitative Analysis Of Different Rhodiola Rosea Rhizome Extracts By Uhplc-Dad-Esi-Msn
      13. Rapid Resolution Liquid Chromatography (Rrlc) Analysis For Quality Control Of Rhodiola Rosea Roots And Commercial Standardized Products
      14. Review Of The Molecular Genetics In Higher Plants Towards Salidrosid And Cinnamyl Alcohol Glycosides Biosynthesis In Rhodiola Rosea L.
      15. Rhodiola Plants: Chemistry And Biological Activity
      16. Rhodiola Rosea Exerts Antiviral Activity In Athletes Following A Competitive Marathon Race
      17. Salidroside Induces Cell-Cycle Arrest And Apoptosis In Human Breast Cancer Cells
      18. The Authenticity And Quality Of Rhodiola Rosea Products
      19. The Influence Of Rhodiola Rosea Extracts And Rosavin On Cutaneous Angiogenesis Induced In Mice After Grafting Of Syngeneic Tumor Cells
      20. The Pseudoendogenous Anabolic Steroid 1, 4-Androstadiene-3, 17-Dione Does Not Occur Naturally In Rhodiola Rosea L. Radix And Rhizome

       

       

      Salvadora persica

      Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease

      In December 2019, an outbreak of coronavirus disease 2019 (COVID-19) commenced in Wuhan, China and affected around 210 countries and territories in a matter of weeks. It has a phylogenetic similarity to SARS-CoV and it was named coronavirus 2 (SARS-CoV-2) and caused severe acute respiratory syndrome that could lead to death. One of the promising therapeutic strategies for virus infection is the search for enzyme inhibitors among natural compounds using molecular docking in order to obtain products with minimal side effects. COVID-19 virus main protease plays a vital role in mediating viral transcription and replication, introducing it as an attractive antiviral agent target. Metabolic profiling of the aqueous extract of Salvadora persicaL. (Salvadoraceae) aerial parts dereplicated eleven known flavonol glycosides using LC-HRESIMS. All the annotated flavonoids exhibited significant binding stability at the N3 binding site to different degrees, except isorhamnetin-3-O-β-D-glucopyranoside, when compared with the currently used COVID-19 main protease inhibitor, darunavir. Structural similarity between the identified flavonoids enabled the study of the relationship between their structure and interactions with the receptor in the N3 binding site of the COVID-19 main protease. The results indicate that the basic flavonol nucleus possesses activity itself. Moreover, the presence of a rutinose moiety at the 3 position of ring C and absence of an O-methyl group in ring B of the flavonol structure could increase the binding stability. This study provides a scientific basis for the health benefits of the regular use of S. persica as it leaches bioactive flavonoids in the aqueous saliva.

      samarangenin B
      (Limonium bicolor (Bag.) Kuntze)

      1. An Evidence Based Review On Oriental Medicine For The Treatment Of Herpes Simplex Infections And Their Availability In Iran
      2. Antiviral Activities Of Radix Isatidis Polysaccharide Against Pseudorabies virus In Swine Testicle Cells
      3. Antiviral Phytochemicals: An Overview
      4. In Vitro Antiviral Activity Of Prodelphinidin B-2 3, 3′-Di-O-Gallate From Myrica Rubra
      5. In Vitro Antiviral Screening Of Psidium Gujava L. Against Hsv-1 And Hsv-2 By Cpe Inhibition Assay
      6. Limonium Sinense And Gallic Acid Suppress Hepatitis C virus Infection By Blocking Early viral Entry
      7. Mechanism Of Action Of The Suppression Of Herpes Simplex virus Type 2 Replication By Pterocarnin A
      8. Mutagenic And Cytotoxic Activities Of Limonium Globuliferum Methanol Extracts
      9. Putranjivain A From Euphorbia Jolkini Inhibits Both virus Entry And Late Stage Replication Of Herpes Simplex virus Type 2 In Vitro
      10. Samarangenin B From Limonium Sinense Suppresses Herpes Simplex virus Type 1 Replication In Vero Cells By Regulation Of viral Macromolecular Synthesis
      11. The Complete Chloroplast Genome Sequence Of Limonium Sinense (Plumbaginaceae)
      12. Traditional Chinese Herbal Medicine As A Source Of Molecules With Antiviral Activity

      Saposhnikovia divaricata (Trucz.) Schischk. Extract
      (Saposhnikovia divaricata (Trucz.) Schischk root)

      1. A Preliminary Investigation On The Control Of Culex Pipiens Pallens With The Ethanol Extracts Of Five Umbelliferae Herbal Medicines
      2. Antiviral Chinese Medicinal Herbs Against Respiratory Syncytial virus
      3. Biologically Active Polysaccharides From Medicinal Plants Of The Far East
      4. Chromones And Coumarins From Saposhnikovia Divaricata (Turcz.) Schischk. Growing In Buryatia And Mongolia And Their Cytotoxicity
      5. Diversity Of Pharmacological Properties In Chinese And European Medicinal Plants: Cytotoxicity, Antiviral And Antitrypanosomal Screening Of 82 Herbal Drugs
      6. Effect Of Juice And Extracts From Saposhnikovia Divaricata Root On The Colon Cancer Cells Caco-2
      7. Ex Vivo And In Situ Evaluation Of ‘Dispelling‐Wind’ Chinese Medicine Herb–Drugs On Intestinal Absorption Of Chlorogenic Acid
      8. Growth Performance, Blood Cell Profiles, And Meat Quality Properties Of Broilers Fed With Saposhnikovia Divaricata, Lonicera Japonica, And Chelidonium Majus Extracts
      9. Saposhnikovia Divaricata—An Ethnopharmacological, Phytochemical And Pharmacological Review
      10. Study On Antifungal Activity Of Eight Plant Extracts On Botrytis Cinerea [J]
      11. Three New Coumarins From Saposhnikovia Divaricata And Their Porcine Epidemic Diarrhea virus (Pedv) Inhibitory Activity

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      savinin

      1. Chemistry Of Red Sanders
      2. Immunomodulatory Effect Of Arctigenin, A Lignan Compound, On Tumour Necrosis Factor‐Α And Nitric Oxide Production, And Lymphocyte Proliferation
      3. Isolation And Identification Of Antifungal Components From Juniperus Chinensis Cv. Kaizuca With Ethyl Acetate.
      4. Natural Products’ Role Against Covid-19
      5. Natural Virucidal Compounds In Foods
      6. Phytochemical Evaluation Of Tribal Drug Veerasingam Pattai Zanthoxylum Tetraspermum Wight And Arn Stem Bark
      7. Sars-Cov-2: An Update On Potential Antivirals In Light Of Sars-Cov Antiviral Drug Discoveries
      8. Savinin, A Lignan From Pterocarpus Santalinus Inhibits Tumor Necrosis Factor-Α Production And T Cell Proliferation
      9. The Distribution Of Lignanoids In The Order Coniferae
      10. Therapeutic Potential Of Pterocarpus Santalinus L.: An Update
      11. Uhplc-Ms Strategies And Applications For Bioanalyses Related To Pharmacokinetics And Drug Metabolism

      schisandrin
      (Schisandra chinensis extract)

      1. Current Knowledge Of Schisandra Chinensis (Turcz.) Baill. (Chinese Magnolia Vine) As A Medicinal Plant Species: A Review On The Bioactive Components …
      2. Dibenzocyclooctadiene Lignans From Schisandra Lancifolia And Their Anti-Human Immunodeficiency virus -1 Activities
      3. Diphenyl Dimethyl Bicarboxylate As An Effective Treatment For Chemical-Induced Fatty Liver In Rats
      4. Direct Chiral Separation Of Γ-Schizandrin Enantiomers By Rp-Hplc Using Chiralcel Od-Rh [J]
      5. Extraction And Separation Of Active Ingredients In Schisandra Chinensis (Turcz.) Baill And The Study Of Their Antifungal Effects
      6. Isolation And Anti-Hepatitis B virus Activity Of Dibenzocyclooctadiene Lignans From The Fruits Of Schisandra Chinensis
      7. Journal Metrics
      8. Neolignans From Schisandra Wilsoniana And Their Anti-Human Immunodeficiency virus -1 Activities
      9. Potential Of Schisandra Chinensis (Turcz.) Baill. In Human Health And Nutrition: A Review Of Current Knowledge And Therapeutic Perspectives
      10. Protein Tyrosine Phosphatase 1B (Ptp1B) And Α-Glucosidase Inhibitory Activities Of Schisandra Chinensis (Turcz.) Baill
      11. Schizandrin A Alleviates Lps-Induced Injury In Human Keratinocyte Cell Hacat Through A Microrna-127-Dependent Regulation
      12. Schizandrin A Enhances Chemosensitivity Of Colon Carcinoma Cells To 5-Fluorouracil Through Up-Regulation Of Mir-195
      13. Screening And Identification Of The Main Metabolites Of Schisantherin A In Vivo And In Vitro By Using Uhplc-Q-Tof-Ms/Ms

      Schizonepeta tenusfolia Briq extract
      (Schizonepeta tenusfolia Briq dried flower)

      1. Analysis Of Phytochemicals In Popular Medicinal Herbs By Hplc And Gc-Ms
      2. Anti‐Influenza Agents From Plants And Traditional Chinese Medicine
      3. Antiviral Activities Of Schizonepeta Tenuifolia Briq. Against Enterovirus 71 In Vitro And In Vivo
      4. Antiviral Activity Of Schizonepeta Tenuifolia Briquet Against Norovirus es Via Induction Of Antiviral Interferons
      5. Antiviral And Inflammatory Cellular Signaling Associated With Enterovirus 71 Infection
      6. Antiviral Chinese Medicinal Herbs Against Respiratory Syncytial virus
      7. Effect Of Jingjie Volatile Oil On Leukotrienes Levelsin Rats [J]
      8. Efficacy And Mechanism Of Mentha Haplocalyx And Schizonepeta Tenuifolia Essential Oils On The Inhibition Of Panax Notoginseng Pathogens
      9. Optimization Of Ultrasonic-Assisted Extraction Of Total Flavonoids From Schizonepeta Tenuifolia Briq By Response Surface Methodology
      10. Qualitative And Quantitative Studies On Impurities In Schizonepetin, A Novel Antiviral Agent, Using Hplc, Nmr And Ms
      11. Rp-Hplc Determination Of Hesperidin In Schizonepeta Tenuifolia Briq’S Extract
      12. Study On Antiviral Components In Vitro Of Ganmao Qingre Granules
      13. Study On The Effect And Mechanism Of Anti-Influenza A virus Of The Volatile Oil Of Herba Schizonepetae Briq. In Vitro [J]
      14. Study On The Effect Of Anti-Influenza virus Of The Volatile Oil Of Schizonepetae, Menthone And Pulegone [J]


      Selaginella moellendorffii Hieron extract
      (Selaginella moellendorfii Hieron herb)

      1. A New Neolignan From Selaginella Moellendorffii Hieron
      2. A New Pyrrole Alkaloid From Selaginella Moellendorfii Hieron
      3. A New Selaginellin From Selaginella Moellendorffii Inhibits Hepatitis B virus Gene Expression And Replication
      4. Antioxidant Chemical Constituents From The Herb Of Plantago Asiatica L.
      5. Bioactive Flavones And Biflavones From Selaginella Moellendorffii Hieron
      6. Diversity, Conservation Status And Medicinal Importance Of Selaginella Spp.
      7. New Adenine Analogues And A Pyrrole Alkaloid From Selaginella Delicatula
      8. New Inhibitors Of Matrix Metalloproteinases 9 (Mmp-9): Lignans From Selaginella Moellendorffii
      9. Two New Anthraquinone Derivatives And One New Triarylbenzophenone Analog From Selaginella Tamariscina
      10. Unciflavones A–F, Six Novel Flavonoids From Selaginella Uncinata (Desv.) Spring

      Semen Lepidii Semen Descurainiae extract
      (Eruca sativa Mill)

      1. A Metabolomics Approach To Studying The Effects Of Jinxin Oral Liquid On Rsv-Infected Mice Using Uplc/Ltq-Orbitrap Mass Spectrometry
      2. A Native Human Monoclonal Antibody Targeting Hcmv Gb (Ad-2 Site I)
      3. Chinese Medicinal Herbs For Childhood Pneumonia: A Systematic Review Of Effectiveness And Safety
      4. Combating Covid-19 With Integrated Traditional Chinese And Western Medicine In China
      5. Deploying Biomolecules As Anti-Covid-19 Agents
      6. Free Quantitative Proteomics Reveals Fibrinopeptide B And Heparin Cofactor Ii As Potential Serum Biomarkers In Respiratory Syncytial virus -Infected Mice Treated …
      7. Herbal Medicine For Treatment Of Children Diagnosed With Covid-19: A Review Of Guidelines
      8. In Silico Screening Of Chinese Herbal Medicines With The Potential To Directly Inhibit 2019 Novel Coronavirus
      9. Inula Viscosa (L.) Aiton Leaves And Flower Buds: Effect Of Extraction Solvent/Technique On Their Antioxidant Ability, Antimicrobial Properties And Phenolic Profile
      10. Label-Free Quantitative Proteomics Reveals Fibrinopeptide B And Heparin Cofactor Ii As Potential Serum Biomarkers In Respiratory Syncytial virus -Infected Mice Treated …
      11. Phytochemistry And Ethnopharmacology Of Some Medicinal Plants Used In The Kurdistan Region Of Iraq
      12. Phytochemistry And Pharmacological Values Of Rocket (Eruca Sativa Miller)–A Review
      13. The Experience Of Treating Patients With Pneumonia Secondary To The Coronavirus Disease 2019 Using The Guizhi Method Of Traditional Chinese Medicine
      14. Tong Xiaolin23, Li Aiguo23, Zhang Zhiyuan23, Chen Xiaoguang23, Li Ping23, Duan Jun23, Hua Chuanjin23, Zhao Dong23, Xu Yuan23, Shi Xiaoping23, Tian …
      15. Traditional Chinese Herbal Medication For Corona-virus 2019

      Silibinin
      (Milk Thistle Extract)

      1. Anti-Herpes virus Activity Of Silibinin, The Primary Active Component Of Silybum Marianum
      2. Antiviral Activity Of Silymarin Against Chikungunya virus
      3. Coadministration Of Milk Thistle And Indinavir In Healthy Subjects
      4. Differential In Vitro Effects Of Intravenous Versus Oral Formulations Of Silibinin On The Hcv Life Cycle And Inflammation
      5. Effect Of Silymarin (Milk Thistle) On Liver Disease In Patients With Chronic Hepatitis C Unsuccessfully Treated With Interferon Therapy: A Randomized Controlled Trial
      6. Hepatoprotective And Antiviral Functions Of Silymarin Components In Hcv Infection
      7. Identification Of Hepatoprotective Flavonolignans From Silymarin
      8. Milk Thistle For Treatment Of Nonalcoholic Fatty Liver Disease
      9. Milk Thistle In Liver Diseases: Past, Present, Future
      10. Novel Method Boosts Milk Thistle Liver Concentration 10-Fold!
      11. Phytoliposome-Based Silibinin Delivery System As A Promising Strategy To Prevent Hepatitis C virus Infection
      12. Safety And Toxicity Of Silymarin, The Major Constituent Of Milk Thistle Extract: An Updated Review
      13. Silibinin Is A Potent Antiviral Agent In Patients With Chronic Hepatitis C Not Responding To Pegylated Interferon/Ribavirin Therapy
      14. Silibinin: A Promising Anti-Neoplastic Agent For The Future? A Critical Reappraisal
      15. Silymarin For Hepatitis C virus Infection
      16. Stephen J Polyak1, 2, 3*, Nicholas H Oberlies4, Eve-Isabelle Pécheur5, Harel Dahari6, 7, 8, Peter Ferenci9
      17. Successful Hcv Eradication And Inhibition Of Hiv Replication By Intravenous Silibinin In An Hiv–Hcv Coinfected Patient
      18. Targeting Stat3 With Silibinin To Improve Cancer Therapeutics
      19. Treatment Of Hepatitis C With Milk Thistle?

      Silymarin
      (Milk Thistle Extract)

      1. Antiviral Activities Of Silymarin And Derivatives
      2. Antiviral Activity Of Silymarin Against Chikungunya virus
      3. Antiviral Activity Of Silymarin Against Mayaro virus And Protective Effect In virus -Induced Oxidative Stress
      4. Antiviral Activity Of Silymarin In Comparison With Baicalein Against Ev-A71
      5. Antiviral Effect Of Silymarin Against Zika virus In Vitro
      6. Application Of Spray Drying Particle Engineering To A High-Functionality/Low-Solubility Milk Thistle Extract: Powders Production And Characterization
      7. Biology Of Milk Thistle (Silybum Marianum) And The Management Options For Growers In North‐Western Pakistan
      8. Clinical And Pharmacological Applications Of Silymarin Components At Cellular And Molecular Level: A Review
      9. Coadministration Of Milk Thistle And Indinavir In Healthy Subjects
      10. Effect Of Silymarin (Milk Thistle) On Liver Disease In Patients With Chronic Hepatitis C Unsuccessfully Treated With Interferon Therapy: A Randomized Controlled Trial
      11. Effects Of Silymarin Supplementation In Patients With Chronic Hepatitis C Receiving Peg-Ifn+ Ribavirin Antiviral Therapy. A Placebo-Controlled Double Blind Study
      12. Evaluation Of The Role Of The Antioxidant Silymarin In Modulating The In Vivo Genotoxicity Of The Antiviral Drug Ribavirin In Mice
      13. Evaluation Of The Role Of The Antioxidant Silymarin In Modulating The In Vivo Genotoxicity Of The Antiviral Drug Ribavirin In The Laboratory Mice Mus Muscuius
      14. Hepatoprotective And Antiviral Functions Of Silymarin Components In Hcv Infection
      15. Herbal Product Use By Persons Enrolled In The Hepatitis C Antiviral Long‐Term Treatment Against Cirrhosis (Halt‐C) Trial
      16. Identification Of Hepatoprotective Flavonolignans From Silymarin
      17. In Vitro Antiviral And Antioxidant Activities Of Silymarin And Panax Ginseng On Vero Cells Infected With Bovine Ephemeral …
      18. In Vitro Effects On Biofilm Viability And Antibacterial And Antiadherent Activities Of Silymarin
      19. Metabolism, Transport And Drug–Drug Interactions Of Silymarin
      20. Milk Thistle And The Liver Recent Findings
      21. Milk Thistle And The Liver: Recent Findings
      22. Milk Thistle For Treatment Of Nonalcoholic Fatty Liver Disease
      23. Novel Method Boosts Milk Thistle Liver Concentration 10-Fold!
      24. Potential Renoprotective Effects Of Silymarin Against Nephrotoxic Drugs: A Review Of Literature
      25. Randomised Double-Blinded Trial Evaluating Silymarin For Chronic Hepatitis C In An Egyptian Village: Study Description And 12-Month Results
      26. Renoprotective Effect Of Silymarin On Gentamicin-Induced Nephropathy
      27. Safety And Toxicity Of Silymarin, The Major Constituent Of Milk Thistle Extract: An Updated Review
      28. Semisynthesis, Cytotoxicity, Antiviral Activity, And Drug Interaction Liability Of 7-O-Methylated Analogues Of Flavonolignans From Milk Thistle
      29. Silibinin And Stat3: A Natural Way Of Targeting Transcription Factors For Cancer Therapy
      30. Silibinin Is A Potent Antiviral Agent In Patients With Chronic Hepatitis C Not Responding To Pegylated Interferon/Ribavirin Therapy
      31. Silymarin Ascending Multiple Oral Dosing Phase I Study In Noncirrhotic Patients With Chronic Hepatitis C
      32. Silymarin Flavonolignans: Structure–Activity Relationship And Biosynthesis
      33. Silymarin For Hepatitis C virus Infection
      34. Silymarin Inhibits In Vitro T-Cell Proliferation And Cytokine Production In Hepatitis C virus Infection
      35. Silymarin Is A Potent Antiviral Drug Against Hcv In Nonresponders To Peginterferon/Ribavirin–Dose Finding And viral Kinetics Studies
      36. Silymarin Use And Liver Disease Progression In The Hepatitis C Antiviral Long‐Term Treatment Against Cirrhosis Trial
      37. Silymarin: A Potent Hepatoprotective Agent In Poultry Industry
      38. Stephen J Polyak1, 2, 3*, Nicholas H Oberlies4, Eve-Isabelle Pécheur5, Harel Dahari6, 7, 8, Peter Ferenci9
      39. Studies In Natural Products Chemistry: Chapter 14. Silymarin Flavonolignans: Structure–Activity Relationship And Biosynthesis
      40. Toxicology And Carcinogenesis Studies Of Milk Thistle Extract (Cas No. 84604-20-6) In F344/N Rats And B6C3F1 Mice (Feed Studies).
      41. Treatment Of Hepatitis C With Milk Thistle?
      42. Tyrosinase Inhibitory Study Of Flavonolignans From The Seeds Of Silybum Marianum (Milk Thistle)

      Solanum rantonnetii aerial parts extact

      (Lycianthes rantonnetii Bitter)

      1. Potent Antiviral Activity Of Solanum Rantonnetii And The Isolated Compounds Against Hepatitis C virus In Vitro

      SOmniferine A
      (Ashwaganda Extract)

      1. Evaluation of Traditional Ayurvedic Preparation for Prevention and Management of the Novel Coronavirus (SARS-CoV-2) Using Molecular Docking Approach Since the emergence of novel Coronavirus (SARS-CoV-2) infection in Wuhan, China in December 2019, it has now spread to over 205 countries. The ever-growing list of globally spread corona virus-19 disease (COVID19) patients has demonstrated the high transmission rate among human population. Although 12 new drugs are being tried for management of COVID19, currently there are no FDA approved drugs or vaccines to prevent and treat the infection of the SARS-CoV-2. Considering the current state of affairs, there is an urgent unmet medical need to identify novel and effective approaches for prevention and treatment of COVID19 by re-evaluating the knowledge of traditional medicines and repurposing of drugs. Here, we used molecular docking approach to explore the beneficial roles of an array of phytochemicals and active pharmacological agents present in the Indian herbs (Tulsi, Haldi, Giloy, Black pepper, Ginger, Clove, Cardamom, lemon, and Ashwagandha) which are widely used in the preparation of Ayurvedic medicines in the form of Kadha to control various respiratory disorders such as cough, cold and flu. The evaluation was made based on the docking scores calculated by AutoDock Vina. Our study has identified an array of phytochemicals present in these herbs which have significant docking scores and potential to inhibit different stages of SARS-CoV-2 infection as well as other Coronavirus target proteins. Molecular docking also indicated that, the phytochemicals present in these herbs possess significant anti-inflammatory property. Overall our study provides scientific justification in terms of binding of active ingredients present in different plants used in Kadha preparation with viral proteins and target proteins for prevention and treatment of the COVID19. This preparation can boost individual’s immunity and inhibit the viral severity by interfering at different stages of virus multiplication in the infected person. Our study predicts that an array of the phytochemicals such as Withaferin A, Withanolide B, Withanolide, Withanone, Campesterol, Cyclocurcumin,Somniferine A,Stigmasterol, Eriodictyol, Isopiperine, Oleanolic acid, Rhamnetin, Orientin, Quercetin, Piperine, Vicenin etc. found in the preparation of the Kadha, have significant binding affinity with the many of these inflammatory mediators or the molecules involved in this process (Table 7). It is well known that, NF-κB is the master regulator for several genes such as COX-2, VEGF (vascular endothelial growth Factor), proinflammatory cytokines (IL-1, IL-2, IL-6, and TNFα), chemokines (e.g., IL-8, MIP-1α, and MCP1), adhesion molecules, immunoreceptors, growth factors, and other agents involved in proliferation and invasion. NF-κB activation is mediated by two distinctly different redoxrelated signalling pathways. The first pathway involves NIK/IKK whereas second pathway involve MAPKs and both causes the induction of transcriptional activation of NF-κB. NF-κBinducing kinase (NIK) is a key mediator of the non-canonical NF-κB signalling pathway. NF-κB is also one of the main inducible transcription factors shown to respond directly to oxidative stress. Oxidative stress activates nuclear factor-inducing kinase (NIK)/IκB kinase (IKK) and mitogen-activated protein kinases (MAPKs). NIK/IKK and MAPK pathways activate NF-κB and migrates to the nucleus and binds to κ elements on DNA in enhancers and promoter regions. Various herbs have potential to control inflammation-associated disease by decreasing the production of the pro-inflammatory mediators by suppressing pro-inflammatory pathways (Pan et al., 2011). Our study also predicted that phytochemicals found in the Kadha have significant binding affinity with NIK (Table 7) which can stop NF-κB mediated downstream events. In a very recent study, Huang et al (2020) have shown that the patients infected with SARS-CoV-2 had high amounts of IL1, IFNγ, IP10, and MCP1, which can mediate cytokine storm associated multi-organ damage. At the same time, SARS-CoV-2 infection also initiates increased secretion of T-helper-2 (Th2) cytokines (eg, IL4 and IL10) which suppress inflammation (Huang et al., 2020). The increased secretion of inflammatory mediators was also associated with moderation of helper T cell responses in COVID19 patients.
      2. Sars-cov-2 host entry and replication inhibitors from Indian ginseng: an in-silico approach Withania somnifera (Solanaceae) (L.) Dunal, popularly known as ‘Ashwagandha’ and ‘Indian Ginseng’ is a prime medicinal plant of Ayurvedic and indigenous medicines from India and has been used as an herbal tonic and healthy food to treat various kinds of diseases and human ailments (Gurav & Gurav, ). W. somnifera contains alkaloids, flavonoids and steroidal lactones namely withanine, somniferine, somnine, somniferinine, withananine, pseudowithanine tropane, pseudo-tropine, choline, anaferine, anahydrine, isopelletierine, withaferin A and B, 27-deoxywithaferin, dihydrowithaferin A, 17-hydroxywithaferin A, withanolide A, B, C, D, E, G, J, L, M, N, O, P, Q, R and S, withanone, withanosine II, III, IV, V, VI, X and XI, Quercetin, and Quercetin-3-O-galactosyl-rhamnosyl-glucoside (QGRG; Abraham et al., ; Elsakka et al., ; Gupta & Rana, ; Krison & Glotter, ; Matsuda et al., ). Ashwagandha is widely claimed to have hepatoprotective, anxiolytic, antidepressant, nootropic, antimicrobial, anti-inflammatory, antioxidant, anti-stress, anticonvulsant, cardio-protective, antitumor, anti-genotoxic, anti-Parkinson and immunomodulatory properties (Dar et al., ; Gurav et al., ).

       

      Stigmasterol
      (soybean)

      1. 17 Nutritional Value Of Soybean
      2. Antiviral Action Of Synthetic Stigmasterol Derivatives On Herpes Simplex virus Replication In Nervous Cells In Vitro
      3. Antiviral Activity Of 7-Keto-Stigmasterol Obtained From Green Antarctic Algae Prasiola Crispa Against Equine Herpesvirus 1
      4. Flavonoids: A Nutritional Protection Against Oxidative And Uv Induced Cellular Damages
      5. From Soybean Phytosterols To Steroid Hormones
      6. Importance Of Phytosterols And Their Determination In Herbal Medicines
      7. Phytochemical Constituents From The Leaves Of Soybean [Glycine Max (L.) Merr.]
      8. Phytochemical Studies And Fatty Acid Analysis Of The Stems Of Polyalthia Suberosa (Roxb.)
      9. Phytochemicals Components As Bioactive Foods
      10. Phytochemicals Of Utraceutical Importa Ce: Their Role I Health Ad Diseases
      11. Phytopharmaceutical Applications Of Nutraceutical And Functional Foods
      12. Plant-Derived Natural Products In Drug Discovery And Development: An Overview
      13. Potential Of Stigmasterol From Etoac Extract Melochia Umbellata (Houtt) Stapf Var. Visenia As Dengue Antivirus
      14. Preliminary Phytochemical And Pharmacological Studies Of Aleurites Moluccana Leaves [L.] Willd
      15. Salt Stress Enhancement Of Antioxidant And Antiviral Efficiency Of Spirulina Platensis
      16. Soybean Bioactive Components And Their Implications To Health—A Review
      17. Therapeutic Potential Of Brassinosteroids In Biomedical And Clinical Research


St. Rophanthus Gratus Seed (Ouabain)

  1. Solid evidence- ouabain is an effective therapeutic for the treatment of COVID-19
  2. Solid evidence: ouabain is an effective therapeutic for the treatment of COVID-19
    Worldwide efforts are underway to find therapeutics for the treatment of covid-19.. In several test series, ouabain has been identified as a highly active antiviral agent. Ouabain (known as g-Strophanthin in German) has been used successfully for decades in the treatment of heart disease, particularly in Germany. Extensive clinical experience with this active ingredient is available. These also include experience with infectious diseases. As early as 1933, Fraenkel pointed out the successful treatment of pneumonia with Ouabain. “Since the large doses (of Strophanthin ) have become commonplace in pneumonia, the acute heart failure peculiar to it has lost its terror.” [1] In 1960, Walter Neugebauer reported, “In acute circulatory failure and infectious diseases, Strophanthin will probably be hard to do without.” [2]
    Antiviral effects of Ouabain.
    Current research findings confirm these clinical experiences. Ouabain has pronounced antiviral effects. In several series of tests, cardiac glycosides have been identified as highly active antiviral compounds. Digoxin, digitoxin, and ouabain which are known drugs for therapy of heart disease, show efficacy against a broad spectrum of viruses in vitro and in vivo. Digoxin and ouabain also have excellent effects against SARS-CoV-2 viruses at nanomolar concentrations [3-7]. Viral titers after single-dose treatment with ouabain and digoxin showed >99% inhibition of SARS-CoV-2 replication. When administered in the post-entry phase, ouabain and digoxin significantly inhibited viral mRNA expression and protein expression. When administered in the host entry phase of the viral cycle, digoxin shows no effective antiviral activity. In contrast, ouabain inhibits approximately 50% of viral mRNA expression and protein expression even at the entry stage [6].
    In a recent paper, a US research group led by Harvey Pollard has been able to show that the cardiac glycosides ouabain, digitoxin and digoxin block the entry of SARS-CoV-2 spike-pseudotyped viruses into human lung cells, thereby preventing the infectivity of native SARS-CoV-2 [8]. Cardiac glycosides block the binding reaction between ACE2 and the viral spike (S) protein, preventing virus entry into target cells. The authors conclude from their research that “Ouabain, digitoxin and digoxin competitively inhibit ACE2 binding to the SARS-CoV-2 Receptor Binding Domain (RBD), and block virus penetration and infectivity in human lung cells.” It is therefore possible to use these drugs for COVID- 19 therapy.”

 

 


      1. synephrine
        (Citrus Aurantium Extract Powder)

        1. Acridone Alkaloids From The Stem Bark Of Citrus Aurantium Display Selective Cytotoxicity Against Breast, Liver, Lung And Prostate Human Carcinoma Cells
        2. An Overview Of Citrus Aurantium Used In Treatment Of Various Diseases
        3. Cent Percent Safe Centum Plants For Antiobesity
        4. Changes Of Peel Essential Oil Composition Of Citrus Aurantium L. During Fruit Maturation In Iran
        5. Citrus Peel Extract Incorporated Ice Cubes To Protect The Quality Of Common Pandora
        6. Comparative Effects Of Peel Extract From Nigerian Grown Citrus On Body Weight, Liver Weight And Serum Lipids In Rats Fed A High-Fat Diet
        7. Comparison Of Aurantii Fructus Immaturus And Aurantii Fructus Based On Multiple Chromatographic Analysis And Chemometrics Methods
        8. Comprehensive Utilization Of Citrus By-Products
        9. Contraceptive Effect Of Citrus Aurantifolia Juice Vaginal Douche On Reproductive Histomorphology Of Adult Female Wistar Rats.
        10. Effects Of Drying Methods On Phytochemical Compounds And Antioxidant Activity Of Physiologically Dropped Un-Matured Citrus Fruits
        11. Evaluation Of Antimicrobial Activity Of Zitritide, A Natural And Organic Antimicrobial Fogging Solution With Special Reference For Infection Prevention And Control …
        12. Evaluation Of The Inhibitory Effect Of Some Citrus Juices In Bacteria Klebsiellae Pneumonia In Vitro
        13. Flavonoids And Furocoumarins In Bergamot, Myrtle-Leaved Orange, And Sour Orange Juices: Distribution And Properties
        14. Fructus Immaturus Aurantii – Zhishi/Fructus Aurantii – Zhiqiao
        15. Identification Of Bioactive Composition And Antioxidant Activity In Young Mandarin Fruits
        16. Pharmacological Actions Of Citrus Species
        17. Phytochemical Analysis And Inhibitory Effect Of Citrus Aurantium L.(Bitter Orange) Leaves On Some Bacterial Isolates In Vitro
        18. Phytochemical Profile And Antioxidant Activity Of Physiological Drop Of Citrus Fruits
        19. Simultaneous Analysis Of Adrenergic Amines And Flavonoids In Citrus Peel Jams And Fruit Juices By Liquid Chromatography: Part 2
        20. Cytotoxicity, antiviral and antimicrobial activities of alkaloids, flavonoids, and phenolic acids
        21. Natural antiviral compounds

        Taxillus sutchuenensis extract
        (Taxillus sutchuenensis (Lecomte ) Danser)

        1. Activity Of Compounds From Taxillus Sutchuenensis As Inhibitors Of Hcv Ns3 Serine Protease
        2. Pharmacognostical And Pharmacological Evaluation Of Ammannia Baccifera
        3. Flavonoids: promising natural compounds against viral infections
        4. Recently, kaempferol-3,7-bisrhamnoside isolated from Chinese medicinal Taxillus sutchuenensis was shown to have potent in vitro activity on HCV NS3 protease function [144]
        5. Inhibition of SARS-CoV 3CL protease by flavonoids

         

thapsigargin

      1. Emergent SARS-CoV-2 variants: comparative replication dynamics and high sensitivity to thapsigargin

 

      1. Tinocordifolin
        (Tinospora cordifolia)

        1. A Brief Review On Some Medicinal Plants Of Uttarakhand
        2. A Review On Therapeutic Multipurpose Medicinal Use Of Tinospora Cordifolia
        3. Antimicrobial Activity Of Indian Medicinal Plants, Azadirachta Indica, Carica Papaya, Curcuma Longa, Moringa Oleifera And Tinospora Cordifolia: A Review
        4. Complex Effects Of Ayurvedic Formulation: Guduchi And Madhuyashti On Different Components Of Life History May Elude The Elixir Effect
        5. Immunity Booster Herbs And Their Conservation-A Review
        6. Pharmacological Potential Of Tinospora Cordifolia (Willd.) Miers Ex Hook. & Thoms.(Giloy): A Review
        7. Prevention Of Hepatotoxicity Due To Anti Tuberculosis Treatment: A Novel Integrative Approach
        8. Review On Trisama-An Unexplored Ancient Ayurvedic Formulation
        9. Studies On Chemical And Biological Control Of Leaf Spot Disease Of Tinospora Cordifolia Caused By Colletotrichum Spp
        10. Tinospora Cordifolia: Ethnobotany, Phytopharmacology And Phytochemistry Aspects

         

         

        Tinocordifolioside

        (Tinospora cordifolia)

        1. A Review On Therapeutic Multipurpose Medicinal Use Of Tinospora Cordifolia
        2. An Overview On Hepatoprotective Activity Of Natural Products
        3. Complex Effects Of Ayurvedic Formulation: Guduchi And Madhuyashti On Different Components Of Life History May Elude The Elixir Effect
        4. Evaluation Of Analgesic, Antipyretic And Anti-Inflammatory Effects Of Methanol Extract Of Traditional Herbal Medicine Using Rodents
        5. Indian Traditional Ayurvedic Treatment Regime For Novel Coronavirus , Covid-19
        6. Pharmacological Potential Of Tinospora Cordifolia (Willd.) Miers Ex Hook. & Thoms.(Giloy): A Review
        7. Prevention Of Hepatotoxicity Due To Anti Tuberculosis Treatment: A Novel Integrative Approach
        8. Review On Pharmacological Profile Of Medicinal Vine: Tinospora Cordifolia
        9. Studies On Chemical And Biological Control Of Leaf Spot Disease Of Tinospora Cordifolia Caused By Colletotrichum Spp
        10. Studies On In Vitro Plant Regeneration And Chemo–Profiling Of Tinospora Cordifolia (Willd)
        11. Tinospora Cordifolia: Ethnobotany, Phytopharmacology And Phytochemistry Aspects

        Tinosporide
        ((Tinospora cordifolia))

        1. A Comparative Study Of Radioprotection By Four Indian Medicinal Herbs Against Genotoxicity Induced By Sub-Lethal Gamma Irradiation In Swiss Albino Mice
        2. A Review On Therapeutic Multipurpose Medicinal Use Of Tinospora Cordifolia
        3. Antimicrobial Activity Of Indian Medicinal Plants, Azadirachta Indica, Carica Papaya, Curcuma Longa, Moringa Oleifera And Tinospora Cordifolia: A Review
        4. Anti-Tumor Activity Of Four Ayurvedic Herbs In Dalton Lymphoma Ascites Bearing Mice And Their Short-Term In Vitro Cytotoxicity On Dla-Cell-Line
        5. Antiviral Compound Screening, Peptide Designing, And Protein Network Construction Of Influenza A virus (Strain A/Puerto Rico/8/1934 H1N1)
        6. Comparative Evaluation Of Efficacy And Safety Of “Septilin Syrup” With Prophylactic Antibiotics, In Preventing Postoperative Infections In Children
        7. Functional Foods And Herbs As Potential Immunoadjuvants And Medicines In Maintaining Healthy Immune System: A Commentary
        8. Herbal Plants Used In Treatment Of Rheumatoid Arthritis: A Review
        9. Identification Of Endophytic Fungi From The Medicinal Plants Of Biligirirangana Hill, Karnataka
        10. Natural Remedies For Heart Diseases
        11. Panchatiktha Kwatha Ch
        12. Phytochemical Investigation And Isolation Of New Compounds From The Stems Of Tinospora Cordifolia Miers
        13. Some Folk Medicinal Herbs Of Solan Valley, Himachal Pradesh
        14. Studies On In Vitro Plant Regeneration And Chemo–Profiling Of Tinospora Cordifolia (Willd)
        15. Tinospora Cordifolia: A Novel Bioactive Ingredient For Edible Films For Improved Lipid Oxidative And Microbial Stability Of Meat Products
        16. Tinospora Cordifolia: Ethnobotany, Phytopharmacology And Phytochemistry Aspects
        17. Uses Of Medicinal Plants In Panchakarma Ayurvedic Therapy

        Trichostachine
        (Piper hancei Maxim)

        1. A Review On Diversified Use Of The King Of Spices: Piper Nigrum (Black Pepper)
        2. A Review On Study Of Medicinal Uses Of Some Aromatic Plants
        3. Prevention And Treatment Of Different Health Problems By Common Peoples Diet (Haleem)

        Triterpenoid saponins
        (Trichosanthes kirilowii extract (MongolianSnakegourd Fruit))

        1. An Introduction To Medicinally Important Trees
        2. Ancient And Recent Medicinal Uses Of Cucurbitaceae Family
        3. Antiproliferative Compounds From Hydnophytum Formicarium.
        4. Antiviral Triterpenoid Saponins From The Roots Of Ilex Asprella
        5. Herbal Plants And Plant Preparations As Remedial Approach For viral Diseases
        6. Inhibitory Effect Of Some Triterpenoid Saponins On Glucose Transport In Tumor Cells And Its Application To In Vitro Cytotoxic And Antiviral Activities
        7. Mechanism Of Antiviral Activity Of Triterpenoid Saponins
        8. New Antiviral Triterpenoid Saponins From Maesa Lanceolata
        9. Phytochemical And Pharmacological Investigation Of Melia Azedarach Leaves For Antiurolithiatic Activity.
        10. Plantas Com Efeito Na Aids-Sida-Hiv Positivo
        11. Positive Selection Of Squalene Synthase In Cucurbitaceae Plants
        12. Preliminary Studies Of Antiviral Activity Of Triterpenoid Saponins: Relationships Between Their Chemical Structure And Antiviral Activity
          Radix Bupleuri: A Review Of Traditional Uses, Botany, Phytochemistry, Pharmacology, And Toxicology
        13. Structure And In Vitro Antiviral Activity Of Triterpenoid Saponins From Calendula Arvensis
        14. Traditional Chinese Herbal Medicine As A Source Of Molecules With Antiviral Activity
        15. Uralsaponins M–Y, Antiviral Triterpenoid Saponins From The Roots Of Glycyrrhiza Uralensis


        Umbelliferone
        (Ruta graveolens L.)

        1. Biological Activities Of Constituentsfrom Psychotria Spectabilis
        2. Biological Synthesis Of Coumarins In Escherichia Coli
        3. Bioprospecting For Drug Research And Functional Foods For The Prevention Of Diseases—Role Of Flavonoids In Drug Development
        4. Biotechnological Production Of Coumarins
        5. Chemical Ecology Of Ruta Sp.: Voc, Chemotaxonomy And Allelochemistry
        6. Complementary And Alternative Approach To Heal Cancer: A Review
        7. Elicitors Enhance Alkaloid Yield In Catharanthus Roseus
        8. Methyltransferases From Ruta Graveolens L.: Molecular Biology And Biochemistry
          Natural Product Coumarins: Biological And Pharmacological Perspectives
        9. Pharmacological Activities And Biologically Active Compounds Of Bulgarian Medicinal Plants
        10. Plants Secondary Metabolites: The Key Drivers Of The Pharmacological Actions Of Medicinal Plants
        11. Ruta Graveolens Cultures As Screening Resources For Phyto-Pharmaceuticals: Bio-Prospecting, Metabolic Phenotyping And Multivariate Analysis
        12. Rutamarin: Efficient Liquid–Liquid Chromatographic Isolation From Ruta Graveolens L. And Evaluation Of Its In Vitro And In Silico Mao-B Inhibitory Activity
        13. Translational Role Of Natural Coumarins And Their Derivatives As Anticancer Agents


        Ursolic acid
        (Loquat Leaf Extract)

        1. Analysis Of Antioxidative And Antiviral Biomarkers Β-Amyrin, Β-Sitosterol, Lupeol, Ursolic Acid In Guiera Senegalensis Leaves Extract By Validated Hptlc …
        2. Anti-Inflammatory Effect Of Compound Radix Isatidis Granules [J]
        3. Antiproliferative And Antiviral Mechanism Of Ursolic Acid In Cervical Carcinoma Cell Lines
        4. Antiproliferative And Antiviral Mechanisms Of Ursolic Acid And Dexamethasone In Cervical Carcinoma Cell Lines
        5. Bioactive Compounds Of Loquat (Eriobotrya
        6. Bioactive Compounds Of Loquat (Eriobotrya Japonica (Thunb.) L.)
        7. Eriobotrya Japonica
        8. Loquat (Eriobotrya Japonica) Extract Prevents Dexamethasone-Induced Muscle Atrophy By Inhibiting The Muscle Degradation Pathway In Sprague Dawley Rats
        9. Loquat Leaf Extract Enhances Myogenic Differentiation, Improves Muscle Function And Attenuates Muscle Loss In Aged Rats
        10. Nutritional And Composition Of Fruit Cultivars: Loquat (Eriobotrya Japonica Lindl.)
        11. The Inhibitory Effects Of Pentacyclic Triterpenes From Loquat Leaf Against Th17 Differentiation
        12. Toxic Myopathy Induced By The Ingestion Of Loquat Leaf Extract
        13. Ursolic Acid: A Novel Antiviral Compound Inhibiting Rotavirus Infection In Vitro

        ” alt=”” width=”332″ height=”501″ data-src=”https://theinterstellarplan.com/wp-content/uploads/2020/07/Valinomycin.jpg” />

        Valinomycin
        (Bacterium streptomyces)

        1. An Introductory Chapter: Secondary Metabolites
        2. Antiparasitics From Microorganisms
        3. Bioactive Compounds From Marine Actinomycetes
        4. Fighting virus es With Antibiotics: An Overlooked Path
        5. Isolation And Purification Of Two Metabolites (Kgg32-A And Kgg32-B) From A Soil Bacterium, Streptomyces Sp., Kgg32
        6. Ivermectin, Antiviral Properties And Covid-19: A Possible New Mechanism Of Action
        7. Major Source Of Marine Actinobacteria And Its Biomedical Application
        8. Mass Production Of Natural Products From Microbes Derived From Sponges And Corals

        ” alt=”” width=”194″ height=”259″ data-src=”https://theinterstellarplan.com/wp-content/uploads/2020/07/Verbascum-thapsus.jpg” data-srcset=”https://theinterstellarplan.com/wp-content/uploads/2020/07/Verbascum-thapsus.jpg 194w, https://theinterstellarplan.com/wp-content/uploads/2020/07/Verbascum-thapsus-109×146.jpg 109w, https://theinterstellarplan.com/wp-content/uploads/2020/07/Verbascum-thapsus-37×50.jpg 37w, https://theinterstellarplan.com/wp-content/uploads/2020/07/Verbascum-thapsus-56×75.jpg 56w” data-sizes=”(max-width: 194px) 100vw, 194px” />
        Verbascum thapsus L
        (Mullein Extract)

        1. Antibacterial And Anti-Adherent Activity Of Great Mullein (Verbascum Thapsus L.) Ethanolic Extract On In Vitro Biofilm Formation Of Three Oral Streptococci
        2. Antimicrobial Activity Of Aqueous-Alcoholic Extracts And The Essential Oil Of Verbascum Thapsus L
        3. Antimicrobial Activity Of Three Endemic Verbascum Species
        4. Antimicrobial Potential Of The Leaves Of Common Mullein (Verbascum Thapsus L., Scrophulariaceae) On Microorganisms Isolated From Urinary Tract Infections
        5. Anti-Staphylococcal Activity Of Verbascum Thapsus L. Against Methicillin-Resistant Staphylococcus Aureus.
        6. Antiviral Effect And Mode Of Action Of Methanolic Extract Of Verbascum Thapsus L. On Pseudorabies virus (Strain Rc/79)
        7. Biological Activity Of Common Mullein, A Medicinal Plant
        8. Extensive Phytochemistry, Comprehensive Traditional Uses, And Critical Pharmacological Profile Of The Great Mullein: Verbascum Thapsus L
        9. In Vitro Culture Of Common Mullein (Verbascum Thapsus L.)
        10. In Vitro Influences Of Sugar Nutrition And Light Condition On Accumulation Of Some Phytochemicals In Verbascum Thapsus L …
        11. Micromorphology, Pharmacognosy, And Bio‐Elemental Analysis Of An Important Medicinal Herb: Verbascum Thapsus L.
        12. Optimization Of Ultrasound‐Assisted Extraction Of Functional Polysaccharides From Common Mullein (Verbascum Thapsus L.) Flowers
        13. Preparation Of Antibacterial Cotton Wound Dressing By Green Synthesis Silver Nanoparticles Using Mullein Leaves Extract
        14. Production Of Verbascoside And Its Analogues In In Vitro Cultures Of Verbascum Thapsus L.
        15. Study Of Sedative, Pre-Anesthetic, And Anti-Anxiety Effects Of Verbascum Thapsus L. Extract Compared With Diazepam In Rats
        16. The Evaluation Of Sterile Solutions Of Ilwensisaponin A And C From Verbascum Pterocalycinum Var. Mutense Hub.-Mor. On Antiviral, Antinociceptive And Anti …
        17. The Study Of The Verbascum Thapsus L. Herb Element Content
        18. Traditional Uses And Biological Activities Of Verbascum Species
        19. Verbacoside: A New Luteolin Glycoside From Verbascum Thapsus

        ” alt=”” width=”240″ height=”351″ data-src=”https://theinterstellarplan.com/wp-content/uploads/2020/07/Vicenin.jpg” />
        Vicenin
        (Desmodium styracifolium extract)

        1. Advance On The Flavonoid C-Glycosides And Health Benefits
        2. Herbal Products In Hypertension: Paradox Or, Paragon
        3. Protective Roles Of Flavonoids And Flavonoid-Rich Plant Extracts Against Urolithiasis: A Review

        ” alt=”” width=”295″ height=”274″ data-src=”https://theinterstellarplan.com/wp-content/uploads/2020/07/vincamine.jpg” />

        vincamine
        (Catharanthus roseus （L.）G. Don)

        1. Accumulation Effects Of Salicylic Acid Saccharide Carboxylate On The Alkaloids In Catharanthus Roseus Cells
        2. Alkaloids Of Catharanthus Roseus And Their Hypoglycemic Activity/Tiong Soon Huat
        3. Biomedical Importance Of Indoles
        4. Bodiversity And Antifungal Properties Of Endophytes From The Madagascar Medicinal Plants Centella Asiatica (L.) Urb. And Catharanthus Roseus (L.) G
        5. In Vitro Studies, Biosynthesis Of Secondary Metabolites And Pharmacological Utility Of Catharanthus Roseus (L.) G. Don.: A Review
        6. Natural Antiviral Compounds
        7. Pharmaceutical Sciences
        8. Phytochmical Studies On The Medicinal Herb Catharanthus Pusillus
        9. Production Of Indole Alkaloids In Hairy Root Cultures Of Catharanthus Roseus L. And Their Antimicrobial Activity
        10. The Contribution Of The Plant Kingdom To Medicine

        ” alt=”” width=”353″ height=”425″ data-src=”https://theinterstellarplan.com/wp-content/uploads/2020/07/Vitex-polygama.jpg” />
        Vitex polygama extract
        (Vitex negundo L. var. cannabifolia (Sieb. et Zucc.) Hand.-Mazz)

        1. Antiinflammatory Herbal Supplements
        2. Antioxidant And Hepatoprotective Activities Of The Fractions Of Ficus Microcarpa Using In Vitro And Ex Vivo Models
        3. Biological Activities Of A New Compound Isolated From The Aerial Parts Of Vitex Agnus Castus L.
        4. Effects Of Vitex Pubescens On Pregnant Rats
        5. Ethnopharmacological And Biotechnological Significance Of Vitex
        6. Hyperprogesteronemia In Response To Vitex Fischeri Consumption In Wild Chimpanzees (Pan Troglodytes Schweinfurthii)
        7. Phytochemical Profile And Analgesic Evaluation Of Vitex Cymosa Leaf Extracts
        8. The Genus Vitex: An Overview Of Iridoids As Chemotaxonomic Marker
        9. Three Triterpenoids From The Leaf Extract Of Vitex Doniana (Verbenaceae)

        ” alt=”” width=”360″ height=”384″ data-src=”https://theinterstellarplan.com/wp-content/uploads/2020/07/Withaferin-A.jpg” />

        Withaferin A
        (Ashwagandha extract)

        1. Anticancer Phytocompounds: Experimental And Clinical Updates
        2. Development Of A Goat Model For Evaluation Of Withaferin A: Cervical Implants For The Treatment Of Cervical Intraepithelial Neoplasia
        3. Indian Traditional Ayurvedic Treatment Regime For Novel Coronavirus , Covid-19
        4. Insights Into Bovine Endometritis With Special Reference To Phytotherapy
        5. Nrf2 Activator Pb125® As A Potential Therapeutic Agent Against Covid-19
        6. Prospect Of Indian Herbs As Sources Of Antioxidants In Combating Oxidative Stress.
        7. Secondary Metabolites Of Traditional Medical Plants: A Case Study Of Ashwagandha (Withania Somnifera)
        8. Utilization Of Ashwagandha (Withania Somnifera) Root Powder In Formulation Of Health Foods
        9. Withania Somnifera (Linn.) Dunal: A Review Of Chemical And Pharmacological Diversity

        ” alt=”” width=”335″ height=”318″ data-src=”https://theinterstellarplan.com/wp-content/uploads/2020/07/Withanolide-B.jpg” />
        Withanolide
        (Ashwagandha extract)

        1. Secondary Metabolites Of Traditional Medical Plants: A Case Study Of Ashwagandha (Withania Somnifera)
        2. Utilization Of Ashwagandha (Withania Somnifera) Root Powder In Formulation Of Health Foods


        Withanolide B
        (Ashwagandha extract)

        1. Secondary Metabolites Of Traditional Medical Plants: A Case Study Of Ashwagandha (Withania Somnifera)

        Withanone
        (Ashwagandha extract)

        Withanone from Withania somnifera May Inhibit Novel Coronavirus (COVID-19) Entry by Disrupting Interactions between Viral S-Protein Receptor Binding Domain and Host ACE2 Receptor

        Newly emerged COVID-19 has been shown to engage the host cell ACE2 through its spike protein receptor binding domain (RBD). Here we show that natural phytochemical from a medicinal herb, Withania somnifera, have distinct effects on viral RBD and host ACE2 receptor complex.

        Methods

        We employed molecular docking to screen thousands of phytochemicals against the ACE2-RBD complex, performed molecular dynamics (MD) simulation, and estimated the electrostatic component of binding free energy, along with the computation of salt bridge electrostatics.

        Results

        We report that W. somnifera compound, Withanone, docked very well in the binding interface of AEC2-RBD complex, and was found to move slightly towards the interface centre on simulation. Withanone significantly decreased electrostatic component of binding free energies of ACE2-RBD complex. Two salt bridges were also identified at the interface; incorporation of Withanone destabilized these salt bridges and decreased their occupancies. We postulate, such an interruption of electrostatic interactions between the RBD and ACE2 would block or weaken COVID-19 entry and its subsequent infectivity.

        Conclusion

        Our data, for the first time, show that natural phytochemicals could well be the viable options for controlling COVID-19 entry into host cells, and W. somnifera may be the first choice of herbs in these directions to curb the COVID-19 infectivity.


        Wogonin
        (Scutellaria baicalensis extract（Radix Scutellariae)

        1. Advances Of Wogonin, An Extract From Scutellaria Baicalensis, For The Treatment Of Multiple Tumors
        2. Anticonvulsant Effect Of Wogonin Isolated From Scutellaria Baicalensis
        3. Anti-Hepatitis B virus Activity Of Wogonin In Vitro And In Vivo
        4. Anti-Hepatitis B virus Effects Of Wogonin Isolated From Scutellaria Baicalensis
        5. Antioxidative And Anti-Inflammatory Activities Of Polyhydroxyflavonoids Of Scutellaria Baicalensis Georgi
        6. Antitumor Actions Of Baicalein And Wogonin In Ht-29 Human Colorectal Cancer Cells
        7. Antiviral Chinese Medicinal Herbs Against Respiratory Syncytial virus
        8. Flavonoid Pharmacokinetics And Tissue Distribution After Repeated Dosing Of The Roots Of Scutellaria Baicalensis In Rats
        9. Free Radical Scavenging And Antioxidant Activities Of Flavonoids Extracted From The Radix Of Scutellaria Baicalensis Georgi
        10. Isolation And Purification Of Baicalein, Wogonin And Oroxylin A From The Medicinal Plant Scutellaria Baicalensis By High-Speed Counter-Current Chromatography
        11. Potent Inhibition Of Monoamine Oxidase A By Decursin From Angelica Gigas Nakai And By Wogonin From Scutellaria Baicalensis Georgi
        12. Production Of Cytokines And Stimulation Of Resistance To viral Infection In Human Leukocytes By Scutellaria Baicalensis Flavones
        13. Relaxant Effect Induced By Wogonin From Scutellaria Baicalensis On Rat Isolated Uterine Smooth Muscle
        14. Scutellaria Baicalensis, The Golden Herb From The Garden Of Chinese Medicinal Plants
        15. The Anti-Inflammatory Activity Of Scutellaria Rivularis Extracts And Its Active Components, Baicalin, Baicalein And Wogonin
        16. Therapeutic Potential Of Wogonin: A Naturally Occurring Flavonoid
        17. Wogonin A Promising Component Of Scutellaria Baicalensis: A Review On Its Chemistry, Pharmacokinetics And Biological Activities
        18. Wogonin, A Flavonoid Isolated From Scutellaria Baicalensis, Has Anti-viral Activities Against Influenza Infection Via Modulation Of Ampk Pathways.
        19. Wogonin, An Active Ingredient Of Chinese Herb Medicine Scutellaria Baicalensis, Inhibits The Mobility And Invasion Of Human Gallbladder Carcinoma Gbc-Sd Cells By …

        Wrinkled Gianthyssop Herb extract
        (Agastache rugosa (Fisch. et Mey.) O. Ktze.)

        1. Phytochemistry And Bioactivity Of Aromatic And Medicinal Plants From The Genus Agastache (Lamiaceae)
        2. The Experience Of Treating Patients With Pneumonia Secondary To The Coronavirus Disease 2019 Using The Guizhi Method Of Traditional Chinese Medicine

        yohimbine
        (Yohimbe Bark Extract)

        1. Adme Properties Of Herbal Medicines In Humans: Evidence, Challenges And Strategies
        2. Clinical Evidence Of Herb-Drug Interactions: A Systematic Review By The Natural Standard Research Collaboration
        3. Evaluation Of Phytochemical Composition In Selected Medicinal Plants And Potential Application As Antimicrobial Agent
        4. Herbal Medications And Vitamin Supplements
        5. Herbal Medicine: Potential For Intoxication And Interactions With Conventional Drugs
        6. Interactions Between Nutraceuticals/Nutrients And Therapeutic Drugs
        7. Risks Associated With The Use Of Herbs And Other Dietary Supplements
        8. The Traditional Use Of Medicinal Plants To Treat Sexually Transmitted Diseases
        9. Β-Carboline Alkaloids
        10. Antiviral compositions that include yohimbina as an active principle.

 

 

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